Latest SPHERA FUNDS MANAGEMENT LTD. Stock Portfolio
$711Million
Equity Portfolio Value
Last Reported on: 15 May, 2024
About SPHERA FUNDS MANAGEMENT LTD. and it’s 13F Hedge Fund Stock Holdings
SPHERA FUNDS MANAGEMENT LTD. is a hedge fund based in NEW YORK, NY. On 31-Mar-2022, the fund reported that it had an AUM (Regulated Assets under Management) of $789.8 Millions. In it's latest 13F Holdings report, SPHERA FUNDS MANAGEMENT LTD. reported an equity portfolio of $711.7 Millions as of 31 Mar, 2024.
The top stock holdings of SPHERA FUNDS MANAGEMENT LTD. are TEVA, SNY, NICE. The fund has invested 3.8% of it's portfolio in TEVA PHARMACEUTICAL INDS LTD and 3.4% of portfolio in SANOFI.
The fund managers got completely rid off INHIBRX INC (INBX), PRAXIS PRECISION MEDICINES I (PRAX) and MADRIGAL PHARMACEUTICALS INC (MDGL) stocks. They significantly reduced their stock positions in CARTESIAN THERAPEUTICS INC (SELB), ASTRIA THERAPEUTICS INC (ATXS) and ALPINE IMMUNE SCIENCES INC (ALPN). SPHERA FUNDS MANAGEMENT LTD. opened new stock positions in JASPER THERAPEUTICS INC (JSPR), PRAXIS PRECISION MEDICINES I (PRAX) and CYBIN INC (CYBN). The fund showed a lot of confidence in some stocks as they added substantially to PERSPECTIVE THERAPEUTICS INC, VENTYX BIOSCIENCES INC (VTYX) and SAREPTA THERAPEUTICS INC (SRPT).
The top stock holdings of SPHERA FUNDS MANAGEMENT LTD. are TEVA, SNY, NICE. The fund has invested 3.8% of it's portfolio in TEVA PHARMACEUTICAL INDS LTD and 3.4% of portfolio in SANOFI.
The fund managers got completely rid off INHIBRX INC (INBX), PRAXIS PRECISION MEDICINES I (PRAX) and MADRIGAL PHARMACEUTICALS INC (MDGL) stocks. They significantly reduced their stock positions in CARTESIAN THERAPEUTICS INC (SELB), ASTRIA THERAPEUTICS INC (ATXS) and ALPINE IMMUNE SCIENCES INC (ALPN). SPHERA FUNDS MANAGEMENT LTD. opened new stock positions in JASPER THERAPEUTICS INC (JSPR), PRAXIS PRECISION MEDICINES I (PRAX) and CYBIN INC (CYBN). The fund showed a lot of confidence in some stocks as they added substantially to PERSPECTIVE THERAPEUTICS INC, VENTYX BIOSCIENCES INC (VTYX) and SAREPTA THERAPEUTICS INC (SRPT).
New Buys
| Ticker | $ Bought |
|---|---|
| JASPER THERAPEUTICS INC | 14,833,900 |
| PRAXIS PRECISION MEDICINES I | 10,809,000 |
| CYBIN INC | 10,577,900 |
| OUTLOOK THERAPEUTICS INC | 6,822,860 |
| APPLIED MATLS INC | 6,599,360 |
| CAMTEK LTD | 6,275,130 |
| 4D MOLECULAR THERAPEUTICS IN | 5,166,450 |
| CATALYST PHARMACEUTICALS INC | 4,590,720 |
New stocks bought by SPHERA FUNDS MANAGEMENT LTD.
Additions
| Ticker | % Inc. |
|---|---|
| PERSPECTIVE THERAPEUTICS INC | 48,373 |
| VENTYX BIOSCIENCES INC | 451 |
| SAREPTA THERAPEUTICS INC | 344 |
| VIGIL NEUROSCIENCE INC | 223 |
| PRIME MEDICINE INC | 177 |
| SENTINELONE INC | 158 |
| BRIDGEBIO PHARMA INC | 107 |
| JFROG LTD | 104 |
Additions to existing portfolio by SPHERA FUNDS MANAGEMENT LTD.
Reductions
| Ticker | % Reduced |
|---|---|
| CARTESIAN THERAPEUTICS INC | -96.67 |
| ASTRIA THERAPEUTICS INC | -90.2 |
| ALPINE IMMUNE SCIENCES INC | -80.91 |
| ADVANCED MICRO DEVICES INC | -78.17 |
| NOVA LTD | -73.4 |
| ICL GROUP LTD | -68.93 |
| TOWER SEMICONDUCTOR LTD | -66.00 |
| SPRINGWORKS THERAPEUTICS INC | -58.73 |
SPHERA FUNDS MANAGEMENT LTD. reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| RIGEL PHARMACEUTICALS INC | -1,780,780 |
| GRACELL BIOTECHNOLOGIES INC | -5,049,480 |
| PRAXIS PRECISION MEDICINES I | -7,329,810 |
| COGENT BIOSCIENCES INC | -1,524,100 |
| INHIBRX INC | -8,608,940 |
| ARROWHEAD PHARMACEUTICALS IN | -4,433,910 |
| PTC THERAPEUTICS INC | -3,762,630 |
| ORIC PHARMACEUTICALS INC | -1,166,560 |
SPHERA FUNDS MANAGEMENT LTD. got rid off the above stocks
Current Stock Holdings of SPHERA FUNDS MANAGEMENT LTD.
Last Reported on: 15 May, 2024| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options |
|---|---|---|---|---|---|---|---|
| AAPL | APPLE INC | 0.42 | 17,500 | 3,000,900 | NEW | ||
| ABBV | ABBVIE INC | 0.97 | 38,000 | 6,919,800 | REDUCED | -17.39 | |
| ACAD | ACADIA PHARMACEUTICALS INC | 0.32 | 125,000 | 2,311,250 | NEW | ||
| AKRO | AKERO THERAPEUTICS INC | 0.57 | 160,445 | 4,052,840 | NEW | ||
| ALEC | ALECTOR INC | 0.47 | 560,000 | 3,371,200 | NEW | ||
| ALPN | ALPINE IMMUNE SCIENCES INC | 0.25 | 44,841 | 1,777,500 | REDUCED | -80.91 | |
| AMAT | APPLIED MATLS INC | 0.93 | 32,000 | 6,599,360 | NEW | ||
| AMD | ADVANCED MICRO DEVICES INC | 0.28 | 11,000 | 1,985,390 | REDUCED | -78.17 | |
| AMLX | AMYLYX PHARMACEUTICALS INC | 0.11 | 267,250 | 758,990 | ADDED | 45.52 | |
| AMZN | AMAZON COM INC | 1.38 | 54,432 | 9,818,440 | REDUCED | -2.23 | |
| APLT | APPLIED THERAPEUTICS INC | 0.59 | 619,029 | 4,209,400 | NEW | ||
| APRE | APREA THERAPEUTICS INC | 0.25 | 270,000 | 1,806,300 | NEW | ||
| ARBE | ARBE ROBOTICS LTD | 0.01 | 43,165 | 90,215 | UNCHANGED | 0.00 | |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| ATXS | ASTRIA THERAPEUTICS INC | 0.22 | 112,842 | 1,588,250 | REDUCED | -90.2 | |
| AVGO | BROADCOM INC | 0.19 | 1,001 | 1,326,740 | REDUCED | -44.39 | |
| AZN | ASTRAZENECA PLC | 1.81 | 190,060 | 12,876,600 | ADDED | 5.55 | |
| BBIO | BRIDGEBIO PHARMA INC | 2.55 | 585,956 | 18,117,800 | ADDED | 107 | |
| BIIB | BIOGEN INC | 2.14 | 70,646 | 15,233,400 | ADDED | 52.43 | |
| CAMT | CAMTEK LTD | 0.88 | 74,909 | 6,275,130 | NEW | ||
| CGEN | COMPUGEN LTD | 0.28 | 769,239 | 1,984,640 | UNCHANGED | 0.00 | |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 1.63 | 276,996 | 11,625,500 | REDUCED | -12.24 | |
| COGT | COGENT BIOSCIENCES INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| CPRX | CATALYST PHARMACEUTICALS INC | 0.64 | 288,000 | 4,590,720 | NEW | ||
| CRBP | CORBUS PHARMACEUTICALS HLDGS | 0.19 | 35,000 | 1,373,400 | NEW | ||
| CYBN | CYBIN INC | 1.49 | 25,581,400 | 10,577,900 | NEW | ||
| CYTK | CYTOKINETICS INC | 2.78 | 281,671 | 19,748,000 | ADDED | 25.85 | |
| DAWN | DAY ONE BIOPHARMACEUTICALS I | 1.14 | 492,627 | 8,138,200 | REDUCED | -3.97 | |
| ELEV | ELEVATION ONCOLOGY INC | 0.31 | 430,000 | 2,205,900 | REDUCED | -52.22 | |
| ENPH | ENPHASE ENERGY INC | 0.80 | 47,183 | 5,708,200 | ADDED | 35.58 | |
| ESTC | ELASTIC N V | 0.28 | 20,000 | 2,004,800 | NEW | ||
| ETNB | 89BIO INC | 0.84 | 515,882 | 6,004,870 | ADDED | 26.23 | |
| FDMT | 4D MOLECULAR THERAPEUTICS IN | 0.73 | 162,161 | 5,166,450 | NEW | ||
| FIVN | FIVE9 INC | 0.24 | 27,500 | 1,708,020 | ADDED | 83.33 | |
| FRLN | FREELINE THERAPEUTICS HLDGS | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| FROG | JFROG LTD | 1.39 | 224,381 | 9,922,130 | ADDED | 104 | |
| FUSN | FUSION PHARMACEUTICALS INC | 1.34 | 449,041 | 9,573,550 | REDUCED | -58.64 | |
| GERN | GERON CORP | 0.18 | 384,356 | 1,268,380 | NEW | ||
| GILD | GILEAD SCIENCES INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| GLBE | GLOBAL E ONLINE LTD | 1.07 | 208,784 | 7,589,300 | REDUCED | -22.61 | |
| GLUE | MONTE ROSA THERAPEUTICS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| GOSS | GOSSAMER BIO INC | 0.17 | 1,027,130 | 1,212,020 | REDUCED | -23.24 | |
| GRCL | GRACELL BIOTECHNOLOGIES INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| GSK | GSK PLC | 0.60 | 100,000 | 4,287,000 | UNCHANGED | 0.00 | |
| HOWL | WEREWOLF THERAPEUTICS INC | 0.57 | 626,810 | 4,061,730 | UNCHANGED | 0.00 | |
| ICL | ICL GROUP LTD | 0.10 | 130,475 | 701,956 | REDUCED | -68.93 | |
| IMTX | IMMATICS N.V | 0.98 | 666,111 | 7,000,830 | ADDED | 7.25 | |
| IMTX | IMMATICS N.V | 0.04 | 100,000 | 270,000 | UNCHANGED | 0.00 | |
| INBX | INHIBRX INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| INCY | INCYTE CORP | 0.72 | 89,556 | 5,102,000 | UNCHANGED | 0.00 | |
| INZY | INOZYME PHARMA INC | 1.48 | 1,372,910 | 10,516,500 | REDUCED | -12.16 | |
| JNJ | JOHNSON & JOHNSON | 1.77 | 79,831 | 12,628,500 | UNCHANGED | 0.00 | |
| JSPR | JASPER THERAPEUTICS INC | 2.08 | 505,242 | 14,833,900 | NEW | ||
| JSPR | JASPER THERAPEUTICS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| KURA | KURA ONCOLOGY INC | 1.83 | 610,826 | 13,028,900 | REDUCED | -13.15 | |
| KZR | KEZAR LIFE SCIENCES INC | 0.26 | 2,051,680 | 1,849,790 | UNCHANGED | 0.00 | |
| LLY | ELI LILLY & CO | 1.55 | 14,190 | 11,039,300 | UNCHANGED | 0.00 | |
| LVTX | LAVA THERAPEUTICS NV | 0.17 | 367,582 | 1,224,050 | NEW | ||
| MDGL | MADRIGAL PHARMACEUTICALS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| MDWD | MEDIWOUND LTD | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| META | META PLATFORMS INC | 1.74 | 25,439 | 12,352,700 | REDUCED | -25.84 | |
| MORF | MORPHIC HLDG INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| MRK | MERCK & CO INC | 1.92 | 103,600 | 13,670,000 | REDUCED | -16.18 | |
| MRUS | MERUS N V | 0.94 | 149,333 | 6,724,460 | REDUCED | -35.17 | |
| MSFT | MICROSOFT CORP | 1.63 | 27,548 | 11,590,000 | ADDED | 15.51 | |
| NICE | NICE LTD | 3.14 | 85,881 | 22,382,300 | ADDED | 26.82 | |
| NTR | NUTRIEN LTD | 0.27 | 35,730 | 1,940,500 | NEW | ||
| NVMI | NOVA LTD | 0.88 | 35,106 | 6,227,100 | REDUCED | -73.4 | |
| NVO | NOVO-NORDISK A S | 1.50 | 83,080 | 10,667,500 | REDUCED | -10.74 | |
| NVS | NOVARTIS AG | 0.68 | 50,000 | 4,836,500 | REDUCED | -16.67 | |
| ORIC | ORIC PHARMACEUTICALS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| OTLK | OUTLOOK THERAPEUTICS INC | 0.96 | 571,429 | 6,822,860 | NEW | ||
| PANW | PALO ALTO NETWORKS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| PFE | PFIZER INC | 0.35 | 90,000 | 2,497,500 | UNCHANGED | 0.00 | |
| PHVS | PHARVARIS N V | 1.28 | 392,877 | 9,079,390 | ADDED | 60.36 | |
| PLRX | PLIANT THERAPEUTICS INC | 0.54 | 258,554 | 3,852,460 | ADDED | 33.58 | |
| PMN | PROMIS NEUROSCIENCES INC | 0.49 | 1,834,050 | 3,503,030 | ADDED | 0.00 | |
| PRAX | PRAXIS PRECISION MEDICINES I | 1.52 | 177,139 | 10,809,000 | NEW | ||
| PRAX | PRAXIS PRECISION MEDICINES I | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| PTCT | PTC THERAPEUTICS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| QCOM | QUALCOMM INC | 0.36 | 15,000 | 2,539,500 | NEW | ||
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 1.56 | 238,544 | 11,137,600 | ADDED | 18.65 | |
| RCKT | ROCKET PHARMACEUTICALS INC | 0.70 | 183,722 | 4,949,470 | REDUCED | -3.7 | |
| REPL | REPLIMUNE GROUP INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| RIGL | RIGEL PHARMACEUTICALS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| RZLT | REZOLUTE INC | 0.36 | 996,710 | 2,541,610 | UNCHANGED | 0.00 | |
| S | SENTINELONE INC | 1.80 | 550,818 | 12,839,600 | ADDED | 158 | |
| SEDG | SOLAREDGE TECHNOLOGIES INC | 0.40 | 40,175 | 2,851,620 | REDUCED | -16.3 | |
| SELB | CARTESIAN THERAPEUTICS INC | 0.07 | 25,071 | 488,889 | REDUCED | -96.67 | |
| SNDX | SYNDAX PHARMACEUTICALS INC | 2.72 | 812,964 | 19,348,500 | ADDED | 5.17 | |
| SNY | SANOFI | 3.41 | 499,515 | 24,276,400 | UNCHANGED | 0.00 | |
| SRPT | SAREPTA THERAPEUTICS INC | 1.01 | 55,614 | 7,199,790 | ADDED | 344 | |
| SWTX | SPRINGWORKS THERAPEUTICS INC | 0.49 | 70,269 | 3,458,640 | REDUCED | -58.73 | |
| TBLA | TABOOLA.COM LTD | 0.74 | 1,191,070 | 5,288,350 | REDUCED | -30.95 | |
| TEVA | TEVA PHARMACEUTICAL INDS LTD | 3.75 | 1,889,700 | 26,663,700 | REDUCED | -23.47 | |
| TSEM | TOWER SEMICONDUCTOR LTD | 0.84 | 179,600 | 6,007,620 | REDUCED | -66.00 | |
| UPWK | UPWORK INC | 0.20 | 117,000 | 1,434,420 | REDUCED | -53.72 | |
| VIGL | VIGIL NEUROSCIENCE INC | 0.83 | 1,730,410 | 5,900,710 | ADDED | 223 | |
| VRNS | VARONIS SYS INC | 0.13 | 20,000 | 943,400 | NEW | ||
| VSTA | VISTAGEN THERAPEUTICS INC | 0.60 | 808,550 | 4,269,140 | UNCHANGED | 0.00 | |
| VTYX | VENTYX BIOSCIENCES INC | 0.77 | 992,749 | 5,460,120 | ADDED | 451 | |
| WIX | WIX COM LTD | 1.02 | 52,877 | 7,269,530 | REDUCED | -8.00 | |
| PERSPECTIVE THERAPEUTICS INC | 2.08 | 12,443,600 | 14,807,900 | ADDED | 48,373 | ||
| MINERALYS THERAPEUTICS INC | 1.20 | 658,803 | 8,505,150 | REDUCED | -11.4 | ||
| SHL TELEMEDICINE LTD | 0.54 | 632,456 | 3,857,980 | UNCHANGED | 0.00 | ||
| DISC MEDICINE INC | 0.43 | 48,886 | 3,043,640 | NEW | |||
| ENLIGHT RENEWABLE ENERGY LTD | 0.40 | 169,280 | 2,864,220 | UNCHANGED | 0.00 | ||
| CARGO THERAPEUTICS INC | 0.23 | 75,000 | 1,674,000 | UNCHANGED | 0.00 | ||
| PRIME MEDICINE INC | 0.20 | 205,242 | 1,436,690 | ADDED | 177 | ||
| ALTO NEUROSCIENCE INC | 0.07 | 30,500 | 468,175 | NEW | |||
| APOGEE THERAPEUTICS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 |