Latest TCG Crossover Management, LLC Stock Portfolio
$4.16Billion | No. of Holdings #54
TCG Crossover Management, LLC Performance
2026 Q2+16.99%
YTD+26.00%
2025+130.69%
About TCG Crossover Management, LLC and 13F Hedge Fund Stock Holdings
On 2026-08-14, the fund reported it's updated stock portfolio. In the 13F Holdings report, TCG Crossover Management, LLC reported an equity portfolio of $4.2 Billions as of 30 Jun, 2026. <br><br> The top stock holdings of TCG Crossover Management, LLC are , TNGX, . The fund has invested 19.2% of it's portfolio in ABIVAX SA AMERICAN DEPOSITARY SHARES and 6.8% of portfolio in TANGO THERAPEUTICS INC. <br><br> The fund managers got completely rid off CENTESSA PHARMACEUTICALS PLC (CNTA), FULCRUM THERAPEUTICS INC (FULC) and LIQUIDIA TECHNOLOGIES INC (LQDA) stocks. They significantly reduced their stock positions in ARVINAS HOLDING CO LLC (ARVN), BIOHAVEN LTD and ALX ONCOLOGY HOLDINGS INC (ALXO). TCG Crossover Management, LLC opened new stock positions in ZAI LAB LTD-ADR (ZLAB), AURA BIOSCIENCES INC (AURA) and FIRST TRACKS BIOTHERAPEUTICS. The fund showed a lot of confidence in some stocks as they added substantially to LEONABIO INC (ATHA), AVALO THERAPEUTICS INC (AVTX) and MONOPAR THERAPEUTICS INC (MNPR).
TCG Crossover Management, LLC Equity Portfolio Value
Last Reported on: 14 Aug, 2026
$4.16Billion
as of Aug 14, 2026TCG Crossover Management, LLC Annual Return Estimates Vs S&P 500
Our best estimate is that TCG Crossover Management, LLC made a return of 16.99% in the last quarter. In trailing 12 months, it's portfolio return was 224.55%.
- Performance
- S&P 500
New Buys
| Ticker | $ Bought |
|---|---|
| zai lab ltd-adr | 116,615,000 |
| aura biosciences inc | 67,686,700 |
| first tracks biotherapeutics | 58,253,500 |
| editas medicine inc | 36,000,000 |
| pharvaris bv | 34,864,600 |
| inflarx n v | 32,480,000 |
| altimmune inc | 30,400,000 |
| aktis oncology inc | 22,450,100 |
New stocks bought by TCG Crossover Management, LLC
Additions
| Ticker | % Inc. |
|---|---|
| leonabio inc | 890 |
| avalo therapeutics inc | 308 |
| monopar therapeutics inc | 53.92 |
Additions to existing portfolio by TCG Crossover Management, LLC
Reductions
| Ticker | % Reduced |
|---|---|
| arvinas holding co llc | -70.38 |
| biohaven ltd | -61.57 |
| alx oncology holdings inc | -56.54 |
| entrada therapeutics inc | -53.65 |
| revolution medicines inc | -40.86 |
| lb pharmaceuticals inc | -21.32 |
| tango therapeutics inc | -13.77 |
| abivax sa american depositary shares | -7.3 |
TCG Crossover Management, LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| fulcrum therapeutics inc | -40,267,500 |
| centessa pharmaceuticals plc | -170,259,000 |
| vistagen therapeutics inc | -1,529,660 |
| urogen pharma ltd | -7,288,460 |
| liquidia technologies inc | -15,211,000 |
| upstream bio inc | -1,629,570 |
| structure therapeutics inc | -6,767,810 |
TCG Crossover Management, LLC got rid off the above stocks
Sector Distribution
TCG Crossover Management, LLC has about 58.3% of it's holdings in Healthcare sector.
- Healthcare
- Others
| Sector | % |
|---|---|
| Healthcare | 58.3 |
| Others | 41.7 |
Market Cap. Distribution
TCG Crossover Management, LLC has about 4.3% of it's portfolio invested in the large-cap and mega-cap stocks.
- UNALLOCATED
- MID-CAP
- SMALL-CAP
- LARGE-CAP
- MICRO-CAP
| Category | % |
|---|---|
| UNALLOCATED | 41.7 |
| MID-CAP | 33.6 |
| SMALL-CAP | 17.5 |
| LARGE-CAP | 4.3 |
| MICRO-CAP | 2.8 |
Stocks belong to which Index?
About 48.1% of the stocks held by TCG Crossover Management, LLC either belong to S&P 500 or RUSSELL 2000 index.
- Others
- RUSSELL 2000
| Index | % |
|---|---|
| Others | 51.9 |
| RUSSELL 2000 | 48.1 |
TCG Crossover Management, LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of TCG Crossover Management, LLC
TCG Crossover Management, LLC has 54 stocks in it's portfolio. About 57.4% of the portfolio is in top 10 stocks. ADCT proved to be the most loss making stock for the portfolio. was the most profitable stock for TCG Crossover Management, LLC last quarter.
$4.16BTotal Value
61.00Positions
14 Aug, 2026Last Reported
| Expand | Holdingsorted ascending | % Portfolio | Shares Held | $ Value | % Change |
|---|---|---|---|---|---|
 ADCT Adc Therapeutics SaAdc Therapeutics SaADCT | 0.29% | 11,390,200 | $12.19M 0.29% | 0%unchanged 0 percentunchanged | |
 Spyre Therapeutics Inc TCG Crossover Management, LLC's holding in Spyre Therapeutics Inc over time | 4.06% | 1,900,580 | $168.73M 4.06% | 0%unchanged 0 percentunchanged | |
 Alector Inc Alector IncALEC TCG Crossover Management, LLC's holding in Alector Inc over time | 0.48% | 10,000,000 | $20.10M 0.48% | 0%unchanged 0 percentunchanged | |
 Altimmune Inc TCG Crossover Management, LLC's holding in Altimmune Inc over time | 0.73% | 10,000,000 | $30.40M 0.73% | Newnew position | |
 Alx Oncology Holdings Inc TCG Crossover Management, LLC's holding in Alx Oncology Holdings Inc over time | 0.28% | 5,655,490 | $11.71M 0.28% | 56.54%decreased 56.54 percentreduced | |
 Amylyx Pharmaceuticals Inc TCG Crossover Management, LLC's holding in Amylyx Pharmaceuticals Inc over time | 2.69% | 6,243,810 | $112.14M 2.69% | 0%unchanged 0 percentunchanged | |
 Arvinas Holding Co Llc TCG Crossover Management, LLC's holding in Arvinas Holding Co Llc over time | 0.14% | 707,098 | $5.88M 0.14% | 70.38%decreased 70.38 percentreduced | |
 Leonabio Inc Leonabio IncATHA TCG Crossover Management, LLC's holding in Leonabio Inc over time | 0.1% | 464,398 | $4.27M 0.1% | 890%increased 890 percentadded | |
 Aura Biosciences Inc TCG Crossover Management, LLC's holding in Aura Biosciences Inc over time | 1.63% | 9,533,330 | $67.69M 1.63% | Newnew position | |
 Avalo Therapeutics Inc TCG Crossover Management, LLC's holding in Avalo Therapeutics Inc over time | 1.34% | 3,017,120 | $55.76M 1.34% | 308.61%increased 308.61 percentadded | |
 Biocryst Pharmaceuticals Inc TCG Crossover Management, LLC's holding in Biocryst Pharmaceuticals Inc over time | 2.65% | 11,021,000 | $110.21M 2.65% | 0%unchanged 0 percentunchanged | |
 Cullinan Therapeutics Inc TCG Crossover Management, LLC's holding in Cullinan Therapeutics Inc over time | 0.18% | 406,786 | $7.41M 0.18% | 0%unchanged 0 percentunchanged | |
 Centessa Pharmaceuticals Plc TCG Crossover Management, LLC's holding in Centessa Pharmaceuticals Plc over time | 0% | 0.00 | $0.00 0% | 100%decreased 100 percentsold off | |
 Context Therapeutics Inc TCG Crossover Management, LLC's holding in Context Therapeutics Inc over time | 0.04% | 2,682,700 | $1.49M 0.04% | 0%unchanged 0 percentunchanged | |
 Cogent Biosciences Inc TCG Crossover Management, LLC's holding in Cogent Biosciences Inc over time | 4.52% | 4,854,440 | $187.87M 4.52% | 1.87%decreased 1.87 percentreduced | |
 Dyne Therapeutics Inc TCG Crossover Management, LLC's holding in Dyne Therapeutics Inc over time | 2.46% | 4,615,140 | $102.50M 2.46% | 0%unchanged 0 percentunchanged | |
 Editas Medicine Inc TCG Crossover Management, LLC's holding in Editas Medicine Inc over time | 0.86% | 11,111,100 | $36.00M 0.86% | Newnew position | |
 Forte Biosciences Inc TCG Crossover Management, LLC's holding in Forte Biosciences Inc over time | 0.47% | 920,000 | $19.55M 0.47% | Newnew position | |
 Fulcrum Therapeutics Inc TCG Crossover Management, LLC's holding in Fulcrum Therapeutics Inc over time | 0% | 0.00 | $0.00 0% | 100%decreased 100 percentsold off | |
 Monte Rosa Therapeutics Inc TCG Crossover Management, LLC's holding in Monte Rosa Therapeutics Inc over time | 2.69% | 4,622,150 | $111.86M 2.69% | 0%unchanged 0 percentunchanged | |