Latest Opaleye Management Inc. Stock Portfolio
$436Million
Equity Portfolio Value
Last Reported on: 15 May, 2024
About Opaleye Management Inc. and it’s 13F Hedge Fund Stock Holdings
Opaleye Management Inc. is a hedge fund based in BOSTON, MA. On 27-Mar-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $422 Millions. In it's latest 13F Holdings report, Opaleye Management Inc. reported an equity portfolio of $436.9 Millions as of 31 Mar, 2024.
The top stock holdings of Opaleye Management Inc. are OCUL, HROW, TGTX. The fund has invested 13.9% of it's portfolio in OCULAR THERAPEUTIX INC and 11.9% of portfolio in HARROW HEALTH INC.
The fund managers got completely rid off IDEAYA BIOSCIENCES INC (IDYA), BIOHAVEN LTD and ARCUTIS BIOTHERAPEUTICS INC (ARQT) stocks. They significantly reduced their stock positions in LARIMAR THERAPEUTICS INC (LRMR), ACELYRIN INC and MORPHOSYS AG (MOR). Opaleye Management Inc. opened new stock positions in JASPER THERAPEUTICS INC (JSPR), LYELL IMMUNOPHARMA INC (LYEL) and COMPASS THERAPEUTICS INC (CMPX). The fund showed a lot of confidence in some stocks as they added substantially to INTELLIA THERAPEUTICS INC (NTLA), SYROS PHARMACEUTICALS INC (SYRS) and APPLIED THERAPEUTICS (APLT).
The top stock holdings of Opaleye Management Inc. are OCUL, HROW, TGTX. The fund has invested 13.9% of it's portfolio in OCULAR THERAPEUTIX INC and 11.9% of portfolio in HARROW HEALTH INC.
The fund managers got completely rid off IDEAYA BIOSCIENCES INC (IDYA), BIOHAVEN LTD and ARCUTIS BIOTHERAPEUTICS INC (ARQT) stocks. They significantly reduced their stock positions in LARIMAR THERAPEUTICS INC (LRMR), ACELYRIN INC and MORPHOSYS AG (MOR). Opaleye Management Inc. opened new stock positions in JASPER THERAPEUTICS INC (JSPR), LYELL IMMUNOPHARMA INC (LYEL) and COMPASS THERAPEUTICS INC (CMPX). The fund showed a lot of confidence in some stocks as they added substantially to INTELLIA THERAPEUTICS INC (NTLA), SYROS PHARMACEUTICALS INC (SYRS) and APPLIED THERAPEUTICS (APLT).
New Buys
| Ticker | $ Bought |
|---|---|
| JASPER THERAPEUTICS INC | 12,788,400 |
| LYELL IMMUNOPHARMA INC | 7,481,650 |
| COMPASS THERAPEUTICS INC | 6,276,600 |
| SAVARA INC | 4,257,900 |
| REVANCE THERAPEUTICS INC | 3,862,200 |
| ZENTALIS PHARMACEUTICALS INC | 3,152,000 |
| ALLAKOS INC | 3,068,100 |
| IBIO INC | 2,760,800 |
New stocks bought by Opaleye Management Inc.
Additions
| Ticker | % Inc. |
|---|---|
| INTELLIA THERAPEUTICS INC | 157 |
| SYROS PHARMACEUTICALS INC | 119 |
| APPLIED THERAPEUTICS | 62.01 |
| ALIGOS THERAPEUTICS INC | 25.67 |
| ARVINAS INC | 25.14 |
| NEWAMSTERDAM PHARMA COMPANY | 18.84 |
| CONTEXT THERAPEUTICS INC | 13.68 |
| VENTYX BIOSCIENCES INC | 12.72 |
Additions to existing portfolio by Opaleye Management Inc.
Reductions
| Ticker | % Reduced |
|---|---|
| LARIMAR THERAPEUTICS INC | -72.03 |
| ACELYRIN INC | -61.89 |
| MORPHOSYS AG | -55.17 |
| CRINETICS PHARMACEUTICALS INC | -31.71 |
| CATALYST PHARMACEUTICALS INC | -20.11 |
| GOSSAMER BIO INC | -18.18 |
| UROGEN PHARMA LTD | -15.62 |
| RHYTHM PHARMACEUTICALS INC | -15.57 |
Opaleye Management Inc. reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| ARCUTIS BIOTHERAPEUTICS INC | -6,330,800 |
| MARINUS PHARMACEUTICALS INC | -6,125,240 |
| JASPER THERAPEUTICS INC | -3,144,430 |
| IDEAYA BIOSCIENCES INC | -11,083,200 |
| SUTRO BIOPHARMA INC | -1,293,400 |
| BIOHAVEN LTD | -8,560,000 |
| KALVISTA PHARMACEUTICALS INC | -1,837,500 |
| KINIKSA PHARMACEUTICALS LTD | -640,210 |
Opaleye Management Inc. got rid off the above stocks
Current Stock Holdings of Opaleye Management Inc.
Last Reported on: 15 May, 2024| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options |
|---|---|---|---|---|---|---|---|
| ALGS | ALIGOS THERAPEUTICS INC | 0.37 | 1,630,000 | 1,597,400 | ADDED | 25.67 | |
| ALLK | ALLAKOS INC | 0.70 | 2,435,000 | 3,068,100 | NEW | ||
| APLT | APPLIED THERAPEUTICS | 0.84 | 1,770,000 | 3,659,880 | ADDED | 62.01 | |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| ARVN | ARVINAS INC | 3.12 | 330,000 | 13,622,400 | ADDED | 25.14 | |
| BDSX | BIODESIX | 0.17 | 534,657 | 764,560 | ADDED | 7.69 | |
| CDXS | CODEXIS INC | 2.49 | 3,120,000 | 10,888,800 | ADDED | 2.45 | |
| CMPX | COMPASS THERAPEUTICS INC | 1.44 | 3,170,000 | 6,276,600 | NEW | ||
| CNTX | CONTEXT THERAPEUTICS INC | 0.35 | 1,108,360 | 1,529,530 | ADDED | 13.68 | |
| CPRX | CATALYST PHARMACEUTICALS INC | 3.66 | 1,004,360 | 16,009,400 | REDUCED | -20.11 | |
| CRNX | CRINETICS PHARMACEUTICALS INC | 0.05 | 210,000 | 210,000 | REDUCED | -31.71 | |
| DSGN | DESIGN THERAPEUTICS INC | 0.10 | 113,038 | 455,543 | NEW | ||
| ETON | ETON PHARMACEUTICALS INC | 2.10 | 2,445,780 | 9,171,680 | REDUCED | -3.32 | |
| EWTX | EDGEWISE THERAPEUTICS INC | 2.78 | 665,000 | 12,129,600 | REDUCED | -4.86 | |
| FDMT | 4D MOLECULAR THERAPEUTICS INC | 2.51 | 344,123 | 10,963,800 | ADDED | 11.55 | |
| FULC | FULCRUM THERAPEUTICS INC | 0.28 | 130,000 | 1,227,200 | UNCHANGED | 0.00 | |
| GKOS | GLAUKOS CORP | 0.18 | 8,576 | 808,631 | NEW | ||
| GOSS | GOSSAMER BIO INC | 0.74 | 8,000,000 | 3,212,930 | UNCHANGED | 0.00 | |
| GOSS | GOSSAMER BIO INC | 0.66 | 2,440,110 | 2,879,330 | REDUCED | -18.18 | |
| HROW | HARROW HEALTH INC | 11.87 | 3,920,600 | 51,869,500 | ADDED | 2.63 | |
| IBIO | IBIO INC | 0.63 | 680,000 | 2,760,800 | NEW | ||
| IDYA | IDEAYA BIOSCIENCES INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 3.04 | 897,000 | 13,293,500 | UNCHANGED | 0.00 | |
| JSPR | JASPER THERAPEUTICS INC | 2.93 | 435,573 | 12,788,400 | NEW | ||
| JSPR | JASPER THERAPEUTICS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| KALV | KALVISTA PHARMACEUTICALS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| KNSA | KINIKSA PHARMACEUTICALS LTD | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| KROS | KEROS THERAPEUTICS INC | 5.57 | 367,500 | 24,328,500 | ADDED | 2.8 | |
| LQDA | LIQUIDIA CORPORATION | 1.33 | 395,000 | 5,826,250 | REDUCED | -11.24 | |
| LRMR | LARIMAR THERAPEUTICS INC | 0.30 | 174,413 | 1,323,800 | REDUCED | -72.03 | |
| LYEL | LYELL IMMUNOPHARMA INC | 1.71 | 3,355,000 | 7,481,650 | NEW | ||
| MOR | MORPHOSYS AG | 0.27 | 65,000 | 1,179,100 | REDUCED | -55.17 | |
| MRNS | MARINUS PHARMACEUTICALS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| NAMS | NEWAMSTERDAM PHARMA COMPANY | 1.71 | 315,388 | 7,458,930 | ADDED | 18.84 | |
| NTLA | INTELLIA THERAPEUTICS INC | 1.61 | 255,000 | 7,015,050 | ADDED | 157 | |
| OCUL | OCULAR THERAPEUTIX INC | 13.86 | 6,653,140 | 60,543,600 | ADDED | 9.61 | |
| PCVX | VAXCYTE INC | 1.33 | 85,000 | 5,806,350 | REDUCED | -5.56 | |
| PGEN | PRECIGEN INC | 0.31 | 947,500 | 1,373,880 | REDUCED | -6.42 | |
| PMVP | PMV PHARMACEUTICALS INC | 0.18 | 471,481 | 802,130 | NEW | ||
| PTGX | PROTAGONIST THERAPEUTICS INC | 0.75 | 112,700 | 3,260,410 | UNCHANGED | 0.00 | |
| RGLS | REGULUS THERAPEUTICS INC | 0.11 | 170,308 | 490,487 | NEW | ||
| RLMD | RELMADA THERAPEUTICS INC | 0.81 | 759,000 | 3,529,350 | REDUCED | -13.45 | |
| RPTX | REPARE THERAPEUTICS INC | 0.07 | 67,561 | 318,212 | NEW | ||
| RVNC | REVANCE THERAPEUTICS INC | 0.88 | 785,000 | 3,862,200 | NEW | ||
| RYTM | RHYTHM PHARMACEUTICALS INC | 5.11 | 515,000 | 22,315,000 | REDUCED | -15.57 | |
| STRO | SUTRO BIOPHARMA INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| SVRA | SAVARA INC | 0.97 | 855,000 | 4,257,900 | NEW | ||
| SYRS | SYROS PHARMACEUTICALS INC | 0.96 | 787,545 | 4,212,830 | ADDED | 119 | |
| TARA | PROTARA THERAPEUTICS INC | 2.47 | 2,692,590 | 10,797,300 | UNCHANGED | 0.00 | |
| TGTX | TG THERAPEUTICS INC | 7.94 | 2,280,000 | 34,678,800 | ADDED | 2.93 | |
| TRVI | TREVI THERAPEUTICS INC | 2.09 | 2,645,000 | 9,125,250 | ADDED | 4.34 | |
| URGN | UROGEN PHARMA LTD | 0.93 | 270,000 | 4,050,000 | REDUCED | -15.62 | |
| VSTM | VERASTEM INC | 0.57 | 211,400 | 2,494,520 | UNCHANGED | 0.00 | |
| VTYX | VENTYX BIOSCIENCES INC | 1.62 | 1,285,000 | 7,067,500 | ADDED | 12.72 | |
| XOMA | XOMA CORP DEL | 1.38 | 250,000 | 6,012,500 | UNCHANGED | 0.00 | |
| ZNTL | ZENTALIS PHARMACEUTICALS INC | 0.72 | 200,000 | 3,152,000 | NEW | ||
| ACELYRIN INC | 2.44 | 1,580,000 | 10,665,000 | REDUCED | -61.89 | ||
| NYXOAH S A | 0.99 | 320,000 | 4,316,800 | REDUCED | -7.19 | ||
| BIOHAVEN LTD | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 |