Latest Avoro Capital Advisors LLC Stock Portfolio
$10.16Billion– No. of Holdings #30
Avoro Capital Advisors LLC Performance:
2026 Q1: 4.02%YTD: 4.02%2025: 47.9%
Performance for 2026 Q1 is 4.02%, and YTD is 4.02%, and 2025 is 47.9%.
About Avoro Capital Advisors LLC and 13F Hedge Fund Stock Holdings
Avoro Capital Advisors LLC is a hedge fund based in New York, NY. On 2026-05-15, the fund reported it's updated stock portfolio. In the 13F Holdings report, Avoro Capital Advisors LLC reported an equity portfolio of $10.2 Billions as of 31 Mar, 2026.
The top stock holdings of Avoro Capital Advisors LLC are UTHR, ASND, MDGL. The fund has invested 15.3% of it's portfolio in UNITED THERAPEUTICS CORP and 11.4% of portfolio in ASCENDIS PHARMA.
The fund managers got completely rid off AVIDITY BIOSCIENCES INC (RNA), SPDR SERIES TRUST - S&P BIOTECH (BIL) and MIND MEDICINE (MINDMED) INC (MNMD) stocks. They significantly reduced their stock positions in MANNKIND CORP (MNKD), LEXEO THERAPEUTICS INC and CENTESSA PHARMACEUTICALS PLC (CNTA). Avoro Capital Advisors LLC opened new stock positions in CYTOKINETICS INC (CYTK), DAMORA THERAPEUTICS INC (GLTO) and DEFINIUM THERAPEUTICS INC. The fund showed a lot of confidence in some stocks as they added substantially to TERNS PHARMACEUTICALS INC (TERN), OCULAR THERAPEUTIX INC (OCUL) and CELCUITY INC (CELC).
The top stock holdings of Avoro Capital Advisors LLC are UTHR, ASND, MDGL. The fund has invested 15.3% of it's portfolio in UNITED THERAPEUTICS CORP and 11.4% of portfolio in ASCENDIS PHARMA.
The fund managers got completely rid off AVIDITY BIOSCIENCES INC (RNA), SPDR SERIES TRUST - S&P BIOTECH (BIL) and MIND MEDICINE (MINDMED) INC (MNMD) stocks. They significantly reduced their stock positions in MANNKIND CORP (MNKD), LEXEO THERAPEUTICS INC and CENTESSA PHARMACEUTICALS PLC (CNTA). Avoro Capital Advisors LLC opened new stock positions in CYTOKINETICS INC (CYTK), DAMORA THERAPEUTICS INC (GLTO) and DEFINIUM THERAPEUTICS INC. The fund showed a lot of confidence in some stocks as they added substantially to TERNS PHARMACEUTICALS INC (TERN), OCULAR THERAPEUTIX INC (OCUL) and CELCUITY INC (CELC).
Avoro Capital Advisors LLC Equity Portfolio Value
Last Reported on: 15 May, 2026
Avoro Capital Advisors LLC Annual Return Estimates Vs S&P 500
Our best estimate is that Avoro Capital Advisors LLC made a return of 4.02% in the last quarter. In trailing 12 months, it's portfolio return was 66.36%.
- Performance
- S&P 500
New Buys
| Ticker | $ Bought |
|---|---|
| cytokinetics inc | 219,700,000 |
| damora therapeutics inc | 97,979,700 |
| definium therapeutics inc | 94,500,000 |
| avalo therapeutics | 21,051,300 |
New stocks bought by Avoro Capital Advisors LLC
Additions
| Ticker | % Inc. |
|---|---|
| terns pharmaceuticals inc | 30.92 |
| ocular therapeutix inc | 14.26 |
| celcuity inc | 8.48 |
| revolution medicines inc | 8.04 |
| xenon pharmaceuticals inc | 6.51 |
| argenx se | 1.01 |
| united therapeutics corp | 0.92 |
| arrowhead pharmaceuticals inc | 0.71 |
Additions to existing portfolio by Avoro Capital Advisors LLC
Reductions
| Ticker | % Reduced |
|---|---|
| mannkind corp | -50.5 |
| lexeo therapeutics inc | -43.18 |
| centessa pharmaceuticals plc | -21.47 |
| soleno therapeutics inc | -20.69 |
| alkermes plc | -14.29 |
| uniqure nv | -3.1 |
| ascendis pharma | -0.95 |
Avoro Capital Advisors LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| avidity biosciences inc | -393,469,000 |
| mind medicine (mindmed) inc | -66,950,000 |
| spdr series trust - s&p biotech | -256,053,000 |
| oruka therapeutics inc | -40,413,500 |
| ptc therapeutics inc | -52,032,600 |
| apogee therapeutics inc | -37,740,000 |
| incyte corp | -13,334,000 |
Avoro Capital Advisors LLC got rid off the above stocks
Sector Distribution
Avoro Capital Advisors LLC has about 76.7% of it's holdings in Healthcare sector.
- Healthcare
- Others
| Sector | % |
|---|---|
| Healthcare | 76.7 |
| Others | 23.3 |
Market Cap. Distribution
Avoro Capital Advisors LLC has about 27% of it's portfolio invested in the large-cap and mega-cap stocks.
- MID-CAP
- LARGE-CAP
- UNALLOCATED
- SMALL-CAP
| Category | % |
|---|---|
| MID-CAP | 45.4 |
| LARGE-CAP | 27 |
| UNALLOCATED | 23.3 |
| SMALL-CAP | 3 |
Stocks belong to which Index?
About 44.8% of the stocks held by Avoro Capital Advisors LLC either belong to S&P 500 or RUSSELL 2000 index.
- Others
- RUSSELL 2000
| Index | % |
|---|---|
| Others | 55.2 |
| RUSSELL 2000 | 44.8 |
Avoro Capital Advisors LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Avoro Capital Advisors LLC
Avoro Capital Advisors LLC has 30 stocks in it's portfolio. About 76.4% of the portfolio is in top 10 stocks. proved to be the most loss making stock for the portfolio. UTHR was the most profitable stock for Avoro Capital Advisors LLC last quarter.
Last Reported on: 15 May, 2026| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| AADI | whitehawk therapeutics inc | 0.10 | 2,849,400 | 9,830,440 | unchanged | 0.00 | ||
| ALKS | alkermes plc | 0.42 | 1,200,000 | 42,432,000 | reduced | -14.29 | ||
| APLS | apellis pharmaceuticals inc | 4.84 | 12,222,200 | 491,700,000 | unchanged | 0.00 | ||
| ARGX | argenx se | 7.18 | 1,000,000 | 730,250,000 | added | 1.01 | ||
| ARWR | arrowhead pharmaceuticals inc | 6.60 | 10,700,000 | 670,890,000 | added | 0.71 | ||
| ASND | ascendis pharma | 11.39 | 5,062,500 | 1,157,950,000 | reduced | -0.95 | ||
| AVTX | avalo therapeutics | 0.21 | 1,410,000 | 21,051,300 | new | |||
| BIL | spdr series trust - s&p biotech | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| CELC | celcuity inc | 3.79 | 3,375,000 | 385,222,000 | added | 8.48 | ||
| CNTA | centessa pharmaceuticals plc | 4.47 | 11,430,500 | 454,018,000 | reduced | -21.47 | ||
| CYTK | cytokinetics inc | 2.16 | 3,333,330 | 219,700,000 | new | |||
| GHRS | gh research plc | 0.25 | 1,800,000 | 25,308,000 | unchanged | 0.00 | ||
| GLTO | damora therapeutics inc | 0.96 | 3,783,000 | 97,979,700 | new | |||
| INCY | incyte corp | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| KRYS | krystal biotech inc | 7.34 | 2,888,890 | 746,258,000 | unchanged | 0.00 | ||
| KYMR | kymera therapeutics inc | 6.12 | 7,474,750 | 622,572,000 | unchanged | 0.00 | ||
| MDGL | madrigal pharmaceuticals inc | 9.36 | 1,818,180 | 951,763,000 | added | 0.59 | ||
| MNKD | mannkind corp | 0.05 | 2,200,000 | 5,390,000 | reduced | -50.5 | ||
| MNMD | mind medicine (mindmed) inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| OCUL | ocular therapeutix inc | 1.03 | 12,315,000 | 104,308,000 | added | 14.26 | ||