Latest Sarissa Capital Management LP Stock Portfolio

$157Million | No. of Holdings #9

Sarissa Capital Management LP Performance

2026 Q1+4.31%

YTD+4.31%

2025+3.94%

About Sarissa Capital Management LP and 13F Hedge Fund Stock Holdings

On 2026-05-15, the fund reported it's updated stock portfolio. In the 13F Holdings report, Sarissa Capital Management LP reported an equity portfolio of $157.6 Millions as of 31 Mar, 2026. <br><br> The top stock holdings of Sarissa Capital Management LP are INVA, IRWD, AMRN. The fund has invested 31.5% of it's portfolio in INNOVIVA INC and 20.5% of portfolio in IRONWOOD PHARMACEUTICALS INC. <br><br> They significantly reduced their stock positions in NEUROCRINE BIOSCIENCES INC (NBIX), CYTOKINETICS INC (CYTK) and IRONWOOD PHARMACEUTICALS INC (IRWD). The fund showed a lot of confidence in some stocks as they added substantially to BIOHAVEN LTD.

Sarissa Capital Management LP Equity Portfolio Value

Last Reported on: 15 May, 2026

$157Million

as of May 15, 2026

Sarissa Capital Management LP Annual Return Estimates Vs S&P 500

Our best estimate is that Sarissa Capital Management LP made a return of 4.31% in the last quarter. In trailing 12 months, it's portfolio return was 34.17%.

Performance
S&P 500

New Buys

No new stocks were added by Sarissa Capital Management LP

Additions

Ticker	% Inc.
biohaven ltd	9.74

Additions to existing portfolio by Sarissa Capital Management LP

Reductions

Ticker	% Reduced
neurocrine biosciences inc	-61.56
cytokinetics inc	-42.32
ironwood pharmaceuticals inc	-42.28
innoviva inc	-24.33
lantheus hldgs inc	-8.01

Sarissa Capital Management LP reduced stake in above stock

Sold off

None of the stocks were completely sold off by Sarissa Capital Management LP

Sector Distribution

Sarissa Capital Management LP has about 97% of it's holdings in Healthcare sector.

Healthcare
Others

Sector	%
Healthcare	97
Others	3

Market Cap. Distribution

Sarissa Capital Management LP has about 11.8% of it's portfolio invested in the large-cap and mega-cap stocks.

SMALL-CAP
MID-CAP
LARGE-CAP
UNALLOCATED

Category	%
SMALL-CAP	52
MID-CAP	32.9
LARGE-CAP	11.8
UNALLOCATED	3

Stocks belong to which Index?

About 71.9% of the stocks held by Sarissa Capital Management LP either belong to S&P 500 or RUSSELL 2000 index.

RUSSELL 2000
Others
S&P 500

Index	%
RUSSELL 2000	69.8
Others	28.1
S&P 500	2.1

Top 5 Winners (%)		%
VOR	vor biopharma inc	36.4 %
INVA	innoviva inc	14.5 %
LNTH	lantheus hldgs inc	13.4 %
AMRN	amarin corp plc	3.6 %
IRWD	ironwood pharmaceuticals inc	3.3 %

Top 5 Winners ($)		$
INVA	innoviva inc	8.2 M
IRWD	ironwood pharmaceuticals inc	1.8 M
LNTH	lantheus hldgs inc	1.6 M
AMRN	amarin corp plc	0.8 M
CYTK	cytokinetics inc	0.7 M

Top 5 Losers (%)		%
	biohaven ltd	-24.2 %
NBIX	neurocrine biosciences inc	-4.9 %

Top 5 Losers ($)		$
NBIX	neurocrine biosciences inc	-2.1 M
	biohaven ltd	-1.5 M

Sarissa Capital Management LP Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Sarissa Capital Management LP

Sarissa Capital Management LP has 9 stocks in it's portfolio. NBIX proved to be the most loss making stock for the portfolio. INVA was the most profitable stock for Sarissa Capital Management LP last quarter.

$157.64MTotal Value

9.00Positions

15 May, 2026Last Reported

Current holdings of Current Stock Holdings of Sarissa Capital Management LP, last reported on 15 May, 2026. Select a row with a linked ticker to view its historical trend.
Holdingsorted ascending	% Portfolio	Shares Held	$ Value	% Change
AMRN Amarin Corp Plc Amarin Corp PlcAMRN Sarissa Capital Management LP's holding in Amarin Corp Plc over time	15.35%	1,673,400	$24.20M 15.35%	unchanged 0 percentunchanged

CYTK Cytokinetics Inc Cytokinetics IncCYTK Sarissa Capital Management LP's holding in Cytokinetics Inc over time	9.56%	228,623	$15.07M 9.56%	decreased 42.32 percentreduced

INVA Innoviva Inc Innoviva IncINVA Sarissa Capital Management LP's holding in Innoviva Inc over time	31.5%	2,130,950	$49.65M 31.5%	decreased 24.33 percentreduced

IRWD Ironwood Pharmaceuticals Inc Ironwood Pharmaceuticals IncIRWD Sarissa Capital Management LP's holding in Ironwood Pharmaceuticals Inc over time	20.46%	9,188,640	$32.25M 20.46%	decreased 42.28 percentreduced

LNTH Lantheus Hldgs Inc Lantheus Hldgs IncLNTH Sarissa Capital Management LP's holding in Lantheus Hldgs Inc over time	8.03%	166,919	$12.66M 8.03%	decreased 8.01 percentreduced

NBIX Neurocrine Biosciences Inc Neurocrine Biosciences IncNBIX Sarissa Capital Management LP's holding in Neurocrine Biosciences Inc over time	9.74%	116,533	$15.35M 9.74%	decreased 61.56 percentreduced

REGN Regeneron Pharmaceuticals Regeneron PharmaceuticalsREGN Sarissa Capital Management LP's holding in Regeneron Pharmaceuticals over time	2.05%	4,190	$3.24M 2.05%	unchanged 0 percentunchanged

VOR Vor Biopharma Inc Vor Biopharma IncVOR Sarissa Capital Management LP's holding in Vor Biopharma Inc over time	0.29%	25,399	$453.1K 0.29%	unchanged 0 percentunchanged

Com Biohaven Ltd Biohaven Ltd Sarissa Capital Management LP's holding in Biohaven Ltd over time	3.02%	563,184	$4.76M 3.02%	increased 9.74 percentadded