Latest SR ONE CAPITAL MANAGEMENT, LP Stock Portfolio
$915Million | No. of Holdings #14
SR ONE CAPITAL MANAGEMENT, LP Performance
2026 Q1+6.69%
YTD+6.69%
2025+37.52%
About SR ONE CAPITAL MANAGEMENT, LP and 13F Hedge Fund Stock Holdings
On 2026-05-14, the fund reported it's updated stock portfolio. In the 13F Holdings report, SR One Capital Management, LP reported an equity portfolio of $915.4 Millions as of 31 Mar, 2026. <br><br> The top stock holdings of SR One Capital Management, LP are ACLX, , . The fund has invested 29.4% of it's portfolio in ARCELLX, INC. and 16.6% of portfolio in VERADERMICS, INC. <br><br> SR One Capital Management, LP opened new stock positions in VERADERMICS, INC..
SR ONE CAPITAL MANAGEMENT, LP Equity Portfolio Value
Last Reported on: 14 May, 2026
$915Million
as of May 14, 2026SR ONE CAPITAL MANAGEMENT, LP Annual Return Estimates Vs S&P 500
Our best estimate is that SR One Capital Management, LP made a return of 6.69% in the last quarter. In trailing 12 months, it's portfolio return was 62.77%.
- Performance
- S&P 500
New Buys
| Ticker | $ Bought |
|---|---|
| veradermics, inc. | 151,678,000 |
New stocks bought by SR ONE CAPITAL MANAGEMENT, LP
Additions
No additions were made to existing positions by SR ONE CAPITAL MANAGEMENT, LP
Reductions
None of the existing positions were reduced by SR ONE CAPITAL MANAGEMENT, LP
Sold off
None of the stocks were completely sold off by SR ONE CAPITAL MANAGEMENT, LP
Sector Distribution
SR One Capital Management, LP has about 55.1% of it's holdings in Healthcare sector.
- Healthcare
- Others
| Sector | % |
|---|---|
| Healthcare | 55.1 |
| Others | 41.4 |
| 3.5 |
Market Cap. Distribution
SR One Capital Management, LP has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.
- UNALLOCATED
- MID-CAP
- SMALL-CAP
| Category | % |
|---|---|
| UNALLOCATED | 41.4 |
| MID-CAP | 40 |
| SMALL-CAP | 17.8 |
Stocks belong to which Index?
About 44.2% of the stocks held by SR One Capital Management, LP either belong to S&P 500 or RUSSELL 2000 index.
- Others
- RUSSELL 2000
| Index | % |
|---|---|
| Others | 55.8 |
| RUSSELL 2000 | 44.2 |
SR ONE CAPITAL MANAGEMENT, LP Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of SR ONE CAPITAL MANAGEMENT, LP
SR One Capital Management, LP has 14 stocks in it's portfolio. About 96.5% of the portfolio is in top 10 stocks. proved to be the most loss making stock for the portfolio. ACLX was the most profitable stock for SR One Capital Management, LP last quarter.
$915.44MTotal Value
14.00Positions
14 May, 2026Last Reported
| Expand | Holdingsorted ascending | % Portfolio | Shares Held | $ Value | % Change |
|---|---|---|---|---|---|
 Arcellx, Inc. Arcellx, Inc.ACLX SR ONE CAPITAL MANAGEMENT, LP's holding in Arcellx, Inc. over time | 29.43% | 2,346,630 | $269.44M 29.43% | 0%unchanged 0 percentunchanged | |
 Crispr Therapeutics Ag SR ONE CAPITAL MANAGEMENT, LP's holding in Crispr Therapeutics Ag over time | 10.59% | 2,038,760 | $96.98M 10.59% | 0%unchanged 0 percentunchanged | |
 Design Therapeutics, Inc. SR ONE CAPITAL MANAGEMENT, LP's holding in Design Therapeutics, Inc. over time | 7.59% | 6,526,480 | $69.44M 7.59% | 0%unchanged 0 percentunchanged | |
 Nkarta, Inc. Nkarta, Inc.NKTX SR ONE CAPITAL MANAGEMENT, LP's holding in Nkarta, Inc. over time | 0.77% | 3,333,330 | $7.03M 0.77% | 0%unchanged 0 percentunchanged | |
 Oric Pharmaceuticals, Inc. SR ONE CAPITAL MANAGEMENT, LP's holding in Oric Pharmaceuticals, Inc. over time | 6.39% | 4,514,930 | $58.48M 6.39% | 0%unchanged 0 percentunchanged | |
 Ultragenyx Pharmaceutical Inc. SR ONE CAPITAL MANAGEMENT, LP's holding in Ultragenyx Pharmaceutical Inc. over time | 0.32% | 137,753 | $2.89M 0.32% | 0%unchanged 0 percentunchanged | |
 Ars Pharmaceuticals, Inc. SR ONE CAPITAL MANAGEMENT, LP's holding in Ars Pharmaceuticals, Inc. over time | 3.52% | 4,012,900 | $32.22M 3.52% | 0%unchanged 0 percentunchanged | |
Common Stock Veradermics, Inc.Veradermics, Inc. | 16.57% | 2,401,870 | $151.68M 16.57% | Newnew position | |
Common Stock Zenas Biopharma, IncZenas Biopharma, Inc | 10.76% | 5,037,850 | $98.49M 10.76% | 0%unchanged 0 percentunchanged | |
Common Stock Alumis Inc.Alumis Inc. | 4.72% | 1,959,900 | $43.18M 4.72% | 0%unchanged 0 percentunchanged | |
Common Stock Mineralys Therapeutics Inc.Mineralys Therapeutics Inc. | 4.63% | 1,563,970 | $42.37M 4.63% | 0%unchanged 0 percentunchanged | |
Common Stock Oruka Therapeutics, IncOruka Therapeutics, Inc | 2.31% | 430,330 | $21.11M 2.31% | 0%unchanged 0 percentunchanged | |
Ordinary Shares Oculis Holding AgOculis Holding Ag | 1.86% | 641,022 | $17.04M 1.86% | 0%unchanged 0 percentunchanged | |
Common Shares Engene Holdings Inc.Engene Holdings Inc. | 0.56% | 747,750 | $5.09M 0.56% | 0%unchanged 0 percentunchanged | |