Latest 5AM Venture Management, LLC Stock Portfolio
5AM Venture Management, LLC Performance:
2024 Q4: -3.56%YTD: 4.19%2023: -15.69%
Performance for 2024 Q4 is -3.56%, and YTD is 4.19%, and 2023 is -15.69%.
About 5AM Venture Management, LLC and 13F Hedge Fund Stock Holdings
In it's latest 13F Holdings report, 5AM Venture Management, LLC reported an equity portfolio of $419.1 Millions as of 31 Dec, 2024.
The top stock holdings of 5AM Venture Management, LLC are TRDA, , SKYE. The fund has invested 18.2% of it's portfolio in ENTRADA THERAPEUTICS INC and 8.8% of portfolio in ENLIVEN THERAPEUTICS INC.
The fund managers got completely rid off COGENT BIOSCIENCES INC (COGT) stocks. They significantly reduced their stock positions in PRAXIS PRECISION MEDICINES I (PRAX), CENTESSA PHARMACEUTICALS PLC (CNTA) and VIKING THERAPEUTICS INC (VKTX). 5AM Venture Management, LLC opened new stock positions in CAMP4 THERAPEUTICS CORP, AKERO THERAPEUTICS INC (AKRO) and PROTARA THERAPEUTICS INC (TARA).
The top stock holdings of 5AM Venture Management, LLC are TRDA, , SKYE. The fund has invested 18.2% of it's portfolio in ENTRADA THERAPEUTICS INC and 8.8% of portfolio in ENLIVEN THERAPEUTICS INC.
The fund managers got completely rid off COGENT BIOSCIENCES INC (COGT) stocks. They significantly reduced their stock positions in PRAXIS PRECISION MEDICINES I (PRAX), CENTESSA PHARMACEUTICALS PLC (CNTA) and VIKING THERAPEUTICS INC (VKTX). 5AM Venture Management, LLC opened new stock positions in CAMP4 THERAPEUTICS CORP, AKERO THERAPEUTICS INC (AKRO) and PROTARA THERAPEUTICS INC (TARA).
5AM Venture Management, LLC Annual Return Estimates Vs S&P 500
Our best estimate is that 5AM Venture Management, LLC made a return of -3.56% in the last quarter. In trailing 12 months, it's portfolio return was 4.19%.
New Buys
| Ticker | $ Bought |
|---|---|
| camp4 therapeutics corp | 15,283,700 |
| akero therapeutics inc | 4,590,300 |
| protara therapeutics inc | 4,224,000 |
| alector inc | 1,882,140 |
New stocks bought by 5AM Venture Management, LLC
Additions
Reductions
| Ticker | % Reduced |
|---|---|
| praxis precision medicines i | -50.00 |
| centessa pharmaceuticals plc | -35.34 |
| viking therapeutics inc | -20.19 |
| dianthus therapeutics inc | -16.56 |
| tectonic therapeutic inc | -7.71 |
| enliven therapeutics inc | -6.99 |
5AM Venture Management, LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| cogent biosciences inc | -6,068,020 |
5AM Venture Management, LLC got rid off the above stocks
Sector Distribution
5AM Venture Management, LLC has about 53.7% of it's holdings in Healthcare sector.
| Sector | % |
|---|---|
| Healthcare | 53.7 |
| Others | 46.3 |
Market Cap. Distribution
5AM Venture Management, LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.
| Category | % |
|---|---|
| UNALLOCATED | 46.3 |
| SMALL-CAP | 38.9 |
| MID-CAP | 8.5 |
| MICRO-CAP | 5.3 |
Stocks belong to which Index?
About 41.6% of the stocks held by 5AM Venture Management, LLC either belong to S&P 500 or RUSSELL 2000 index.
| Index | % |
|---|---|
| Others | 58.4 |
| RUSSELL 2000 | 41.6 |
5AM Venture Management, LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of 5AM Venture Management, LLC
5AM Venture Management, LLC has 31 stocks in it's portfolio. About 66.4% of the portfolio is in top 10 stocks. TYRA proved to be the most loss making stock for the portfolio. TRDA was the most profitable stock for 5AM Venture Management, LLC last quarter.
Last Reported on: 14 Feb, 2025| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ADVM | adverum biotechnologies inc | 0.60 | 541,666 | 2,529,580 | unchanged | 0.00 | ||
| AKRO | akero therapeutics inc | 1.09 | 165,000 | 4,590,300 | new | |||
| ALEC | alector inc | 0.45 | 995,841 | 1,882,140 | new | |||
| ANAB | anaptysbio inc | 1.13 | 357,733 | 4,736,380 | unchanged | 0.00 | ||
| CDTX | cidara therapeutics inc | 0.36 | 56,725 | 1,524,770 | unchanged | 0.00 | ||
| CLDX | celldex therapeutics inc new | 3.00 | 497,270 | 12,566,000 | unchanged | 0.00 | ||
| CNTA | centessa pharmaceuticals plc | 3.32 | 830,945 | 13,918,300 | reduced | -35.34 | ||
| COGT | cogent biosciences inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ERAS | erasca inc | 3.24 | 5,405,400 | 13,567,600 | unchanged | 0.00 | ||
| EYPT | eyepoint pharmaceuticals inc | 1.87 | 1,050,000 | 7,822,500 | unchanged | 0.00 | ||
| MLTX | moonlake immunotherapeutics | 3.65 | 282,313 | 15,287,200 | unchanged | 0.00 | ||
| MRSN | mersana therapeutics inc | 0.44 | 1,305,000 | 1,866,150 | unchanged | 0.00 | ||
| PHVS | pharvaris n v | 3.65 | 797,600 | 15,290,000 | unchanged | 0.00 | ||
| PRAX | praxis precision medicines i | 3.12 | 170,000 | 13,083,200 | reduced | -50.00 | ||
| RLYB | rallybio corp | 0.83 | 3,630,720 | 3,485,500 | unchanged | 0.00 | ||
| SCPH | scpharmaceuticals inc | 1.01 | 1,200,650 | 4,250,290 | unchanged | 0.00 | ||
| SKYE | skye bioscience inc | 6.70 | 9,913,170 | 28,054,300 | unchanged | 0.00 | ||
| TARA | protara therapeutics inc | 1.01 | 800,000 | 4,224,000 | new | |||
| TRDA | entrada therapeutics inc | 18.19 | 4,408,380 | 76,220,900 | unchanged | 0.00 | ||
| TYRA | tyra biosciences inc | 3.12 | 939,298 | 13,056,200 | unchanged | 0.00 | ||