Latest EcoR1 Capital, LLC Stock Portfolio
$3.85Billion
Equity Portfolio Value
Last Reported on: 14 Feb, 2024
About EcoR1 Capital, LLC and it’s 13F Hedge Fund Stock Holdings
EcoR1 Capital, LLC is a hedge fund based in San Francisco, CA. On 29-Mar-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $4.7 Billions. In it's latest 13F Holdings report, EcoR1 Capital, LLC reported an equity portfolio of $3 Billions as of 30 Sep, 2023.
The top stock holdings of EcoR1 Capital, LLC are PRTA, APLS, MRTX. The fund has invested 18.9% of it's portfolio in PROTHENA CORP PLC and 14% of portfolio in APELLIS PHARMACEUTICALS INC.
The fund managers got completely rid off SAREPTA THERAPEUTICS INC (SRPT), BLUEPRINT MEDICINES CORP (BPMC) and DYNE THERAPEUTICS INC (DYN) stocks. They significantly reduced their stock positions in MORPHIC HLDG INC (MORF), REVOLUTION MEDICINES INC (RVMD) and TEMPEST THERAPEUTICS INC (TPST). EcoR1 Capital, LLC opened new stock positions in MIRATI THERAPEUTICS INC (MRTX), NEUMORA THERAPEUTICS INC. and MERSANA THERAPEUTICS INC (MRSN). The fund showed a lot of confidence in some stocks as they added substantially to TANGO THERAPEUTICS INC (TNGX), APELLIS PHARMACEUTICALS INC (APLS) and THIRD HARMONIC BIO INC (THRD).
The top stock holdings of EcoR1 Capital, LLC are PRTA, APLS, MRTX. The fund has invested 18.9% of it's portfolio in PROTHENA CORP PLC and 14% of portfolio in APELLIS PHARMACEUTICALS INC.
The fund managers got completely rid off SAREPTA THERAPEUTICS INC (SRPT), BLUEPRINT MEDICINES CORP (BPMC) and DYNE THERAPEUTICS INC (DYN) stocks. They significantly reduced their stock positions in MORPHIC HLDG INC (MORF), REVOLUTION MEDICINES INC (RVMD) and TEMPEST THERAPEUTICS INC (TPST). EcoR1 Capital, LLC opened new stock positions in MIRATI THERAPEUTICS INC (MRTX), NEUMORA THERAPEUTICS INC. and MERSANA THERAPEUTICS INC (MRSN). The fund showed a lot of confidence in some stocks as they added substantially to TANGO THERAPEUTICS INC (TNGX), APELLIS PHARMACEUTICALS INC (APLS) and THIRD HARMONIC BIO INC (THRD).
New Buys
| Ticker | $ Bought |
|---|---|
| ARGENX SE | 114,508,000 |
| SAREPTA THERAPEUTICS INC | 80,317,200 |
| IMMUNOME INC | 41,509,700 |
| PHARVARIS N V | 25,245,000 |
| NEUROGENE INC | 24,638,600 |
| VERVE THERAPEUTICS INC | 17,425,000 |
| ITEOS THERAPEUTICS INC | 12,209,500 |
| ATARA BIOTHERAPEUTICS INC | 5,162,380 |
New stocks bought by EcoR1 Capital, LLC
Additions
| Ticker | % Inc. |
|---|---|
| SPYRE THERAPEUTICS INC | 343 |
| JAZZ PHARMACEUTICALS PLC | 175 |
| ALIGOS THERAPEUTICS INC | 61.83 |
| TANGO THERAPEUTICS INC | 52.85 |
| CRINETICS PHARMACEUTICALS IN | 31.51 |
| MIRATI THERAPEUTICS INC | 28.68 |
| ARVINAS INC | 23.04 |
| THIRD HARMONIC BIO INC | 6.71 |
Additions to existing portfolio by EcoR1 Capital, LLC
Reductions
| Ticker | % Reduced |
|---|---|
| REVOLUTION MEDICINES INC | -97.62 |
| MORPHIC HLDG INC | -85.73 |
| PHATHOM PHARMACEUTICALS INC | -71.65 |
| NGM BIOPHARMACEUTICALS INC | -62.93 |
EcoR1 Capital, LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| ALLOGENE THERAPEUTICS INC | -14,227,600 |
| RELAY THERAPEUTICS INC | -35,017,800 |
| SPRINGWORKS THERAPEUTICS INC | -80,000,000 |
| ACELYRIN INC | -14,260,400 |
| PRELUDE THERAPEUTICS INC | -3,576,530 |
| DECIPHERA PHARMACEUTICALS IN | -12,631,000 |
| TEMPEST THERAPEUTICS INC | -283,676 |
| PRIME MEDICINE INC | -5,724,000 |
EcoR1 Capital, LLC got rid off the above stocks
Current Stock Holdings of EcoR1 Capital, LLC
Last Reported on: 14 Feb, 2024| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options |
|---|---|---|---|---|---|---|---|
| ACAD | ACADIA PHARMACEUTICALS INC | 4.87 | 5,991,480 | 187,593,000 | UNCHANGED | 0.00 | |
| AGLE | SPYRE THERAPEUTICS INC | 0.50 | 887,076 | 19,089,900 | ADDED | 343 | |
| ALEC | ALECTOR INC | 0.84 | 4,056,550 | 32,371,300 | UNCHANGED | 0.00 | |
| ALGS | ALIGOS THERAPEUTICS INC | 0.11 | 6,389,470 | 4,242,610 | ADDED | 61.83 | |
| ALLK | ALLAKOS INC | 0.05 | 748,900 | 2,044,500 | UNCHANGED | 0.00 | |
| ALLO | ALLOGENE THERAPEUTICS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| ANAB | ANAPTYSBIO INC | 4.18 | 7,521,020 | 161,100,000 | UNCHANGED | 0.00 | |
| APLS | APELLIS PHARMACEUTICALS INC | 17.36 | 11,173,100 | 668,820,000 | ADDED | 2.51 | |
| ARGX | ARGENX SE | 2.97 | 300,997 | 114,508,000 | NEW | ||
| ARVN | ARVINAS INC | 7.19 | 6,726,490 | 276,862,000 | ADDED | 23.04 | |
| ATRA | ATARA BIOTHERAPEUTICS INC | 0.13 | 10,067,000 | 5,162,380 | NEW | ||
| AVIR | ATEA PHARMACEUTICALS INC | 0.55 | 6,995,860 | 21,337,400 | UNCHANGED | 0.00 | |
| CMAX | CAREMAX INC | 0.00 | 100,000 | 49,820 | UNCHANGED | 0.00 | |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 1.16 | 5,618,780 | 44,725,500 | UNCHANGED | 0.00 | |
| CRNX | CRINETICS PHARMACEUTICALS IN | 1.86 | 2,012,520 | 71,605,400 | ADDED | 31.51 | |
| DCPH | DECIPHERA PHARMACEUTICALS IN | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| EWTX | EDGEWISE THERAPEUTICS INC | 0.99 | 3,493,190 | 38,215,500 | UNCHANGED | 0.00 | |
| GBIO | GENERATION BIO CO | 0.09 | 2,046,870 | 3,377,330 | UNCHANGED | 0.00 | |
| GLPG | GALAPAGOS NV | 6.08 | 5,756,270 | 233,992,000 | UNCHANGED | 0.00 | |
| GOSS | GOSSAMER BIO INC | 0.22 | 9,195,400 | 8,390,810 | UNCHANGED | 0.00 | |
| GRPH | GRAPHITE BIO INC | 0.58 | 8,538,450 | 22,370,700 | UNCHANGED | 0.00 | |
| HOOK | HOOKIPA PHARMA INC | 0.10 | 4,595,020 | 3,721,970 | UNCHANGED | 0.00 | |
| IMNM | IMMUNOME INC | 1.08 | 3,879,420 | 41,509,700 | NEW | ||
| ITOS | ITEOS THERAPEUTICS INC | 0.32 | 1,115,020 | 12,209,500 | NEW | ||
| JAZZ | JAZZ PHARMACEUTICALS PLC | 3.24 | 1,013,950 | 124,716,000 | ADDED | 175 | |
| KURA | KURA ONCOLOGY INC | 2.17 | 5,806,870 | 83,502,800 | UNCHANGED | 0.00 | |
| MORF | MORPHIC HLDG INC | 0.16 | 211,262 | 6,101,250 | REDUCED | -85.73 | |
| MRSN | MERSANA THERAPEUTICS INC | 1.17 | 19,364,700 | 44,926,100 | UNCHANGED | 0.00 | |
| MRTX | MIRATI THERAPEUTICS INC | 11.28 | 7,396,980 | 434,573,000 | ADDED | 28.68 | |
| NAMS | NEWAMSTERDAM PHARMA COMPANY | 0.02 | 66,665 | 744,648 | UNCHANGED | 0.00 | |
| NGM | NGM BIOPHARMACEUTICALS INC | 0.05 | 2,385,870 | 2,049,460 | REDUCED | -62.93 | |
| NUVB | NUVATION BIO INC | 0.75 | 19,209,600 | 29,006,600 | UNCHANGED | 0.00 | |
| NUVB | NUVATION BIO INC | 0.04 | 963,333 | 1,454,630 | UNCHANGED | 0.00 | |
| ORIC | ORIC PHARMACEUTICALS INC | 0.82 | 3,418,070 | 31,446,200 | UNCHANGED | 0.00 | |
| OVID | OVID THERAPEUTICS INC | 0.51 | 6,117,400 | 19,698,000 | UNCHANGED | 0.00 | |
| PHAT | PHATHOM PHARMACEUTICALS INC | 0.05 | 198,480 | 1,812,120 | REDUCED | -71.65 | |
| PHVS | PHARVARIS N V | 0.66 | 900,000 | 25,245,000 | NEW | ||
| PMVP | PMV PHARMACEUTICALS INC | 0.05 | 566,879 | 1,757,320 | NEW | ||
| PRLD | PRELUDE THERAPEUTICS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| PRQR | PROQR THRAPEUTICS N V | 0.15 | 2,980,020 | 5,900,430 | UNCHANGED | 0.00 | |
| PRTA | PROTHENA CORP PLC | 10.93 | 11,584,300 | 420,973,000 | UNCHANGED | 0.00 | |
| RLAY | RELAY THERAPEUTICS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| RVMD | REVOLUTION MEDICINES INC | 0.10 | 132,579 | 3,802,370 | REDUCED | -97.62 | |
| SRPT | SAREPTA THERAPEUTICS INC | 2.08 | 832,907 | 80,317,200 | NEW | ||
| SRZN | SURROZEN INC | 0.02 | 66,665 | 626,651 | UNCHANGED | 0.00 | |
| SWTX | SPRINGWORKS THERAPEUTICS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| TCRX | TSCAN THERAPEUTICS INC | 0.76 | 5,000,000 | 29,150,000 | UNCHANGED | 0.00 | |
| THRD | THIRD HARMONIC BIO INC | 0.91 | 3,182,440 | 34,911,400 | ADDED | 6.71 | |
| TNGX | TANGO THERAPEUTICS INC | 3.43 | 13,330,700 | 131,974,000 | ADDED | 52.85 | |
| TPST | TEMPEST THERAPEUTICS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| TYRA | TYRA BIOSCIENCES INC | 0.05 | 137,014 | 1,897,640 | NEW | ||
| VERV | VERVE THERAPEUTICS INC | 0.45 | 1,250,000 | 17,425,000 | NEW | ||
| VYGR | VOYAGER THERAPEUTICS INC | 0.84 | 3,851,510 | 32,506,700 | UNCHANGED | 0.00 | |
| XNCR | XENCOR INC | 2.91 | 5,282,520 | 112,148,000 | UNCHANGED | 0.00 | |
| ZYMEWORKS INC | 3.62 | 13,437,500 | 139,615,000 | UNCHANGED | 0.00 | ||
| NEUMORA THERAPEUTICS INC. | 0.92 | 2,071,450 | 35,318,200 | UNCHANGED | 0.00 | ||
| NEUROGENE INC | 0.64 | 1,271,340 | 24,638,600 | NEW | |||
| PRIME MEDICINE INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | ||
| ACELYRIN INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 |