Latest Samsara BioCapital, LLC Stock Portfolio
$1.03Billion– No. of Holdings #22
Samsara BioCapital, LLC Performance:
2026 Q1: -1.94%YTD: -1.94%2025: 26.2%
Performance for 2026 Q1 is -1.94%, and YTD is -1.94%, and 2025 is 26.2%.
About Samsara BioCapital, LLC and 13F Hedge Fund Stock Holdings
SAMSARA BIOCAPITAL, LLC is a hedge fund based in Palo Alto, CA. On 2026-05-15, the fund reported it's updated stock portfolio. In the 13F Holdings report, SAMSARA BIOCAPITAL, LLC reported an equity portfolio of $1 Billions as of 31 Mar, 2026.
The top stock holdings of SAMSARA BIOCAPITAL, LLC are SRRK, , . The fund has invested 33% of it's portfolio in SCHOLAR ROCK HLDG CORP and 15.5% of portfolio in MINERALYS THERAPEUTICS INC.
The fund managers got completely rid off CONTINEUM THERAPEUTICS INC and NUVATION BIO INC (NUVB) stocks. They significantly reduced their stock positions in PALVELLA THERAPEUTICS INC NE and X4 PHARMACEUTICALS INC (XFOR). SAMSARA BIOCAPITAL, LLC opened new stock positions in SPYGLASS PHARMA INC and COHERUS ONCOLOGY INC (CHRS). The fund showed a lot of confidence in some stocks as they added substantially to SUTRO BIOPHARMA INC (STRO) and ALUMIS INC.
The top stock holdings of SAMSARA BIOCAPITAL, LLC are SRRK, , . The fund has invested 33% of it's portfolio in SCHOLAR ROCK HLDG CORP and 15.5% of portfolio in MINERALYS THERAPEUTICS INC.
The fund managers got completely rid off CONTINEUM THERAPEUTICS INC and NUVATION BIO INC (NUVB) stocks. They significantly reduced their stock positions in PALVELLA THERAPEUTICS INC NE and X4 PHARMACEUTICALS INC (XFOR). SAMSARA BIOCAPITAL, LLC opened new stock positions in SPYGLASS PHARMA INC and COHERUS ONCOLOGY INC (CHRS). The fund showed a lot of confidence in some stocks as they added substantially to SUTRO BIOPHARMA INC (STRO) and ALUMIS INC.
Samsara BioCapital, LLC Equity Portfolio Value
Last Reported on: 15 May, 2026
Samsara BioCapital, LLC Annual Return Estimates Vs S&P 500
Our best estimate is that SAMSARA BIOCAPITAL, LLC made a return of -1.94% in the last quarter. In trailing 12 months, it's portfolio return was 68.19%.
- Performance
- S&P 500
New Buys
| Ticker | $ Bought |
|---|---|
| spyglass pharma inc | 54,668,900 |
| agomab therapeutics nv | 6,294,000 |
| coherus oncology inc | 5,794,280 |
New stocks bought by Samsara BioCapital, LLC
Additions
| Ticker | % Inc. |
|---|---|
| sutro biopharma inc | 419 |
| alumis inc | 10.22 |
Additions to existing portfolio by Samsara BioCapital, LLC
Reductions
| Ticker | % Reduced |
|---|---|
| palvella therapeutics inc ne | -63.33 |
| abivax sa | -25.00 |
| x4 pharmaceuticals inc | -6.5 |
Samsara BioCapital, LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| nuvation bio inc | -40,959 |
| contineum therapeutics inc | -825,760 |
Samsara BioCapital, LLC got rid off the above stocks
Sector Distribution
SAMSARA BIOCAPITAL, LLC has about 57.5% of it's holdings in Others sector.
- Others
- Healthcare
| Sector | % |
|---|---|
| Others | 57.5 |
| Healthcare | 42.5 |
Market Cap. Distribution
SAMSARA BIOCAPITAL, LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.
- UNALLOCATED
- MID-CAP
- MICRO-CAP
- SMALL-CAP
| Category | % |
|---|---|
| UNALLOCATED | 57.5 |
| MID-CAP | 33.6 |
| MICRO-CAP | 5.7 |
| SMALL-CAP | 2.6 |
Stocks belong to which Index?
About 39.5% of the stocks held by SAMSARA BIOCAPITAL, LLC either belong to S&P 500 or RUSSELL 2000 index.
- Others
- RUSSELL 2000
| Index | % |
|---|---|
| Others | 60.5 |
| RUSSELL 2000 | 39.5 |
Samsara BioCapital, LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Samsara BioCapital, LLC
SAMSARA BIOCAPITAL, LLC has 22 stocks in it's portfolio. About 92% of the portfolio is in top 10 stocks. proved to be the most loss making stock for the portfolio. was the most profitable stock for SAMSARA BIOCAPITAL, LLC last quarter.
Last Reported on: 15 May, 2026| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ACLX | arcellx inc | 0.68 | 60,873 | 6,989,440 | unchanged | 0.00 | ||
| AQST | aquestive therapeutics inc | 1.01 | 2,500,000 | 10,375,000 | unchanged | 0.00 | ||
| AVTE | jade biosciences inc | 1.32 | 968,798 | 13,611,600 | unchanged | 0.00 | ||
| CHRS | coherus oncology inc | 0.56 | 3,428,570 | 5,794,280 | new | |||
| GOSS | gossamer bio inc | 0.23 | 7,222,560 | 2,372,610 | unchanged | 0.00 | ||
| IVA | inventiva sa | 2.80 | 5,194,800 | 28,831,200 | unchanged | 0.00 | ||
| NKTX | nkarta inc | 0.72 | 3,507,670 | 7,401,180 | unchanged | 0.00 | ||
| NUVB | nuvation bio inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| RANI | rani therapeutics hldgs inc | 0.61 | 8,500,000 | 6,245,800 | unchanged | 0.00 | ||
| SRRK | scholar rock hldg corp | 32.95 | 6,897,650 | 339,089,000 | unchanged | 0.00 | ||
| STRO | sutro biopharma inc | 2.57 | 1,062,870 | 26,476,100 | added | 419 | ||
| VTVT | vtv therapeutics inc | 1.15 | 298,496 | 11,838,400 | unchanged | 0.00 | ||
| XFOR | x4 pharmaceuticals inc | 0.74 | 1,832,570 | 7,568,500 | reduced | -6.5 | ||
| mineralys therapeutics inc | 15.46 | 5,871,020 | 159,046,000 | unchanged | 0.00 | |||
| alumis inc | 13.58 | 6,345,220 | 139,785,000 | added | 10.22 | |||
| septerna inc | 7.35 | 3,149,130 | 75,673,500 | unchanged | 0.00 | |||
| kalaris therapeutics inc | 7.26 | 12,948,100 | 74,710,400 | unchanged | 0.00 | |||
| spyglass pharma inc | 5.31 | 2,109,950 | 54,668,900 | new | ||||
| neurogene inc | 3.36 | 1,717,130 | 34,617,300 | unchanged | 0.00 | |||
| upstream bio inc | 0.64 | 736,047 | 6,624,420 | unchanged | 0.00 | |||