Latest ACUTA CAPITAL PARTNERS, LLC Stock Portfolio
ACUTA CAPITAL PARTNERS, LLC Performance:
2025 Q4: 62.83%YTD: 117.97%2024: 23.91%
Performance for 2025 Q4 is 62.83%, and YTD is 117.97%, and 2024 is 23.91%.
About ACUTA CAPITAL PARTNERS, LLC and 13F Hedge Fund Stock Holdings
On 2026-02-17, the fund reported it's updated stock portfolio. In the 13F Holdings report, ACUTA CAPITAL PARTNERS, LLC reported an equity portfolio of $147.3 Millions as of 31 Dec, 2025.
The top stock holdings of ACUTA CAPITAL PARTNERS, LLC are TERN, PRAX, CDTX. The fund has invested 17.5% of it's portfolio in TERNS PHARMACEUTICALS INC and 16.6% of portfolio in PRAXIS PRECISION MEDICINES I.
The fund managers got completely rid off TOURMALINE BIO INC, ASCENDIS PHA-ADR (ASND) and KRYSTAL BIOTECH INC (KRYS) stocks. They significantly reduced their stock positions in CIDARA THERAPEUTICS INC (CDTX), DIANTHUS THERAPEUTICS INC and INSMED INC (INSM). ACUTA CAPITAL PARTNERS, LLC opened new stock positions in MINERVA NEUROSCIENCES (NERV), TANGO THERAPEUTICS INC (TNGX) and DESIGN THERAPEUTICS INC (DSGN). The fund showed a lot of confidence in some stocks as they added substantially to PRAXIS PRECISION MEDICINES I (PRAX), COMPASS THERAPEUTICS INC (CMPX) and TERNS PHARMACEUTICALS INC (TERN).
The top stock holdings of ACUTA CAPITAL PARTNERS, LLC are TERN, PRAX, CDTX. The fund has invested 17.5% of it's portfolio in TERNS PHARMACEUTICALS INC and 16.6% of portfolio in PRAXIS PRECISION MEDICINES I.
The fund managers got completely rid off TOURMALINE BIO INC, ASCENDIS PHA-ADR (ASND) and KRYSTAL BIOTECH INC (KRYS) stocks. They significantly reduced their stock positions in CIDARA THERAPEUTICS INC (CDTX), DIANTHUS THERAPEUTICS INC and INSMED INC (INSM). ACUTA CAPITAL PARTNERS, LLC opened new stock positions in MINERVA NEUROSCIENCES (NERV), TANGO THERAPEUTICS INC (TNGX) and DESIGN THERAPEUTICS INC (DSGN). The fund showed a lot of confidence in some stocks as they added substantially to PRAXIS PRECISION MEDICINES I (PRAX), COMPASS THERAPEUTICS INC (CMPX) and TERNS PHARMACEUTICALS INC (TERN).
ACUTA CAPITAL PARTNERS, LLC Annual Return Estimates Vs S&P 500
Our best estimate is that ACUTA CAPITAL PARTNERS, LLC made a return of 62.83% in the last quarter. In trailing 12 months, it's portfolio return was 117.97%.
- Performance
- S&P 500
New Buys
| Ticker | $ Bought |
|---|---|
| minerva neurosciences | 2,852,190 |
| tango therapeutics inc | 2,505,010 |
| design therapeutics inc | 1,415,500 |
| maze therapeutics inc | 828,600 |
| moonlake immunotherapeutics | 781,310 |
| sutro biopharma inc | 780,408 |
| pasithea therapeutics corp | 580,500 |
New stocks bought by ACUTA CAPITAL PARTNERS, LLC
Additions
| Ticker | % Inc. |
|---|---|
| praxis precision medicines i | 66.9 |
| compass therapeutics inc | 30.14 |
| terns pharmaceuticals inc | 26.71 |
| jazz pharmaceuticals plc | 15.51 |
Additions to existing portfolio by ACUTA CAPITAL PARTNERS, LLC
Reductions
| Ticker | % Reduced |
|---|---|
| cidara therapeutics inc | -37.01 |
| dianthus therapeutics inc | -33.17 |
| insmed inc | -32.94 |
| argen se - adr | -23.95 |
| ocular therapeutix inc | -9.63 |
| bright minds biosciences inc | -0.47 |
ACUTA CAPITAL PARTNERS, LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| tourmaline bio inc | -12,840,000 |
| cogent biosciences inc | -1,477,740 |
| fulcrum therapeutics inc | -525,697 |
| krystal biotech inc | -1,866,450 |
| ascendis pha-adr | -1,946,750 |
ACUTA CAPITAL PARTNERS, LLC got rid off the above stocks
Sector Distribution
ACUTA CAPITAL PARTNERS, LLC has about 87.6% of it's holdings in Healthcare sector.
- Healthcare
- Others
| Sector | % |
|---|---|
| Healthcare | 87.6 |
| Others | 12.4 |
Market Cap. Distribution
ACUTA CAPITAL PARTNERS, LLC has about 13.2% of it's portfolio invested in the large-cap and mega-cap stocks.
- MID-CAP
- SMALL-CAP
- UNALLOCATED
- LARGE-CAP
- MEGA-CAP
- MICRO-CAP
- NANO-CAP
| Category | % |
|---|---|
| MID-CAP | 47.5 |
| SMALL-CAP | 21.1 |
| UNALLOCATED | 12.4 |
| LARGE-CAP | 7.6 |
| MEGA-CAP | 5.6 |
| MICRO-CAP | 3.5 |
| NANO-CAP | 2.3 |
Stocks belong to which Index?
About 46.6% of the stocks held by ACUTA CAPITAL PARTNERS, LLC either belong to S&P 500 or RUSSELL 2000 index.
- Others
- RUSSELL 2000
| Index | % |
|---|---|
| Others | 53.4 |
| RUSSELL 2000 | 46.6 |
ACUTA CAPITAL PARTNERS, LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of ACUTA CAPITAL PARTNERS, LLC
ACUTA CAPITAL PARTNERS, LLC has 30 stocks in it's portfolio. About 79.4% of the portfolio is in top 10 stocks. AMLX proved to be the most loss making stock for the portfolio. TERN was the most profitable stock for ACUTA CAPITAL PARTNERS, LLC last quarter.
Last Reported on: 17 Feb, 2026| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| AADI | whitehawk therapeutics inc | 5.60 | 3,410,400 | 8,253,170 | unchanged | 0.00 | ||
| AMLX | amylyx pharmaceuticals inc | 2.73 | 333,258 | 4,025,760 | unchanged | 0.00 | ||
| ARGX | argen se - adr | 2.77 | 4,851 | 4,079,450 | reduced | -23.95 | ||
| ASND | ascendis pha-adr | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| CDTX | cidara therapeutics inc | 13.37 | 89,145 | 19,691,200 | reduced | -37.01 | ||
| CMPX | compass therapeutics inc | 3.99 | 1,093,300 | 5,871,020 | added | 30.14 | ||
| COGT | cogent biosciences inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| DRUG | bright minds biosciences inc | 4.48 | 84,477 | 6,592,580 | reduced | -0.47 | ||
| DSGN | design therapeutics inc | 0.96 | 150,906 | 1,415,500 | new | |||
| FULC | fulcrum therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| INSM | insmed inc | 3.06 | 25,878 | 4,503,810 | reduced | -32.94 | ||
| JAZZ | jazz pharmaceuticals plc | 3.35 | 29,008 | 4,931,360 | added | 15.51 | ||
| KRYS | krystal biotech inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| KTTA | pasithea therapeutics corp | 0.39 | 450,000 | 580,500 | new | |||
| MLTX | moonlake immunotherapeutics | 0.53 | 59,280 | 781,310 | new | |||
| NERV | minerva neurosciences | 1.94 | 709,500 | 2,852,190 | new | |||
| NUVB | nuvation bio inc -cw27 | 0.02 | 90,832 | 29,975 | unchanged | 0.00 | ||
| OCUL | ocular therapeutix inc | 8.68 | 1,053,000 | 12,783,400 | reduced | -9.63 | ||
| PRAX | praxis precision medicines i | 16.62 | 83,036 | 24,474,000 | added | 66.9 | ||
| RVMD | revolution medicines inc | 0.46 | 8,411 | 669,936 | unchanged | 0.00 | ||