Latest Exome Asset Management LLC Stock Portfolio
Exome Asset Management LLC Performance:
2025 Q3: 15.39%YTD: 12.8%2024: 8.89%
Performance for 2025 Q3 is 15.39%, and YTD is 12.8%, and 2024 is 8.89%.
About Exome Asset Management LLC and 13F Hedge Fund Stock Holdings
In it's latest 13F Holdings report, Exome Asset Management LLC reported an equity portfolio of $165.1 Millions as of 30 Sep, 2025.
The top stock holdings of Exome Asset Management LLC are IONS, CYTK, BBIO. The fund has invested 5.2% of it's portfolio in IONIS PHARMACEUTICALS INC and 4.7% of portfolio in CYTOKINETICS INC.
The fund managers got completely rid off SCHOLAR ROCK HLDG CORP (SRRK), VERASTEM INC (VSTM) and DYNE THERAPEUTICS INC (DYN) stocks. They significantly reduced their stock positions in REPLIMUNE GROUP INC (REPL), FULCRUM THERAPEUTICS INC (FULC) and SYNDAX PHARMACEUTICALS INC (SNDX). Exome Asset Management LLC opened new stock positions in I MAB (IMAB), ASTRAZENECA PLC and ARROWHEAD PHARMACEUTICALS IN (ARWR). The fund showed a lot of confidence in some stocks as they added substantially to LIQUIDIA CORPORATION (LQDA), VERA THERAPEUTICS INC (VERA) and PRAXIS PRECISION MEDICINES I (PRAX).
The top stock holdings of Exome Asset Management LLC are IONS, CYTK, BBIO. The fund has invested 5.2% of it's portfolio in IONIS PHARMACEUTICALS INC and 4.7% of portfolio in CYTOKINETICS INC.
The fund managers got completely rid off SCHOLAR ROCK HLDG CORP (SRRK), VERASTEM INC (VSTM) and DYNE THERAPEUTICS INC (DYN) stocks. They significantly reduced their stock positions in REPLIMUNE GROUP INC (REPL), FULCRUM THERAPEUTICS INC (FULC) and SYNDAX PHARMACEUTICALS INC (SNDX). Exome Asset Management LLC opened new stock positions in I MAB (IMAB), ASTRAZENECA PLC and ARROWHEAD PHARMACEUTICALS IN (ARWR). The fund showed a lot of confidence in some stocks as they added substantially to LIQUIDIA CORPORATION (LQDA), VERA THERAPEUTICS INC (VERA) and PRAXIS PRECISION MEDICINES I (PRAX).
Exome Asset Management LLC Annual Return Estimates Vs S&P 500
Our best estimate is that Exome Asset Management LLC made a return of 15.39% in the last quarter. In trailing 12 months, it's portfolio return was 10.83%.
New Buys
| Ticker | $ Bought |
|---|---|
| i mab | 5,441,700 |
| astrazeneca plc | 4,269,550 |
| apogee therapeutics inc | 3,750,510 |
| arrowhead pharmaceuticals in | 3,604,450 |
| cvs health corp | 3,287,000 |
| united therapeutics corp del | 2,785,650 |
| akero therapeutics inc | 2,781,330 |
| immunovant inc | 2,556,990 |
New stocks bought by Exome Asset Management LLC
Additions
| Ticker | % Inc. |
|---|---|
| liquidia corporation | 359 |
| vera therapeutics inc | 103 |
| praxis precision medicines i | 72.87 |
| eli lilly & co | 68.03 |
| edgewise therapeutics inc | 39.34 |
| cytokinetics inc | 22.97 |
| 89bio inc | 17.24 |
| soleno therapeutics inc | 16.34 |
Additions to existing portfolio by Exome Asset Management LLC
Reductions
| Ticker | % Reduced |
|---|---|
| replimune group inc | -81.5 |
| fulcrum therapeutics inc | -77.8 |
| syndax pharmaceuticals inc | -61.8 |
| gossamer bio inc | -58.86 |
| centessa pharmaceuticals plc | -47.27 |
| geron corp | -45.57 |
| tenet healthcare corp | -32.96 |
| universal hlth svcs inc | -21.24 |
Exome Asset Management LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| verastem inc | -2,489,580 |
| regenxbio inc | -1,855,950 |
| compass pathways plc | -597,923 |
| vyne therapeutics inc | -344,801 |
| dyne therapeutics inc | -1,865,280 |
| biocryst pharmaceuticals inc | -1,549,030 |
| eledon pharmaceuticals inc | -309,333 |
| elevation oncology inc | -40,511 |
Exome Asset Management LLC got rid off the above stocks
Sector Distribution
Exome Asset Management LLC has about 83.6% of it's holdings in Healthcare sector.
| Sector | % |
|---|---|
| Healthcare | 83.6 |
| Others | 16.4 |
Market Cap. Distribution
Exome Asset Management LLC has about 16.9% of it's portfolio invested in the large-cap and mega-cap stocks.
| Category | % |
|---|---|
| MID-CAP | 35.9 |
| SMALL-CAP | 28.5 |
| UNALLOCATED | 15.1 |
| LARGE-CAP | 12.9 |
| MEGA-CAP | 4 |
| MICRO-CAP | 2.6 |
Stocks belong to which Index?
About 52.3% of the stocks held by Exome Asset Management LLC either belong to S&P 500 or RUSSELL 2000 index.
| Index | % |
|---|---|
| Others | 47.7 |
| RUSSELL 2000 | 43 |
| S&P 500 | 9.3 |
Exome Asset Management LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Exome Asset Management LLC
Exome Asset Management LLC has 52 stocks in it's portfolio. About 37.2% of the portfolio is in top 10 stocks. REPL proved to be the most loss making stock for the portfolio. COGT was the most profitable stock for Exome Asset Management LLC last quarter.
Last Reported on: 14 Nov, 2025| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ABC | cencora inc | 1.14 | 6,000 | 1,875,180 | new | |||
| ABUS | arbutus biopharma corp | 0.21 | 75,484 | 342,697 | unchanged | 0.00 | ||
| AKRO | akero therapeutics inc | 1.68 | 58,579 | 2,781,330 | new | |||
| ANAB | anaptysbio inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| APLS | apellis pharmaceuticals inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ARWR | arrowhead pharmaceuticals in | 2.18 | 104,507 | 3,604,450 | new | |||
| AVTX | avalo therapeutics inc | 0.77 | 100,036 | 1,271,460 | new | |||
| BBIO | bridgebio pharma inc | 4.19 | 133,087 | 6,912,540 | reduced | -14.43 | ||
| BCRX | biocryst pharmaceuticals inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| CLDX | celldex therapeutics inc new | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| CMPS | compass pathways plc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| CNTA | centessa pharmaceuticals plc | 1.29 | 88,024 | 2,134,580 | reduced | -47.27 | ||
| COGT | cogent biosciences inc | 3.86 | 443,547 | 6,369,340 | reduced | -16.88 | ||
| CRBP | corbus pharmaceuticals hldgs | 1.76 | 229,962 | 2,909,020 | reduced | -17.08 | ||
| CRNX | crinetics pharmaceuticals in | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| CTMX | cytomx therapeutics inc | 1.44 | 745,305 | 2,377,520 | new | |||
| CVS | cvs health corp | 1.99 | 43,600 | 3,287,000 | new | |||
| CYTK | cytokinetics inc | 4.74 | 142,417 | 7,827,240 | added | 22.97 | ||
| DYN | dyne therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ELDN | eledon pharmaceuticals inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||