Latest VR Adviser, LLC Stock Portfolio

$3.30Billion | No. of Holdings #33

VR Adviser, LLC Performance

2026 Q2+34.04%
YTD+63.56%
2025+58.45%

About VR Adviser, LLC and 13F Hedge Fund Stock Holdings

Venrock Adviser, LLC is a hedge fund based in New York, NY. On 2026-08-14, the fund reported it's updated stock portfolio. In the 13F Holdings report, Venrock Adviser, LLC reported an equity portfolio of $3.3 Billions as of 30 Jun, 2026. <br><br> The top stock holdings of Venrock Adviser, LLC are , , ERAS. The fund has invested 34.2% of it's portfolio in APOGEE THERAPEUTICS INC and 12% of portfolio in ORUKA THERAPEUTICS INC. <br><br> The fund managers got completely rid off KALVISTA PHARMACEUTICALS INC (KALV), ENGENE HOLDINGS INC and TENAX THERAPEUTICS INC (TENX) stocks. They significantly reduced their stock positions in ENLIVEN THERAPEUTICS INC, CYTOMX THERAPEUTICS INC (CTMX) and SPYRE THERAPEUTICS INC (AGLE). Venrock Adviser, LLC opened new stock positions in ACHIEVE LIFE SCIENCE INC (ACHV), PARABILIS MEDICINES INC and INMED PHARMACEUTICALS INC (INM). The fund showed a lot of confidence in some stocks as they added substantially to X4 PHARMACEUTICALS INC (XFOR), RELMADA THERAPEUTICS INC (RLMD) and ARTIVA BIOTHERAPEUTICS INC.
VR Adviser, LLC Equity Portfolio Value
Last Reported on: 14 Aug, 2026
$3.30Billion
  as of Aug 14, 2026

VR Adviser, LLC Annual Return Estimates Vs S&P 500

Our best estimate is that Venrock Adviser, LLC made a return of 34.04% in the last quarter. In trailing 12 months, it's portfolio return was 203.25%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
achieve life science inc17,964,200
parabilis medicines inc17,106,200
research alliance corp iii3,210,000
inmed pharmaceuticals inc50,662

New stocks bought by VR Adviser, LLC

Additions

Ticker% Inc.
x4 pharmaceuticals inc485
relmada therapeutics inc41.31
artiva biotherapeutics inc26.97
erasca inc9.21
savara inc7.32

Additions to existing portfolio by VR Adviser, LLC

Reductions

Ticker% Reduced
enliven therapeutics inc-69.51
cytomx therapeutics inc-50.09
spyre therapeutics inc-18.99
cogent biosciences inc-17.89
viridian therapeutics inc-16.09

VR Adviser, LLC reduced stake in above stock

Sold off

Ticker$ Sold
kalvista pharmaceuticals inc-130,331,000
engene holdings inc-32,493,300
tenax therapeutics inc-26,787,400
septerna inc-12,160,500

VR Adviser, LLC got rid off the above stocks

Sector Distribution

Venrock Adviser, LLC has about 58.1% of it's holdings in Others sector.

  • Others
  • Healthcare
Sector%
Others58.1
Healthcare41.9

Market Cap. Distribution

Venrock Adviser, LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.

  • UNALLOCATED
  • MID-CAP
  • SMALL-CAP
Category%
UNALLOCATED58.1
MID-CAP23.2
SMALL-CAP18.2

Stocks belong to which Index?

About 27.9% of the stocks held by Venrock Adviser, LLC either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • RUSSELL 2000
Index%
Others72.1
RUSSELL 200027.9
Top 5 Winners (%)%
oruka therapeutics inc
94.0 %
AGLE
spyre therapeutics inc
68.8 %
adlai nortye ltd
66.2 %
AVTE
jade biosciences inc
58.1 %
apogee therapeutics inc
57.7 %
Top 5 Winners ($)$
apogee therapeutics inc
412.4 M
oruka therapeutics inc
191.3 M
AGLE
spyre therapeutics inc
127.9 M
ERAS
erasca inc
36.7 M
AVTE
jade biosciences inc
26.3 M
Top 5 Losers (%)%
CTMX
cytomx therapeutics inc
-15.2 %
ORIC
oric pharmaceuticals inc
-14.5 %
SRZN
surrozen inc
-10.9 %
VRDN
viridian therapeutics inc
-5.6 %
crescent biopharma inc.
-2.0 %
Top 5 Losers ($)$
ORIC
oric pharmaceuticals inc
-7.9 M
CTMX
cytomx therapeutics inc
-7.1 M
VRDN
viridian therapeutics inc
-4.2 M
SRZN
surrozen inc
-2.0 M
crescent biopharma inc.
-0.8 M

VR Adviser, LLC Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of VR Adviser, LLC

Venrock Adviser, LLC has 33 stocks in it's portfolio. About 80.4% of the portfolio is in top 10 stocks. ORIC proved to be the most loss making stock for the portfolio. was the most profitable stock for Venrock Adviser, LLC last quarter.

$3.30BTotal Value
37.00Positions
14 Aug, 2026Last Reported
Current holdings of Current Stock Holdings of VR Adviser, LLC, last reported on 14 Aug, 2026. Select a row with a linked ticker to view its historical trend.
ExpandHoldingsorted ascending% PortfolioShares Held$ Value% Change
CYBN
Cybin Inc

Cybin Inc

CYBN
VR Adviser, LLC's holding in Cybin Inc over time
0.77%3,851,650
$25.46M
0.77%
unchanged 0 percentunchanged