Latest ORACLE INVESTMENT MANAGEMENT INC Stock Portfolio

$167Million | No. of Holdings #17

ORACLE INVESTMENT MANAGEMENT INC Performance

2025 Q4+12.31%

YTD+26.18%

2024+45.21%

About ORACLE INVESTMENT MANAGEMENT INC and 13F Hedge Fund Stock Holdings

ORACLE INVESTMENT MANAGEMENT INC is a hedge fund based in Greenwich, CT. On 2026-02-18, the fund reported it's updated stock portfolio. In the 13F Holdings report, ORACLE INVESTMENT MANAGEMENT INC reported an equity portfolio of $167.9 Millions as of 31 Dec, 2025. <br><br> The top stock holdings of ORACLE INVESTMENT MANAGEMENT INC are SMFR, ARDX, . The fund has invested 68.5% of it's portfolio in GENEDX HOLDINGS CORP and 6.5% of portfolio in ARDELYX INC. <br><br> The fund managers got completely rid off PALANTIR TECHNOLOGIES INC (PLTR), CENTENE CORP DEL (CNC) and NOVAVAX INC (NVAX) stocks. They significantly reduced their stock positions in TELADOC HEALTH INC (TDOC) and GENEDX HOLDINGS CORP (SMFR). ORACLE INVESTMENT MANAGEMENT INC opened new stock positions in TAYSHA GENE THERAPIES INC (TSHA), EDGEWISE THERAPEUTICS INC (EWTX) and DAY ONE BIOPHARMACEUTICALS I (DAWN). The fund showed a lot of confidence in some stocks as they added substantially to PERSONALIS INC (PSNL), ARDELYX INC (ARDX) and BIOHAVEN LTD.

ORACLE INVESTMENT MANAGEMENT INC Equity Portfolio Value

Last Reported on: 18 Feb, 2026

$167Million

as of Feb 18, 2026

ORACLE INVESTMENT MANAGEMENT INC Annual Return Estimates Vs S&P 500

Our best estimate is that ORACLE INVESTMENT MANAGEMENT INC made a return of 12.31% in the last quarter. In trailing 12 months, it's portfolio return was 26.18%.

Performance
S&P 500

New Buys

Ticker	$ Bought
taysha gene therapies inc	1,457,500
edgewise therapeutics inc	951,482
day one biopharmaceuticals i	932,000
ark etf tr	564,915
tempus ai inc	384,238
hertz global hldgs inc	77,100

New stocks bought by ORACLE INVESTMENT MANAGEMENT INC

Additions

Ticker	% Inc.
personalis inc	47.9
ardelyx inc	24.52
biohaven ltd	4.35
sangamo therapeutics inc	3.09

Additions to existing portfolio by ORACLE INVESTMENT MANAGEMENT INC

Reductions

Ticker	% Reduced
teladoc health inc	-49.77
genedx holdings corp	-0.6

ORACLE INVESTMENT MANAGEMENT INC reduced stake in above stock

Sold off

Ticker	$ Sold
novavax inc	-2,106,810
centene corp del	-3,935,500
palantir technologies inc	-5,381,390
kraneshares trust	-718,592
biodesix inc	-113,250

ORACLE INVESTMENT MANAGEMENT INC got rid off the above stocks

Sector Distribution

ORACLE INVESTMENT MANAGEMENT INC has about 75.4% of it's holdings in sector.

Healthcare
Others

Sector	%
	75.4
Healthcare	17.4
Others	7

Market Cap. Distribution

ORACLE INVESTMENT MANAGEMENT INC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.

MID-CAP
SMALL-CAP
UNALLOCATED
MICRO-CAP

Category	%
MID-CAP	76
SMALL-CAP	14.4
UNALLOCATED	7
MICRO-CAP	2.2

Stocks belong to which Index?

About 8.7% of the stocks held by ORACLE INVESTMENT MANAGEMENT INC either belong to S&P 500 or RUSSELL 2000 index.

Others
RUSSELL 2000

Index	%
Others	90.9
RUSSELL 2000	8.7

Top 5 Winners (%)		%
BIIB	biogen inc	25.6 %
SMFR	genedx holdings corp	20.6 %
PSNL	personalis inc	17.9 %
ARDX	ardelyx inc	5.2 %
TSLA	tesla inc	1.1 %

Top 5 Winners ($)		$
SMFR	genedx holdings corp	19.8 M
ARDX	ardelyx inc	0.5 M
PSNL	personalis inc	0.4 M
BIIB	biogen inc	0.1 M
TSLA	tesla inc	0.0 M

Top 5 Losers (%)		%
SGMO	sangamo therapeutics inc	-37.3 %
	biohaven ltd	-24.4 %
TDOC	teladoc health inc	-7.1 %
FORA	forian inc	-5.8 %
QDEL	quidelortho corp	-3.0 %

Top 5 Losers ($)		$
	biohaven ltd	-2.8 M
TDOC	teladoc health inc	-0.4 M
SGMO	sangamo therapeutics inc	-0.3 M
FORA	forian inc	-0.2 M
QDEL	quidelortho corp	-0.1 M

ORACLE INVESTMENT MANAGEMENT INC Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of ORACLE INVESTMENT MANAGEMENT INC

ORACLE INVESTMENT MANAGEMENT INC has 17 stocks in it's portfolio. About 89.1% of the portfolio is in top 10 stocks. proved to be the most loss making stock for the portfolio. SMFR was the most profitable stock for ORACLE INVESTMENT MANAGEMENT INC last quarter.

$152.60MTotal Value

22.00Positions

18 Feb, 2026Last Reported

Current holdings of Current Stock Holdings of ORACLE INVESTMENT MANAGEMENT INC, last reported on 18 Feb, 2026. Select a row with a linked ticker to view its historical trend.
Holdingsorted ascending	% Portfolio	Shares Held	$ Value	% Change
ARDX Ardelyx Inc Ardelyx IncARDX ORACLE INVESTMENT MANAGEMENT INC's holding in Ardelyx Inc over time	6.5%	1,872,620	$10.92M 6.5%	increased 24.52 percentadded

ARKF Ark Etf Tr Ark Etf Tr ARKF ORACLE INVESTMENT MANAGEMENT INC's holding in Ark Etf Tr over time	0.34%	19,500	$564.9K 0.34%	new position

BDSX Biodesix Inc Biodesix IncBDSX ORACLE INVESTMENT MANAGEMENT INC's holding in Biodesix Inc over time	0%	0.00	$0.00 0%	decreased 100 percentsold off

BIIB Biogen Inc Biogen IncBIIB ORACLE INVESTMENT MANAGEMENT INC's holding in Biogen Inc over time	0.25%	2,412	$424.5K 0.25%	unchanged 0 percentunchanged

BNDD Kraneshares Trust Kraneshares Trust BNDD ORACLE INVESTMENT MANAGEMENT INC's holding in Kraneshares Trust over time	0%	0.00	$0.00 0%	decreased 100 percentsold off

CNC Centene Corp Del Centene Corp DelCNC ORACLE INVESTMENT MANAGEMENT INC's holding in Centene Corp Del over time	0%	0.00	$0.00 0%	decreased 100 percentsold off

DAWN Day One Biopharmaceuticals I Day One Biopharmaceuticals IDAWN ORACLE INVESTMENT MANAGEMENT INC's holding in Day One Biopharmaceuticals I over time	0.56%	100,000	$932.0K 0.56%	new position

EWTX Edgewise Therapeutics Inc Edgewise Therapeutics IncEWTX ORACLE INVESTMENT MANAGEMENT INC's holding in Edgewise Therapeutics Inc over time	0.57%	38,343	$951.5K 0.57%	new position

FORA Forian Inc Forian IncFORA ORACLE INVESTMENT MANAGEMENT INC's holding in Forian Inc over time	1.73%	1,366,110	$2.90M 1.73%	unchanged 0 percentunchanged

HTZ Hertz Global Hldgs Inc Hertz Global Hldgs IncHTZ ORACLE INVESTMENT MANAGEMENT INC's holding in Hertz Global Hldgs Inc over time	0.05%	15,000	$77.1K 0.05%	new position

NVAX Novavax Inc Novavax IncNVAX ORACLE INVESTMENT MANAGEMENT INC's holding in Novavax Inc over time	0%	0.00	$0.00 0%	decreased 100 percentsold off

PLTR Palantir Technologies Inc Palantir Technologies IncPLTR ORACLE INVESTMENT MANAGEMENT INC's holding in Palantir Technologies Inc over time	0%	0.00	$0.00 0%	decreased 100 percentsold off

PSNL Personalis Inc Personalis IncPSNL ORACLE INVESTMENT MANAGEMENT INC's holding in Personalis Inc over time	1.61%	339,343	$2.70M 1.61%	increased 47.9 percentadded

QDEL Quidelortho Corp Quidelortho CorpQDEL ORACLE INVESTMENT MANAGEMENT INC's holding in Quidelortho Corp over time	2.01%	118,291	$3.38M 2.01%	unchanged 0 percentunchanged

SGMO Sangamo Therapeutics Inc Sangamo Therapeutics IncSGMO ORACLE INVESTMENT MANAGEMENT INC's holding in Sangamo Therapeutics Inc over time	0.26%	1,035,740	$435.0K 0.26%	increased 3.09 percentadded

SMFR Genedx Holdings Corp Genedx Holdings CorpSMFR ORACLE INVESTMENT MANAGEMENT INC's holding in Genedx Holdings Corp over time	68.51%	884,654	$115.06M 68.51%	decreased 0.6 percentreduced

TDOC Teladoc Health Inc Teladoc Health IncTDOC ORACLE INVESTMENT MANAGEMENT INC's holding in Teladoc Health Inc over time	1.48%	354,338	$2.48M 1.48%	decreased 49.77 percentreduced

TSHA Taysha Gene Therapies Inc Taysha Gene Therapies IncTSHA ORACLE INVESTMENT MANAGEMENT INC's holding in Taysha Gene Therapies Inc over time	0.87%	265,000	$1.46M 0.87%	new position

TSLA Tesla Inc Tesla IncTSLA ORACLE INVESTMENT MANAGEMENT INC's holding in Tesla Inc over time	0.13%	500	$224.9K 0.13%	unchanged 0 percentunchanged

Com Biohaven Ltd Biohaven Ltd ORACLE INVESTMENT MANAGEMENT INC's holding in Biohaven Ltd over time	5.19%	772,181	$8.72M 5.19%	increased 4.35 percentadded