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Latest Stonepine Capital Management, LLC Stock Portfolio

$177Million | No. of Holdings #72

Stonepine Capital Management, LLC Performance

2026 Q2+4.65%
YTD-7.47%
2025-31.98%

About Stonepine Capital Management, LLC and 13F Hedge Fund Stock Holdings

Stonepine Capital Management, LLC is a hedge fund based in Bend, OR. On 2026-08-17, the fund reported it's updated stock portfolio. In the 13F Holdings report, Stonepine Capital Management, LLC reported an equity portfolio of $177.3 Millions as of 30 Jun, 2026. <br><br> The top stock holdings of Stonepine Capital Management, LLC are VSTM, EOLS, TENX. The fund has invested 7.2% of it's portfolio in VERASTEM INC and 6.2% of portfolio in EVOLUS INC. <br><br> The fund managers got completely rid off XOMA ROYALTY CORPORATION (XOMA), SURROZEN INC (SRZN) and VERRICA PHARMACEUTICALS INC (VRCA) stocks. They significantly reduced their stock positions in BOUNDLESS BIO INC, CODEXIS INC (CDXS) and COMPUGEN LTD (CGEN). Stonepine Capital Management, LLC opened new stock positions in ELOXX PHARMACEUTICALS INC (ELOX), INDIVIOR PHARMACEUTICALS INC and SPRUCE BIOSCIENCES INC (SPRB). The fund showed a lot of confidence in some stocks as they added substantially to CABALETTA BIO INC (CABA), EDESA BIOTECH INC (EDSA) and SATELLOS BIOSCIENCE INC.
Stonepine Capital Management, LLC Equity Portfolio Value
Last Reported on: 17 Aug, 2026
$177Million
  as of Aug 17, 2026

Stonepine Capital Management, LLC Annual Return Estimates Vs S&P 500

Our best estimate is that Stonepine Capital Management, LLC made a return of 4.65% in the last quarter. In trailing 12 months, it's portfolio return was 5.87%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
eloxx pharmaceuticals inc5,512,580
indivior pharmaceuticals inc4,103,000
spruce biosciences inc1,554,930
moonlake immunotherapeutics973,500
azitra inc886,903
ultragenyx pharmaceutical in834,750
nuvectis pharma inc735,600
oruka therapeutics inc713,775
New stocks bought by Stonepine Capital Management, LLC

Additions

Ticker% Inc.
cabaletta bio inc1,734
edesa biotech inc1,421
satellos bioscience inc391
quoin pharmaceuticals ltd273
xilio therapeutics inc252
pasithea therapeutics corp164
arvinas inc118
phathom pharmaceuticals inc69.99
Additions to existing portfolio by Stonepine Capital Management, LLC

Reductions

Ticker% Reduced
boundless bio inc-74.13
codexis inc-73.76
compugen ltd-69.91
heron therapeutics inc-65.00
bioage labs inc-60.00
inhibikase therapeutics inc-58.61
precision optics corp inc ma-53.61
crescent biopharma inc.-52.94
Stonepine Capital Management, LLC reduced stake in above stock

Sold off

Ticker$ Sold
omniab inc-257,551
candel therapeutics inc-502,250
verrica pharmaceuticals inc-527,598
xoma royalty corporation-2,180,220
eledon pharmaceuticals inc-107,800
surrozen inc-961,436
janux therapeutics inc-278,000
bioatla inc-10,527
Stonepine Capital Management, LLC got rid off the above stocks

Sector Distribution

Stonepine Capital Management, LLC has about 70.1% of it's holdings in Healthcare sector.

  • Healthcare
  • Others
Sector%
Healthcare70.1
Others29.9

Market Cap. Distribution

Stonepine Capital Management, LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.

  • SMALL-CAP
  • UNALLOCATED
  • MICRO-CAP
  • MID-CAP
  • NANO-CAP
Category%
SMALL-CAP34.7
UNALLOCATED29.9
MICRO-CAP14.5
MID-CAP11.8
NANO-CAP9.1

Stocks belong to which Index?

About 24.3% of the stocks held by Stonepine Capital Management, LLC either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • RUSSELL 2000
Index%
Others75.7
RUSSELL 200024.3
Top 5 Winners (%)%
KZIA
kazia therapeutics ltd
89.3 %
ZNTL
zentalis pharmaceuticals inc
85.8 %
CNSP
cns pharmaceuticals inc
84.1 %
boundless bio inc
80.1 %
MXCT
maxcyte inc
65.6 %
Top 5 Winners ($)$
EOLS
evolus inc
4.7 M
KZIA
kazia therapeutics ltd
2.3 M
zevra therapeutics inc
1.9 M
ABEO
abeona therapeutics inc
1.1 M
ANTX
an2 therapeutics inc
0.9 M
Top 5 Losers (%)%
HRTX
heron therapeutics inc
-31.5 %
VSTM
verastem inc
-27.8 %
kalaris therapeutics inc
-25.9 %
PCSA
processa pharmaceuticals inc
-24.0 %
KTTA
pasithea therapeutics corp
-23.2 %
Top 5 Losers ($)$
VSTM
verastem inc
-4.9 M
TENX
tenax therapeutics inc
-1.2 M
AYTU
aytu biopharma inc
-0.5 M
ADMA
adma biologics inc
-0.5 M
HRTX
heron therapeutics inc
-0.4 M

Stonepine Capital Management, LLC Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Stonepine Capital Management, LLC

Stonepine Capital Management, LLC has 72 stocks in it's portfolio. About 40.9% of the portfolio is in top 10 stocks. VSTM proved to be the most loss making stock for the portfolio. EOLS was the most profitable stock for Stonepine Capital Management, LLC last quarter.

$131.36MTotal Value
80.00Positions
17 Aug, 2026Last Reported
Current holdings of Current Stock Holdings of Stonepine Capital Management, LLC, last reported on 17 Aug, 2026. Select a row with a linked ticker to view its historical trend.
ExpandHoldingsorted ascending% PortfolioShares Held$ Value% Change
CGEN
Compugen Ltd

Compugen Ltd

CGEN
Stonepine Capital Management, LLC's holding in Compugen Ltd over time
0.04%31,387
$67.2K
0.04%
decreased 69.91 percentreduced
CYBN
Cybin Inc

Cybin Inc

CYBN
Stonepine Capital Management, LLC's holding in Cybin Inc over time
0.48%129,280
$854.5K
0.48%
decreased 3.57 percentreduced