Latest Redmile Group, LLC Stock Portfolio
Redmile Group, LLC Performance:
2025 Q4: 33.34%YTD: 39.74%2024: -12.04%
Performance for 2025 Q4 is 33.34%, and YTD is 39.74%, and 2024 is -12.04%.
About Redmile Group, LLC and 13F Hedge Fund Stock Holdings
On 2026-02-17, the fund reported it's updated stock portfolio. In the 13F Holdings report, Redmile Group, LLC reported an equity portfolio of $1.4 Billions as of 31 Dec, 2025.
The top stock holdings of Redmile Group, LLC are SRRK, KRYS, NRIX. The fund has invested 16.9% of it's portfolio in SCHOLAR ROCK HLDG CORP and 12.3% of portfolio in KRYSTAL BIOTECH INC.
The fund managers got completely rid off AKERO THERAPEUTICS INC (AKRO), 89BIO INC (ETNB) and KEROS THERAPEUTICS INC (KROS) stocks. They significantly reduced their stock positions in LIVANOVA PLC (LIVN), ZYMEWORKS INC (ZYME) and COGENT BIOSCIENCES INC (COGT). Redmile Group, LLC opened new stock positions in DBV TECHNOLOGIES S A (DBVT), XENON PHARMACEUTICALS INC (XENE) and ORIC PHARMACEUTICALS INC (ORIC). The fund showed a lot of confidence in some stocks as they added substantially to NURIX THERAPEUTICS INC (NRIX), REPLIMUNE GROUP INC (REPL) and RAPT THERAPEUTICS INC (RAPT).
The top stock holdings of Redmile Group, LLC are SRRK, KRYS, NRIX. The fund has invested 16.9% of it's portfolio in SCHOLAR ROCK HLDG CORP and 12.3% of portfolio in KRYSTAL BIOTECH INC.
The fund managers got completely rid off AKERO THERAPEUTICS INC (AKRO), 89BIO INC (ETNB) and KEROS THERAPEUTICS INC (KROS) stocks. They significantly reduced their stock positions in LIVANOVA PLC (LIVN), ZYMEWORKS INC (ZYME) and COGENT BIOSCIENCES INC (COGT). Redmile Group, LLC opened new stock positions in DBV TECHNOLOGIES S A (DBVT), XENON PHARMACEUTICALS INC (XENE) and ORIC PHARMACEUTICALS INC (ORIC). The fund showed a lot of confidence in some stocks as they added substantially to NURIX THERAPEUTICS INC (NRIX), REPLIMUNE GROUP INC (REPL) and RAPT THERAPEUTICS INC (RAPT).
Redmile Group, LLC Annual Return Estimates Vs S&P 500
Our best estimate is that Redmile Group, LLC made a return of 33.34% in the last quarter. In trailing 12 months, it's portfolio return was 39.74%.
- Performance
- S&P 500
New Buys
| Ticker | $ Bought |
|---|---|
| dbv technologies s a | 10,540,400 |
| xenon pharmaceuticals inc | 6,000,590 |
| oric pharmaceuticals inc | 3,665,540 |
New stocks bought by Redmile Group, LLC
Additions
| Ticker | % Inc. |
|---|---|
| nurix therapeutics inc | 120 |
| replimune group inc | 105 |
| rapt therapeutics inc | 60.32 |
| annexon inc | 59.52 |
| scholar rock hldg corp | 33.72 |
| invivyd inc | 17.32 |
| immunome inc | 13.84 |
| neurogene inc | 12.36 |
Additions to existing portfolio by Redmile Group, LLC
Reductions
| Ticker | % Reduced |
|---|---|
| livanova plc | -87.26 |
| zymeworks inc | -86.73 |
| cogent biosciences inc | -34.91 |
| celldex therapeutics inc new | -13.36 |
| establishment labs hldgs inc | -12.91 |
| beam therapeutics inc | -7.33 |
| regenxbio inc | -6.92 |
| stoke therapeutics inc | -3.39 |
Redmile Group, LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| lava therapeutics nv | -3,236,020 |
| 89bio inc | -21,655,100 |
| ventyx biosciences inc | -3,338,230 |
| amicus therapeutics inc | -6,124,160 |
| akero therapeutics inc | -35,506,400 |
| keros therapeutics inc | -8,740,640 |
| xeris biopharma holdings inc | -3,671,950 |
| boundless bio inc | -301,913 |
Redmile Group, LLC got rid off the above stocks
Sector Distribution
Redmile Group, LLC has about 90.5% of it's holdings in Healthcare sector.
- Healthcare
- Others
| Sector | % |
|---|---|
| Healthcare | 90.5 |
| Others | 9 |
Market Cap. Distribution
Redmile Group, LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.
- MID-CAP
- SMALL-CAP
- UNALLOCATED
- MICRO-CAP
| Category | % |
|---|---|
| MID-CAP | 48.9 |
| SMALL-CAP | 38.4 |
| UNALLOCATED | 9 |
| MICRO-CAP | 3.1 |
Stocks belong to which Index?
About 75.9% of the stocks held by Redmile Group, LLC either belong to S&P 500 or RUSSELL 2000 index.
- RUSSELL 2000
- Others
| Index | % |
|---|---|
| RUSSELL 2000 | 75.9 |
| Others | 24.1 |
Redmile Group, LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Redmile Group, LLC
Redmile Group, LLC has 34 stocks in it's portfolio. About 77.8% of the portfolio is in top 10 stocks. ADCT proved to be the most loss making stock for the portfolio. NRIX was the most profitable stock for Redmile Group, LLC last quarter.
Last Reported on: 17 Feb, 2026| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ABSI | absci corporation | 2.12 | 8,253,320 | 28,804,100 | unchanged | 0.00 | ||
| ADCT | adc therapeutics sa | 4.07 | 15,666,700 | 55,303,600 | unchanged | 0.00 | ||
| ADGI | invivyd inc | 0.49 | 2,681,160 | 6,622,460 | added | 17.32 | ||
| AKRO | akero therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ALXO | alx oncology hldgs inc | 0.27 | 3,264,720 | 3,689,130 | reduced | -2.05 | ||
| ANNX | annexon inc | 3.72 | 10,050,600 | 50,454,200 | added | 59.52 | ||
| ATRA | atara biotherapeutics inc | 0.59 | 441,701 | 7,990,370 | unchanged | 0.00 | ||
| BEAM | beam therapeutics inc | 2.62 | 1,285,860 | 35,644,000 | reduced | -7.33 | ||
| CLDX | celldex therapeutics inc new | 0.57 | 283,308 | 7,694,640 | reduced | -13.36 | ||
| COGT | cogent biosciences inc | 3.76 | 1,437,920 | 51,074,800 | reduced | -34.91 | ||
| DBVT | dbv technologies s a | 0.78 | 549,840 | 10,540,400 | new | |||
| ESTA | establishment labs hldgs inc | 0.60 | 112,664 | 8,210,950 | reduced | -12.91 | ||
| ETNB | 89bio inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| FATE | fate therapeutics inc | 0.93 | 12,872,900 | 12,649,000 | unchanged | 0.00 | ||
| FOLD | amicus therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| IDYA | ideaya biosciences inc | 1.89 | 742,017 | 25,651,500 | unchanged | 0.00 | ||
| IMNM | immunome inc | 9.05 | 5,718,380 | 122,831,000 | added | 13.84 | ||
| KROS | keros therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| KRYS | krystal biotech inc | 12.30 | 677,705 | 167,081,000 | added | 2.47 | ||
| LIVN | livanova plc | 0.54 | 118,054 | 7,263,860 | reduced | -87.26 | ||