Latest Flagship Pioneering Inc. Stock Portfolio
Flagship Pioneering Inc. Performance:
2025 Q4: 10.74%YTD: 5.21%2024: -56.27%
Performance for 2025 Q4 is 10.74%, and YTD is 5.21%, and 2024 is -56.27%.
About Flagship Pioneering Inc. and 13F Hedge Fund Stock Holdings
On 2026-02-17, the fund reported it's updated stock portfolio. In the 13F Holdings report, Flagship Pioneering, LLC reported an equity portfolio of $324 Millions as of 31 Dec, 2025.
The top stock holdings of Flagship Pioneering, LLC are MRNA, SANA, FHTX. The fund has invested 42.2% of it's portfolio in MODERNA INC and 31.4% of portfolio in SANA BIOTECHNOLOGY INC.
The top stock holdings of Flagship Pioneering, LLC are MRNA, SANA, FHTX. The fund has invested 42.2% of it's portfolio in MODERNA INC and 31.4% of portfolio in SANA BIOTECHNOLOGY INC.
Flagship Pioneering Inc. Annual Return Estimates Vs S&P 500
Our best estimate is that Flagship Pioneering, LLC made a return of 10.74% in the last quarter. In trailing 12 months, it's portfolio return was 5.21%.
- Performance
- S&P 500
New Buys
Additions
Reductions
Sold off
Sector Distribution
Flagship Pioneering, LLC has about 100% of it's holdings in Healthcare sector.
- Healthcare
| Sector | % |
|---|---|
| Healthcare | 100 |
Market Cap. Distribution
Flagship Pioneering, LLC has about 42.2% of it's portfolio invested in the large-cap and mega-cap stocks.
- SMALL-CAP
- LARGE-CAP
- MICRO-CAP
| Category | % |
|---|---|
| SMALL-CAP | 52.5 |
| LARGE-CAP | 42.2 |
| MICRO-CAP | 5.3 |
Stocks belong to which Index?
About 100% of the stocks held by Flagship Pioneering, LLC either belong to S&P 500 or RUSSELL 2000 index.
- RUSSELL 2000
- S&P 500
| Index | % |
|---|---|
| RUSSELL 2000 | 57.8 |
| S&P 500 | 42.2 |
Flagship Pioneering Inc. Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Flagship Pioneering Inc.
Flagship Pioneering, LLC has 4 stocks in it's portfolio. MCRB proved to be the most loss making stock for the portfolio. MRNA was the most profitable stock for Flagship Pioneering, LLC last quarter.
Last Reported on: 17 Feb, 2026| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| FHTX | foghorn therapeutics inc | 21.12 | 12,674,100 | 68,440,200 | unchanged | 0.00 | ||
| MCRB | seres therapeutics inc | 5.32 | 1,155,850 | 17,236,400 | unchanged | 0.00 | ||
| MRNA | moderna inc | 42.16 | 4,632,150 | 136,602,000 | unchanged | 0.00 | ||
| SANA | sana biotechnology inc | 31.40 | 25,001,900 | 101,758,000 | unchanged | 0.00 | ||