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Latest Opaleye Management Inc. Stock Portfolio

$458Million– No. of Holdings #51

Opaleye Management Inc. Performance:
2024 Q1: 22.32%YTD: 22.32%2023: 13.21%

Performance for 2024 Q1 is 22.32%, and YTD is 22.32%, and 2023 is 13.21%.

About Opaleye Management Inc. and 13F Hedge Fund Stock Holdings

Opaleye Management Inc. is a hedge fund based in BOSTON, MA. On 27-Mar-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $422 Millions. In it's latest 13F Holdings report, Opaleye Management Inc. reported an equity portfolio of $458.9 Millions as of 31 Mar, 2024.

The top stock holdings of Opaleye Management Inc. are OCUL, HROW, TGTX. The fund has invested 13.2% of it's portfolio in OCULAR THERAPEUTIX INC and 11.3% of portfolio in HARROW HEALTH INC.

The fund managers got completely rid off IDEAYA BIOSCIENCES INC (IDYA), BIOHAVEN LTD and ARCUTIS BIOTHERAPEUTICS INC (ARQT) stocks. They significantly reduced their stock positions in LARIMAR THERAPEUTICS INC (LRMR), ACELYRIN INC and MORPHOSYS AG (MOR). Opaleye Management Inc. opened new stock positions in JASPER THERAPEUTICS INC (JSPR), LYELL IMMUNOPHARMA INC (LYEL) and COMPASS THERAPEUTICS INC (CMPX). The fund showed a lot of confidence in some stocks as they added substantially to INTELLIA THERAPEUTICS INC (NTLA), SYROS PHARMACEUTICALS INC (SYRS) and APPLIED THERAPEUTICS (APLT).
Opaleye Management Inc. Equity Portfolio Value
Last Reported on: 29 May, 2024

Opaleye Management Inc. Annual Return Estimates Vs S&P 500

Our best estimate is that Opaleye Management Inc. made a return of 22.32% in the last quarter. In trailing 12 months, it's portfolio return was 28.66%.

New Buys

Ticker$ Bought
jasper therapeutics inc12,788,400
lyell immunopharma inc7,481,650
compass therapeutics inc6,276,600
savara inc4,257,900
nurix therapeutics inc3,927,990
revance therapeutics inc3,862,200
zentalis pharmaceuticals inc3,152,000
allakos inc3,068,100

New stocks bought by Opaleye Management Inc.

Additions

Ticker% Inc.
intellia therapeutics inc157
syros pharmaceuticals inc119
applied therapeutics62.01
aligos therapeutics inc25.67
arvinas inc25.14
newamsterdam pharma company18.84
context therapeutics inc13.68
ventyx biosciences inc12.72

Additions to existing portfolio by Opaleye Management Inc.

Reductions

Ticker% Reduced
larimar therapeutics inc-72.03
acelyrin inc-61.89
morphosys ag-55.17
crinetics pharmaceuticals inc-31.71
catalyst pharmaceuticals inc-20.11
gossamer bio inc-18.18
urogen pharma ltd-15.62
rhythm pharmaceuticals inc-15.57

Opaleye Management Inc. reduced stake in above stock

Opaleye Management Inc. got rid off the above stocks

Sector Distribution

Opaleye Management Inc. has about 94.8% of it's holdings in Healthcare sector.

Sector%
Healthcare94.8
Others5.2

Market Cap. Distribution

Opaleye Management Inc. has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.

Category%
SMALL-CAP53.5
MID-CAP23.6
MICRO-CAP16.8
UNALLOCATED5.2

Stocks belong to which Index?

About 80.2% of the stocks held by Opaleye Management Inc. either belong to S&P 500 or RUSSELL 2000 index.

Index%
RUSSELL 200080.2
Others19.8
Top 5 Winners (%)%
IBIO
ibio inc
244.1 %
TRVI
trevi therapeutics inc
148.6 %
VTYX
ventyx biosciences inc
122.7 %
TARA
protara therapeutics inc
113.9 %
RGLS
regulus therapeutics inc
97.3 %
Top 5 Winners ($)$
OCUL
ocular therapeutix inc
29.1 M
KROS
keros therapeutics inc
9.5 M
HROW
harrow health inc
8.0 M
IOVA
iovance biotherapeutics inc
6.0 M
TARA
protara therapeutics inc
5.7 M
Top 5 Losers (%)%
BDSX
biodesix
-79.2 %
RPTX
repare therapeutics inc
-28.0 %
SYRS
syros pharmaceuticals inc
-27.7 %
ETON
eton pharmaceuticals inc
-13.9 %
RVNC
revance therapeutics inc
-13.1 %
Top 5 Losers ($)$
TGTX
tg therapeutics inc
-4.2 M
BDSX
biodesix
-2.9 M
CPRX
catalyst pharmaceuticals inc
-1.7 M
SYRS
syros pharmaceuticals inc
-1.6 M
RYTM
rhythm pharmaceuticals inc
-1.6 M

Opaleye Management Inc. Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Opaleye Management Inc.

Opaleye Management Inc. has 51 stocks in it's portfolio. About 57% of the portfolio is in top 10 stocks. TGTX proved to be the most loss making stock for the portfolio. OCUL was the most profitable stock for Opaleye Management Inc. last quarter.

Last Reported on: 29 May, 2024
TickerNamesorted ascending% PortfolioShares Held$ ValueType% ChangeOptions