Latest DAFNA Capital Management LLC Stock Portfolio
DAFNA Capital Management LLC Performance:
2024 Q4: -8.51%YTD: -0.94%2023: 5.58%
Performance for 2024 Q4 is -8.51%, and YTD is -0.94%, and 2023 is 5.58%.
About DAFNA Capital Management LLC and 13F Hedge Fund Stock Holdings
DAFNA Capital Management LLC is a hedge fund based in LOS ANGELES, CA. On 30-Mar-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $542.7 Millions. In it's latest 13F Holdings report, DAFNA Capital Management LLC reported an equity portfolio of $393.4 Millions as of 31 Dec, 2024.
The top stock holdings of DAFNA Capital Management LLC are BIL, STXS, RVMD. The fund has invested 9.1% of it's portfolio in SPDR S&P BIOTECH ETF and 7.9% of portfolio in STEREOTAXIS INC.
The fund managers got completely rid off NYXOAH S A, VERASTEM INC (VSTM) and ADAPTIMMUNE THERAPEUTICS PLC (ADAP) stocks. They significantly reduced their stock positions in ACELYRIN INC, AQUESTIVE THERAPEUTICS INC (AQST) and CENTESSA PHARMACEUTICALS PLC (CNTA). DAFNA Capital Management LLC opened new stock positions in TELA BIO INC (TELA), BICARA THERAPEUTICS INC and ALIGN TECHNOLOGY INC (ALGN). The fund showed a lot of confidence in some stocks as they added substantially to NEUROGENE INC, FOGHORN THERAPEUTICS INC (FHTX) and IMMUNOVANT INC (IMVT).
The top stock holdings of DAFNA Capital Management LLC are BIL, STXS, RVMD. The fund has invested 9.1% of it's portfolio in SPDR S&P BIOTECH ETF and 7.9% of portfolio in STEREOTAXIS INC.
The fund managers got completely rid off NYXOAH S A, VERASTEM INC (VSTM) and ADAPTIMMUNE THERAPEUTICS PLC (ADAP) stocks. They significantly reduced their stock positions in ACELYRIN INC, AQUESTIVE THERAPEUTICS INC (AQST) and CENTESSA PHARMACEUTICALS PLC (CNTA). DAFNA Capital Management LLC opened new stock positions in TELA BIO INC (TELA), BICARA THERAPEUTICS INC and ALIGN TECHNOLOGY INC (ALGN). The fund showed a lot of confidence in some stocks as they added substantially to NEUROGENE INC, FOGHORN THERAPEUTICS INC (FHTX) and IMMUNOVANT INC (IMVT).
DAFNA Capital Management LLC Annual Return Estimates Vs S&P 500
Our best estimate is that DAFNA Capital Management LLC made a return of -8.51% in the last quarter. In trailing 12 months, it's portfolio return was -0.94%.
New Buys
| Ticker | $ Bought |
|---|---|
| tela bio inc | 4,351,910 |
| bicara therapeutics inc | 1,837,810 |
| align technology inc | 1,146,800 |
| taysha gene therapies inc | 903,925 |
| palvella therapeutics inc | 857,424 |
| vir biotechnology inc | 734,000 |
New stocks bought by DAFNA Capital Management LLC
Additions
| Ticker | % Inc. |
|---|---|
| neurogene inc | 562 |
| foghorn therapeutics inc | 395 |
| immunovant inc | 107 |
| lineage cell therapeutics in | 85.93 |
| keros therapeutics inc | 76.69 |
| proqr therapeutics n v | 73.1 |
| immatics nv | 68.97 |
| lexeo therapeutics inc | 56.87 |
Additions to existing portfolio by DAFNA Capital Management LLC
Reductions
| Ticker | % Reduced |
|---|---|
| acelyrin inc | -85.41 |
| aquestive therapeutics inc | -78.46 |
| centessa pharmaceuticals plc | -60.57 |
| viking therapeutics inc | -48.64 |
| perspective therapeutics inc | -43.48 |
| ars pharmaceuticals inc | -40.13 |
| 2seventy bio inc | -31.87 |
| larimar therapeutics inc | -24.85 |
DAFNA Capital Management LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| adaptimmune therapeutics plc | -324,147 |
| neuronetics inc | -238,362 |
| karyopharm therapeutics inc | -159,923 |
| verastem inc | -381,823 |
| nyxoah s a | -1,032,430 |
| grail inc | -671,488 |
| alto neuroscience inc | -306,432 |
| tourmaline bio inc | -491,318 |
DAFNA Capital Management LLC got rid off the above stocks
Sector Distribution
DAFNA Capital Management LLC has about 74.7% of it's holdings in Healthcare sector.
| Sector | % |
|---|---|
| Healthcare | 74.7 |
| Others | 25 |
Market Cap. Distribution
DAFNA Capital Management LLC has about 5% of it's portfolio invested in the large-cap and mega-cap stocks.
| Category | % |
|---|---|
| MID-CAP | 30.6 |
| SMALL-CAP | 26 |
| UNALLOCATED | 25.5 |
| MICRO-CAP | 12.7 |
| LARGE-CAP | 5 |
Stocks belong to which Index?
About 51.6% of the stocks held by DAFNA Capital Management LLC either belong to S&P 500 or RUSSELL 2000 index.
| Index | % |
|---|---|
| RUSSELL 2000 | 49.2 |
| Others | 48.3 |
| S&P 500 | 2.4 |
DAFNA Capital Management LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of DAFNA Capital Management LLC
DAFNA Capital Management LLC has 81 stocks in it's portfolio. About 52.5% of the portfolio is in top 10 stocks. KROS proved to be the most loss making stock for the portfolio. STXS was the most profitable stock for DAFNA Capital Management LLC last quarter.
Last Reported on: 14 Feb, 2025| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ACET | adicet bio inc | 0.15 | 600,000 | 577,200 | unchanged | 0.00 | ||
| ADAP | adaptimmune therapeutics plc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ADCT | adc therapeutics sa | 0.11 | 224,081 | 445,921 | added | 9.8 | ||
| ALEC | alector inc | 0.44 | 912,928 | 1,725,430 | unchanged | 0.00 | ||
| ALGN | align technology inc | 0.29 | 5,500 | 1,146,800 | new | |||
| ALKS | alkermes plc | 0.88 | 120,700 | 3,471,330 | unchanged | 0.00 | ||
| ALLO | allogene therapeutics inc | 0.67 | 1,240,120 | 2,641,450 | added | 18.09 | ||
| APRE | aprea therapeutics inc | 0.12 | 137,174 | 451,302 | unchanged | 0.00 | ||
| AQST | aquestive therapeutics inc | 0.12 | 127,000 | 452,120 | reduced | -78.46 | ||
| ARAY | accuray inc | 0.62 | 1,222,360 | 2,420,270 | unchanged | 0.00 | ||
| ATRC | atricure inc | 4.98 | 641,673 | 19,609,500 | unchanged | 0.00 | ||
| ATXS | astria therapeutics inc | 0.68 | 299,775 | 2,679,990 | added | 17.95 | ||
| AUTL | autolus therapeutics plc | 0.35 | 586,667 | 1,378,670 | added | 20.55 | ||
| AXGN | axogen inc | 3.55 | 846,882 | 13,956,600 | reduced | -9.51 | ||
| BCRX | biocryst pharmaceuticals inc | 1.27 | 667,000 | 5,015,840 | unchanged | 0.00 | ||
| BCYC | bicycle therapeutics plc | 0.43 | 120,799 | 1,691,190 | reduced | -1.15 | ||
| BDTX | black diamond therapeutics i | 0.08 | 140,000 | 299,600 | added | 12.00 | ||
| BIL | spdr s&p biotech etf | 9.10 | 397,505 | 35,799,300 | reduced | -1.00 | ||
| BPMC | blueprint medicines corp | 3.32 | 149,763 | 13,062,300 | added | 23.00 | ||
| CMPS | compass pathways plc | 0.23 | 243,210 | 919,334 | unchanged | 0.00 | ||