Latest Foresite Capital Management V, LLC Stock Portfolio

Foresite Capital Management V, LLC Performance:

2025 Q4: 32.4%YTD: 44.2%2024: 7.68%

Performance for 2025 Q4 is 32.4%, and YTD is 44.2%, and 2024 is 7.68%.

About Foresite Capital Management V, LLC and 13F Hedge Fund Stock Holdings

On 2026-02-17, the fund reported it's updated stock portfolio. In the 13F Holdings report, Foresite Capital Management V, LLC reported an equity portfolio of $164.4 Millions as of 31 Dec, 2025.

The top stock holdings of Foresite Capital Management V, LLC are , , . The fund has invested 34.3% of it's portfolio in ALUMIS INC. and 25.4% of portfolio in CG ONCOLOGY, INC.

Foresite Capital Management V, LLC opened new stock positions in NATERA, INC. (NTRA).

Foresite Capital Management V, LLC Annual Return Estimates Vs S&P 500

Our best estimate is that Foresite Capital Management V, LLC made a return of 32.4% in the last quarter. In trailing 12 months, it's portfolio return was 44.2%.

Performance
S&P 500

New Buys

Ticker	$ Bought
natera, inc.	15,430,600

New stocks bought by Foresite Capital Management V, LLC

Additions

No additions were made to existing positions by Foresite Capital Management V, LLC

Reductions

None of the existing positions were reduced by Foresite Capital Management V, LLC

Sold off

None of the stocks were completely sold off by Foresite Capital Management V, LLC

Sector Distribution

Foresite Capital Management V, LLC has about 76.3% of it's holdings in Others sector.

Sector	%
Others	76.3
Healthcare	18.3
Consumer Defensive	5.4

Market Cap. Distribution

Foresite Capital Management V, LLC has about 9.4% of it's portfolio invested in the large-cap and mega-cap stocks.

Category	%
UNALLOCATED	76.3
LARGE-CAP	9.4
SMALL-CAP	8.9
MID-CAP	5.4

Stocks belong to which Index?

About 14.3% of the stocks held by Foresite Capital Management V, LLC either belong to S&P 500 or RUSSELL 2000 index.

Index	%
Others	85.7
RUSSELL 2000	14.3

Top 5 Winners (%)		%
	alumis inc.	144.6 %
LYEL	lyell immunopharma, inc.	89.5 %
	maze therapeutics, inc.	59.8 %
	disc medicine, inc.	20.2 %
	cg oncology, inc.	3.1 %

Top 5 Winners ($)		$
	alumis inc.	33.3 M
LYEL	lyell immunopharma, inc.	6.9 M
	disc medicine, inc.	4.0 M
	maze therapeutics, inc.	1.3 M
	cg oncology, inc.	1.2 M

Top 5 Losers (%)		%
HIMS	hims & hers health, inc.	-42.8 %

Top 5 Losers ($)		$
HIMS	hims & hers health, inc.	-6.6 M

Foresite Capital Management V, LLC Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Foresite Capital Management V, LLC

Foresite Capital Management V, LLC has 7 stocks in it's portfolio. HIMS proved to be the most loss making stock for the portfolio. was the most profitable stock for Foresite Capital Management V, LLC last quarter.

Last Reported on: 17 Feb, 2026

Ticker	Namesorted ascending	% Portfolio	Shares Held	$ Value	Type	% Change
HIMS	hims & hers health, inc.	5.39	273,151	8,869,210	unchanged	0.00

LYEL	lyell immunopharma, inc.	8.93	477,078	14,684,500	unchanged	0.00

NTRA	natera, inc.	9.39	67,356	15,430,600	new

	alumis inc.	34.31	5,779,350	56,406,400	unchanged	0.00

	cg oncology, inc.	25.36	1,004,050	41,688,200	unchanged	0.00

	disc medicine, inc.	14.45	299,069	23,749,100	unchanged	0.00

	maze therapeutics, inc.	2.17	86,291	3,575,040	unchanged	0.00