Latest SR ONE CAPITAL MANAGEMENT, LP Stock Portfolio
$915Million– No. of Holdings #14
SR ONE CAPITAL MANAGEMENT, LP Performance:
2026 Q1: 6.69%YTD: 6.69%2025: 37.52%
Performance for 2026 Q1 is 6.69%, and YTD is 6.69%, and 2025 is 37.52%.
About SR ONE CAPITAL MANAGEMENT, LP and 13F Hedge Fund Stock Holdings
On 2026-05-14, the fund reported it's updated stock portfolio. In the 13F Holdings report, SR One Capital Management, LP reported an equity portfolio of $915.4 Millions as of 31 Mar, 2026.
The top stock holdings of SR One Capital Management, LP are ACLX, , . The fund has invested 29.4% of it's portfolio in ARCELLX, INC. and 16.6% of portfolio in VERADERMICS, INC.
SR One Capital Management, LP opened new stock positions in VERADERMICS, INC..
The top stock holdings of SR One Capital Management, LP are ACLX, , . The fund has invested 29.4% of it's portfolio in ARCELLX, INC. and 16.6% of portfolio in VERADERMICS, INC.
SR One Capital Management, LP opened new stock positions in VERADERMICS, INC..
SR ONE CAPITAL MANAGEMENT, LP Equity Portfolio Value
Last Reported on: 14 May, 2026
SR ONE CAPITAL MANAGEMENT, LP Annual Return Estimates Vs S&P 500
Our best estimate is that SR One Capital Management, LP made a return of 6.69% in the last quarter. In trailing 12 months, it's portfolio return was 62.77%.
- Performance
- S&P 500
New Buys
| Ticker | $ Bought |
|---|---|
| veradermics, inc. | 151,678,000 |
New stocks bought by SR ONE CAPITAL MANAGEMENT, LP
Additions
Reductions
Sold off
Sector Distribution
SR One Capital Management, LP has about 55.1% of it's holdings in Healthcare sector.
- Healthcare
- Others
| Sector | % |
|---|---|
| Healthcare | 55.1 |
| Others | 41.4 |
| 3.5 |
Market Cap. Distribution
SR One Capital Management, LP has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.
- UNALLOCATED
- MID-CAP
- SMALL-CAP
| Category | % |
|---|---|
| UNALLOCATED | 41.4 |
| MID-CAP | 40 |
| SMALL-CAP | 17.8 |
Stocks belong to which Index?
About 44.2% of the stocks held by SR One Capital Management, LP either belong to S&P 500 or RUSSELL 2000 index.
- Others
- RUSSELL 2000
| Index | % |
|---|---|
| Others | 55.8 |
| RUSSELL 2000 | 44.2 |
SR ONE CAPITAL MANAGEMENT, LP Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of SR ONE CAPITAL MANAGEMENT, LP
SR One Capital Management, LP has 14 stocks in it's portfolio. About 96.5% of the portfolio is in top 10 stocks. proved to be the most loss making stock for the portfolio. ACLX was the most profitable stock for SR One Capital Management, LP last quarter.
Last Reported on: 14 May, 2026| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ACLX | arcellx, inc. | 29.43 | 2,346,630 | 269,440,000 | unchanged | 0.00 | ||
| CRSP | crispr therapeutics ag | 10.59 | 2,038,760 | 96,984,000 | unchanged | 0.00 | ||
| DSGN | design therapeutics, inc. | 7.59 | 6,526,480 | 69,441,700 | unchanged | 0.00 | ||
| NKTX | nkarta, inc. | 0.77 | 3,333,330 | 7,033,330 | unchanged | 0.00 | ||
| ORIC | oric pharmaceuticals, inc. | 6.39 | 4,514,930 | 58,476,900 | unchanged | 0.00 | ||
| RARE | ultragenyx pharmaceutical inc. | 0.32 | 137,753 | 2,885,920 | unchanged | 0.00 | ||
| SBTX | ars pharmaceuticals, inc. | 3.52 | 4,012,900 | 32,223,600 | unchanged | 0.00 | ||
| veradermics, inc. | 16.57 | 2,401,870 | 151,678,000 | new | ||||
| zenas biopharma, inc | 10.76 | 5,037,850 | 98,490,000 | unchanged | 0.00 | |||
| alumis inc. | 4.72 | 1,959,900 | 43,176,500 | unchanged | 0.00 | |||
| mineralys therapeutics inc. | 4.63 | 1,563,970 | 42,367,800 | unchanged | 0.00 | |||
| oruka therapeutics, inc | 2.31 | 430,330 | 21,107,700 | unchanged | 0.00 | |||
| oculis holding ag | 1.86 | 641,022 | 17,044,800 | unchanged | 0.00 | |||
| engene holdings inc. | 0.56 | 747,750 | 5,092,180 | unchanged | 0.00 | |||