Latest Omega Fund Management, LLC Stock Portfolio
Omega Fund Management, LLC Performance:
2025 Q3: 34.46%YTD: -2.83%2024: -3.47%
Performance for 2025 Q3 is 34.46%, and YTD is -2.83%, and 2024 is -3.47%.
About Omega Fund Management, LLC and 13F Hedge Fund Stock Holdings
Omega Fund Management, LLC is a hedge fund based in BOSTON, MA. On 12-Jun-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $1.4 Billions. In it's latest 13F Holdings report, Omega Fund Management, LLC reported an equity portfolio of $222.4 Millions as of 30 Sep, 2025.
The top stock holdings of Omega Fund Management, LLC are , , . The fund has invested 17.6% of it's portfolio in KESTRA MED TECHNOLOGIES LTD and 17.2% of portfolio in BETA BIONICS INC.
The fund managers got completely rid off LEXEO THERAPEUTICS, IKENA ONCOLOGY (IKNA) and IMMUNIC INC. (IMUX) stocks. They significantly reduced their stock positions in REPLIMUNE GROUP (REPL), ENGENE HOLDINGS INC. and NUVATION BIO (NUVB). Omega Fund Management, LLC opened new stock positions in BRIDGEBIO ONCOLOGY THERAPEUTICS INC. and IMAGENEBIO, INC. (IKNA).
The top stock holdings of Omega Fund Management, LLC are , , . The fund has invested 17.6% of it's portfolio in KESTRA MED TECHNOLOGIES LTD and 17.2% of portfolio in BETA BIONICS INC.
The fund managers got completely rid off LEXEO THERAPEUTICS, IKENA ONCOLOGY (IKNA) and IMMUNIC INC. (IMUX) stocks. They significantly reduced their stock positions in REPLIMUNE GROUP (REPL), ENGENE HOLDINGS INC. and NUVATION BIO (NUVB). Omega Fund Management, LLC opened new stock positions in BRIDGEBIO ONCOLOGY THERAPEUTICS INC. and IMAGENEBIO, INC. (IKNA).
Omega Fund Management, LLC Annual Return Estimates Vs S&P 500
Our best estimate is that Omega Fund Management, LLC made a return of 34.46% in the last quarter. In trailing 12 months, it's portfolio return was -13.32%.
New Buys
| Ticker | $ Bought |
|---|---|
| bridgebio oncology therapeutics inc. | 38,094,300 |
| imagenebio, inc. | 3,711,190 |
New stocks bought by Omega Fund Management, LLC
Additions
Reductions
| Ticker | % Reduced |
|---|---|
| replimune group | -87.41 |
| engene holdings inc. | -72.1 |
| upstream bio inc. | -33.39 |
| nuvation bio | -20.03 |
| beta bionics inc. | -3.43 |
Omega Fund Management, LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| immunic inc. | -1,248,140 |
| lexeo therapeutics | -4,762,240 |
| ikena oncology | -3,013,820 |
Omega Fund Management, LLC got rid off the above stocks
Sector Distribution
Omega Fund Management, LLC has about 81.8% of it's holdings in Others sector.
| Sector | % |
|---|---|
| Others | 81.8 |
| Healthcare | 18.2 |
Market Cap. Distribution
Omega Fund Management, LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.
| Category | % |
|---|---|
| UNALLOCATED | 81.8 |
| SMALL-CAP | 16.5 |
| MICRO-CAP | 1.7 |
Stocks belong to which Index?
About 18.2% of the stocks held by Omega Fund Management, LLC either belong to S&P 500 or RUSSELL 2000 index.
| Index | % |
|---|---|
| Others | 81.8 |
| RUSSELL 2000 | 18.2 |
Omega Fund Management, LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Omega Fund Management, LLC
Omega Fund Management, LLC has 12 stocks in it's portfolio. REPL proved to be the most loss making stock for the portfolio. NUVB was the most profitable stock for Omega Fund Management, LLC last quarter.
Last Reported on: 14 Nov, 2025| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| IKNA | imagenebio, inc. | 1.67 | 455,361 | 3,711,190 | new | |||
| IKNA | ikena oncology | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| IMUX | immunic inc. | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| NUVB | nuvation bio | 14.69 | 8,831,090 | 32,675,000 | reduced | -20.03 | ||
| REPL | replimune group | 0.47 | 248,672 | 1,041,940 | reduced | -87.41 | ||
| SANA | sana biotechnology, inc. | 1.35 | 843,750 | 2,995,310 | unchanged | 0.00 | ||
| kestra med technologies ltd | 17.59 | 1,645,890 | 39,106,400 | unchanged | 0.00 | |||
| beta bionics inc. | 17.16 | 1,920,120 | 38,152,900 | reduced | -3.43 | |||
| bridgebio oncology therapeutics inc. | 17.13 | 3,289,660 | 38,094,300 | new | ||||
| bicara therapeutics inc. | 15.65 | 2,204,650 | 34,811,400 | unchanged | 0.00 | |||
| upstream bio inc. | 11.47 | 1,356,290 | 25,511,900 | reduced | -33.39 | |||
| engene holdings inc. | 1.62 | 526,357 | 3,595,020 | unchanged | 0.00 | |||
| alumis inc. | 1.17 | 653,223 | 2,606,360 | unchanged | 0.00 | |||
| engene holdings inc. | 0.03 | 89,702 | 63,438 | reduced | -72.1 | |||
| lexeo therapeutics | 0.00 | 0.00 | 0.00 | sold off | -100 | |||