Latest Logos Global Management LP Stock Portfolio
Logos Global Management LP Performance:
2025 Q3: 19.9%YTD: 1.45%2024: -5.91%
Performance for 2025 Q3 is 19.9%, and YTD is 1.45%, and 2024 is -5.91%.
About Logos Global Management LP and 13F Hedge Fund Stock Holdings
In it's latest 13F Holdings report, Logos Global Management LP reported an equity portfolio of $1.1 Billions as of 30 Sep, 2025.
The top stock holdings of Logos Global Management LP are RVMD, IDYA, AKRO. The fund has invested 7.3% of it's portfolio in REVOLUTION MEDICINES INC and 5.5% of portfolio in IDEAYA BIOSCIENCES INC.
The fund managers got completely rid off UNITED THERAPEUTICS CORP DEL (UTHR), NEUROCRINE BIOSCIENCES INC (NBIX) and MADRIGAL PHARMACEUTICALS INC (MDGL) stocks. They significantly reduced their stock positions in KEROS THERAPEUTICS INC (KROS), JAZZ PHARMACEUTICALS PLC (JAZZ) and BIOGEN INC (BIIB). Logos Global Management LP opened new stock positions in ABIVAX SA, VAXCYTE INC (PCVX) and PROTAGONIST THERAPEUTICS INC (PTGX). The fund showed a lot of confidence in some stocks as they added substantially to VERASTEM INC (VSTM), TREVI THERAPEUTICS INC (TRVI) and MAZE THERAPEUTICS INC.
The top stock holdings of Logos Global Management LP are RVMD, IDYA, AKRO. The fund has invested 7.3% of it's portfolio in REVOLUTION MEDICINES INC and 5.5% of portfolio in IDEAYA BIOSCIENCES INC.
The fund managers got completely rid off UNITED THERAPEUTICS CORP DEL (UTHR), NEUROCRINE BIOSCIENCES INC (NBIX) and MADRIGAL PHARMACEUTICALS INC (MDGL) stocks. They significantly reduced their stock positions in KEROS THERAPEUTICS INC (KROS), JAZZ PHARMACEUTICALS PLC (JAZZ) and BIOGEN INC (BIIB). Logos Global Management LP opened new stock positions in ABIVAX SA, VAXCYTE INC (PCVX) and PROTAGONIST THERAPEUTICS INC (PTGX). The fund showed a lot of confidence in some stocks as they added substantially to VERASTEM INC (VSTM), TREVI THERAPEUTICS INC (TRVI) and MAZE THERAPEUTICS INC.
Logos Global Management LP Annual Return Estimates Vs S&P 500
Our best estimate is that Logos Global Management LP made a return of 19.9% in the last quarter. In trailing 12 months, it's portfolio return was -5.14%.
New Buys
| Ticker | $ Bought |
|---|---|
| abivax sa | 35,233,500 |
| vaxcyte inc | 22,512,500 |
| protagonist therapeutics inc | 19,929,000 |
| amylyx pharmaceuticals inc | 19,705,500 |
| lb pharmaceuticals inc | 17,842,700 |
| uniqure nv | 17,511,000 |
| kymera therapeutics inc | 14,150,000 |
| arcellx inc | 13,546,500 |
New stocks bought by Logos Global Management LP
Additions
| Ticker | % Inc. |
|---|---|
| verastem inc | 305 |
| trevi therapeutics inc | 158 |
| maze therapeutics inc | 100 |
| cidara therapeutics inc | 97.37 |
| arvinas inc | 68.94 |
| rhythm pharmaceuticals inc | 53.85 |
| immunocore hldgs plc | 47.83 |
| ocular therapeutix inc | 47.73 |
Additions to existing portfolio by Logos Global Management LP
Reductions
| Ticker | % Reduced |
|---|---|
| keros therapeutics inc | -57.5 |
| jazz pharmaceuticals plc | -55.56 |
| biogen inc | -50.00 |
| praxis precision medicines i | -44.44 |
| avidity biosciences inc | -36.84 |
| disc medicine inc | -35.71 |
| ideaya biosciences inc | -32.74 |
| astria therapeutics inc | -28.57 |
Logos Global Management LP reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| annexon inc | -5,784,000 |
| xencor inc | -9,825,000 |
| biohaven ltd | -9,877,000 |
| celldex therapeutics inc new | -12,210,000 |
| bicara therapeutics inc | -3,716,000 |
| legend biotech corp | -8,872,500 |
| rapport therapeutics inc | -2,375,310 |
| moonlake immunotherapeutics | -9,440,000 |
Logos Global Management LP got rid off the above stocks
Sector Distribution
Logos Global Management LP has about 83% of it's holdings in Healthcare sector.
| Sector | % |
|---|---|
| Healthcare | 83 |
| Others | 17 |
Market Cap. Distribution
Logos Global Management LP has about 1.4% of it's portfolio invested in the large-cap and mega-cap stocks.
| Category | % |
|---|---|
| MID-CAP | 33.9 |
| SMALL-CAP | 28.4 |
| UNALLOCATED | 20.1 |
| MICRO-CAP | 14.7 |
| LARGE-CAP | 1.4 |
| NANO-CAP | 1.4 |
Stocks belong to which Index?
About 66.2% of the stocks held by Logos Global Management LP either belong to S&P 500 or RUSSELL 2000 index.
| Index | % |
|---|---|
| RUSSELL 2000 | 64.8 |
| Others | 33.9 |
| S&P 500 | 1.4 |
Logos Global Management LP Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Logos Global Management LP
Logos Global Management LP has 53 stocks in it's portfolio. About 41% of the portfolio is in top 10 stocks. AKRO proved to be the most loss making stock for the portfolio. OLMA was the most profitable stock for Logos Global Management LP last quarter.
Last Reported on: 14 Nov, 2025| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ACLX | arcellx inc | 1.21 | 165,000 | 13,546,500 | new | |||
| ACRS | aclaris therapeutics inc | 0.26 | 1,500,000 | 2,850,000 | reduced | -18.92 | ||
| AKRO | akero therapeutics inc | 5.11 | 1,200,000 | 56,976,000 | unchanged | 0.00 | ||
| AMLX | amylyx pharmaceuticals inc | 1.77 | 1,450,000 | 19,705,500 | new | |||
| ANNX | annexon inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ARVN | arvinas inc | 4.26 | 5,575,000 | 47,499,000 | added | 68.94 | ||
| ATXS | astria therapeutics inc | 0.33 | 500,000 | 3,640,000 | reduced | -28.57 | ||
| AVTE | jade biosciences inc | 0.48 | 625,000 | 5,393,750 | unchanged | 0.00 | ||
| BIIB | biogen inc | 1.26 | 100,000 | 14,008,000 | reduced | -50.00 | ||
| CDTX | cidara therapeutics inc | 3.22 | 375,000 | 35,910,000 | added | 97.37 | ||
| CLDX | celldex therapeutics inc new | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| CMPX | compass therapeutics inc | 0.64 | 2,050,000 | 7,175,000 | new | |||
| CNTA | centessa pharmaceuticals plc | 1.14 | 525,000 | 12,731,200 | new | |||
| COGT | cogent biosciences inc | 0.64 | 500,000 | 7,180,000 | new | |||
| DSGN | design therapeutics inc | 2.47 | 3,655,000 | 27,522,200 | reduced | -13.34 | ||
| DYN | dyne therapeutics inc | 2.72 | 2,400,000 | 30,360,000 | added | 26.32 | ||
| ERAS | erasca inc | 2.96 | 15,150,000 | 33,027,000 | added | 1.00 | ||
| ESPR | esperion therapeutics inc ne | 0.18 | 750,000 | 1,987,500 | new | |||
| IDYA | ideaya biosciences inc | 5.49 | 2,250,000 | 61,222,500 | reduced | -32.74 | ||
| IMCR | immunocore hldgs plc | 2.77 | 850,000 | 30,880,500 | added | 47.83 | ||