Latest ARCH VENTURE CORP Stock Portfolio

$1.10Billion | No. of Holdings #12

ARCH VENTURE CORP Performance

2026 Q2+10.92%
YTD+17.03%
2025+73.87%

About ARCH VENTURE CORP and 13F Hedge Fund Stock Holdings

On 2026-08-14, the fund reported it's updated stock portfolio. In the 13F Holdings report, ARCH Venture Management, LLC reported an equity portfolio of $1.1 Billions as of 30 Jun, 2026. <br><br> The top stock holdings of ARCH Venture Management, LLC are , BEAM, . The fund has invested 15.9% of it's portfolio in PARABILIS MEDICINES INC and 14.2% of portfolio in BEAM THERAPEUTICS INC. <br><br> The fund managers got completely rid off Q32 BIO INC stocks. They significantly reduced their stock positions in VIR BIOTECHNOLOGY INC (VIR). ARCH Venture Management, LLC opened new stock positions in PARABILIS MEDICINES INC.
ARCH VENTURE CORP Equity Portfolio Value
Last Reported on: 14 Aug, 2026
$1.10Billion
  as of Aug 14, 2026

ARCH VENTURE CORP Annual Return Estimates Vs S&P 500

Our best estimate is that ARCH Venture Management, LLC made a return of 10.92% in the last quarter. In trailing 12 months, it's portfolio return was 158.62%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
parabilis medicines inc175,518,000
seaport therapeutics inc136,600,000
boundless bio inc6,735,240

New stocks bought by ARCH VENTURE CORP

Additions

No additions were made to existing positions by ARCH VENTURE CORP

Reductions

Ticker% Reduced
vir biotechnology inc-1.72

ARCH VENTURE CORP reduced stake in above stock

Sold off

Ticker$ Sold
q32 bio inc-2,057,490

ARCH VENTURE CORP got rid off the above stocks

Sector Distribution

ARCH Venture Management, LLC has about 57.3% of it's holdings in Others sector.

  • Others
  • Healthcare
Sector%
Others57.3
Healthcare42.7

Market Cap. Distribution

ARCH Venture Management, LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.

  • UNALLOCATED
  • MID-CAP
  • SMALL-CAP
Category%
UNALLOCATED57.3
MID-CAP26.7
SMALL-CAP15.9

Stocks belong to which Index?

About 41.9% of the stocks held by ARCH Venture Management, LLC either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • RUSSELL 2000
Index%
Others58.1
RUSSELL 200041.9
Top 5 Winners (%)%
TXG
10x genomics inc
80.6 %
BEAM
beam therapeutics inc
44.0 %
generate biomedicines inc
35.0 %
rapport therapeutics inc
33.2 %
VIR
vir biotechnology inc
13.6 %
Top 5 Winners ($)$
BEAM
beam therapeutics inc
47.6 M
rapport therapeutics inc
38.7 M
VIR
vir biotechnology inc
15.8 M
ERAS
erasca inc
15.2 M
generate biomedicines inc
8.5 M
Top 5 Losers (%)%
GOSS
gossamer bio inc
-49.9 %
LYEL
lyell immunopharma inc
-30.1 %
Top 5 Losers ($)$
LYEL
lyell immunopharma inc
-19.6 M
GOSS
gossamer bio inc
-1.3 M

ARCH VENTURE CORP Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of ARCH VENTURE CORP

ARCH Venture Management, LLC has 12 stocks in it's portfolio. LYEL proved to be the most loss making stock for the portfolio. BEAM was the most profitable stock for ARCH Venture Management, LLC last quarter.

$1.10BTotal Value
13.00Positions
14 Aug, 2026Last Reported
Current holdings of Current Stock Holdings of ARCH VENTURE CORP, last reported on 14 Aug, 2026. Select a row with a linked ticker to view its historical trend.
ExpandHoldingsorted ascending% PortfolioShares Held$ Value% Change
Com
Parabilis Medicines Inc

Parabilis Medicines Inc

ARCH VENTURE CORP's holding in Parabilis Medicines Inc over time
15.95%6,412,780
$175.52M
15.95%
new position
Com
Rapport Therapeutics Inc

Rapport Therapeutics Inc

ARCH VENTURE CORP's holding in Rapport Therapeutics Inc over time
14.12%3,728,740
$155.38M
14.12%
unchanged 0 percentunchanged
Common Stock
Seaport Therapeutics Inc

Seaport Therapeutics Inc

ARCH VENTURE CORP's holding in Seaport Therapeutics Inc over time
12.41%6,294,950
$136.60M
12.41%
new position
Com
Maze Therapeutics Inc

Maze Therapeutics Inc

ARCH VENTURE CORP's holding in Maze Therapeutics Inc over time
11.18%4,120,050
$122.98M
11.18%
unchanged 0 percentunchanged
Com Shs
Generate Biomedicines Inc

Generate Biomedicines Inc

ARCH VENTURE CORP's holding in Generate Biomedicines Inc over time
2.98%1,944,430
$32.80M
2.98%
unchanged 0 percentunchanged
Com
Boundless Bio Inc

Boundless Bio Inc

ARCH VENTURE CORP's holding in Boundless Bio Inc over time
0.61%2,694,100
$6.74M
0.61%
new position
Com
Q32 Bio Inc

Q32 Bio Inc

ARCH VENTURE CORP's holding in Q32 Bio Inc over time
0%0.00
$0.00
0%
decreased 100 percentsold off