Latest New Leaf Venture Partners, L.L.C. Stock Portfolio
New Leaf Venture Partners, L.L.C. Performance:
2025 Q3: -12.19%YTD: -36.42%2024: -14.1%
Performance for 2025 Q3 is -12.19%, and YTD is -36.42%, and 2024 is -14.1%.
About New Leaf Venture Partners, L.L.C. and 13F Hedge Fund Stock Holdings
New Leaf Venture Partners, L.L.C. is a hedge fund based in NEW YORK, NY. On 31-Mar-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $605.5 Millions. In it's latest 13F Holdings report, New Leaf Venture Partners, L.L.C. reported an equity portfolio of $43 Millions as of 30 Sep, 2025.
The top stock holdings of New Leaf Venture Partners, L.L.C. are EWTX, ARVN, CRNX. The fund has invested 38.8% of it's portfolio in EWTX and 31.4% of portfolio in ARVN.
The fund managers got completely rid off ITERUM THERAPEUTICS PLC (ITRM) stocks. They significantly reduced their stock positions in PASG (PASG).
The top stock holdings of New Leaf Venture Partners, L.L.C. are EWTX, ARVN, CRNX. The fund has invested 38.8% of it's portfolio in EWTX and 31.4% of portfolio in ARVN.
The fund managers got completely rid off ITERUM THERAPEUTICS PLC (ITRM) stocks. They significantly reduced their stock positions in PASG (PASG).
New Leaf Venture Partners, L.L.C. Annual Return Estimates Vs S&P 500
Our best estimate is that New Leaf Venture Partners, L.L.C. made a return of -12.19% in the last quarter. In trailing 12 months, it's portfolio return was -43.77%.
New Buys
Additions
Reductions
| Ticker | % Reduced |
|---|---|
| pasg | -30.00 |
New Leaf Venture Partners, L.L.C. reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| iterum therapeutics plc | -343,295 |
New Leaf Venture Partners, L.L.C. got rid off the above stocks
Sector Distribution
New Leaf Venture Partners, L.L.C. has about 100% of it's holdings in Healthcare sector.
| Sector | % |
|---|---|
| Healthcare | 100 |
Market Cap. Distribution
New Leaf Venture Partners, L.L.C. has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.
| Category | % |
|---|---|
| SMALL-CAP | 80.9 |
| MID-CAP | 13.6 |
| MICRO-CAP | 5.5 |
Stocks belong to which Index?
About 98.4% of the stocks held by New Leaf Venture Partners, L.L.C. either belong to S&P 500 or RUSSELL 2000 index.
| Index | % |
|---|---|
| RUSSELL 2000 | 98.4 |
| Others | 1.6 |
New Leaf Venture Partners, L.L.C. Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of New Leaf Venture Partners, L.L.C.
New Leaf Venture Partners, L.L.C. has 7 stocks in it's portfolio. PASG proved to be the most loss making stock for the portfolio. EWTX was the most profitable stock for New Leaf Venture Partners, L.L.C. last quarter.
Last Reported on: 14 Nov, 2025| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ALEC | alec | 2.34 | 339,569 | 1,005,120 | unchanged | 0.00 | ||
| ARVN | arvn | 31.38 | 1,585,720 | 13,510,300 | unchanged | 0.00 | ||
| COGT | cogt | 8.37 | 250,765 | 3,600,980 | unchanged | 0.00 | ||
| CRNX | crnx | 13.64 | 141,000 | 5,872,650 | unchanged | 0.00 | ||
| EWTX | ewtx | 38.81 | 1,030,160 | 16,709,200 | unchanged | 0.00 | ||
| ITRM | iterum therapeutics plc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| PASG | pasg | 1.63 | 87,426 | 702,031 | reduced | -30.00 | ||
| RLYB | rlyb | 3.83 | 3,301,600 | 1,647,500 | unchanged | 0.00 | ||