Latest Checkpoint Capital L.P. Stock Portfolio
Checkpoint Capital L.P. Performance:
2025 Q4: 7.22%YTD: 33.77%2024: 11.44%
Performance for 2025 Q4 is 7.22%, and YTD is 33.77%, and 2024 is 11.44%.
About Checkpoint Capital L.P. and 13F Hedge Fund Stock Holdings
On 2026-02-17, the fund reported it's updated stock portfolio. In the 13F Holdings report, Checkpoint Capital L.P. reported an equity portfolio of $320.1 Millions as of 31 Dec, 2025.
The top stock holdings of Checkpoint Capital L.P. are ARGX, RYTM, . The fund has invested 37.3% of it's portfolio in ARGENX SE and 33.2% of portfolio in RHYTHM PHARMACEUTICALS INC.
The fund managers got completely rid off CRINETICS PHARMACEUTICALS IN (CRNX), SEPTERNA INC and STOKE THERAPEUTICS INC (STOK) stocks. They significantly reduced their stock positions in REVOLUTION MEDICINES INC (RVMD) and ARGENX SE (ARGX). The fund showed a lot of confidence in some stocks as they added substantially to CYTOKINETICS INC (CYTK), RHYTHM PHARMACEUTICALS INC (RYTM) and DISC MEDICINE INC.
The top stock holdings of Checkpoint Capital L.P. are ARGX, RYTM, . The fund has invested 37.3% of it's portfolio in ARGENX SE and 33.2% of portfolio in RHYTHM PHARMACEUTICALS INC.
The fund managers got completely rid off CRINETICS PHARMACEUTICALS IN (CRNX), SEPTERNA INC and STOKE THERAPEUTICS INC (STOK) stocks. They significantly reduced their stock positions in REVOLUTION MEDICINES INC (RVMD) and ARGENX SE (ARGX). The fund showed a lot of confidence in some stocks as they added substantially to CYTOKINETICS INC (CYTK), RHYTHM PHARMACEUTICALS INC (RYTM) and DISC MEDICINE INC.
Checkpoint Capital L.P. Annual Return Estimates Vs S&P 500
Our best estimate is that Checkpoint Capital L.P. made a return of 7.22% in the last quarter. In trailing 12 months, it's portfolio return was 33.77%.
- Performance
- S&P 500
New Buys
Additions
| Ticker | % Inc. |
|---|---|
| cytokinetics inc | 343 |
| rhythm pharmaceuticals inc | 29.92 |
| disc medicine inc | 5.35 |
| corcept therapeutics inc | 2.31 |
Additions to existing portfolio by Checkpoint Capital L.P.
Reductions
| Ticker | % Reduced |
|---|---|
| revolution medicines inc | -24.84 |
| argenx se | -5.33 |
Checkpoint Capital L.P. reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| septerna inc | -5,326,200 |
| crinetics pharmaceuticals in | -10,829,000 |
| stoke therapeutics inc | -4,983,150 |
| kymera therapeutics inc | -3,495,050 |
Checkpoint Capital L.P. got rid off the above stocks
Sector Distribution
Checkpoint Capital L.P. has about 50.8% of it's holdings in Healthcare sector.
- Healthcare
- Others
| Sector | % |
|---|---|
| Healthcare | 50.8 |
| Others | 49.2 |
Market Cap. Distribution
Checkpoint Capital L.P. has about 9.3% of it's portfolio invested in the large-cap and mega-cap stocks.
- UNALLOCATED
- MID-CAP
- LARGE-CAP
| Category | % |
|---|---|
| UNALLOCATED | 49.2 |
| MID-CAP | 41.4 |
| LARGE-CAP | 9.3 |
Stocks belong to which Index?
About 50.8% of the stocks held by Checkpoint Capital L.P. either belong to S&P 500 or RUSSELL 2000 index.
- RUSSELL 2000
- Others
| Index | % |
|---|---|
| RUSSELL 2000 | 50.8 |
| Others | 49.2 |
Checkpoint Capital L.P. Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Checkpoint Capital L.P.
Checkpoint Capital L.P. has 6 stocks in it's portfolio. CORT proved to be the most loss making stock for the portfolio. ARGX was the most profitable stock for Checkpoint Capital L.P. last quarter.
Last Reported on: 17 Feb, 2026| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ARGX | argenx se | 37.31 | 142,000 | 119,415,000 | reduced | -5.33 | ||
| CORT | corcept therapeutics inc | 4.36 | 401,395 | 13,968,500 | added | 2.31 | ||
| CRNX | crinetics pharmaceuticals in | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| CYTK | cytokinetics inc | 3.31 | 166,823 | 10,599,900 | added | 343 | ||
| KYMR | kymera therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| RVMD | revolution medicines inc | 9.21 | 370,000 | 29,470,500 | reduced | -24.84 | ||
| RYTM | rhythm pharmaceuticals inc | 33.18 | 992,200 | 106,205,000 | added | 29.92 | ||
| STOK | stoke therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| disc medicine inc | 11.24 | 452,992 | 35,972,100 | added | 5.35 | |||
| septerna inc | 0.00 | 0.00 | 0.00 | sold off | -100 | |||