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Latest Crestline Management, LP Stock Portfolio

About Crestline Management, LP and 13F Hedge Fund Stock Holdings

Crestline Management, LP is a hedge fund based in FORT WORTH, TX. On 31-Mar-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $20.8 Billions. In it's latest 13F Holdings report, Crestline Management, LP reported an equity portfolio of $58.1 Millions as of 30 Sep, 2025.

The top stock holdings of Crestline Management, LP are DNLI, SANA, EGHT. The fund has invested 85.2% of it's portfolio in DENALI THERAPEUTICS INC and 11.1% of portfolio in SANA BIOTECHNOLOGY INC.

They significantly reduced their stock positions in SANA BIOTECHNOLOGY INC (SANA) and DENALI THERAPEUTICS INC (DNLI).

Crestline Management, LP Annual Return Estimates Vs S&P 500

New Buys

No new stocks were added by Crestline Management, LP

Additions

No additions were made to existing positions by Crestline Management, LP

Reductions

Ticker% Reduced
sana biotechnology inc-24.78
denali therapeutics inc-11.66

Crestline Management, LP reduced stake in above stock

Sold off

None of the stocks were completely sold off by Crestline Management, LP

Sector Distribution

Sector%
Healthcare96.4
Technology3.6

Market Cap. Distribution

Category%
MID-CAP85.3
SMALL-CAP14.7

Stocks belong to which Index?

Index%
RUSSELL 2000100
Top 5 Winners (%)%
SANA
sana biotechnology inc
30.0 %
EGHT
8x8 inc new
8.2 %
DNLI
denali therapeutics inc
3.8 %
Top 5 Winners ($)$
DNLI
denali therapeutics inc
2.0 M
SANA
sana biotechnology inc
2.0 M
EGHT
8x8 inc new
0.2 M
Top 5 Losers (%)%
Top 5 Losers ($)$

Crestline Management, LP Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Crestline Management, LP

Last Reported on: 14 Nov, 2025
TickerNamesorted ascending% PortfolioShares Held$ ValueType% ChangeOptions