Explore our featured stock ideas and investment opportunities to make informed decisions in today's market.
View AllLatest Palo Alto Investors LP Stock Portfolio
$1.11Billion
Equity Portfolio Value
Last Reported on: 15 Feb, 2024
About Palo Alto Investors LP and it’s 13F Hedge Fund Stock Holdings
Palo Alto Investors LP is a hedge fund based in Palo Alto, CA. On 02-Jun-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $1.3 Billions. In it's latest 13F Holdings report, Palo Alto Investors LP reported an equity portfolio of $1.1 Billions as of 31 Dec, 2023.
The top stock holdings of Palo Alto Investors LP are INSM, FOLD, BMRN. The fund has invested 15.4% of it's portfolio in INSMED INC and 13.3% of portfolio in AMICUS THERAPEUTICS INC.
The fund managers got completely rid off KEZAR LIFE SCIENCES INC (KZR) and TACTILE SYSTEMS TECHNOLOGY I (TCMD) stocks. They significantly reduced their stock positions in GOSSAMER BIO INC (GOSS), TRAVERE THERAPEUTICS INC (TVTX) and UNITED THERAPEUTICS CORP (UTHR). Palo Alto Investors LP opened new stock positions in ALNYLAM PHARMACEUTICALS INC (ALNY), IOVANCE BIOTHERAPEUTICS INC (IOVA) and VERVE THERAPEUTICS INC (VERV). The fund showed a lot of confidence in some stocks as they added substantially to SAREPTA THERAPEUTICS INC (SRPT), NEVRO CORP (NVRO) and ANAPTYSBIO INC (ANAB).
The top stock holdings of Palo Alto Investors LP are INSM, FOLD, BMRN. The fund has invested 15.4% of it's portfolio in INSMED INC and 13.3% of portfolio in AMICUS THERAPEUTICS INC.
The fund managers got completely rid off KEZAR LIFE SCIENCES INC (KZR) and TACTILE SYSTEMS TECHNOLOGY I (TCMD) stocks. They significantly reduced their stock positions in GOSSAMER BIO INC (GOSS), TRAVERE THERAPEUTICS INC (TVTX) and UNITED THERAPEUTICS CORP (UTHR). Palo Alto Investors LP opened new stock positions in ALNYLAM PHARMACEUTICALS INC (ALNY), IOVANCE BIOTHERAPEUTICS INC (IOVA) and VERVE THERAPEUTICS INC (VERV). The fund showed a lot of confidence in some stocks as they added substantially to SAREPTA THERAPEUTICS INC (SRPT), NEVRO CORP (NVRO) and ANAPTYSBIO INC (ANAB).
New Buys
| Ticker | $ Bought |
|---|---|
| ALNYLAM PHARMACEUTICALS INC | 29,560,800 |
| IOVANCE BIOTHERAPEUTICS INC | 17,128,200 |
| VERVE THERAPEUTICS INC | 8,026,890 |
| BLUEBIRD BIO INC | 4,600,000 |
| VYNE THERAPEUTICS INC PIPE | 1,037,860 |
| TAYSHA GENE THERAPIES INC | 937,854 |
| SIGHT SCIENCES INC | 896,756 |
New stocks bought by Palo Alto Investors LP
Additions
| Ticker | % Inc. |
|---|---|
| SAREPTA THERAPEUTICS INC | 113 |
| NEVRO CORP | 93.98 |
| ANAPTYSBIO INC | 59.29 |
| ALDEYRA THERAPEUTICS INC | 40.21 |
| REVANCE THERAPEUTICS INC | 0.17 |
| ACADIA PHARMACEUTICALS INC | 0.16 |
| PROTHENA CORP PLC | 0.16 |
| STAAR SURGICAL CO | 0.15 |
Additions to existing portfolio by Palo Alto Investors LP
Reductions
| Ticker | % Reduced |
|---|---|
| TRAVERE THERAPEUTICS INC | -33.33 |
| UNITED THERAPEUTICS CORP | -31.28 |
| BIOMARIN PHARMACEUTICAL INC | -18.04 |
| NOVOCURE LTD | -14.9 |
| KARYOPHARM THERAPEUTICS INC | -10.11 |
| GOSSAMER BIO INC | -8.75 |
| INSMED INC | -6.41 |
| AMICUS THERAPEUTICS INC | -1.43 |
Palo Alto Investors LP reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| KEZAR LIFE SCIENCES INC | -780,878 |
| TACTILE SYSTEMS TECHNOLOGY I | -380,755 |
Palo Alto Investors LP got rid off the above stocks
Current Stock Holdings of Palo Alto Investors LP
Last Reported on: 15 Feb, 2024| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options |
|---|---|---|---|---|---|---|---|
| ACAD | ACADIA PHARMACEUTICALS INC | 6.80 | 2,409,560 | 75,443,200 | ADDED | 0.16 | |
| ALDX | ALDEYRA THERAPEUTICS INC | 0.07 | 225,465 | 791,382 | ADDED | 40.21 | |
| ALGN | ALIGN TECHNOLOGY INC | 1.38 | 55,705 | 15,263,200 | UNCHANGED | 0.00 | |
| ALKS | ALKERMES PLC | 1.51 | 603,400 | 16,738,300 | UNCHANGED | 0.00 | |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 2.66 | 154,437 | 29,560,800 | NEW | ||
| ANAB | ANAPTYSBIO INC | 1.33 | 686,882 | 14,713,000 | ADDED | 59.29 | |
| BIIB | BIOGEN INC | 8.87 | 380,417 | 98,440,500 | REDUCED | -0.23 | |
| BLUE | BLUEBIRD BIO INC | 0.41 | 3,333,330 | 4,600,000 | NEW | ||
| BMRN | BIOMARIN PHARMACEUTICAL INC | 13.04 | 1,500,750 | 144,702,000 | REDUCED | -18.04 | |
| CYTK | CYTOKINETICS INC | 0.84 | 111,717 | 9,327,250 | UNCHANGED | 0.00 | |
| EHTH | EHEALTH INC | 2.15 | 2,739,380 | 23,887,400 | UNCHANGED | 0.00 | |
| FOLD | AMICUS THERAPEUTICS INC | 13.26 | 10,373,700 | 147,203,000 | REDUCED | -1.43 | |
| GOSS | GOSSAMER BIO INC | 0.59 | 5,958,890 | 6,530,290 | REDUCED | -8.75 | |
| INSM | INSMED INC | 15.39 | 5,511,720 | 170,808,000 | REDUCED | -6.41 | |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 1.54 | 2,106,790 | 17,128,200 | NEW | ||
| KPTI | KARYOPHARM THERAPEUTICS INC | 0.40 | 5,102,190 | 4,413,400 | REDUCED | -10.11 | |
| KZR | KEZAR LIFE SCIENCES INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| MIRM | MIRUM PHARMACEUTICALS INC | 0.17 | 64,700 | 1,909,940 | UNCHANGED | 0.00 | |
| NVCR | NOVOCURE LTD | 0.76 | 561,908 | 8,389,290 | REDUCED | -14.9 | |
| NVRO | NEVRO CORP | 1.46 | 750,371 | 16,148,000 | ADDED | 93.98 | |
| PRTA | PROTHENA CORP PLC | 5.43 | 1,660,060 | 60,326,500 | ADDED | 0.16 | |
| RLMD | RELMADA THERAPEUTICS INC | 0.27 | 732,400 | 3,032,140 | UNCHANGED | 0.00 | |
| RVNC | REVANCE THERAPEUTICS INC | 4.15 | 5,237,280 | 46,035,700 | ADDED | 0.17 | |
| SAGE | SAGE THERAPEUTICS INC | 1.94 | 991,525 | 21,486,300 | REDUCED | -1.42 | |
| SGHT | SIGHT SCIENCES INC | 0.08 | 173,790 | 896,756 | NEW | ||
| SNDX | SYNDAX PHARMACEUTICALS INC | 0.92 | 472,600 | 10,212,900 | UNCHANGED | 0.00 | |
| SRPT | SAREPTA THERAPEUTICS INC | 1.75 | 200,905 | 19,373,300 | ADDED | 113 | |
| STAA | STAAR SURGICAL CO | 3.87 | 1,376,950 | 42,974,600 | ADDED | 0.15 | |
| TCMD | TACTILE SYSTEMS TECHNOLOGY I | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| TSHA | TAYSHA GENE THERAPIES INC | 0.08 | 529,861 | 937,854 | NEW | ||
| TVTX | TRAVERE THERAPEUTICS INC | 0.09 | 110,719 | 995,364 | REDUCED | -33.33 | |
| URGN | UROGEN PHARMA LTD | 0.03 | 24,500 | 367,500 | UNCHANGED | 0.00 | |
| UTHR | UNITED THERAPEUTICS CORP | 7.84 | 395,784 | 87,028,900 | REDUCED | -31.28 | |
| VERV | VERVE THERAPEUTICS INC | 0.72 | 575,817 | 8,026,890 | NEW | ||
| VNDA | VANDA PHARMACEUTICALS INC | 0.11 | 278,985 | 1,177,320 | UNCHANGED | 0.00 | |
| VYNE | VYNE THERAPEUTICS INC PIPE | 0.09 | 445,434 | 1,037,860 | NEW |