Latest Crestline Management, LP Stock Portfolio
$92.53Million– No. of Holdings #3
Crestline Management, LP Performance:
2026 Q1: 9%YTD: 9%2025: -12.32%
Performance for 2026 Q1 is 9%, and YTD is 9%, and 2025 is -12.32%.
About Crestline Management, LP and 13F Hedge Fund Stock Holdings
Crestline Management, L.P. is a hedge fund based in Fort Worth, TX. On 2026-05-15, the fund reported it's updated stock portfolio. In the 13F Holdings report, Crestline Management, L.P. reported an equity portfolio of $92.5 Millions as of 31 Mar, 2026.
The top stock holdings of Crestline Management, L.P. are DNLI, SANA, EGHT. The fund has invested 91.7% of it's portfolio in DENALI THERAPEUTICS INC and 4.7% of portfolio in SANA BIOTECHNOLOGY INC.
The fund showed a lot of confidence in some stocks as they added substantially to 8X8 INC NEW (EGHT), DENALI THERAPEUTICS INC (DNLI) and SANA BIOTECHNOLOGY INC (SANA).
The top stock holdings of Crestline Management, L.P. are DNLI, SANA, EGHT. The fund has invested 91.7% of it's portfolio in DENALI THERAPEUTICS INC and 4.7% of portfolio in SANA BIOTECHNOLOGY INC.
The fund showed a lot of confidence in some stocks as they added substantially to 8X8 INC NEW (EGHT), DENALI THERAPEUTICS INC (DNLI) and SANA BIOTECHNOLOGY INC (SANA).
Crestline Management, LP Equity Portfolio Value
Last Reported on: 15 May, 2026
Crestline Management, LP Annual Return Estimates Vs S&P 500
Our best estimate is that Crestline Management, L.P. made a return of 9% in the last quarter. In trailing 12 months, it's portfolio return was 38.01%.
- Performance
- S&P 500
New Buys
Additions
| Ticker | % Inc. |
|---|---|
| 8x8 inc new | 100 |
| denali therapeutics inc | 57.31 |
| sana biotechnology inc | 23.8 |
Additions to existing portfolio by Crestline Management, LP
Reductions
Sold off
Sector Distribution
Crestline Management, L.P. has about 96.4% of it's holdings in Healthcare sector.
- Healthcare
- Technology
| Sector | % |
|---|---|
| Healthcare | 96.4 |
| Technology | 3.6 |
Market Cap. Distribution
Crestline Management, L.P. has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.
- MID-CAP
- SMALL-CAP
| Category | % |
|---|---|
| MID-CAP | 91.7 |
| SMALL-CAP | 8.3 |
Stocks belong to which Index?
About 100% of the stocks held by Crestline Management, L.P. either belong to S&P 500 or RUSSELL 2000 index.
- RUSSELL 2000
| Index | % |
|---|---|
| RUSSELL 2000 | 100 |
Crestline Management, LP Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Crestline Management, LP
Crestline Management, L.P. has 3 stocks in it's portfolio. SANA proved to be the most loss making stock for the portfolio. DNLI was the most profitable stock for Crestline Management, L.P. last quarter.
Last Reported on: 15 May, 2026