Latest Opaleye Management Inc. Stock Portfolio
$376Million
Equity Portfolio Value
Last Reported on: 14 Feb, 2024
About Opaleye Management Inc. and it’s 13F Hedge Fund Stock Holdings
Opaleye Management Inc. is a hedge fund based in Boston, MA. On 27-Mar-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $422 Millions. In it's latest 13F Holdings report, Opaleye Management Inc. reported an equity portfolio of $307.4 Millions as of 30 Sep, 2023.
The top stock holdings of Opaleye Management Inc. are HROW, , OCUL. The fund has invested 17.7% of it's portfolio in HARROW HEALTH INC and 13.7% of portfolio in ACELYRIN INC.
The fund managers got completely rid off CYMABAY THERAPEUTICS INC (CBAY), THERAVANCE BIOPHARMA INC (TBPH) and THESEUS PHARMACEUTICALS INC (THRX) stocks. They significantly reduced their stock positions in CRINETICS PHARMACEUTICALS INC (CRNX), TELA BIO INC (TELA) and VAXCYTE INC (PCVX). Opaleye Management Inc. opened new stock positions in TG THERAPEUTICS INC (TGTX), CATALYST PHARMACEUTICALS INC (CPRX) and BIODESIX (BDSX). The fund showed a lot of confidence in some stocks as they added substantially to KEZAR LIFE SCIENCES INC (KZR), IGM BIOSCIIENCES INC (IGMS) and VERASTEM INC (VSTM).
The top stock holdings of Opaleye Management Inc. are HROW, , OCUL. The fund has invested 17.7% of it's portfolio in HARROW HEALTH INC and 13.7% of portfolio in ACELYRIN INC.
The fund managers got completely rid off CYMABAY THERAPEUTICS INC (CBAY), THERAVANCE BIOPHARMA INC (TBPH) and THESEUS PHARMACEUTICALS INC (THRX) stocks. They significantly reduced their stock positions in CRINETICS PHARMACEUTICALS INC (CRNX), TELA BIO INC (TELA) and VAXCYTE INC (PCVX). Opaleye Management Inc. opened new stock positions in TG THERAPEUTICS INC (TGTX), CATALYST PHARMACEUTICALS INC (CPRX) and BIODESIX (BDSX). The fund showed a lot of confidence in some stocks as they added substantially to KEZAR LIFE SCIENCES INC (KZR), IGM BIOSCIIENCES INC (IGMS) and VERASTEM INC (VSTM).
New Buys
| Ticker | $ Bought |
|---|---|
| ARVINAS INC | 10,853,900 |
| ARCUTIS BIOTHERAPEUTICS INC | 6,330,800 |
| JASPER THERAPEUTICS INC | 3,144,430 |
| INTELLIA THERAPEUTICS INC | 3,018,510 |
| NEWAMSTERDAM PHARMA COMPANY | 2,964,380 |
| VENTYX BIOSCIENCES INC | 2,815,800 |
| SYROS PHARMACEUTICALS INC | 2,799,490 |
| PROTAGONIST THERAPEUTICS INC | 2,584,210 |
New stocks bought by Opaleye Management Inc.
Additions
| Ticker | % Inc. |
|---|---|
| RELMADA THERAPEUTICS INC | 2,823 |
| CODEXIS INC | 172 |
| TREVI THERAPEUTICS INC | 48.6 |
| IOVANCE BIOTHERAPEUTICS INC | 47.05 |
| APPLIED THERAPEUTICS | 22.34 |
| TG THERAPEUTICS INC | 17.2 |
| PRECIGEN INC | 9.05 |
| BRIDGEBIO PHARMA INC | 8.98 |
Additions to existing portfolio by Opaleye Management Inc.
Reductions
| Ticker | % Reduced |
|---|---|
| MORPHOSYS AG | -88.01 |
| KALVISTA PHARMACEUTICALS INC | -70.00 |
| BIOHAVEN LTD | -54.44 |
| GOSSAMER BIO INC | -37.27 |
| LARIMAR THERAPEUTICS INC | -26.52 |
| LIQUIDIA CORPORATION | -22.03 |
| NYXOAH S A | -21.97 |
| EDGEWISE THERAPEUTICS INC | -20.15 |
Opaleye Management Inc. reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| TRACON PHARMACEUTICALS INC | -848,082 |
| GERON CORP | -4,059,800 |
| TELA BIO INC | -6,000,000 |
| KEZAR LIFE SCIENCES INC | -505,750 |
| XERIS BIOPHARMA HOLDINGS INC | -725,400 |
| IGM BIOSCIIENCES INC | -2,179,350 |
| FORTRESS BIOTECH INC | -580,600 |
Opaleye Management Inc. got rid off the above stocks
Current Stock Holdings of Opaleye Management Inc.
Last Reported on: 14 Feb, 2024| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options |
|---|---|---|---|---|---|---|---|
| ALGS | ALIGOS THERAPEUTICS INC | 0.23 | 1,297,000 | 861,208 | NEW | ||
| APLT | APPLIED THERAPEUTICS | 0.97 | 1,092,500 | 3,659,880 | ADDED | 22.34 | |
| ARQT | ARCUTIS BIOTHERAPEUTICS INC | 1.68 | 1,960,000 | 6,330,800 | NEW | ||
| ARVN | ARVINAS INC | 2.89 | 263,700 | 10,853,900 | NEW | ||
| BDSX | BRIDGEBIO PHARMA INC | 0.96 | 496,500 | 3,610,660 | ADDED | 8.98 | |
| CDXS | CODEXIS INC | 2.47 | 3,045,520 | 9,288,850 | ADDED | 172 | |
| CNTX | CONTEXT THERAPEUTICS INC | 0.29 | 975,000 | 1,101,750 | NEW | ||
| CPRX | CATALYST PHARMACEUTICALS INC | 5.70 | 1,257,200 | 21,436,100 | ADDED | 4.33 | |
| CRNX | CRINETICS PHARMACEUTICALS INC | 2.91 | 307,500 | 10,940,800 | REDUCED | -16.89 | |
| ETON | ETON PHARMACEUTICALS INC | 2.95 | 2,529,890 | 11,080,900 | ADDED | 4.1 | |
| EWTX | EDGEWISE THERAPEUTICS INC | 2.03 | 699,000 | 7,647,060 | REDUCED | -20.15 | |
| FBIO | FORTRESS BIOTECH INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| FDMT | 4D MOLECULAR THERAPEUTICS INC | 1.66 | 308,500 | 6,250,210 | UNCHANGED | 0.00 | |
| FULC | FULCRUM THERAPEUTICS INC | 0.23 | 130,000 | 877,500 | NEW | ||
| GERN | GERON CORP | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| GOSS | GOSSAMER BIO INC | 0.78 | 8,000,000 | 2,915,110 | UNCHANGED | 0.00 | |
| GOSS | GOSSAMER BIO INC | 0.72 | 2,982,200 | 2,721,260 | REDUCED | -37.27 | |
| HROW | HARROW HEALTH INC | 11.38 | 3,820,000 | 42,784,000 | ADDED | 0.66 | |
| IDYA | IDEAYA BIOSCIENCES INC | 2.95 | 311,500 | 11,083,200 | UNCHANGED | 0.00 | |
| IGMS | IGM BIOSCIIENCES INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 1.94 | 897,000 | 7,292,610 | ADDED | 47.05 | |
| JSPR | JASPER THERAPEUTICS INC | 0.84 | 3,985,340 | 3,144,430 | NEW | ||
| KALV | KALVISTA PHARMACEUTICALS INC | 0.49 | 150,000 | 1,837,500 | REDUCED | -70.00 | |
| KNSA | KINIKSA PHARMACEUTICALS LTD | 0.17 | 37,500 | 640,210 | NEW | ||
| KROS | KEROS THERAPEUTICS INC | 3.78 | 357,500 | 14,214,200 | REDUCED | -0.8 | |
| KZR | KEZAR LIFE SCIENCES INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| LQDA | LIQUIDIA CORPORATION | 1.42 | 445,000 | 5,353,350 | REDUCED | -22.03 | |
| LRMR | LARIMAR THERAPEUTICS INC | 0.75 | 623,500 | 2,836,920 | REDUCED | -26.52 | |
| MOR | MORPHOSYS AG | 0.38 | 145,000 | 1,435,500 | REDUCED | -88.01 | |
| MRNS | MARINUS PHARMACEUTICALS INC | 1.63 | 563,500 | 6,125,240 | REDUCED | -3.51 | |
| NAMS | NEWAMSTERDAM PHARMA COMPANY | 0.79 | 265,388 | 2,964,380 | NEW | ||
| NTLA | INTELLIA THERAPEUTICS INC | 0.80 | 99,000 | 3,018,510 | NEW | ||
| OCUL | OCULAR THERAPEUTIX INC | 7.20 | 6,070,000 | 27,072,200 | REDUCED | -6.15 | |
| PCVX | VAXCYTE INC | 1.50 | 90,000 | 5,652,000 | UNCHANGED | 0.00 | |
| PGEN | PRECIGEN INC | 0.36 | 1,012,500 | 1,356,750 | ADDED | 9.05 | |
| PTGX | PROTAGONIST THERAPEUTICS INC | 0.69 | 112,700 | 2,584,210 | NEW | ||
| RLMD | RELMADA THERAPEUTICS INC | 0.96 | 877,000 | 3,630,780 | ADDED | 2,823 | |
| RYTM | RHYTHM PHARMACEUTICALS INC | 7.46 | 610,000 | 28,041,700 | REDUCED | -6.58 | |
| STRO | SUTRO BIOPHARMA INC | 0.34 | 301,491 | 1,293,400 | NEW | ||
| SYRS | SYROS PHARMACEUTICALS INC | 0.74 | 359,370 | 2,799,490 | NEW | ||
| TARA | PROTARA THERAPEUTICS INC | 1.34 | 2,692,590 | 5,048,880 | UNCHANGED | 0.00 | |
| TCON | TRACON PHARMACEUTICALS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| TELA | TELA BIO INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| TGTX | TG THERAPEUTICS INC | 10.06 | 2,215,000 | 37,832,200 | ADDED | 17.2 | |
| TRVI | TREVI THERAPEUTICS INC | 0.90 | 2,535,000 | 3,396,900 | ADDED | 48.6 | |
| URGN | UROGEN PHARMA LTD | 1.28 | 320,000 | 4,800,000 | UNCHANGED | 0.00 | |
| VSTM | VERASTEM INC | 0.46 | 211,400 | 1,720,800 | UNCHANGED | 0.00 | |
| VTYX | VENTYX BIOSCIENCES INC | 0.75 | 1,140,000 | 2,815,800 | NEW | ||
| XERS | XERIS BIOPHARMA HOLDINGS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| XOMA | XOMA CORP DEL | 1.23 | 250,000 | 4,625,000 | REDUCED | -8.93 | |
| ACELYRIN INC | 8.22 | 4,146,140 | 30,930,200 | UNCHANGED | 0.00 | ||
| BIOHAVEN LTD | 2.28 | 200,000 | 8,560,000 | REDUCED | -54.44 | ||
| NYXOAH S A | 0.42 | 344,800 | 1,599,870 | REDUCED | -21.97 |