Latest Column Group LLC Stock Portfolio
Column Group LLC Performance:
2025 Q4: -4.72%YTD: 20.08%2024: -53.93%
Performance for 2025 Q4 is -4.72%, and YTD is 20.08%, and 2024 is -53.93%.
About Column Group LLC and 13F Hedge Fund Stock Holdings
On 2026-02-13, the fund reported it's updated stock portfolio. In the 13F Holdings report, Column Group LLC reported an equity portfolio of $82.8 Millions as of 31 Dec, 2025.
The top stock holdings of Column Group LLC are SRZN, ORIC, TNYA. The fund has invested 50.5% of it's portfolio in SURROZEN, INC. and 35% of portfolio in ORIC PHARMACEUTICALS INC.
They significantly reduced their stock positions in RAPT THERAPEUTICS INC (RAPT). The fund showed a lot of confidence in some stocks as they added substantially to SURROZEN, INC. (SRZN).
The top stock holdings of Column Group LLC are SRZN, ORIC, TNYA. The fund has invested 50.5% of it's portfolio in SURROZEN, INC. and 35% of portfolio in ORIC PHARMACEUTICALS INC.
They significantly reduced their stock positions in RAPT THERAPEUTICS INC (RAPT). The fund showed a lot of confidence in some stocks as they added substantially to SURROZEN, INC. (SRZN).
Column Group LLC Annual Return Estimates Vs S&P 500
Our best estimate is that Column Group LLC made a return of -4.72% in the last quarter. In trailing 12 months, it's portfolio return was 20.08%.
- Performance
- S&P 500
New Buys
Additions
| Ticker | % Inc. |
|---|---|
| surrozen, inc. | 23.44 |
Additions to existing portfolio by Column Group LLC
Reductions
| Ticker | % Reduced |
|---|---|
| rapt therapeutics inc | -5.9 |
Column Group LLC reduced stake in above stock
Sold off
Sector Distribution
Column Group LLC has about 100% of it's holdings in Healthcare sector.
- Healthcare
| Sector | % |
|---|---|
| Healthcare | 100 |
Market Cap. Distribution
Column Group LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.
- MICRO-CAP
- SMALL-CAP
| Category | % |
|---|---|
| MICRO-CAP | 58.6 |
| SMALL-CAP | 41.4 |
Stocks belong to which Index?
About 49.5% of the stocks held by Column Group LLC either belong to S&P 500 or RUSSELL 2000 index.
- Others
- RUSSELL 2000
| Index | % |
|---|---|
| Others | 50.5 |
| RUSSELL 2000 | 49.5 |
Column Group LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Column Group LLC
Column Group LLC has 5 stocks in it's portfolio. ORIC proved to be the most loss making stock for the portfolio. SRZN was the most profitable stock for Column Group LLC last quarter.
Last Reported on: 13 Feb, 2026| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ORIC | oric pharmaceuticals inc. | 34.98 | 3,540,780 | 28,963,600 | unchanged | 0.00 | ||
| RAPT | rapt therapeutics inc | 6.39 | 156,270 | 5,292,880 | reduced | -5.9 | ||
| RVMD | revolution medicines inc | 0.00 | 46.00 | 3,664 | unchanged | 0.00 | ||
| SRZN | surrozen, inc. | 50.54 | 1,851,350 | 41,840,500 | added | 23.44 | ||
| TNYA | tenaya therapeutics, inc. | 8.08 | 9,400,290 | 6,693,010 | unchanged | 0.00 | ||