Latest VR Adviser, LLC Stock Portfolio

$2.68Billion– No. of Holdings #33

VR Adviser, LLC Performance:
2026 Q1: 22.02%YTD: 22.02%2025: 58.45%

Performance for 2026 Q1 is 22.02%, and YTD is 22.02%, and 2025 is 58.45%.

About VR Adviser, LLC and 13F Hedge Fund Stock Holdings

VR ADVISER, LLC is a hedge fund based in New York, NY. On 2026-05-15, the fund reported it's updated stock portfolio. In the 13F Holdings report, VR ADVISER, LLC reported an equity portfolio of $2.7 Billions as of 31 Mar, 2026.

The top stock holdings of VR ADVISER, LLC are , ERAS, . The fund has invested 26.7% of it's portfolio in APOGEE THERAPEUTICS INC and 9.9% of portfolio in ERASCA INC.

The fund managers got completely rid off UPSTREAM BIO INC stocks. They significantly reduced their stock positions in ENLIVEN THERAPEUTICS INC, CYTOMX THERAPEUTICS INC (CTMX) and ORIC PHARMACEUTICALS INC (ORIC). VR ADVISER, LLC opened new stock positions in DAMORA THERAPEUTICS INC (GLTO), RELMADA THERAPEUTICS INC (RLMD) and TENAX THERAPEUTICS INC (TENX). The fund showed a lot of confidence in some stocks as they added substantially to VOR BIOPHARMA INC (VOR), OCULAR THERAPEUTIX INC (OCUL) and ZURA BIO LTD.
VR Adviser, LLC Equity Portfolio Value
Last Reported on: 15 May, 2026

VR Adviser, LLC Annual Return Estimates Vs S&P 500

Our best estimate is that Venrock Adviser, LLC made a return of 22.02% in the last quarter. In trailing 12 months, it's portfolio return was 150.99%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
damora therapeutics inc93,333,100
relmada therapeutics inc33,709,900
tenax therapeutics inc26,787,400
adlai nortye ltd22,232,100
century therapeutics inc19,652,200
korro bio inc11,427,500
alto neuroscience inc11,240,000
x4 pharmaceuticals inc1,365,070

New stocks bought by VR Adviser, LLC

Additions

Ticker% Inc.
vor biopharma inc56.49
ocular therapeutix inc41.44
zura bio ltd20.39
dianthus therapeutics inc18.00
maze therapeutics inc3.45
cybin inc0.3

Additions to existing portfolio by VR Adviser, LLC

Reductions

Ticker% Reduced
enliven therapeutics inc-46.49
cytomx therapeutics inc-35.85
oric pharmaceuticals inc-23.9
septerna inc-17.15
erasca inc-8.26
kalvista pharmaceuticals inc-3.78

VR Adviser, LLC reduced stake in above stock

Sold off

Ticker$ Sold
upstream bio inc-31,746,400
casi pharmaceuticals inc-839,170

VR Adviser, LLC got rid off the above stocks

Sector Distribution

Venrock Adviser, LLC has about 50.4% of it's holdings in Healthcare sector.

  • Healthcare
  • Others
Sector%
Healthcare50.4
Others49.6

Market Cap. Distribution

Venrock Adviser, LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.

  • UNALLOCATED
  • MID-CAP
  • SMALL-CAP
  • MICRO-CAP
  • NANO-CAP
Category%
UNALLOCATED49.6
MID-CAP24
SMALL-CAP17.2
MICRO-CAP5.8
NANO-CAP3.5

Stocks belong to which Index?

About 35.3% of the stocks held by Venrock Adviser, LLC either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • RUSSELL 2000
Index%
Others64.7
RUSSELL 200035.3
Top 5 Winners (%)%
ERAS
erasca inc
321.1 %
enliven therapeutics inc
118.6 %
dianthus therapeutics inc
88.7 %
oruka therapeutics inc
61.8 %
crescent biopharma inc.
54.9 %
Top 5 Winners ($)$
ERAS
erasca inc
213.3 M
oruka therapeutics inc
77.7 M
apogee therapeutics inc
73.8 M
AGLE
spyre therapeutics inc
65.2 M
enliven therapeutics inc
58.9 M
Top 5 Losers (%)%
CYBN
cybin inc
-41.3 %
VRDN
viridian therapeutics inc
-37.1 %
maze therapeutics inc
-27.6 %
OCUL
ocular therapeutix inc
-27.0 %
engene holdings inc
-24.6 %
Top 5 Losers ($)$
VRDN
viridian therapeutics inc
-44.9 M
OCUL
ocular therapeutix inc
-32.4 M
maze therapeutics inc
-18.2 M
CYBN
cybin inc
-13.0 M
engene holdings inc
-10.6 M

VR Adviser, LLC Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of VR Adviser, LLC

Venrock Adviser, LLC has 33 stocks in it's portfolio. About 72.1% of the portfolio is in top 10 stocks. VRDN proved to be the most loss making stock for the portfolio. ERAS was the most profitable stock for Venrock Adviser, LLC last quarter.

Last Reported on: 15 May, 2026
TickerNamesorted ascending% PortfolioShares Held$ ValueType% ChangeOptions