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Latest Exome Asset Management LLC Stock Portfolio

$193Million– No. of Holdings #45

Exome Asset Management LLC Performance:
2026 Q1: 4.37%YTD: 4.37%2025: 51.08%
Performance for 2026 Q1 is 4.37%, and YTD is 4.37%, and 2025 is 51.08%.

About Exome Asset Management LLC and 13F Hedge Fund Stock Holdings

On 2026-05-15, the fund reported it's updated stock portfolio. In the 13F Holdings report, Exome Asset Management LLC reported an equity portfolio of $193.3 Millions as of 31 Mar, 2026.

The top stock holdings of Exome Asset Management LLC are PRAX, COGT, . The fund has invested 7.6% of it's portfolio in PRAXIS PRECISION MEDICINES I and 5.5% of portfolio in COGENT BIOSCIENCES INC.

The fund managers got completely rid off WAVE LIFE SCIENCES LTD (WVE), ASTRAZENECA PLC (AZN) and JAZZ PHARMACEUTICALS PLC (JAZZ) stocks. They significantly reduced their stock positions in LIQUIDIA CORPORATION (LQDA), APELLIS PHARMACEUTICALS INC (APLS) and GLAUKOS CORP (GKOS). Exome Asset Management LLC opened new stock positions in INSMED INC (INSM), MOONLAKE IMMUNOTHERAPEUTICS (MLTX) and RHYTHM PHARMACEUTICALS INC (RYTM). The fund showed a lot of confidence in some stocks as they added substantially to UNITEDHEALTH GROUP INC (UNH), CORBUS PHARMACEUTICALS HLDGS (CRBP) and VERASTEM INC (VSTM).
Exome Asset Management LLC Equity Portfolio Value
Last Reported on: 15 May, 2026

Exome Asset Management LLC Annual Return Estimates Vs S&P 500

Our best estimate is that Exome Asset Management LLC made a return of 4.37% in the last quarter. In trailing 12 months, it's portfolio return was 70.36%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
insmed inc4,357,970
moonlake immunotherapeutics4,014,610
rhythm pharmaceuticals inc3,529,330
boston scientific corp3,033,770
alkermes plc2,973,880
monte rosa therapeutics inc2,952,510
crescent biopharma inc.2,814,120
relay therapeutics inc2,769,100
New stocks bought by Exome Asset Management LLC

Additions

Ticker% Inc.
unitedhealth group inc120
corbus pharmaceuticals hldgs67.79
verastem inc58.48
novabridge biosciences15.49
Additions to existing portfolio by Exome Asset Management LLC

Reductions

Ticker% Reduced
liquidia corporation-49.76
apellis pharmaceuticals inc-37.05
glaukos corp-33.67
adagene inc-30.5
cytomx therapeutics inc.-30.03
nextcure inc-30.00
penumbra inc-30.00
praxis precision medicines i-21.77
Exome Asset Management LLC reduced stake in above stock

Sold off

Ticker$ Sold
ironwood pharmaceuticals inc-2,185,550
inhibikase therapeutics inc-1,230,000
gossamer bio inc-1,400,270
wave life sciences ltd-7,165,300
karyopharm therapeutics inc-2,175,180
immunovant inc-4,032,170
edgewise therapeutics inc-2,482,640
fulcrum therapeutics inc-1,041,140
Exome Asset Management LLC got rid off the above stocks

Sector Distribution

Exome Asset Management LLC has about 84.6% of it's holdings in Healthcare sector.

  • Healthcare
  • Others
Sector%
Healthcare84.6
Others15.4

Market Cap. Distribution

Exome Asset Management LLC has about 30.1% of it's portfolio invested in the large-cap and mega-cap stocks.

  • MID-CAP
  • LARGE-CAP
  • UNALLOCATED
  • SMALL-CAP
  • MEGA-CAP
  • NANO-CAP
  • MICRO-CAP
Category%
MID-CAP35.1
LARGE-CAP24.3
UNALLOCATED15.4
SMALL-CAP12.6
MEGA-CAP5.8
NANO-CAP3.5
MICRO-CAP3.3

Stocks belong to which Index?

About 47.1% of the stocks held by Exome Asset Management LLC either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • RUSSELL 2000
  • S&P 500
Index%
Others53
RUSSELL 200037.7
S&P 5009.4
Top 5 Winners (%)%
enliven therapeutics inc
153.8 %
alumis inc
122.9 %
ADAG
adagene inc
91.0 %
APLS
apellis pharmaceuticals inc
49.0 %
TXG
10x genomics inc
29.3 %
Top 5 Winners ($)$
enliven therapeutics inc
5.3 M
alumis inc
3.5 M
ADAG
adagene inc
1.8 M
APLS
apellis pharmaceuticals inc
1.7 M
PRAX
praxis precision medicines i
1.4 M
Top 5 Losers (%)%
IMAB
novabridge biosciences
-36.6 %
VSTM
verastem inc
-27.1 %
PALI
palisade bio inc
-22.9 %
ESTA
establishment labs hldgs inc
-22.1 %
NXTC
nextcure inc
-22.0 %
Top 5 Losers ($)$
VSTM
verastem inc
-1.3 M
VERA
vera therapeutics inc
-1.2 M
LLY
eli lilly & co
-1.2 M
ANTX
elevance health inc formerly
-0.9 M
GH
guardant health inc
-0.9 M

Exome Asset Management LLC Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Exome Asset Management LLC

Exome Asset Management LLC has 45 stocks in it's portfolio. About 40.8% of the portfolio is in top 10 stocks. VSTM proved to be the most loss making stock for the portfolio. was the most profitable stock for Exome Asset Management LLC last quarter.

Last Reported on: 15 May, 2026
TickerNamesorted ascending% PortfolioShares Held$ ValueType% ChangeOptions