Latest ARCH VENTURE CORP Stock Portfolio

About ARCH VENTURE CORP and 13F Hedge Fund Stock Holdings

On 2026-02-17, the fund reported it's updated stock portfolio. In the 13F Holdings report, ARCH Venture Management, LLC reported an equity portfolio of $651.7 Millions as of 31 Dec, 2025.

The top stock holdings of ARCH Venture Management, LLC are , BEAM, . The fund has invested 26.2% of it's portfolio in MAZE THERAPEUTICS INC. and 19.3% of portfolio in BEAM THERAPEUTICS INC.

The fund managers got completely rid off CERO THERAPEUTICS HOLDINGS INC. (PBAX) stocks. ARCH Venture Management, LLC opened new stock positions in 10X GENOMICS INC. (TXG).

ARCH VENTURE CORP Annual Return Estimates Vs S&P 500

Performance

New Buys

Ticker	$ Bought
10x genomics inc.	12,029,300

New stocks bought by ARCH VENTURE CORP

Additions

No additions were made to existing positions by ARCH VENTURE CORP

Reductions

None of the existing positions were reduced by ARCH VENTURE CORP

Sold off

Ticker	$ Sold
cero therapeutics holdings inc.	-113,960

ARCH VENTURE CORP got rid off the above stocks

Sector Distribution

Sector	%
Healthcare	56.3
Others	43.7

Market Cap. Distribution

Category	%
UNALLOCATED	43.7
SMALL-CAP	28.8
MID-CAP	27.5

Stocks belong to which Index?

Index	%
RUSSELL 2000	50.6
Others	49.4

Top 5 Winners (%)		%
LYEL	lyell immunopharma inc.	89.5 %
ERAS	erasca inc.	70.6 %
	q32 bio inc.	67.7 %
	maze therapeutics inc.	59.8 %
GOSS	gossamer bio inc.	17.9 %

Top 5 Winners ($)		$
	maze therapeutics inc.	63.9 M
LYEL	lyell immunopharma inc.	40.1 M
ERAS	erasca inc.	17.0 M
BEAM	beam therapeutics inc.	15.7 M
VIR	vir biotechnology inc.	4.1 M

Top 5 Losers (%)		%

Top 5 Losers ($)		$

ARCH VENTURE CORP Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of ARCH VENTURE CORP

Last Reported on: 17 Feb, 2026

Ticker	Namesorted ascending	% Portfolio	Shares Held	$ Value	Type	% Change
BEAM	beam therapeutics inc.	19.31	4,540,130	125,852,000	unchanged	0.00

ERAS	erasca inc.	6.31	11,055,600	41,126,700	unchanged	0.00

GOSS	gossamer bio inc.	3.83	8,055,920	24,973,300	unchanged	0.00

LYEL	lyell immunopharma inc.	13.03	2,759,070	84,924,200	unchanged	0.00

PBAX	cero therapeutics holdings inc.	0.00	0.00	0.00	sold off	-100

TXG	10x genomics inc.	1.85	737,539	12,029,300	new

VIR	vir biotechnology inc.	11.95	12,916,700	77,887,500	unchanged	0.00

	maze therapeutics inc.	26.19	4,120,050	170,694,000	unchanged	0.00

	rapport therapeutics inc.	17.36	3,728,740	113,130,000	unchanged	0.00

	q32 bio inc.	0.16	320,482	1,064,000	unchanged	0.00