Latest Flagship Pioneering Inc. Stock Portfolio

$1.16Billion– No. of Holdings #5

Flagship Pioneering Inc. Performance:
2026 Q1: 4.89%YTD: 4.89%2025: 5.21%

Performance for 2026 Q1 is 4.89%, and YTD is 4.89%, and 2025 is 5.21%.

About Flagship Pioneering Inc. and 13F Hedge Fund Stock Holdings

On 2026-05-15, the fund reported it's updated stock portfolio. In the 13F Holdings report, Flagship Pioneering, LLC reported an equity portfolio of $1.2 Billions as of 31 Mar, 2026.

The top stock holdings of Flagship Pioneering, LLC are , MRNA, SANA. The fund has invested 67.4% of it's portfolio in GENERATE BIOMEDICINES INC and 20.3% of portfolio in MODERNA INC.

Flagship Pioneering, LLC opened new stock positions in GENERATE BIOMEDICINES INC.
Flagship Pioneering Inc. Equity Portfolio Value
Last Reported on: 15 May, 2026

Flagship Pioneering Inc. Annual Return Estimates Vs S&P 500

Our best estimate is that Flagship Pioneering, LLC made a return of 4.89% in the last quarter. In trailing 12 months, it's portfolio return was 46.25%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
generate biomedicines inc783,414,000

New stocks bought by Flagship Pioneering Inc.

Additions

No additions were made to existing positions by Flagship Pioneering Inc.

Reductions

None of the existing positions were reduced by Flagship Pioneering Inc.

Sold off

None of the stocks were completely sold off by Flagship Pioneering Inc.

Sector Distribution

Flagship Pioneering, LLC has about 67.4% of it's holdings in Others sector.

  • Others
  • Healthcare
Sector%
Others67.4
Healthcare32.6

Market Cap. Distribution

Flagship Pioneering, LLC has about 20.3% of it's portfolio invested in the large-cap and mega-cap stocks.

  • UNALLOCATED
  • LARGE-CAP
  • SMALL-CAP
Category%
UNALLOCATED67.4
LARGE-CAP20.3
SMALL-CAP11.4

Stocks belong to which Index?

About 32.6% of the stocks held by Flagship Pioneering, LLC either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • S&P 500
  • RUSSELL 2000
Index%
Others67.4
S&P 50020.3
RUSSELL 200012.3
Top 5 Winners (%)%
MRNA
moderna inc
72.3 %
Top 5 Winners ($)$
MRNA
moderna inc
98.7 M
Top 5 Losers (%)%
MCRB
seres therapeutics inc
-40.5 %
SANA
sana biotechnology inc
-29.2 %
FHTX
foghorn therapeutics inc
-11.5 %
Top 5 Losers ($)$
SANA
sana biotechnology inc
-29.8 M
FHTX
foghorn therapeutics inc
-7.9 M
MCRB
seres therapeutics inc
-7.0 M

Flagship Pioneering Inc. Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Flagship Pioneering Inc.

Flagship Pioneering, LLC has 5 stocks in it's portfolio. SANA proved to be the most loss making stock for the portfolio. MRNA was the most profitable stock for Flagship Pioneering, LLC last quarter.

Last Reported on: 15 May, 2026
TickerNamesorted ascending% PortfolioShares Held$ ValueType% ChangeOptions