Latest TANG CAPITAL MANAGEMENT LLC Stock Portfolio
$1.97Billion– No. of Holdings #51
TANG CAPITAL MANAGEMENT LLC Performance:
2026 Q1: 1.21%YTD: 1.21%2025: 36.74%
Performance for 2026 Q1 is 1.21%, and YTD is 1.21%, and 2025 is 36.74%.
About TANG CAPITAL MANAGEMENT LLC and 13F Hedge Fund Stock Holdings
On 2026-05-15, the fund reported it's updated stock portfolio. In the 13F Holdings report, TANG CAPITAL MANAGEMENT LLC reported an equity portfolio of $2 Billions as of 31 Mar, 2026.
The top stock holdings of TANG CAPITAL MANAGEMENT LLC are AUPH, CELC, MIRM. The fund has invested 9.2% of it's portfolio in AURINIA PHARMACEUTICALS INC and 6.1% of portfolio in CELCUITY INC.
The fund managers got completely rid off AVIDITY BIOSCIENCES INC (RNA), VERTEX PHARMACEUTICALS INC (VRTX) and TRAVERE THERAPEUTICS INC (TVTX) stocks. They significantly reduced their stock positions in MODERNA INC (MRNA), ERASCA INC (ERAS) and ALTIMMUNE INC (ALT). TANG CAPITAL MANAGEMENT LLC opened new stock positions in COMPASS PATHWAYS PLC (CMPS), JANUX THERAPEUTICS INC (JANX) and AGIOS PHARMACEUTICALS INC (AGIO). The fund showed a lot of confidence in some stocks as they added substantially to CORCEPT THERAPEUTICS INC (CORT), STATE STR SPDR S&P 500 ETF T (SPY) and INSMED INC (INSM).
The top stock holdings of TANG CAPITAL MANAGEMENT LLC are AUPH, CELC, MIRM. The fund has invested 9.2% of it's portfolio in AURINIA PHARMACEUTICALS INC and 6.1% of portfolio in CELCUITY INC.
The fund managers got completely rid off AVIDITY BIOSCIENCES INC (RNA), VERTEX PHARMACEUTICALS INC (VRTX) and TRAVERE THERAPEUTICS INC (TVTX) stocks. They significantly reduced their stock positions in MODERNA INC (MRNA), ERASCA INC (ERAS) and ALTIMMUNE INC (ALT). TANG CAPITAL MANAGEMENT LLC opened new stock positions in COMPASS PATHWAYS PLC (CMPS), JANUX THERAPEUTICS INC (JANX) and AGIOS PHARMACEUTICALS INC (AGIO). The fund showed a lot of confidence in some stocks as they added substantially to CORCEPT THERAPEUTICS INC (CORT), STATE STR SPDR S&P 500 ETF T (SPY) and INSMED INC (INSM).
TANG CAPITAL MANAGEMENT LLC Equity Portfolio Value
Last Reported on: 15 May, 2026
TANG CAPITAL MANAGEMENT LLC Annual Return Estimates Vs S&P 500
Our best estimate is that TANG CAPITAL MANAGEMENT LLC made a return of 1.21% in the last quarter. In trailing 12 months, it's portfolio return was 50.28%.
- Performance
- S&P 500
New Buys
| Ticker | $ Bought |
|---|---|
| compass pathways plc | 22,132,200 |
| janux therapeutics inc | 6,950,000 |
| agios pharmaceuticals inc | 3,383,000 |
| lexicon pharmaceuticals inc | 623,532 |
New stocks bought by TANG CAPITAL MANAGEMENT LLC
Additions
| Ticker | % Inc. |
|---|---|
| corcept therapeutics inc | 856 |
| state str spdr s&p 500 etf t | 460 |
| insmed inc | 333 |
| capricor therapeutics inc | 99.99 |
| ani pharmaceuticals inc | 46.96 |
| crescent biopharma inc. | 32.97 |
| precigen inc | 14.24 |
| aurinia pharmaceuticals inc | 7.94 |
Additions to existing portfolio by TANG CAPITAL MANAGEMENT LLC
Reductions
| Ticker | % Reduced |
|---|---|
| moderna inc | -85.57 |
| erasca inc | -77.78 |
| altimmune inc | -68.75 |
| evolus inc | -61.22 |
| abeona therapeutics inc | -60.00 |
| neumora therapeutics inc. | -54.52 |
| lenz therapeutics inc | -47.86 |
| coherus oncology inc | -30.75 |
TANG CAPITAL MANAGEMENT LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| ventyx biosciences inc | -25,410,400 |
| immunitybio inc | -4,620,000 |
| teladoc health inc | -9,800,000 |
| verastem inc | -8,258,930 |
| avidity biosciences inc | -64,917,000 |
| biocryst pharmaceuticals inc | -6,240,000 |
| travere therapeutics inc | -26,747,000 |
| dynavax technologies corp | -8,556,800 |
TANG CAPITAL MANAGEMENT LLC got rid off the above stocks
Sector Distribution
TANG CAPITAL MANAGEMENT LLC has about 74.5% of it's holdings in Healthcare sector.
- Healthcare
- Others
| Sector | % |
|---|---|
| Healthcare | 74.5 |
| Others | 25.5 |
Market Cap. Distribution
TANG CAPITAL MANAGEMENT LLC has about 2.7% of it's portfolio invested in the large-cap and mega-cap stocks.
- SMALL-CAP
- MID-CAP
- UNALLOCATED
- LARGE-CAP
- MICRO-CAP
| Category | % |
|---|---|
| SMALL-CAP | 36.7 |
| MID-CAP | 33 |
| UNALLOCATED | 25.5 |
| LARGE-CAP | 2.7 |
| MICRO-CAP | 1.9 |
Stocks belong to which Index?
About 62.2% of the stocks held by TANG CAPITAL MANAGEMENT LLC either belong to S&P 500 or RUSSELL 2000 index.
- RUSSELL 2000
- Others
| Index | % |
|---|---|
| RUSSELL 2000 | 62.2 |
| Others | 37.2 |
TANG CAPITAL MANAGEMENT LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of TANG CAPITAL MANAGEMENT LLC
TANG CAPITAL MANAGEMENT LLC has 51 stocks in it's portfolio. About 57.9% of the portfolio is in top 10 stocks. VRDN proved to be the most loss making stock for the portfolio. AGLE was the most profitable stock for TANG CAPITAL MANAGEMENT LLC last quarter.
Last Reported on: 15 May, 2026| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ABEO | abeona therapeutics inc | 0.09 | 400,000 | 1,792,000 | reduced | -60.00 | ||
| ACAD | acadia pharmaceuticals inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ACET | adicet bio inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| AGIO | agios pharmaceuticals inc | 0.17 | 100,000 | 3,383,000 | new | |||
| AGLE | spyre therapeutics inc | 4.85 | 1,892,200 | 95,442,600 | unchanged | 0.00 | ||
| ALT | altimmune inc | 0.10 | 666,022 | 2,051,350 | reduced | -68.75 | ||
| ANAB | anaptysbio inc | 3.75 | 1,996,310 | 73,810,600 | reduced | -0.09 | ||
| ANIP | ani pharmaceuticals inc | 2.76 | 707,500 | 54,406,800 | added | 46.96 | ||
| ARE | alexandria real estate eq in | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ARVN | arvinas inc | 0.29 | 538,658 | 5,709,780 | reduced | -5.45 | ||
| AUPH | aurinia pharmaceuticals inc | 9.20 | 12,229,500 | 181,241,000 | added | 7.94 | ||
| AVIR | atea pharmaceuticals inc | 1.32 | 4,814,700 | 25,903,100 | unchanged | 0.00 | ||
| BCRX | biocryst pharmaceuticals inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| BIIB | biogen inc | 0.33 | 35,000 | 6,416,550 | unchanged | 0.00 | ||
| BMY | bristol-myers squibb co | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| BNTX | biontech se | 2.12 | 470,000 | 41,773,600 | unchanged | 0.00 | ||
| CAPR | capricor therapeutics inc | 5.25 | 3,399,900 | 103,357,000 | added | 99.99 | ||
| CELC | celcuity inc | 6.09 | 1,050,000 | 119,847,000 | unchanged | 0.00 | ||
| CHRS | coherus oncology inc | 0.16 | 1,886,750 | 3,188,600 | reduced | -30.75 | ||
| CMPS | compass pathways plc | 1.12 | 4,002,200 | 22,132,200 | new | |||