Latest Omega Fund Management, LLC Stock Portfolio
$185Million | No. of Holdings #10
Omega Fund Management, LLC Performance
2026 Q2+23.88%
YTD-13.23%
2025+35.56%
About Omega Fund Management, LLC and 13F Hedge Fund Stock Holdings
Omega Fund Management, LLC is a hedge fund based in Boston, MA. On 2026-08-14, the fund reported it's updated stock portfolio. In the 13F Holdings report, Omega Fund Management, LLC reported an equity portfolio of $185.7 Millions as of 30 Jun, 2026. <br><br> The top stock holdings of Omega Fund Management, LLC are , NUVB, . The fund has invested 29.1% of it's portfolio in BICARA THERAPEUTICS INC. and 24.7% of portfolio in NUVATION BIO INC. <br><br> The fund managers got completely rid off REPLIMUNE GROUP (REPL) stocks. They significantly reduced their stock positions in BICARA THERAPEUTICS INC.. Omega Fund Management, LLC opened new stock positions in ODYSSEY THERAPEUTICS INC..
Omega Fund Management, LLC Equity Portfolio Value
Last Reported on: 14 Aug, 2026
$185Million
as of Aug 14, 2026Omega Fund Management, LLC Annual Return Estimates Vs S&P 500
Our best estimate is that Omega Fund Management, LLC made a return of 23.88% in the last quarter. In trailing 12 months, it's portfolio return was 62.76%.
- Performance
- S&P 500
New Buys
| Ticker | $ Bought |
|---|---|
| odyssey therapeutics inc. | 54,128 |
New stocks bought by Omega Fund Management, LLC
Additions
No additions were made to existing positions by Omega Fund Management, LLC
Reductions
| Ticker | % Reduced |
|---|---|
| bicara therapeutics inc. | -23.83 |
Omega Fund Management, LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| replimune group | -1,909,800 |
Omega Fund Management, LLC got rid off the above stocks
Sector Distribution
Omega Fund Management, LLC has about 72.2% of it's holdings in Others sector.
- Others
- Healthcare
| Sector | % |
|---|---|
| Others | 72.2 |
| Healthcare | 27.8 |
Market Cap. Distribution
Omega Fund Management, LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.
- UNALLOCATED
- MID-CAP
- SMALL-CAP
- MICRO-CAP
| Category | % |
|---|---|
| UNALLOCATED | 72.2 |
| MID-CAP | 24.7 |
| SMALL-CAP | 1.6 |
| MICRO-CAP | 1.4 |
Stocks belong to which Index?
About 27.8% of the stocks held by Omega Fund Management, LLC either belong to S&P 500 or RUSSELL 2000 index.
- Others
- RUSSELL 2000
| Index | % |
|---|---|
| Others | 72.2 |
| RUSSELL 2000 | 27.8 |
| Top 5 Winners (%) | % | |
|---|---|---|
beta bionics inc. | 56.4 % | |
bicara therapeutics inc. | 43.4 % | |
| NUVB | nuvation bio inc. | 32.4 % |
alumis inc. | 27.7 % | |
kestra med technologies ltd | 27.6 % | |
| Top 5 Winners ($) | $ | |
|---|---|---|
bicara therapeutics inc. | 20.7 M | |
| NUVB | nuvation bio inc. | 11.2 M |
beta bionics inc. | 7.4 M | |
kestra med technologies ltd | 5.6 M | |
alumis inc. | 1.5 M | |
| Top 5 Losers (%) | % | |
|---|---|---|
engene holdings inc. | -74.6 % | |
bridgebio oncology therapeutics inc. | -14.9 % | |
| Top 5 Losers ($) | $ | |
|---|---|---|
engene holdings inc. | -4.5 M | |
bridgebio oncology therapeutics inc. | -4.4 M | |
Omega Fund Management, LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Omega Fund Management, LLC
Omega Fund Management, LLC has 10 stocks in it's portfolio. proved to be the most loss making stock for the portfolio. was the most profitable stock for Omega Fund Management, LLC last quarter.
$185.69MTotal Value
11.00Positions
14 Aug, 2026Last Reported
| Expand | Holdingsorted ascending | % Portfolio | Shares Held | $ Value | % Change |
|---|---|---|---|---|---|
 Imagenebio, Inc. Imagenebio, Inc.IKNA Omega Fund Management, LLC's holding in Imagenebio, Inc. over time | 1.45% | 455,361 | $2.69M 1.45% | 0%unchanged 0 percentunchanged | |
 Nuvation Bio Inc. Omega Fund Management, LLC's holding in Nuvation Bio Inc. over time | 24.72% | 8,081,090 | $45.90M 24.72% | 0%unchanged 0 percentunchanged | |
 Replimune Group Replimune GroupREPL Omega Fund Management, LLC's holding in Replimune Group over time | 0% | 0.00 | $0.00 0% | 100%decreased 100 percentsold off | |
 Sana Biotechnology, Inc. Omega Fund Management, LLC's holding in Sana Biotechnology, Inc. over time | 1.59% | 843,750 | $2.94M 1.59% | 0%unchanged 0 percentunchanged | |
Common Stock Bicara Therapeutics Inc.Bicara Therapeutics Inc. | 29.14% | 1,822,150 | $54.10M 29.14% | 23.83%decreased 23.83 percentreduced | |
Common Stock Kestra Med Technologies LtdKestra Med Technologies Ltd | 14% | 1,022,150 | $26.00M 14% | 0%unchanged 0 percentunchanged | |
Common Stock Bridgebio Oncology Therapeutics Inc.Bridgebio Oncology Therapeutics Inc. | 13.5% | 3,289,660 | $25.07M 13.5% | 0%unchanged 0 percentunchanged | |
Common Stock Beta Bionics Inc.Beta Bionics Inc. | 11.11% | 1,316,180 | $20.62M 11.11% | 0%unchanged 0 percentunchanged | |
Common Stock Alumis Inc.Alumis Inc. | 3.66% | 241,255 | $6.79M 3.66% | 0%unchanged 0 percentunchanged | |
Common Stock Engene Holdings Inc.Engene Holdings Inc. | 0.82% | 876,357 | $1.52M 0.82% | 0%unchanged 0 percentunchanged | |
Common Stock Odyssey Therapeutics Inc.Odyssey Therapeutics Inc. | 0.03% | 2,893 | $54.1K 0.03% | Newnew position | |