Latest Samsara BioCapital, LLC Stock Portfolio
Samsara BioCapital, LLC Performance:
2025 Q3: 55.06%YTD: 6.03%2024: 3.02%
Performance for 2025 Q3 is 55.06%, and YTD is 6.03%, and 2024 is 3.02%.
About Samsara BioCapital, LLC and 13F Hedge Fund Stock Holdings
SAMSARA BIOCAPITAL, LLC is a hedge fund based in PALO ALTO, CA. On 26-Apr-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $1.4 Billions. In it's latest 13F Holdings report, SAMSARA BIOCAPITAL, LLC reported an equity portfolio of $765.9 Millions as of 30 Sep, 2025.
The top stock holdings of SAMSARA BIOCAPITAL, LLC are , SRRK, . The fund has invested 31% of it's portfolio in MINERALYS THERAPEUTICS INC and 27.3% of portfolio in SCHOLAR ROCK HLDG CORP.
The fund managers got completely rid off CARGO THERAPEUTICS INC, TANGO THERAPEUTICS INC (TNGX) and HILLEVAX INC (HLVX) stocks. They significantly reduced their stock positions in AURA BIOSCIENCES INC (AURA), RHYTHM PHARMACEUTICALS INC (RYTM) and PALVELLA THERAPEUTICS INC NE. SAMSARA BIOCAPITAL, LLC opened new stock positions in AQUESTIVE THERAPEUTICS INC (AQST) and ABIVAX SA. The fund showed a lot of confidence in some stocks as they added substantially to VTV THERAPEUTICS INC (VTVT) and MINERALYS THERAPEUTICS INC.
The top stock holdings of SAMSARA BIOCAPITAL, LLC are , SRRK, . The fund has invested 31% of it's portfolio in MINERALYS THERAPEUTICS INC and 27.3% of portfolio in SCHOLAR ROCK HLDG CORP.
The fund managers got completely rid off CARGO THERAPEUTICS INC, TANGO THERAPEUTICS INC (TNGX) and HILLEVAX INC (HLVX) stocks. They significantly reduced their stock positions in AURA BIOSCIENCES INC (AURA), RHYTHM PHARMACEUTICALS INC (RYTM) and PALVELLA THERAPEUTICS INC NE. SAMSARA BIOCAPITAL, LLC opened new stock positions in AQUESTIVE THERAPEUTICS INC (AQST) and ABIVAX SA. The fund showed a lot of confidence in some stocks as they added substantially to VTV THERAPEUTICS INC (VTVT) and MINERALYS THERAPEUTICS INC.
Samsara BioCapital, LLC Annual Return Estimates Vs S&P 500
Our best estimate is that SAMSARA BIOCAPITAL, LLC made a return of 55.06% in the last quarter. In trailing 12 months, it's portfolio return was 27.94%.
New Buys
| Ticker | $ Bought |
|---|---|
| aquestive therapeutics inc | 13,975,000 |
| abivax sa | 6,405,030 |
New stocks bought by Samsara BioCapital, LLC
Additions
| Ticker | % Inc. |
|---|---|
| vtv therapeutics inc | 81.09 |
| mineralys therapeutics inc | 10.37 |
Additions to existing portfolio by Samsara BioCapital, LLC
Reductions
| Ticker | % Reduced |
|---|---|
| aura biosciences inc | -41.52 |
| rhythm pharmaceuticals inc | -40.00 |
| palvella therapeutics inc ne | -38.3 |
| upstream bio inc | -33.33 |
| terns pharmaceuticals inc | -33.00 |
| zymeworks inc | -33.00 |
| arcellx inc | -20.00 |
| bolt biotherapeutics inc | -6.91 |
Samsara BioCapital, LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| cargo therapeutics inc | -18,192,600 |
| hillevax inc | -795,278 |
| artiva biotherapeutics inc | -440,416 |
| tango therapeutics inc | -1,075,200 |
Samsara BioCapital, LLC got rid off the above stocks
Sector Distribution
SAMSARA BIOCAPITAL, LLC has about 63.5% of it's holdings in Others sector.
| Sector | % |
|---|---|
| Others | 63.5 |
| Healthcare | 36.5 |
Market Cap. Distribution
SAMSARA BIOCAPITAL, LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.
| Category | % |
|---|---|
| UNALLOCATED | 63.5 |
| SMALL-CAP | 30.7 |
| MID-CAP | 2.4 |
| MICRO-CAP | 2.4 |
Stocks belong to which Index?
About 31.5% of the stocks held by SAMSARA BIOCAPITAL, LLC either belong to S&P 500 or RUSSELL 2000 index.
| Index | % |
|---|---|
| Others | 68.5 |
| RUSSELL 2000 | 31.5 |
Samsara BioCapital, LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Samsara BioCapital, LLC
SAMSARA BIOCAPITAL, LLC has 27 stocks in it's portfolio. About 89.4% of the portfolio is in top 10 stocks. AVTE proved to be the most loss making stock for the portfolio. was the most profitable stock for SAMSARA BIOCAPITAL, LLC last quarter.
Last Reported on: 14 Nov, 2025| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ACLX | arcellx inc | 0.87 | 81,165 | 6,663,650 | reduced | -20.00 | ||
| AQST | aquestive therapeutics inc | 1.82 | 2,500,000 | 13,975,000 | new | |||
| AURA | aura biosciences inc | 0.47 | 584,849 | 3,614,370 | reduced | -41.52 | ||
| AVTE | jade biosciences inc | 0.60 | 531,163 | 4,583,940 | unchanged | 0.00 | ||
| BOLT | bolt biotherapeutics inc | 0.03 | 48,830 | 259,776 | reduced | -6.91 | ||
| GOSS | gossamer bio inc | 2.10 | 6,130,270 | 16,122,600 | unchanged | 0.00 | ||
| HLVX | hillevax inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| NKTX | nkarta inc | 1.02 | 3,768,040 | 7,799,830 | unchanged | 0.00 | ||
| NUVB | nuvation bio inc | 0.00 | 133,333 | 26,947 | unchanged | 0.00 | ||
| RYTM | rhythm pharmaceuticals inc | 0.40 | 30,285 | 3,058,480 | reduced | -40.00 | ||
| SRRK | scholar rock hldg corp | 27.29 | 5,612,900 | 209,024,000 | unchanged | 0.00 | ||
| SRZN | surrozen inc | 0.41 | 241,400 | 3,110,440 | unchanged | 0.00 | ||
| SRZN | surrozen inc | 0.00 | 99,999 | 1,780 | unchanged | 0.00 | ||
| STRO | sutro biopharma inc | 0.25 | 2,196,810 | 1,907,710 | unchanged | 0.00 | ||
| TERN | terns pharmaceuticals inc | 0.13 | 135,573 | 1,018,150 | reduced | -33.00 | ||
| TNGX | tango therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| VTVT | vtv therapeutics inc | 1.14 | 374,461 | 8,743,660 | added | 81.09 | ||
| ZYME | zymeworks inc | 0.46 | 207,901 | 3,550,950 | reduced | -33.00 | ||
| mineralys therapeutics inc | 31.01 | 6,263,150 | 237,499,000 | added | 10.37 | |||
| kalaris therapeutics inc | 8.64 | 11,448,100 | 66,169,900 | unchanged | 0.00 | |||