Latest Samsara BioCapital, LLC Stock Portfolio
$1.03Billion | No. of Holdings #22
Samsara BioCapital, LLC Performance
2026 Q1-1.94%
YTD-1.94%
2025+26.20%
About Samsara BioCapital, LLC and 13F Hedge Fund Stock Holdings
SAMSARA BIOCAPITAL, LLC is a hedge fund based in Palo Alto, CA. On 2026-05-15, the fund reported it's updated stock portfolio. In the 13F Holdings report, SAMSARA BIOCAPITAL, LLC reported an equity portfolio of $1 Billions as of 31 Mar, 2026. <br><br> The top stock holdings of SAMSARA BIOCAPITAL, LLC are SRRK, , . The fund has invested 33% of it's portfolio in SCHOLAR ROCK HLDG CORP and 15.5% of portfolio in MINERALYS THERAPEUTICS INC. <br><br> The fund managers got completely rid off CONTINEUM THERAPEUTICS INC and NUVATION BIO INC (NUVB) stocks. They significantly reduced their stock positions in PALVELLA THERAPEUTICS INC NE and X4 PHARMACEUTICALS INC (XFOR). SAMSARA BIOCAPITAL, LLC opened new stock positions in SPYGLASS PHARMA INC and COHERUS ONCOLOGY INC (CHRS). The fund showed a lot of confidence in some stocks as they added substantially to SUTRO BIOPHARMA INC (STRO) and ALUMIS INC.
Samsara BioCapital, LLC Equity Portfolio Value
Last Reported on: 15 May, 2026
$1.03Billion
as of May 15, 2026Samsara BioCapital, LLC Annual Return Estimates Vs S&P 500
Our best estimate is that SAMSARA BIOCAPITAL, LLC made a return of -1.94% in the last quarter. In trailing 12 months, it's portfolio return was 68.19%.
- Performance
- S&P 500
New Buys
| Ticker | $ Bought |
|---|---|
| spyglass pharma inc | 54,668,900 |
| agomab therapeutics nv | 6,294,000 |
| coherus oncology inc | 5,794,280 |
New stocks bought by Samsara BioCapital, LLC
Additions
| Ticker | % Inc. |
|---|---|
| sutro biopharma inc | 419 |
| alumis inc | 10.22 |
Additions to existing portfolio by Samsara BioCapital, LLC
Reductions
| Ticker | % Reduced |
|---|---|
| palvella therapeutics inc ne | -63.33 |
| abivax sa | -25.00 |
| x4 pharmaceuticals inc | -6.5 |
Samsara BioCapital, LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| nuvation bio inc | -40,959 |
| contineum therapeutics inc | -825,760 |
Samsara BioCapital, LLC got rid off the above stocks
Sector Distribution
SAMSARA BIOCAPITAL, LLC has about 57.5% of it's holdings in Others sector.
- Others
- Healthcare
| Sector | % |
|---|---|
| Others | 57.5 |
| Healthcare | 42.5 |
Market Cap. Distribution
SAMSARA BIOCAPITAL, LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.
- UNALLOCATED
- MID-CAP
- MICRO-CAP
- SMALL-CAP
| Category | % |
|---|---|
| UNALLOCATED | 57.5 |
| MID-CAP | 33.6 |
| MICRO-CAP | 5.7 |
| SMALL-CAP | 2.6 |
Stocks belong to which Index?
About 39.5% of the stocks held by SAMSARA BIOCAPITAL, LLC either belong to S&P 500 or RUSSELL 2000 index.
- Others
- RUSSELL 2000
| Index | % |
|---|---|
| Others | 60.5 |
| RUSSELL 2000 | 39.5 |
| Top 5 Losers ($) | $ | |
|---|---|---|
mineralys therapeutics inc | -54.0 M | |
kalaris therapeutics inc | -34.6 M | |
| GOSS | gossamer bio inc | -20.0 M |
upstream bio inc | -13.4 M | |
septerna inc | -12.1 M | |
Samsara BioCapital, LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Samsara BioCapital, LLC
SAMSARA BIOCAPITAL, LLC has 22 stocks in it's portfolio. About 92% of the portfolio is in top 10 stocks. proved to be the most loss making stock for the portfolio. was the most profitable stock for SAMSARA BIOCAPITAL, LLC last quarter.
$1.03BTotal Value
24.00Positions
15 May, 2026Last Reported
| Expand | Holdingsorted ascending | % Portfolio | Shares Held | $ Value | % Change |
|---|---|---|---|---|---|
 Arcellx Inc Arcellx IncACLX Samsara BioCapital, LLC's holding in Arcellx Inc over time | 0.68% | 60,873 | $6.99M 0.68% | 0%unchanged 0 percentunchanged | |
 Aquestive Therapeutics Inc Samsara BioCapital, LLC's holding in Aquestive Therapeutics Inc over time | 1.01% | 2,500,000 | $10.38M 1.01% | 0%unchanged 0 percentunchanged | |
 Jade Biosciences Inc Samsara BioCapital, LLC's holding in Jade Biosciences Inc over time | 1.32% | 968,798 | $13.61M 1.32% | 0%unchanged 0 percentunchanged | |
 Coherus Oncology Inc Samsara BioCapital, LLC's holding in Coherus Oncology Inc over time | 0.56% | 3,428,570 | $5.79M 0.56% | Newnew position | |
 Gossamer Bio Inc Gossamer Bio IncGOSS Samsara BioCapital, LLC's holding in Gossamer Bio Inc over time | 0.23% | 7,222,560 | $2.37M 0.23% | 0%unchanged 0 percentunchanged | |
 IVA Inventiva SaInventiva SaIVA | 2.8% | 5,194,800 | $28.83M 2.8% | 0%unchanged 0 percentunchanged | |
 Nkarta Inc Nkarta IncNKTX Samsara BioCapital, LLC's holding in Nkarta Inc over time | 0.72% | 3,507,670 | $7.40M 0.72% | 0%unchanged 0 percentunchanged | |
 Nuvation Bio Inc Nuvation Bio IncNUVB Samsara BioCapital, LLC's holding in Nuvation Bio Inc over time | 0% | 0.00 | $0.00 0% | 100%decreased 100 percentsold off | |
 Rani Therapeutics Hldgs Inc Samsara BioCapital, LLC's holding in Rani Therapeutics Hldgs Inc over time | 0.61% | 8,500,000 | $6.25M 0.61% | 0%unchanged 0 percentunchanged | |
 Scholar Rock Hldg Corp Samsara BioCapital, LLC's holding in Scholar Rock Hldg Corp over time | 32.95% | 6,897,650 | $339.09M 32.95% | 0%unchanged 0 percentunchanged | |
 Sutro Biopharma Inc Samsara BioCapital, LLC's holding in Sutro Biopharma Inc over time | 2.57% | 1,062,870 | $26.48M 2.57% | 419.73%increased 419.73 percentadded | |
 Vtv Therapeutics Inc Samsara BioCapital, LLC's holding in Vtv Therapeutics Inc over time | 1.15% | 298,496 | $11.84M 1.15% | 0%unchanged 0 percentunchanged | |
 X4 Pharmaceuticals Inc Samsara BioCapital, LLC's holding in X4 Pharmaceuticals Inc over time | 0.74% | 1,832,570 | $7.57M 0.74% | 6.5%decreased 6.5 percentreduced | |
Com Mineralys Therapeutics IncMineralys Therapeutics Inc | 15.46% | 5,871,020 | $159.05M 15.46% | 0%unchanged 0 percentunchanged | |
Com Alumis IncAlumis Inc | 13.58% | 6,345,220 | $139.78M 13.58% | 10.22%increased 10.22 percentadded | |
Com Septerna IncSepterna Inc | 7.35% | 3,149,130 | $75.67M 7.35% | 0%unchanged 0 percentunchanged | |
Com Kalaris Therapeutics IncKalaris Therapeutics Inc | 7.26% | 12,948,100 | $74.71M 7.26% | 0%unchanged 0 percentunchanged | |
Com Shs Spyglass Pharma IncSpyglass Pharma Inc | 5.31% | 2,109,950 | $54.67M 5.31% | Newnew position | |
Com Neurogene IncNeurogene Inc | 3.36% | 1,717,130 | $34.62M 3.36% | 0%unchanged 0 percentunchanged | |
Com Upstream Bio IncUpstream Bio Inc | 0.64% | 736,047 | $6.62M 0.64% | 0%unchanged 0 percentunchanged | |