Latest Propel Bio Management, LLC Stock Portfolio
Propel Bio Management, LLC Performance:
2025 Q4: 12.19%YTD: 17.61%2024: -29.17%
Performance for 2025 Q4 is 12.19%, and YTD is 17.61%, and 2024 is -29.17%.
About Propel Bio Management, LLC and 13F Hedge Fund Stock Holdings
On 2026-02-11, the fund reported it's updated stock portfolio. In the 13F Holdings report, Propel Bio Management, LLC reported an equity portfolio of $117.1 Millions as of 31 Dec, 2025.
The top stock holdings of Propel Bio Management, LLC are PAGP, ACHV, PHAT. The fund has invested 20.8% of it's portfolio in PLAINS GP HLDGS L P and 16.1% of portfolio in ACHIEVE LIFE SCIENCES INC.
The fund managers got completely rid off AKERO THERAPEUTICS INC (AKRO), APPLIED THERAPEUTICS INC (APLT) and TSCAN THERAPEUTICS INC (TCRX) stocks. They significantly reduced their stock positions in ZEVRA THERAPEUTICS INC, MILESTONE PHARMACEUTICALS (MIST) and ABEONA THERAPEUTICS INC (ABEO). Propel Bio Management, LLC opened new stock positions in KYVERNA THERAPEUTICS INC, INVENTIVA SA - ADR (IVA) and SAB BIOTHERAPEUTICS INC (SABS). The fund showed a lot of confidence in some stocks as they added substantially to VIRIDIAN THERAPEUTICS INC (VRDN), NEKTAR THERAPEUTICS (NKTR) and COMPASS PATHWAYS PLC (CMPS).
The top stock holdings of Propel Bio Management, LLC are PAGP, ACHV, PHAT. The fund has invested 20.8% of it's portfolio in PLAINS GP HLDGS L P and 16.1% of portfolio in ACHIEVE LIFE SCIENCES INC.
The fund managers got completely rid off AKERO THERAPEUTICS INC (AKRO), APPLIED THERAPEUTICS INC (APLT) and TSCAN THERAPEUTICS INC (TCRX) stocks. They significantly reduced their stock positions in ZEVRA THERAPEUTICS INC, MILESTONE PHARMACEUTICALS (MIST) and ABEONA THERAPEUTICS INC (ABEO). Propel Bio Management, LLC opened new stock positions in KYVERNA THERAPEUTICS INC, INVENTIVA SA - ADR (IVA) and SAB BIOTHERAPEUTICS INC (SABS). The fund showed a lot of confidence in some stocks as they added substantially to VIRIDIAN THERAPEUTICS INC (VRDN), NEKTAR THERAPEUTICS (NKTR) and COMPASS PATHWAYS PLC (CMPS).
Propel Bio Management, LLC Annual Return Estimates Vs S&P 500
Our best estimate is that Propel Bio Management, LLC made a return of 12.19% in the last quarter. In trailing 12 months, it's portfolio return was 17.61%.
- Performance
- S&P 500
New Buys
| Ticker | $ Bought |
|---|---|
| kyverna therapeutics inc | 6,266,660 |
| inventiva sa - adr | 4,650,000 |
| oculis holding ag | 3,451,600 |
| sab biotherapeutics inc | 2,441,780 |
| regenxbio inc | 1,683,300 |
| lenz therapeutics inc | 945,360 |
| aardvark therapeutics inc | 609,105 |
| kalaris therapeutics inc | 354,927 |
New stocks bought by Propel Bio Management, LLC
Additions
| Ticker | % Inc. |
|---|---|
| viridian therapeutics inc | 213 |
| nektar therapeutics | 69.02 |
| compass pathways plc | 68.98 |
| phathom pharmaceuticals inc | 34.00 |
Additions to existing portfolio by Propel Bio Management, LLC
Reductions
| Ticker | % Reduced |
|---|---|
| zevra therapeutics inc | -72.54 |
| milestone pharmaceuticals | -19.64 |
| abeona therapeutics inc | -14.71 |
| celldex therapeutics inc | -0.45 |
Propel Bio Management, LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| applied therapeutics inc | -6,826,550 |
| tscan therapeutics inc | -3,516,790 |
| jasper therapeutics inc | -2,448,560 |
| akero therapeutics inc | -10,867,400 |
Propel Bio Management, LLC got rid off the above stocks
Sector Distribution
Propel Bio Management, LLC has about 64.8% of it's holdings in Healthcare sector.
- Healthcare
- Energy
- Others
| Sector | % |
|---|---|
| Healthcare | 64.8 |
| Energy | 20.8 |
| Others | 14.4 |
Market Cap. Distribution
Propel Bio Management, LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.
- MICRO-CAP
- SMALL-CAP
- MID-CAP
- UNALLOCATED
- NANO-CAP
| Category | % |
|---|---|
| MICRO-CAP | 34.6 |
| SMALL-CAP | 24.5 |
| MID-CAP | 24.4 |
| UNALLOCATED | 14.4 |
| NANO-CAP | 2.1 |
Stocks belong to which Index?
About 23% of the stocks held by Propel Bio Management, LLC either belong to S&P 500 or RUSSELL 2000 index.
- Others
- RUSSELL 2000
| Index | % |
|---|---|
| Others | 77 |
| RUSSELL 2000 | 23 |
Propel Bio Management, LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Propel Bio Management, LLC
Propel Bio Management, LLC has 20 stocks in it's portfolio. About 83.9% of the portfolio is in top 10 stocks. NKTR proved to be the most loss making stock for the portfolio. ACHV was the most profitable stock for Propel Bio Management, LLC last quarter.
Last Reported on: 11 Feb, 2026| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ABEO | abeona therapeutics inc | 3.74 | 830,780 | 4,378,210 | reduced | -14.71 | ||
| ACHV | achieve life sciences inc | 16.07 | 3,786,420 | 18,818,500 | unchanged | 0.00 | ||
| AKRO | akero therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| APLT | applied therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ATHA | athira pharma inc | 0.96 | 149,279 | 1,130,040 | unchanged | 0.00 | ||
| CLDX | celldex therapeutics inc | 3.58 | 154,300 | 4,190,790 | reduced | -0.45 | ||
| CMPS | compass pathways plc | 5.08 | 861,778 | 5,946,270 | added | 68.98 | ||
| DCTH | delcath systems inc | 3.78 | 438,509 | 4,428,940 | unchanged | 0.00 | ||
| IVA | inventiva sa - adr | 3.97 | 1,000,000 | 4,650,000 | new | |||
| JSPR | jasper therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| MIST | milestone pharmaceuticals | 7.10 | 4,118,320 | 8,319,010 | reduced | -19.64 | ||
| NKTR | nektar therapeutics | 2.99 | 82,822 | 3,501,710 | added | 69.02 | ||
| PAGP | plains gp hldgs l p | 20.79 | 1,272,360 | 24,353,000 | unchanged | 0.00 | ||
| PHAT | phathom pharmaceuticals inc | 10.49 | 740,918 | 12,291,800 | added | 34.00 | ||
| RGNX | regenxbio inc | 1.44 | 116,896 | 1,683,300 | new | |||
| SABS | sab biotherapeutics inc | 2.08 | 652,881 | 2,441,780 | new | |||
| TCRX | tscan therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| VRDN | viridian therapeutics inc | 7.51 | 282,531 | 8,792,360 | added | 213 | ||
| kyverna therapeutics inc | 5.35 | 666,666 | 6,266,660 | new | ||||
| oculis holding ag | 2.95 | 172,839 | 3,451,600 | new | ||||