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Latest 5AM Venture Management, LLC Stock Portfolio

$446Million– No. of Holdings #26

5AM Venture Management, LLC Performance:
2024 Q1: 10.73%YTD: 10.73%2023: -17.19%

Performance for 2024 Q1 is 10.73%, and YTD is 10.73%, and 2023 is -17.19%.

About 5AM Venture Management, LLC and 13F Hedge Fund Stock Holdings

In it's latest 13F Holdings report, 5AM Venture Management, LLC reported an equity portfolio of $446.6 Millions as of 31 Mar, 2024.

The top stock holdings of 5AM Venture Management, LLC are , TRDA, . The fund has invested 15.1% of it's portfolio in ENLIVEN THERAPEUTICS INC and 14% of portfolio in ENTRADA THERAPEUTICS INC.

The fund managers got completely rid off DISC MEDICINE INC, MIRATI THERAPEUTICS INC (MRTX) and SPRUCE BIOSCIENCES INC (SPRB) stocks. They significantly reduced their stock positions in VIKING THERAPEUTICS INC (VKTX), ENLIVEN THERAPEUTICS INC and MOONLAKE IMMUNOTHERAPEUTICS (MLTX). 5AM Venture Management, LLC opened new stock positions in PRAXIS PRECISION MEDICINES I (PRAX), CENTESSA PHARMACEUTICALS PLC (CNTA) and SILENCE THERAPEUTICS PLC (SLN). The fund showed a lot of confidence in some stocks as they added substantially to TYRA BIOSCIENCES INC (TYRA), GH RESEARCH PLC (GHRS) and VIRIDIAN THERAPEUTICS INC (VRDN).
5AM Venture Management, LLC Equity Portfolio Value
Last Reported on: 15 May, 2024

5AM Venture Management, LLC Annual Return Estimates Vs S&P 500

Our best estimate is that 5AM Venture Management, LLC made a return of 10.73% in the last quarter. In trailing 12 months, it's portfolio return was 0.85%.

New Buys

Ticker$ Bought
praxis precision medicines i20,746,800
centessa pharmaceuticals plc14,068,500
silence therapeutics plc10,285,900
adverum biotechnologies inc7,659,160
q32 bio inc4,293,980

New stocks bought by 5AM Venture Management, LLC

Additions

Ticker% Inc.
tyra biosciences inc69.25
gh research plc41.61
viridian therapeutics inc25.57
merus n v5.23

Additions to existing portfolio by 5AM Venture Management, LLC

Reductions

Ticker% Reduced
viking therapeutics inc-59.39
enliven therapeutics inc-25.67
biohaven ltd-20.00
dianthus therapeutics inc-15.64
moonlake immunotherapeutics-6.71

5AM Venture Management, LLC reduced stake in above stock

Sold off

Ticker$ Sold
spruce biosciences inc-6,926,520
disc medicine inc-16,994,200
homology medicines inc-2,757,840
mirati therapeutics inc-11,309,400

5AM Venture Management, LLC got rid off the above stocks

Sector Distribution

5AM Venture Management, LLC has about 63.9% of it's holdings in Healthcare sector.

Sector%
Healthcare63.9
Others36.1

Market Cap. Distribution

5AM Venture Management, LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.

Category%
UNALLOCATED36.1
SMALL-CAP32.8
MID-CAP21.5
MICRO-CAP9.5

Stocks belong to which Index?

About 45.4% of the stocks held by 5AM Venture Management, LLC either belong to S&P 500 or RUSSELL 2000 index.

Index%
Others54.6
RUSSELL 200045.4
Top 5 Winners (%)%
VKTX
viking therapeutics inc
194.5 %
RNA
avidity biosciences inc
182.0 %
MRSN
mersana therapeutics inc
93.1 %
MRUS
merus n v
59.0 %
PRAX
praxis precision medicines i
39.9 %
Top 5 Winners ($)$
VKTX
viking therapeutics inc
21.2 M
RNA
avidity biosciences inc
11.0 M
MRUS
merus n v
9.2 M
PRAX
praxis precision medicines i
5.9 M
MRSN
mersana therapeutics inc
2.8 M
Top 5 Losers (%)%
RLYB
rallybio corp
-22.6 %
SCPH
scpharmaceuticals inc
-19.9 %
VRDN
viridian therapeutics inc
-17.3 %
MLTX
moonlake immunotherapeutics
-16.5 %
ADVM
adverum biotechnologies inc
-12.0 %
Top 5 Losers ($)$
TRDA
entrada therapeutics inc
-4.1 M
MLTX
moonlake immunotherapeutics
-3.0 M
VRDN
viridian therapeutics inc
-2.7 M
RLYB
rallybio corp
-2.0 M
SCPH
scpharmaceuticals inc
-1.5 M

5AM Venture Management, LLC Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of 5AM Venture Management, LLC

5AM Venture Management, LLC has 26 stocks in it's portfolio. About 68.5% of the portfolio is in top 10 stocks. TRDA proved to be the most loss making stock for the portfolio. VKTX was the most profitable stock for 5AM Venture Management, LLC last quarter.

Last Reported on: 15 May, 2024
TickerNamesorted ascending% PortfolioShares Held$ ValueType% ChangeOptions