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Date

Name

Buy/Sell

$ Value

# Shares

Avg. Price

Title

Chief Technology Officer

Chief Legal Officer

Chief Medical Officer

Interim CEO, President and CFO

President & CEO

See Remarks

Chief Financial Officer

AVROBIO, Inc., a clinical-stage gene therapy company, develops ex vivo lentiviral-based gene therapies to treat rare diseases following a single dose worldwide. Its gene therapies employ hematopoietic stem cells that are harvested from the patient and then modified with a lentiviral vector to insert the equivalent of a functional copy of the gene that is mutated in the target disease. The company's pipeline includes AVR-RD-02, which is in phase 1/2 clinical trial for the treatment of Gaucher disease type 1, as well as to treat Gaucher disease type 3; AVR-RD-03 that is in preclinical stage for the treatment of Pompe disease; AVR-RD-04, which is in phase 1/2 clinical trial for the treatment of cystinosis; and AVR-RD-05 that is in preclinical stage for the treatment of Hunter syndrome. The company was incorporated in 2015 and is headquartered in Cambridge, Massachusetts.

AVROBIO, Inc., a clinical-stage gene therapy company, develops ex vivo lentiviral-based gene therapies to treat rare diseases following a ...

Datesorted ascending	Name	Buy/Sell	$ Value	# Shares	Avg. Price	Title
2024-02-05	Premium	sold (taxes)	Premium	Premium	Premium	Chief Technology Officer
2024-02-05	Premium	sold (taxes)	Premium	Premium	Premium	Chief Legal Officer
2024-02-05	Premium	sold (taxes)	Premium	Premium	Premium	Chief Medical Officer
2024-02-05	Premium	sold (taxes)	Premium	Premium	Premium	Interim CEO, President and CFO
2024-02-01	Premium	acquired	Premium	Premium	Premium	Chief Legal Officer
2024-02-01	Premium	acquired	Premium	Premium	Premium	Interim CEO, President and CFO
2024-02-01	Premium	acquired	Premium	Premium	Premium	Chief Medical Officer
2024-02-01	Premium	acquired	Premium	Premium	Premium	Chief Technology Officer
2023-06-12	Premium	sold (taxes)	Premium	Premium	Premium	Chief Technology Officer
2023-01-24	Premium	acquired	Premium	Premium	Premium	President & CEO
2022-12-28	Premium	gifted	Premium	Premium	Premium	President & CEO
2022-12-28	Premium	gifted	Premium	Premium	Premium	President & CEO
2022-12-23	Premium	acquired	Premium	Premium	Premium	President & CEO
2021-07-07	Premium	bought	Premium	Premium	Premium	-
2021-02-17	Premium	bought	Premium	Premium	Premium	-
2020-12-24	Premium	acquired	Premium	Premium	Premium	President & CEO
2020-02-13	Premium	sold	Premium	Premium	Premium	-
2020-02-12	Premium	sold	Premium	Premium	Premium	See Remarks
2020-02-11	Premium	sold	Premium	Premium	Premium	-
2020-02-11	Premium	sold	Premium	Premium	Premium	See Remarks
2020-01-28	Premium	sold	Premium	Premium	Premium	-
2019-07-29	Premium	gifted	Premium	Premium	Premium	See Remarks
2019-07-19	Premium	bought	Premium	Premium	Premium	-
2019-07-19	Premium	bought	Premium	Premium	Premium	-
2019-05-20	Premium	sold	Premium	Premium	Premium	-

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