Latest Foresite Capital Management IV, LLC Stock Portfolio

Foresite Capital Management IV, LLC Performance:
2025 Q2: 6.05%YTD: 0.73%2024: -21.32%

Performance for 2025 Q2 is 6.05%, and YTD is 0.73%, and 2024 is -21.32%.

About Foresite Capital Management IV, LLC and 13F Hedge Fund Stock Holdings

In it's latest 13F Holdings report, Foresite Capital Management IV, LLC reported an equity portfolio of $123.8 Millions as of 30 Jun, 2025.

The top stock holdings of Foresite Capital Management IV, LLC are PHVS, , LYEL. The fund has invested 62.7% of it's portfolio in PHARVARIS N.V. and 20.9% of portfolio in MAZE THERAPEUTICS INC.

The fund managers got completely rid off LYELL IMMUNOPHARMA, INC. (LYEL) stocks. They significantly reduced their stock positions in KURA ONCOLOGY, INC. (KURA). Foresite Capital Management IV, LLC opened new stock positions in LYELL IMMUNOPHARMA, INC. (LYEL) and XENON PHARMACEUTICALS INC (XENE).

Foresite Capital Management IV, LLC Annual Return Estimates Vs S&P 500

Our best estimate is that Foresite Capital Management IV, LLC made a return of 6.05% in the last quarter. In trailing 12 months, it's portfolio return was -22.24%.
2019202020212022202320242025−40−200204060Performance (%)PerformanceS&P 500

New Buys


New stocks bought by Foresite Capital Management IV, LLC

Additions

No additions were made to existing positions by Foresite Capital Management IV, LLC

Reductions

Ticker% Reduced
kura oncology, inc.-26.53

Foresite Capital Management IV, LLC reduced stake in above stock

Sold off

Ticker$ Sold
lyell immunopharma, inc.-8,612,300

Foresite Capital Management IV, LLC got rid off the above stocks

Sector Distribution

Foresite Capital Management IV, LLC has about 83.6% of it's holdings in Others sector.

84%16%
Sector%
Others83.6
Healthcare16.4

Market Cap. Distribution

Foresite Capital Management IV, LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.

84%12%
Category%
UNALLOCATED83.6
SMALL-CAP12.3
MID-CAP4

Stocks belong to which Index?

About 12.3% of the stocks held by Foresite Capital Management IV, LLC either belong to S&P 500 or RUSSELL 2000 index.

88%12%
Index%
Others87.7
RUSSELL 200012.3
Top 5 Winners (%)%
LYEL
lyell immunopharma, inc.
1821.7 %
RLAY
relay therapeutics inc.
32.1 %
Top 5 Winners ($)$
LYEL
lyell immunopharma, inc.
6.7 M
RLAY
relay therapeutics inc.
0.8 M
Top 5 Losers (%)%
KURA
kura oncology, inc.
-12.1 %
XENE
xenon pharmaceuticals inc
-2.4 %
Top 5 Losers ($)$
KURA
kura oncology, inc.
-0.9 M
XENE
xenon pharmaceuticals inc
-0.1 M

Foresite Capital Management IV, LLC Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

PHVSLYELXENEKURARLAY

Current Stock Holdings of Foresite Capital Management IV, LLC

Foresite Capital Management IV, LLC has 6 stocks in it's portfolio. KURA proved to be the most loss making stock for the portfolio. LYEL was the most profitable stock for Foresite Capital Management IV, LLC last quarter.

Last Reported on: 12 Aug, 2025
TickerNamesorted descending% PortfolioShares Held$ ValueType% ChangeOptions

Historical Trend of PHARVARIS N.V. Position Held By Foresite Capital Management IV, LLC

What % of Portfolio is PHVS?:

Number of PHVS shares held:

Change in No. of Shares Held: