Latest Patient Square Capital LP Stock Portfolio
Patient Square Capital LP Performance:
2025 Q4: 22.69%YTD: 58.45%2024: -11.56%
Performance for 2025 Q4 is 22.69%, and YTD is 58.45%, and 2024 is -11.56%.
About Patient Square Capital LP and 13F Hedge Fund Stock Holdings
On 2026-02-12, the fund reported it's updated stock portfolio. In the 13F Holdings report, Patient Square Capital LP reported an equity portfolio of $467.1 Millions as of 31 Dec, 2025.
The top stock holdings of Patient Square Capital LP are ROIV, INSM, MIRM. The fund has invested 37.9% of it's portfolio in ROIVANT SCIENCES LTD and 9.9% of portfolio in INSMED INC.
The fund managers got completely rid off CIDARA THERAPEUTICS INC (CDTX), AGIOS PHARMACEUTICALS INC (AGIO) and UNIQURE NV (QURE) stocks. They significantly reduced their stock positions in LIQUIDIA CORPORATION (LQDA), ROIVANT SCIENCES LTD (ROIV) and OCULAR THERAPEUTIX INC (OCUL). Patient Square Capital LP opened new stock positions in BEONE MEDICINES LTD (BGNE), TERNS PHARMACEUTICALS INC (TERN) and COGENT BIOSCIENCES INC (COGT). The fund showed a lot of confidence in some stocks as they added substantially to PERSPECTIVE THERAPEUTICS INC, AVALO THERAPEUTICS INC (AVTX) and MIRUM PHARMACEUTICALS INC (MIRM).
The top stock holdings of Patient Square Capital LP are ROIV, INSM, MIRM. The fund has invested 37.9% of it's portfolio in ROIVANT SCIENCES LTD and 9.9% of portfolio in INSMED INC.
The fund managers got completely rid off CIDARA THERAPEUTICS INC (CDTX), AGIOS PHARMACEUTICALS INC (AGIO) and UNIQURE NV (QURE) stocks. They significantly reduced their stock positions in LIQUIDIA CORPORATION (LQDA), ROIVANT SCIENCES LTD (ROIV) and OCULAR THERAPEUTIX INC (OCUL). Patient Square Capital LP opened new stock positions in BEONE MEDICINES LTD (BGNE), TERNS PHARMACEUTICALS INC (TERN) and COGENT BIOSCIENCES INC (COGT). The fund showed a lot of confidence in some stocks as they added substantially to PERSPECTIVE THERAPEUTICS INC, AVALO THERAPEUTICS INC (AVTX) and MIRUM PHARMACEUTICALS INC (MIRM).
Patient Square Capital LP Annual Return Estimates Vs S&P 500
Our best estimate is that Patient Square Capital LP made a return of 22.69% in the last quarter. In trailing 12 months, it's portfolio return was 58.45%.
- Performance
- S&P 500
New Buys
| Ticker | $ Bought |
|---|---|
| beone medicines ltd | 21,057,700 |
| terns pharmaceuticals inc | 12,928,000 |
| cogent biosciences inc | 11,273,100 |
| dbv technologies s a | 6,882,990 |
| xenon pharmaceuticals inc | 6,117,930 |
| arcutis biotherapeutics inc | 6,098,400 |
| spyre therapeutics inc | 4,914,000 |
| arcus biosciences inc | 4,051,100 |
New stocks bought by Patient Square Capital LP
Additions
| Ticker | % Inc. |
|---|---|
| perspective therapeutics inc | 224 |
| avalo therapeutics inc | 211 |
| mirum pharmaceuticals inc | 186 |
| argenx se | 67.74 |
| allogene therapeutics inc | 66.49 |
| pharvaris n v | 57.13 |
| kymera therapeutics inc | 50.12 |
| enliven therapeutics inc | 22.84 |
Additions to existing portfolio by Patient Square Capital LP
Reductions
| Ticker | % Reduced |
|---|---|
| liquidia corporation | -43.25 |
| roivant sciences ltd | -34.57 |
| ocular therapeutix inc | -31.47 |
| eyepoint inc | -22.91 |
| insmed inc | -18.2 |
| abivax sa | -14.38 |
| assembly biosciences inc | -6.05 |
Patient Square Capital LP reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| geron corp | -1,157,650 |
| nurix therapeutics inc | -4,040,070 |
| agios pharmaceuticals inc | -5,371,820 |
| cidara therapeutics inc | -11,587,000 |
| uniqure nv | -4,377,750 |
Patient Square Capital LP got rid off the above stocks
Sector Distribution
Patient Square Capital LP has about 84.1% of it's holdings in Healthcare sector.
- Healthcare
- Others
| Sector | % |
|---|---|
| Healthcare | 84.1 |
| Others | 15.9 |
Market Cap. Distribution
Patient Square Capital LP has about 52.4% of it's portfolio invested in the large-cap and mega-cap stocks.
- LARGE-CAP
- MID-CAP
- UNALLOCATED
- SMALL-CAP
- MEGA-CAP
- MICRO-CAP
| Category | % |
|---|---|
| LARGE-CAP | 47.9 |
| MID-CAP | 22.8 |
| UNALLOCATED | 15.9 |
| SMALL-CAP | 7.7 |
| MEGA-CAP | 4.5 |
| MICRO-CAP | 1.2 |
Stocks belong to which Index?
About 35.7% of the stocks held by Patient Square Capital LP either belong to S&P 500 or RUSSELL 2000 index.
- Others
- RUSSELL 2000
| Index | % |
|---|---|
| Others | 64.3 |
| RUSSELL 2000 | 35.7 |
Patient Square Capital LP Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Patient Square Capital LP
Patient Square Capital LP has 28 stocks in it's portfolio. About 77.5% of the portfolio is in top 10 stocks. proved to be the most loss making stock for the portfolio. ROIV was the most profitable stock for Patient Square Capital LP last quarter.
Last Reported on: 12 Feb, 2026| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| AGIO | agios pharmaceuticals inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| AGLE | spyre therapeutics inc | 1.05 | 150,000 | 4,914,000 | new | |||
| ALLO | allogene therapeutics inc | 1.46 | 4,963,760 | 6,800,350 | added | 66.49 | ||
| AMLX | amylyx pharmaceuticals inc | 0.90 | 350,000 | 4,228,000 | added | 10.65 | ||
| ARGX | argenx se | 4.68 | 26,000 | 21,864,700 | added | 67.74 | ||
| ARQT | arcutis biotherapeutics inc | 1.30 | 210,000 | 6,098,400 | new | |||
| ASMB | assembly biosciences inc | 0.92 | 127,000 | 4,319,270 | reduced | -6.05 | ||
| AVTX | avalo therapeutics inc | 1.21 | 311,966 | 5,665,300 | added | 211 | ||
| BGNE | beone medicines ltd | 4.51 | 69,312 | 21,057,700 | new | |||
| CDTX | cidara therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| CELC | celcuity inc | 2.56 | 120,000 | 11,968,800 | added | 20.00 | ||
| COGT | cogent biosciences inc | 2.41 | 317,372 | 11,273,100 | new | |||
| DBVT | dbv technologies s a | 1.47 | 359,050 | 6,882,990 | new | |||
| EYPT | eyepoint inc | 3.05 | 780,000 | 14,250,600 | reduced | -22.91 | ||
| GERN | geron corp | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| HROW | harrow inc | 0.07 | 7,031 | 344,519 | new | |||
| INSM | insmed inc | 9.95 | 267,000 | 46,468,700 | reduced | -18.2 | ||
| KYMR | kymera therapeutics inc | 2.32 | 139,000 | 10,815,600 | added | 50.12 | ||
| LQDA | liquidia corporation | 1.68 | 227,000 | 7,829,230 | reduced | -43.25 | ||
| MIRM | mirum pharmaceuticals inc | 5.05 | 298,682 | 23,592,900 | added | 186 | ||