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Latest Foresite Capital Management IV, LLC Stock Portfolio

$237Million– No. of Holdings #8

Foresite Capital Management IV, LLC Performance:
2026 Q1: -1.21%YTD: -1.21%2025: 58.24%
Performance for 2026 Q1 is -1.21%, and YTD is -1.21%, and 2025 is 58.24%.

About Foresite Capital Management IV, LLC and 13F Hedge Fund Stock Holdings

On 2026-05-15, the fund reported it's updated stock portfolio. In the 13F Holdings report, Foresite Capital Management IV, LLC reported an equity portfolio of $237.1 Millions as of 31 Mar, 2026.

The top stock holdings of Foresite Capital Management IV, LLC are PHVS, CYTK, . The fund has invested 56.9% of it's portfolio in PHARVARIS N.V. and 14% of portfolio in CYTOKINETICS INC.

They significantly reduced their stock positions in MAZE THERAPEUTICS, INC.. Foresite Capital Management IV, LLC opened new stock positions in EIKON THERAPEUTICS, INC.. The fund showed a lot of confidence in some stocks as they added substantially to CYTOKINETICS INC (CYTK).
Foresite Capital Management IV, LLC Equity Portfolio Value
Last Reported on: 15 May, 2026

Foresite Capital Management IV, LLC Annual Return Estimates Vs S&P 500

Our best estimate is that Foresite Capital Management IV, LLC made a return of -1.21% in the last quarter. In trailing 12 months, it's portfolio return was 84.7%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
eikon therapeutics, inc.20,564,200
New stocks bought by Foresite Capital Management IV, LLC

Additions

Ticker% Inc.
cytokinetics inc9.82
Additions to existing portfolio by Foresite Capital Management IV, LLC

Reductions

Ticker% Reduced
maze therapeutics, inc.-69.98
Foresite Capital Management IV, LLC reduced stake in above stock

Sold off

None of the stocks were completely sold off by Foresite Capital Management IV, LLC

Sector Distribution

Foresite Capital Management IV, LLC has about 67.6% of it's holdings in Others sector.

  • Others
  • Healthcare
Sector%
Others67.6
Healthcare32.4

Market Cap. Distribution

Foresite Capital Management IV, LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.

  • UNALLOCATED
  • MID-CAP
  • SMALL-CAP
  • MICRO-CAP
Category%
UNALLOCATED67.6
MID-CAP17.9
SMALL-CAP11
MICRO-CAP3.5

Stocks belong to which Index?

About 28.5% of the stocks held by Foresite Capital Management IV, LLC either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • RUSSELL 2000
Index%
Others71.5
RUSSELL 200028.5
Top 5 Winners (%)%
ALEC
alector, inc.
37.8 %
XENE
xenon pharmaceuticals inc.
29.7 %
RLAY
relay therapeutics, inc.
17.6 %
CYTK
cytokinetics inc
3.6 %
PHVS
pharvaris n.v.
1.8 %
Top 5 Winners ($)$
PHVS
pharvaris n.v.
2.4 M
ALEC
alector, inc.
2.3 M
XENE
xenon pharmaceuticals inc.
2.1 M
RLAY
relay therapeutics, inc.
1.5 M
CYTK
cytokinetics inc
1.1 M
Top 5 Losers (%)%
LYEL
lyell immunopharma, inc.
-34.8 %
maze therapeutics, inc.
-18.2 %
Top 5 Losers ($)$
LYEL
lyell immunopharma, inc.
-8.6 M
maze therapeutics, inc.
-3.9 M

Foresite Capital Management IV, LLC Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Foresite Capital Management IV, LLC

Foresite Capital Management IV, LLC has 8 stocks in it's portfolio. LYEL proved to be the most loss making stock for the portfolio. PHVS was the most profitable stock for Foresite Capital Management IV, LLC last quarter.

Last Reported on: 15 May, 2026
TickerNamesorted ascending% PortfolioShares Held$ ValueType% ChangeOptions