Latest Caligan Partners LP Stock Portfolio

$2.13Billion | No. of Holdings #25

Caligan Partners LP Performance

2026 Q2+38.19%

YTD+42.94%

2025+136.83%

About Caligan Partners LP and 13F Hedge Fund Stock Holdings

On 2026-08-14, the fund reported it's updated stock portfolio. In the 13F Holdings report, Caligan Partners LP reported an equity portfolio of $2.1 Billions as of 30 Jun, 2026. <br><br> The top stock holdings of Caligan Partners LP are LQDA, RVMD, . The fund has invested 30.4% of it's portfolio in LIQUIDIA CORPORATION and 17.3% of portfolio in REVOLUTION MEDICINES INC. <br><br> The fund managers got completely rid off MINERALYS THERAPEUTICS INC, SPYRE THERAPEUTICS INC (AGLE) and XILIO THERAPEUTICS INC (XLO) stocks. They significantly reduced their stock positions in MBX BIOSCIENCES INC, TYRA BIOSCIENCES INC (TYRA) and XENON PHARMACEUTICALS INC (XENE). Caligan Partners LP opened new stock positions in IMMUNOCORE HLDGS PLC (IMCR), VIRIDIAN THERAPEUTICS INC (VRDN) and SAGIMET BIOSCIENCES INC. The fund showed a lot of confidence in some stocks as they added substantially to AURA BIOSCIENCES INC (AURA), FAETH THERAPEUTICS INC (SNSE) and AVALO THERAPEUTICS INC (AVTX).

Caligan Partners LP Equity Portfolio Value

Last Reported on: 14 Aug, 2026

$2.13Billion

as of Aug 14, 2026

Caligan Partners LP Annual Return Estimates Vs S&P 500

Our best estimate is that Caligan Partners LP made a return of 38.19% in the last quarter. In trailing 12 months, it's portfolio return was 193.52%.

Performance
S&P 500

New Buys

Ticker	$ Bought
immunocore hldgs plc	43,856,800
viridian therapeutics inc	40,303,400
sagimet biosciences inc	19,325,000
artiva biotherapeutics inc	16,840,300
cellectar biosciences inc	1,306,590

New stocks bought by Caligan Partners LP

Additions

Ticker	% Inc.
aura biosciences inc	1,769
faeth therapeutics inc	399
avalo therapeutics inc	93.51
inventiva sa	64.09
adma biologics inc	20.36
revolution medicines inc	18.69
abivax sa	6.57
vaxcyte inc	6.21

Additions to existing portfolio by Caligan Partners LP

Reductions

Ticker	% Reduced
mbx biosciences inc	-76.43
tyra biosciences inc	-36.8
xenon pharmaceuticals inc	-36.11

Caligan Partners LP reduced stake in above stock

Sold off

Ticker	$ Sold
mineralys therapeutics inc	-75,111,200
spyre therapeutics inc	-44,292,700
maze therapeutics inc	-18,356,600
xilio therapeutics inc	-942,996

Caligan Partners LP got rid off the above stocks

Sector Distribution

Caligan Partners LP has about 81.8% of it's holdings in Healthcare sector.

Healthcare
Others

Sector	%
Healthcare	81.8
Others	18.2

Market Cap. Distribution

Caligan Partners LP has about 21.8% of it's portfolio invested in the large-cap and mega-cap stocks.

MID-CAP
LARGE-CAP
UNALLOCATED
SMALL-CAP
MICRO-CAP

Category	%
MID-CAP	48
LARGE-CAP	21.8
UNALLOCATED	18.2
SMALL-CAP	7.2
MICRO-CAP	4

Stocks belong to which Index?

About 68.8% of the stocks held by Caligan Partners LP either belong to S&P 500 or RUSSELL 2000 index.

RUSSELL 2000
Others

Index	%
RUSSELL 2000	68.8
Others	31.2

Top 5 Winners (%)		%
LQDA	liquidia corporation	111.3 %
RVMD	revolution medicines inc	79.5 %
	mbx biosciences inc	52.5 %
TNGX	tango therapeutics inc	48.1 %
	lb pharmaceuticals inc	34.8 %

Top 5 Winners ($)		$
LQDA	liquidia corporation	340.9 M
RVMD	revolution medicines inc	162.7 M
	abivax sa	33.1 M
TNGX	tango therapeutics inc	25.4 M
EXEL	exelixis inc	17.9 M

Top 5 Losers (%)		%
IVA	inventiva sa	-27.4 %
TYRA	tyra biosciences inc	-13.6 %
SNSE	faeth therapeutics inc	-13.5 %
OCUP	opus genetics inc	-9.7 %
ADMA	adma biologics inc	-6.5 %

Top 5 Losers ($)		$
IVA	inventiva sa	-11.6 M
TYRA	tyra biosciences inc	-6.6 M
ADMA	adma biologics inc	-3.4 M
OCUP	opus genetics inc	-2.7 M
SNSE	faeth therapeutics inc	-2.5 M

Caligan Partners LP Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Caligan Partners LP

Caligan Partners LP has 25 stocks in it's portfolio. About 80.9% of the portfolio is in top 10 stocks. IVA proved to be the most loss making stock for the portfolio. LQDA was the most profitable stock for Caligan Partners LP last quarter.

$2.07BTotal Value

29.00Positions

14 Aug, 2026Last Reported

Current holdings of Current Stock Holdings of Caligan Partners LP, last reported on 14 Aug, 2026. Select a row with a linked ticker to view its historical trend.
Holdingsorted ascending	% Portfolio	Shares Held	$ Value	% Change
ADMA Adma Biologics Inc Adma Biologics IncADMA Caligan Partners LP's holding in Adma Biologics Inc over time	2.25%	5,725,010	$47.92M 2.25%	increased 20.36 percentadded

AGLE Spyre Therapeutics Inc Spyre Therapeutics IncAGLE Caligan Partners LP's holding in Spyre Therapeutics Inc over time	0%	0.00	$0.00 0%	decreased 100 percentsold off

ANIK Anika Therapeutics Inc Anika Therapeutics IncANIK Caligan Partners LP's holding in Anika Therapeutics Inc over time	0.99%	1,435,130	$21.00M 0.99%	unchanged 0 percentunchanged

AURA Aura Biosciences Inc Aura Biosciences IncAURA Caligan Partners LP's holding in Aura Biosciences Inc over time	1.44%	4,298,250	$30.52M 1.44%	increased 1769.91 percentadded

AVTX Avalo Therapeutics Inc Avalo Therapeutics IncAVTX Caligan Partners LP's holding in Avalo Therapeutics Inc over time	2.75%	3,163,870	$58.47M 2.75%	increased 93.51 percentadded

CLRB Cellectar Biosciences Inc Cellectar Biosciences IncCLRB Caligan Partners LP's holding in Cellectar Biosciences Inc over time	0.06%	469,998	$1.31M 0.06%	new position

EXEL Exelixis Inc Exelixis IncEXEL Caligan Partners LP's holding in Exelixis Inc over time	3.98%	1,553,260	$84.51M 3.98%	unchanged 0 percentunchanged

IMCR Immunocore Hldgs Plc Immunocore Hldgs Plc IMCR Caligan Partners LP's holding in Immunocore Hldgs Plc over time	2.06%	1,381,320	$43.86M 2.06%	new position

IVA Inventiva Sa Inventiva Sa IVA Caligan Partners LP's holding in Inventiva Sa over time	1.45%	8,163,190	$30.86M 1.45%	increased 64.09 percentadded

LQDA Liquidia Corporation Liquidia CorporationLQDA Caligan Partners LP's holding in Liquidia Corporation over time	30.45%	8,118,890	$647.32M 30.45%	unchanged 0 percentunchanged

OCUP Opus Genetics Inc Opus Genetics IncOCUP Caligan Partners LP's holding in Opus Genetics Inc over time	1.18%	6,077,080	$24.98M 1.18%	increased 0.03 percentadded

PCVX Vaxcyte Inc Vaxcyte IncPCVX Caligan Partners LP's holding in Vaxcyte Inc over time	5.98%	2,188,640	$127.22M 5.98%	increased 6.21 percentadded

RVMD Revolution Medicines Inc Revolution Medicines IncRVMD Caligan Partners LP's holding in Revolution Medicines Inc over time	17.28%	1,961,800	$367.40M 17.28%	increased 18.69 percentadded

SABS Sab Biotherapeutics Inc Sab Biotherapeutics IncSABS Caligan Partners LP's holding in Sab Biotherapeutics Inc over time	1.46%	7,967,210	$31.07M 1.46%	unchanged 0 percentunchanged

SNSE Faeth Therapeutics Inc Faeth Therapeutics IncSNSE Caligan Partners LP's holding in Faeth Therapeutics Inc over time	0.74%	629,467	$15.74M 0.74%	increased 399.57 percentadded

TNGX Tango Therapeutics Inc Tango Therapeutics IncTNGX Caligan Partners LP's holding in Tango Therapeutics Inc over time	3.68%	2,500,100	$78.15M 3.68%	increased 3.79 percentadded

TYRA Tyra Biosciences Inc Tyra Biosciences IncTYRA Caligan Partners LP's holding in Tyra Biosciences Inc over time	1.21%	806,986	$25.78M 1.21%	decreased 36.8 percentreduced

VOR Vor Biopharma Inc Vor Biopharma IncVOR Caligan Partners LP's holding in Vor Biopharma Inc over time	1.67%	1,925,070	$35.44M 1.67%	unchanged 0 percentunchanged

VRCA Verrica Pharmaceuticals Inc Verrica Pharmaceuticals IncVRCA Caligan Partners LP's holding in Verrica Pharmaceuticals Inc over time	0.27%	923,910	$5.65M 0.27%	unchanged 0 percentunchanged

VRDN Viridian Therapeutics Inc Viridian Therapeutics IncVRDN Caligan Partners LP's holding in Viridian Therapeutics Inc over time	1.9%	2,193,980	$40.30M 1.9%	new position