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Latest Samsara BioCapital, LLC Stock Portfolio

$1.22Billion | No. of Holdings #24

Samsara BioCapital, LLC Performance

2026 Q2+9.45%
YTD+7.33%
2025+26.20%

About Samsara BioCapital, LLC and 13F Hedge Fund Stock Holdings

SAMSARA BIOCAPITAL, LLC is a hedge fund based in Palo Alto, CA. On 2026-08-14, the fund reported it's updated stock portfolio. In the 13F Holdings report, SAMSARA BIOCAPITAL, LLC reported an equity portfolio of $1.2 Billions as of 30 Jun, 2026. <br><br> The top stock holdings of SAMSARA BIOCAPITAL, LLC are SRRK, , . The fund has invested 31.2% of it's portfolio in SCHOLAR ROCK HLDG CORP and 14.7% of portfolio in ALUMIS INC. <br><br> The fund managers got completely rid off ARCELLX INC (ACLX) and PALVELLA THERAPEUTICS INC NE stocks. They significantly reduced their stock positions in UPSTREAM BIO INC, JADE BIOSCIENCES INC (AVTE) and X4 PHARMACEUTICALS INC (XFOR). SAMSARA BIOCAPITAL, LLC opened new stock positions in ALAMAR BIOSCIENCES INC and ELOXX PHARMACEUTICALS INC (ELOX). The fund showed a lot of confidence in some stocks as they added substantially to RANI THERAPEUTICS HLDGS INC (RANI) and INVENTIVA SA (IVA).
Samsara BioCapital, LLC Equity Portfolio Value
Last Reported on: 14 Aug, 2026
$1.22Billion
  as of Aug 14, 2026

Samsara BioCapital, LLC Annual Return Estimates Vs S&P 500

Our best estimate is that SAMSARA BIOCAPITAL, LLC made a return of 9.45% in the last quarter. In trailing 12 months, it's portfolio return was 98.09%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
alamar biosciences inc67,191,600
parabilis medicines inc15,218,900
artiva biotherapeutics inc9,262,150
eloxx pharmaceuticals inc5,552,000
New stocks bought by Samsara BioCapital, LLC

Additions

Ticker% Inc.
rani therapeutics hldgs inc21.99
inventiva sa21.56
Additions to existing portfolio by Samsara BioCapital, LLC

Reductions

Ticker% Reduced
upstream bio inc-51.94
jade biosciences inc-24.01
x4 pharmaceuticals inc-23.85
abivax sa-2.63
kalaris therapeutics inc-0.52
Samsara BioCapital, LLC reduced stake in above stock

Sold off

Ticker$ Sold
arcellx inc-6,989,440
palvella therapeutics inc ne-4,790,550
Samsara BioCapital, LLC got rid off the above stocks

Sector Distribution

SAMSARA BIOCAPITAL, LLC has about 60.3% of it's holdings in Others sector.

  • Others
  • Healthcare
Sector%
Others60.3
Healthcare39.7

Market Cap. Distribution

SAMSARA BIOCAPITAL, LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.

  • UNALLOCATED
  • MID-CAP
  • SMALL-CAP
  • MICRO-CAP
Category%
UNALLOCATED60.3
MID-CAP31.2
SMALL-CAP5.6
MICRO-CAP2.8

Stocks belong to which Index?

About 37.1% of the stocks held by SAMSARA BIOCAPITAL, LLC either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • RUSSELL 2000
Index%
Others62.9
RUSSELL 200037.1
Top 5 Winners (%)%
neurogene inc
56.0 %
AVTE
jade biosciences inc
51.2 %
septerna inc
39.4 %
NKTX
nkarta inc
34.1 %
STRO
sutro biopharma inc
33.3 %
Top 5 Winners ($)$
SRRK
scholar rock hldg corp
40.3 M
alumis inc
38.8 M
septerna inc
29.8 M
neurogene inc
19.4 M
STRO
sutro biopharma inc
8.8 M
Top 5 Losers (%)%
GOSS
gossamer bio inc
-49.9 %
IVA
inventiva sa
-29.9 %
kalaris therapeutics inc
-29.4 %
CHRS
coherus oncology inc
-17.2 %
upstream bio inc
-17.1 %
Top 5 Losers ($)$
kalaris therapeutics inc
-22.0 M
IVA
inventiva sa
-10.2 M
spyglass pharma inc
-7.7 M
GOSS
gossamer bio inc
-1.2 M
upstream bio inc
-1.1 M

Samsara BioCapital, LLC Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Samsara BioCapital, LLC

SAMSARA BIOCAPITAL, LLC has 24 stocks in it's portfolio. About 90.5% of the portfolio is in top 10 stocks. proved to be the most loss making stock for the portfolio. SRRK was the most profitable stock for SAMSARA BIOCAPITAL, LLC last quarter.

$1.22BTotal Value
26.00Positions
14 Aug, 2026Last Reported
Current holdings of Current Stock Holdings of Samsara BioCapital, LLC, last reported on 14 Aug, 2026. Select a row with a linked ticker to view its historical trend.
ExpandHoldingsorted ascending% PortfolioShares Held$ Value% Change
ELOX
Eloxx Pharmaceuticals Inc

Eloxx Pharmaceuticals Inc

ELOX
Samsara BioCapital, LLC's holding in Eloxx Pharmaceuticals Inc over time
0.46%400,000
$5.55M
0.46%
new position
IVA
Inventiva Sa

Inventiva Sa

IVA
Samsara BioCapital, LLC's holding in Inventiva Sa over time
1.96%6,314,800
$23.87M
1.96%
increased 21.56 percentadded
Com
Alumis Inc

Alumis Inc

Samsara BioCapital, LLC's holding in Alumis Inc over time
14.67%6,345,220
$178.55M
14.67%
unchanged 0 percentunchanged
Com
Mineralys Therapeutics Inc

Mineralys Therapeutics Inc

Samsara BioCapital, LLC's holding in Mineralys Therapeutics Inc over time
13.01%5,871,020
$158.40M
13.01%
unchanged 0 percentunchanged
Com
Septerna Inc

Septerna Inc

Samsara BioCapital, LLC's holding in Septerna Inc over time
8.66%3,149,130
$105.46M
8.66%
unchanged 0 percentunchanged
Common Stock
Alamar Biosciences Inc

Alamar Biosciences Inc

Samsara BioCapital, LLC's holding in Alamar Biosciences Inc over time
5.52%2,480,310
$67.19M
5.52%
new position
Com
Neurogene Inc

Neurogene Inc

Samsara BioCapital, LLC's holding in Neurogene Inc over time
4.44%1,717,130
$54.00M
4.44%
unchanged 0 percentunchanged
Com
Kalaris Therapeutics Inc

Kalaris Therapeutics Inc

Samsara BioCapital, LLC's holding in Kalaris Therapeutics Inc over time
4.31%12,881,200
$52.43M
4.31%
decreased 0.52 percentreduced
Com Shs
Spyglass Pharma Inc

Spyglass Pharma Inc

Samsara BioCapital, LLC's holding in Spyglass Pharma Inc over time
3.86%2,109,950
$46.97M
3.86%
unchanged 0 percentunchanged