Latest Opaleye Management Inc. Stock Portfolio
$437Million– No. of Holdings #49
Opaleye Management Inc. Performance:
2024 Q2: -9.77%YTD: 10.37%2023: 11.95%
Performance for 2024 Q2 is -9.77%, and YTD is 10.37%, and 2023 is 11.95%.
About Opaleye Management Inc. and 13F Hedge Fund Stock Holdings
Opaleye Management Inc. is a hedge fund based in BOSTON, MA. On 27-Mar-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $422 Millions. In it's latest 13F Holdings report, Opaleye Management Inc. reported an equity portfolio of $437.7 Millions as of 30 Jun, 2024.
The top stock holdings of Opaleye Management Inc. are HROW, TGTX, OCUL. The fund has invested 19% of it's portfolio in HARROW HEALTH INC and 9.3% of portfolio in TG THERAPEUTICS INC.
The fund managers got completely rid off CRINETICS PHARMACEUTICALS INC (CRNX), COMPASS THERAPEUTICS INC (CMPX) and NYXOAH S A stocks. They significantly reduced their stock positions in LYELL IMMUNOPHARMA INC (LYEL), IBIO INC (IBIO) and CATALYST PHARMACEUTICALS INC (CPRX). Opaleye Management Inc. opened new stock positions in IMMUNOME INC (IMNM), CYTOKINETICS INC (CYTK) and CARGO THERAPEUTICS INC. The fund showed a lot of confidence in some stocks as they added substantially to REGULUS THERAPEUTICS INC (RGLS), BIODESIX INC (BDSX) and VERASTEM INC (VSTM).
The top stock holdings of Opaleye Management Inc. are HROW, TGTX, OCUL. The fund has invested 19% of it's portfolio in HARROW HEALTH INC and 9.3% of portfolio in TG THERAPEUTICS INC.
The fund managers got completely rid off CRINETICS PHARMACEUTICALS INC (CRNX), COMPASS THERAPEUTICS INC (CMPX) and NYXOAH S A stocks. They significantly reduced their stock positions in LYELL IMMUNOPHARMA INC (LYEL), IBIO INC (IBIO) and CATALYST PHARMACEUTICALS INC (CPRX). Opaleye Management Inc. opened new stock positions in IMMUNOME INC (IMNM), CYTOKINETICS INC (CYTK) and CARGO THERAPEUTICS INC. The fund showed a lot of confidence in some stocks as they added substantially to REGULUS THERAPEUTICS INC (RGLS), BIODESIX INC (BDSX) and VERASTEM INC (VSTM).
Opaleye Management Inc. Equity Portfolio Value
Last Reported on: 14 Aug, 2024
Opaleye Management Inc. Annual Return Estimates Vs S&P 500
Our best estimate is that Opaleye Management Inc. made a return of -9.77% in the last quarter. In trailing 12 months, it's portfolio return was 23.96%.
New Buys
| Ticker | $ Bought |
|---|---|
| immunome inc | 13,340,200 |
| cytokinetics inc | 10,754,700 |
| cargo therapeutics inc | 9,124,590 |
| nuvalent inc | 4,498,500 |
| karyopharm therapeutics inc | 3,747,160 |
| lexicon pharmaceuticals inc | 3,150,000 |
| karyopharm therapeutics inc | 1,236,330 |
| aerovate therapeutics inc | 730,400 |
New stocks bought by Opaleye Management Inc.
Additions
| Ticker | % Inc. |
|---|---|
| regulus therapeutics inc | 766 |
| biodesix inc | 651 |
| verastem inc | 332 |
| fulcrum therapeutics inc | 119 |
| design therapeutics inc | 81.35 |
| arvinas inc | 68.18 |
| gossamer bio inc | 60.24 |
| nurix therapeutics inc | 56.78 |
Additions to existing portfolio by Opaleye Management Inc.
Reductions
| Ticker | % Reduced |
|---|---|
| lyell immunopharma inc | -50.22 |
| ibio inc | -44.85 |
| catalyst pharmaceuticals inc | -36.28 |
| aligos therapeutics inc | -22.7 |
| relmada therapeutics inc | -20.95 |
| ocular therapeutix inc | -20.23 |
| liquidia corporation | -17.72 |
| savara inc | -16.38 |
Opaleye Management Inc. reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| compass therapeutics inc | -6,276,600 |
| context therapeutics inc | -1,529,530 |
| precigen inc | -1,373,880 |
| revance therapeutics inc | -3,862,200 |
| nyxoah s a | -4,316,800 |
| crinetics pharmaceuticals inc | -9,830,100 |
| zentalis pharmaceuticals inc | -3,152,000 |
| larimar therapeutics inc | -1,323,800 |
Opaleye Management Inc. got rid off the above stocks
Sector Distribution
Opaleye Management Inc. has about 96.3% of it's holdings in Healthcare sector.
| Sector | % |
|---|---|
| Healthcare | 96.3 |
| Others | 3.7 |
Market Cap. Distribution
Opaleye Management Inc. has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.
| Category | % |
|---|---|
| SMALL-CAP | 53.6 |
| MID-CAP | 23 |
| MICRO-CAP | 16.5 |
| UNALLOCATED | 5.2 |
| NANO-CAP | 1.7 |
Stocks belong to which Index?
About 79% of the stocks held by Opaleye Management Inc. either belong to S&P 500 or RUSSELL 2000 index.
| Index | % |
|---|---|
| RUSSELL 2000 | 79 |
| Others | 21 |
Opaleye Management Inc. Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Opaleye Management Inc.
Opaleye Management Inc. has 49 stocks in it's portfolio. About 59% of the portfolio is in top 10 stocks. OCUL proved to be the most loss making stock for the portfolio. HROW was the most profitable stock for Opaleye Management Inc. last quarter.
Last Reported on: 14 Aug, 2024| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ABCL | abcellera biologics inc | 0.14 | 200,000 | 592,000 | new | |||
| ALGS | aligos therapeutics inc | 0.10 | 1,260,000 | 441,000 | reduced | -22.7 | ||
| ALLK | allakos inc | 0.64 | 2,780,000 | 2,780,000 | added | 14.17 | ||
| APLT | applied therapeutics inc' | 1.79 | 1,680,000 | 7,845,600 | reduced | -5.08 | ||
| ARVN | arvinas inc | 3.38 | 555,000 | 14,774,100 | added | 68.18 | ||
| AVTE | aerovate therapeutics inc | 0.17 | 440,000 | 730,400 | new | |||
| BDSX | biodesix inc | 1.41 | 4,020,000 | 6,150,600 | added | 651 | ||
| CDXS | codexis inc | 2.45 | 3,455,000 | 10,710,500 | added | 10.74 | ||
| CMPX | compass therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| CNTX | context therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| CPRX | catalyst pharmaceuticals inc | 2.27 | 640,000 | 9,913,600 | reduced | -36.28 | ||
| CRNX | crinetics pharmaceuticals inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| CYTK | cytokinetics inc | 2.46 | 198,500 | 10,754,700 | new | |||
| DSGN | design therapeutics inc | 0.16 | 205,000 | 686,750 | added | 81.35 | ||
| ETON | eton pharmaceuticals inc | 1.80 | 2,395,000 | 7,879,550 | reduced | -2.08 | ||
| EWTX | edgewise therapeutics inc | 2.39 | 580,000 | 10,445,800 | reduced | -12.78 | ||
| FDMT | 4d molecular therapeutics inc | 1.66 | 345,750 | 7,257,290 | added | 0.47 | ||
| FULC | fulcrum therapeutics inc | 0.40 | 285,000 | 1,767,000 | added | 119 | ||
| GKOS | glaukos corp | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| GOSS | gossamer bio inc | 0.90 | 8,000,000 | 3,957,750 | unchanged | 0.00 | ||