Latest Avoro Capital Advisors LLC Stock Portfolio

$11.14Billion | No. of Holdings #26

Avoro Capital Advisors LLC Performance

2026 Q2+17.32%
YTD+22.04%
2025+47.90%

About Avoro Capital Advisors LLC and 13F Hedge Fund Stock Holdings

Avoro Capital Advisors LLC is a hedge fund based in New York, NY. On 2026-08-14, the fund reported it's updated stock portfolio. In the 13F Holdings report, Avoro Capital Advisors LLC reported an equity portfolio of $11.1 Billions as of 30 Jun, 2026. <br><br> The top stock holdings of Avoro Capital Advisors LLC are UTHR, , KRYS. The fund has invested 13.5% of it's portfolio in UNITED THERAPEUTICS CORP and 12.2% of portfolio in ASCENDIS PHARMA. <br><br> The fund managers got completely rid off ASCENDIS PHARMA (ASND), APELLIS PHARMACEUTICALS INC (APLS) and CENTESSA PHARMACEUTICALS PLC (CNTA) stocks. They significantly reduced their stock positions in LEXEO THERAPEUTICS INC, VERA THERAPEUTICS INC (VERA) and REVOLUTION MEDICINES INC (RVMD). Avoro Capital Advisors LLC opened new stock positions in ASCENDIS PHARMA and FAETH THERAPEUTICS INC (SNSE). The fund showed a lot of confidence in some stocks as they added substantially to VIRIDIAN THERAPEUTICS INC (VRDN), AVALO THERAPEUTICS (AVTX) and CYTOKINETICS INC (CYTK).
Avoro Capital Advisors LLC Equity Portfolio Value
Last Reported on: 14 Aug, 2026
$11.14Billion
  as of Aug 14, 2026

Avoro Capital Advisors LLC Annual Return Estimates Vs S&P 500

Our best estimate is that Avoro Capital Advisors LLC made a return of 17.32% in the last quarter. In trailing 12 months, it's portfolio return was 93.68%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
ascendis pharma1,363,240,000
hemab therapeutics hldgs inc70,710,800
faeth therapeutics inc36,101,000

New stocks bought by Avoro Capital Advisors LLC

Additions to existing portfolio by Avoro Capital Advisors LLC

Reductions

Ticker% Reduced
lexeo therapeutics inc-20.58
vera therapeutics inc-2.8
revolution medicines inc-2.02

Avoro Capital Advisors LLC reduced stake in above stock

Sold off

Ticker$ Sold
apellis pharmaceuticals inc-491,700,000
centessa pharmaceuticals plc-454,018,000
terns pharmaceuticals inc-300,240,000
ascendis pharma-1,157,950,000
soleno therapeutics inc-77,004,000
mannkind corp-5,390,000
alkermes plc-42,432,000

Avoro Capital Advisors LLC got rid off the above stocks

Sector Distribution

Avoro Capital Advisors LLC has about 71.7% of it's holdings in Healthcare sector.

  • Healthcare
  • Others
Sector%
Healthcare71.7
Others28.3

Market Cap. Distribution

Avoro Capital Advisors LLC has about 44.2% of it's portfolio invested in the large-cap and mega-cap stocks.

  • LARGE-CAP
  • UNALLOCATED
  • MID-CAP
  • SMALL-CAP
Category%
LARGE-CAP44.2
UNALLOCATED28.3
MID-CAP23.2
SMALL-CAP3.8

Stocks belong to which Index?

About 49.2% of the stocks held by Avoro Capital Advisors LLC either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • RUSSELL 2000
Index%
Others50.8
RUSSELL 200049.2
Top 5 Winners (%)%
QURE
uniqure nv
155.2 %
definium therapeutics inc
102.9 %
RVMD
revolution medicines inc
91.6 %
GHRS
gh research plc
91.2 %
TSHA
taysha gene therapies inc
48.8 %
Top 5 Winners ($)$
KRYS
krystal biotech inc
327.5 M
KYMR
kymera therapeutics inc
234.6 M
RVMD
revolution medicines inc
208.9 M
ARWR
arrowhead pharmaceuticals inc
207.4 M
ARGX
argenx se
197.5 M
Top 5 Losers (%)%
lexeo therapeutics inc
-17.0 %
UTHR
united therapeutics corp
-8.4 %
CELC
celcuity inc
-8.3 %
VRDN
viridian therapeutics inc
-4.9 %
Top 5 Losers ($)$
UTHR
united therapeutics corp
-138.3 M
CELC
celcuity inc
-32.2 M
VRDN
viridian therapeutics inc
-2.4 M
lexeo therapeutics inc
-1.8 M

Avoro Capital Advisors LLC Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Avoro Capital Advisors LLC

Avoro Capital Advisors LLC has 26 stocks in it's portfolio. About 79.5% of the portfolio is in top 10 stocks. UTHR proved to be the most loss making stock for the portfolio. KRYS was the most profitable stock for Avoro Capital Advisors LLC last quarter.

$11.14BTotal Value
33.00Positions
14 Aug, 2026Last Reported
Current holdings of Current Stock Holdings of Avoro Capital Advisors LLC, last reported on 14 Aug, 2026. Select a row with a linked ticker to view its historical trend.
ExpandHoldingsorted ascending% PortfolioShares Held$ Value% Change
ARGX
Argenx Se

Argenx Se

ARGX
Avoro Capital Advisors LLC's holding in Argenx Se over time
8.33%1,000,000
$927.77M
8.33%
unchanged 0 percentunchanged
ASND
Ascendis Pharma

Ascendis Pharma

ASND
Avoro Capital Advisors LLC's holding in Ascendis Pharma over time
0%0.00
$0.00
0%
decreased 100 percentsold off
GHRS
Gh Research Plc

Gh Research Plc

GHRS
Avoro Capital Advisors LLC's holding in Gh Research Plc over time
0.43%1,800,000
$48.38M
0.43%
unchanged 0 percentunchanged