Latest Exome Asset Management LLC Stock Portfolio

Exome Asset Management LLC Performance:

2025 Q4: 33.94%YTD: 51.08%2024: 8.89%

Performance for 2025 Q4 is 33.94%, and YTD is 51.08%, and 2024 is 8.89%.

About Exome Asset Management LLC and 13F Hedge Fund Stock Holdings

On 2026-02-13, the fund reported it's updated stock portfolio. In the 13F Holdings report, Exome Asset Management LLC reported an equity portfolio of $209.1 Millions as of 31 Dec, 2025.

The top stock holdings of Exome Asset Management LLC are PRAX, COGT, GH. The fund has invested 8.2% of it's portfolio in PRAXIS PRECISION MEDICINES I and 5.2% of portfolio in COGENT BIOSCIENCES INC.

The fund managers got completely rid off 89BIO INC (ETNB), APOGEE THERAPEUTICS INC and CVS HEALTH CORP (CVS) stocks. They significantly reduced their stock positions in TENET HEALTHCARE CORP (THC), NOVABRIDGE BIOSCIENCES (IMAB) and ARROWHEAD PHARMACEUTICALS IN (ARWR). Exome Asset Management LLC opened new stock positions in WAVE LIFE SCIENCES LTD (WVE), ELEVANCE HEALTH INC FORMERLY (ANTX) and JAZZ PHARMACEUTICALS PLC (JAZZ). The fund showed a lot of confidence in some stocks as they added substantially to UNIVERSAL HLTH SVCS INC (UHS), WAYSTAR HLDG CORP and GLAUKOS CORP (GKOS).

Exome Asset Management LLC Annual Return Estimates Vs S&P 500

Our best estimate is that Exome Asset Management LLC made a return of 33.94% in the last quarter. In trailing 12 months, it's portfolio return was 51.08%.

Performance
S&P 500

New Buys

Ticker	$ Bought
wave life sciences ltd	7,165,300
elevance health inc formerly	6,026,300
jazz pharmaceuticals plc	4,503,980
agios pharmaceuticals inc	3,727,560
enliven therapeutics inc	3,423,540
celcuity inc	3,419,980
apellis pharmaceuticals inc	3,412,530
dexcom inc	3,328,260

New stocks bought by Exome Asset Management LLC

Additions

Ticker	% Inc.
universal hlth svcs inc	121
waystar hldg corp	47.06
upstream bio inc	24.8
glaukos corp	15.95
united therapeutics corp del	15.65

Additions to existing portfolio by Exome Asset Management LLC

Reductions

Ticker	% Reduced
tenet healthcare corp	-66.39
novabridge biosciences	-65.3
arrowhead pharmaceuticals in	-52.39
travere therapeutics inc	-43.25
praxis precision medicines i	-43.02
edgewise therapeutics inc	-42.32
bridgebio pharma inc	-39.35
corbus pharmaceuticals hldgs	-39.32

Exome Asset Management LLC reduced stake in above stock

Sold off

Ticker	$ Sold
karyopharm therapeutics inc	-1,633,600
sarepta therapeutics inc	-1,764,410
geron corp	-2,545,940
89bio inc	-4,022,820
moonlake immunotherapeutics	-1,276,860
immunic inc	-153,310
oric pharmaceuticals inc	-1,447,730
syndax pharmaceuticals inc	-1,812,090

Exome Asset Management LLC got rid off the above stocks

Sector Distribution

Exome Asset Management LLC has about 86.1% of it's holdings in Healthcare sector.

Sector	%
Healthcare	86.1
Others	13.9

Market Cap. Distribution

Exome Asset Management LLC has about 32.8% of it's portfolio invested in the large-cap and mega-cap stocks.

Category	%
MID-CAP	39.4
LARGE-CAP	27.7
UNALLOCATED	13.9
SMALL-CAP	7.6
MEGA-CAP	5.1
NANO-CAP	4.1
MICRO-CAP	2

Stocks belong to which Index?

About 50.9% of the stocks held by Exome Asset Management LLC either belong to S&P 500 or RUSSELL 2000 index.

Index	%
Others	49.1
RUSSELL 2000	39.9
S&P 500	11

Top 5 Winners (%)		%
PRAX	praxis precision medicines i	358.0 %
	alumis inc	144.5 %
COGT	cogent biosciences inc	124.4 %
ESTA	establishment labs hldgs inc	77.8 %
ARWR	arrowhead pharmaceuticals in	68.3 %

Top 5 Winners ($)		$
PRAX	praxis precision medicines i	19.4 M
COGT	cogent biosciences inc	7.9 M
GH	guardant health inc	3.9 M
VERA	vera therapeutics inc	3.0 M
BBIO	bridgebio pharma inc	2.6 M

Top 5 Losers (%)		%
CRBP	corbus pharmaceuticals hldgs	-28.6 %
	waystar hldg corp	-11.7 %
THC	tenet healthcare corp	-1.4 %

Top 5 Losers ($)		$
CRBP	corbus pharmaceuticals hldgs	-0.8 M
	waystar hldg corp	-0.3 M
THC	tenet healthcare corp	-0.1 M

Exome Asset Management LLC Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Exome Asset Management LLC

Exome Asset Management LLC has 53 stocks in it's portfolio. About 42.7% of the portfolio is in top 10 stocks. CRBP proved to be the most loss making stock for the portfolio. PRAX was the most profitable stock for Exome Asset Management LLC last quarter.

Last Reported on: 13 Feb, 2026

Ticker	Namesorted ascending	% Portfolio	Shares Held	$ Value	Type	% Change
ABC	cencora inc	0.00	0.00	0.00	sold off	-100

ABUS	arbutus biopharma corp	0.17	75,484	363,078	unchanged	0.00

ADAG	adagene inc	0.96	1,060,220	2,003,820	new

AGIO	agios pharmaceuticals inc	1.78	136,942	3,727,560	new

AKRO	akero therapeutics inc	0.00	0.00	0.00	sold off	-100

ANTX	elevance health inc formerly	2.88	17,191	6,026,300	new

APLS	apellis pharmaceuticals inc	1.63	135,849	3,412,530	new

ARWR	arrowhead pharmaceuticals in	1.58	49,758	3,303,430	reduced	-52.39

AVTX	avalo therapeutics inc	0.00	0.00	0.00	sold off	-100

AZN	astrazeneca plc	2.52	28,362	5,260,650	unchanged	0.00

BBIO	bridgebio pharma inc	2.95	80,723	6,174,500	reduced	-39.35

BLTE	belite bio inc	1.10	14,328	2,291,910	new

CELC	celcuity inc	1.64	34,289	3,419,980	new

CNTA	centessa pharmaceuticals plc	0.00	0.00	0.00	sold off	-100

COGT	cogent biosciences inc	5.19	305,568	10,853,800	reduced	-31.11

CRBP	corbus pharmaceuticals hldgs	0.54	139,543	1,135,880	reduced	-39.32

CTMX	cytomx therapeutics inc	1.52	745,305	3,175,000	unchanged	0.00

CVS	cvs health corp	0.00	0.00	0.00	sold off	-100

CYTK	cytokinetics inc	3.79	124,749	7,926,550	reduced	-12.41

DXCM	dexcom inc	1.59	50,147	3,328,260	new