Latest TANG CAPITAL MANAGEMENT LLC Stock Portfolio
TANG CAPITAL MANAGEMENT LLC Performance:
2025 Q3: 14.54%YTD: 9.82%2024: -1.07%
Performance for 2025 Q3 is 14.54%, and YTD is 9.82%, and 2024 is -1.07%.
About TANG CAPITAL MANAGEMENT LLC and 13F Hedge Fund Stock Holdings
In it's latest 13F Holdings report, TANG CAPITAL MANAGEMENT LLC reported an equity portfolio of $2.6 Billions as of 30 Sep, 2025.
The top stock holdings of TANG CAPITAL MANAGEMENT LLC are TARS, , AUPH. The fund has invested 5.6% of it's portfolio in TARSUS PHARMACEUTICALS INC and 5.5% of portfolio in GALAPAGOS NV.
The fund managers got completely rid off ITEOS THERAPEUTICS INC (ITOS), CARGO THERAPEUTICS INC and ELANCO ANIMAL HEALTH INC (ELAN) stocks. They significantly reduced their stock positions in CASSAVA SCIENCES INC COMMON STOCK (SAVA), BOEING CO (BA) and METTLER-TOLEDO INTERNATIONAL (MTD). TANG CAPITAL MANAGEMENT LLC opened new stock positions in CELCUITY INC (CELC), PRECIGEN INC (PGEN) and IDEAYA BIOSCIENCES INC (IDYA). The fund showed a lot of confidence in some stocks as they added substantially to NIKE INC (NKE), FENNEC PHARMACEUTICALS INC (FENC) and CRESCENT BIOPHARMA INC..
The top stock holdings of TANG CAPITAL MANAGEMENT LLC are TARS, , AUPH. The fund has invested 5.6% of it's portfolio in TARSUS PHARMACEUTICALS INC and 5.5% of portfolio in GALAPAGOS NV.
The fund managers got completely rid off ITEOS THERAPEUTICS INC (ITOS), CARGO THERAPEUTICS INC and ELANCO ANIMAL HEALTH INC (ELAN) stocks. They significantly reduced their stock positions in CASSAVA SCIENCES INC COMMON STOCK (SAVA), BOEING CO (BA) and METTLER-TOLEDO INTERNATIONAL (MTD). TANG CAPITAL MANAGEMENT LLC opened new stock positions in CELCUITY INC (CELC), PRECIGEN INC (PGEN) and IDEAYA BIOSCIENCES INC (IDYA). The fund showed a lot of confidence in some stocks as they added substantially to NIKE INC (NKE), FENNEC PHARMACEUTICALS INC (FENC) and CRESCENT BIOPHARMA INC..
TANG CAPITAL MANAGEMENT LLC Annual Return Estimates Vs S&P 500
Our best estimate is that TANG CAPITAL MANAGEMENT LLC made a return of 14.54% in the last quarter. In trailing 12 months, it's portfolio return was 3.63%.
New Buys
| Ticker | $ Bought |
|---|---|
| celcuity inc | 56,810,000 |
| precigen inc | 40,796,000 |
| ideaya biosciences inc | 10,884,000 |
| pmv pharmaceuticals, inc. | 6,699,280 |
| crispr therapeutics ag | 6,481,000 |
| vor biopharma inc | 2,436,000 |
| gossamer bio inc | 2,104,000 |
| cognition therapeutics inc | 1,620,000 |
New stocks bought by TANG CAPITAL MANAGEMENT LLC
Additions
| Ticker | % Inc. |
|---|---|
| nike inc | 2,577 |
| fennec pharmaceuticals inc | 1,530 |
| crescent biopharma inc. | 1,255 |
| vertex pharmaceuticals inc | 700 |
| centessa pharmaceuticals plc | 300 |
| ionis pharmaceuticals inc | 266 |
| janux therapeutics inc | 250 |
| verastem inc | 192 |
Additions to existing portfolio by TANG CAPITAL MANAGEMENT LLC
Reductions
| Ticker | % Reduced |
|---|---|
| cassava sciences inc common stock | -97.05 |
| boeing co | -96.95 |
| mettler-toledo international | -89.9 |
| metagenomi inc | -86.00 |
| iovance biotherapeutics inc | -69.79 |
| bolt biotherapeutics inc | -59.92 |
| sanofi | -50.00 |
| ge vernova inc | -43.08 |
TANG CAPITAL MANAGEMENT LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| hillevax inc | -9,790,800 |
| essa pharma inc | -7,310,000 |
| iteos therapeutics inc | -38,152,100 |
| alx oncology hldgs inc | -1,311,000 |
| cargo therapeutics inc | -12,605,700 |
| applied therapeutics inc | -755,403 |
| third harmonic bio inc | -5,048,420 |
| elanco animal health inc | -11,425,400 |
TANG CAPITAL MANAGEMENT LLC got rid off the above stocks
Sector Distribution
TANG CAPITAL MANAGEMENT LLC has about 75.5% of it's holdings in Healthcare sector.
| Sector | % |
|---|---|
| Healthcare | 75.5 |
| Others | 19.6 |
| Consumer Cyclical | 1.6 |
| Technology | 1.2 |
Market Cap. Distribution
TANG CAPITAL MANAGEMENT LLC has about 9.7% of it's portfolio invested in the large-cap and mega-cap stocks.
| Category | % |
|---|---|
| SMALL-CAP | 43.3 |
| UNALLOCATED | 22.8 |
| MID-CAP | 15.9 |
| MICRO-CAP | 8.1 |
| LARGE-CAP | 7 |
| MEGA-CAP | 2.7 |
Stocks belong to which Index?
About 63.3% of the stocks held by TANG CAPITAL MANAGEMENT LLC either belong to S&P 500 or RUSSELL 2000 index.
| Index | % |
|---|---|
| RUSSELL 2000 | 56 |
| Others | 36.6 |
| S&P 500 | 7.3 |
TANG CAPITAL MANAGEMENT LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of TANG CAPITAL MANAGEMENT LLC
TANG CAPITAL MANAGEMENT LLC has 194 stocks in it's portfolio. About 36.7% of the portfolio is in top 10 stocks. REPL proved to be the most loss making stock for the portfolio. TARS was the most profitable stock for TANG CAPITAL MANAGEMENT LLC last quarter.
Last Reported on: 14 Nov, 2025| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| AAT | american assets tr inc | 0.04 | 50,000 | 1,016,000 | unchanged | 0.00 | ||
| ABCL | abcellera biologics inc | 0.50 | 2,600,000 | 13,078,000 | unchanged | 0.00 | ||
| ACAD | acadia pharmaceuticals inc | 1.23 | 1,500,000 | 32,010,000 | unchanged | 0.00 | ||
| ACET | adicet bio inc | 0.26 | 8,223,610 | 6,662,770 | unchanged | 0.00 | ||
| ADGI | invivyd inc | 0.02 | 400,000 | 440,000 | unchanged | 0.00 | ||
| ADMA | adma biologics inc | 0.59 | 1,050,000 | 15,393,000 | unchanged | 0.00 | ||
| AGLE | spyre therapeutics inc | 2.06 | 3,200,000 | 53,632,000 | unchanged | 0.00 | ||
| ALGS | aligos therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ALL | allstate corp | 0.02 | 2,700 | 579,611 | reduced | -39.84 | ||
| ALT | altimmune inc | 0.31 | 2,131,310 | 8,035,030 | reduced | -22.5 | ||
| ALXO | alx oncology hldgs inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| AMLX | amylyx pharmaceuticals inc | 0.05 | 100,000 | 1,359,000 | unchanged | 0.00 | ||
| AMZN | amazon com inc | 0.02 | 2,583 | 567,132 | reduced | -40.13 | ||
| ANAB | anaptysbio inc | 1.57 | 1,333,640 | 40,836,000 | added | 0.21 | ||
| ANIP | ani pharmaceuticals inc | 1.12 | 317,500 | 29,083,000 | unchanged | 0.00 | ||
| APLT | applied therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ARE | alexandria real estate eq in | 0.13 | 40,000 | 3,333,600 | unchanged | 0.00 | ||
| ARVN | arvinas inc | 0.46 | 1,393,800 | 11,875,200 | unchanged | 0.00 | ||
| ATHA | athira pharma inc | 0.01 | 59,998 | 248,392 | new | |||
| ATHA | athira pharma inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||