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Latest Avoro Capital Advisors LLC Stock Portfolio

$10.16Billion | No. of Holdings #30

Avoro Capital Advisors LLC Performance

2026 Q1+4.02%
YTD+4.02%
2025+47.90%

About Avoro Capital Advisors LLC and 13F Hedge Fund Stock Holdings

Avoro Capital Advisors LLC is a hedge fund based in New York, NY. On 2026-05-15, the fund reported it's updated stock portfolio. In the 13F Holdings report, Avoro Capital Advisors LLC reported an equity portfolio of $10.2 Billions as of 31 Mar, 2026. <br><br> The top stock holdings of Avoro Capital Advisors LLC are UTHR, ASND, MDGL. The fund has invested 15.3% of it's portfolio in UNITED THERAPEUTICS CORP and 11.4% of portfolio in ASCENDIS PHARMA. <br><br> The fund managers got completely rid off AVIDITY BIOSCIENCES INC (RNA), SPDR SERIES TRUST - S&P BIOTECH (BIL) and MIND MEDICINE (MINDMED) INC (MNMD) stocks. They significantly reduced their stock positions in MANNKIND CORP (MNKD), LEXEO THERAPEUTICS INC and CENTESSA PHARMACEUTICALS PLC (CNTA). Avoro Capital Advisors LLC opened new stock positions in CYTOKINETICS INC (CYTK), DAMORA THERAPEUTICS INC (GLTO) and DEFINIUM THERAPEUTICS INC. The fund showed a lot of confidence in some stocks as they added substantially to TERNS PHARMACEUTICALS INC (TERN), OCULAR THERAPEUTIX INC (OCUL) and CELCUITY INC (CELC).
Avoro Capital Advisors LLC Equity Portfolio Value
Last Reported on: 15 May, 2026
$10.16Billion
  as of May 15, 2026

Avoro Capital Advisors LLC Annual Return Estimates Vs S&P 500

Our best estimate is that Avoro Capital Advisors LLC made a return of 4.02% in the last quarter. In trailing 12 months, it's portfolio return was 66.36%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
cytokinetics inc219,700,000
damora therapeutics inc97,979,700
definium therapeutics inc94,500,000
avalo therapeutics21,051,300
New stocks bought by Avoro Capital Advisors LLC

Additions

Ticker% Inc.
terns pharmaceuticals inc30.92
ocular therapeutix inc14.26
celcuity inc8.48
revolution medicines inc8.04
xenon pharmaceuticals inc6.51
argenx se1.01
united therapeutics corp0.92
arrowhead pharmaceuticals inc0.71
Additions to existing portfolio by Avoro Capital Advisors LLC

Reductions

Ticker% Reduced
mannkind corp-50.5
lexeo therapeutics inc-43.18
centessa pharmaceuticals plc-21.47
soleno therapeutics inc-20.69
alkermes plc-14.29
uniqure nv-3.1
ascendis pharma-0.95
Avoro Capital Advisors LLC reduced stake in above stock

Sold off

Ticker$ Sold
avidity biosciences inc-393,469,000
mind medicine (mindmed) inc-66,950,000
spdr series trust - s&p biotech-256,053,000
oruka therapeutics inc-40,413,500
ptc therapeutics inc-52,032,600
apogee therapeutics inc-37,740,000
incyte corp-13,334,000
Avoro Capital Advisors LLC got rid off the above stocks

Sector Distribution

Avoro Capital Advisors LLC has about 76.7% of it's holdings in Healthcare sector.

  • Healthcare
  • Others
Sector%
Healthcare76.7
Others23.3

Market Cap. Distribution

Avoro Capital Advisors LLC has about 27% of it's portfolio invested in the large-cap and mega-cap stocks.

  • MID-CAP
  • LARGE-CAP
  • UNALLOCATED
  • SMALL-CAP
Category%
MID-CAP45.4
LARGE-CAP27
UNALLOCATED23.3
SMALL-CAP3

Stocks belong to which Index?

About 44.8% of the stocks held by Avoro Capital Advisors LLC either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • RUSSELL 2000
Index%
Others55.2
RUSSELL 200044.8
Top 5 Winners (%)%
APLS
apellis pharmaceuticals inc
60.1 %
CNTA
centessa pharmaceuticals plc
52.5 %
AADI
whitehawk therapeutics inc
42.6 %
XENE
xenon pharmaceuticals inc
28.6 %
TERN
terns pharmaceuticals inc
26.0 %
Top 5 Winners ($)$
UTHR
united therapeutics corp
276.8 M
CNTA
centessa pharmaceuticals plc
191.1 M
APLS
apellis pharmaceuticals inc
184.7 M
ASND
ascendis pharma
78.8 M
XENE
xenon pharmaceuticals inc
74.7 M
Top 5 Losers (%)%
MNKD
mannkind corp
-42.5 %
VRDN
viridian therapeutics inc
-37.1 %
lexeo therapeutics inc
-33.1 %
QURE
uniqure nv
-31.2 %
structure therapeutics inc
-30.7 %
Top 5 Losers ($)$
structure therapeutics inc
-140.0 M
ARGX
argenx se
-110.1 M
MDGL
madrigal pharmaceuticals inc
-106.7 M
VERA
vera therapeutics inc
-61.3 M
QURE
uniqure nv
-45.9 M

Avoro Capital Advisors LLC Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Avoro Capital Advisors LLC

Avoro Capital Advisors LLC has 30 stocks in it's portfolio. About 76.4% of the portfolio is in top 10 stocks. proved to be the most loss making stock for the portfolio. UTHR was the most profitable stock for Avoro Capital Advisors LLC last quarter.

$10.15BTotal Value
37.00Positions
15 May, 2026Last Reported
Current holdings of Current Stock Holdings of Avoro Capital Advisors LLC, last reported on 15 May, 2026. Select a row with a linked ticker to view its historical trend.
ExpandHoldingsorted ascending% PortfolioShares Held$ Value% Change
ARGX
Argenx Se

Argenx Se

ARGX
Avoro Capital Advisors LLC's holding in Argenx Se over time
7.18%1,000,000
$730.25M
7.18%
increased 1.01 percentadded
ASND
Ascendis Pharma

Ascendis Pharma

ASND
Avoro Capital Advisors LLC's holding in Ascendis Pharma over time
11.39%5,062,500
$1.16B
11.39%
decreased 0.95 percentreduced
BIL
Spdr Series Trust - S&P Biotech

Spdr Series Trust - S&P Biotech

BIL
Avoro Capital Advisors LLC's holding in Spdr Series Trust - S&P Biotech over time
0%0.00
$0.00
0%
decreased 100 percentsold off
GHRS
Gh Research Plc

Gh Research Plc

GHRS
Avoro Capital Advisors LLC's holding in Gh Research Plc over time
0.25%1,800,000
$25.31M
0.25%
unchanged 0 percentunchanged