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Date

Name

Buy/Sell

$ Value

# Shares

Avg. Price

Title

General Counsel and Secretary

Principal Accounting Officer

Chief Executive Officer

Chief Financial Officer

Chief Commercial Officer

Chief Medical Officer

President and CEO

Praxis Precision Medicines, Inc., a clinical-stage biopharmaceutical company, develops therapies for central nervous system disorders characterized by neuronal excitation-inhibition imbalance. It is developing ulixacaltamide, a small molecule inhibitor of T-type calcium channels that is in Phase IIb clinical trial for the treatment of essential tremor, as well as in Phase II clinical trial to treat Parkinson's disease; PRAX-562 for the treatment of pediatric patients with developmental and epileptic encephalopathies (DEE); and PRAX-628 to treat focal epilepsy. The company also develops PRAX-222 for the treatment of pediatric patients with early-onset SCN2A-DEE; PRAX-020 to treat KCNT1 related epilepsies; PRAX-080 for the treatment of PCDH19; and PRAX-090 and PRAX-100 for SYNGAP1 and SCN2A-LoF. It has a license agreement with RogCon Inc.; a research collaboration and license agreement with Ionis Pharmaceuticals, Inc.; a strategic collaboration and license agreement with UCB Biopharma SRL; and collaboration with The Florey Institute to develop three novel ASOs. Praxis Precision Medicines, Inc. was incorporated in 2015 and is based in Boston, Massachusetts.

Praxis Precision Medicines, Inc., a clinical-stage biopharmaceutical company, develops therapies for central nervous system disorders char...

Datesorted ascending	Name	Buy/Sell	$ Value	# Shares	Avg. Price	Title
2024-02-12	Premium	sold (taxes)	Premium	Premium	Premium	General Counsel and Secretary
2024-02-12	Premium	sold (taxes)	Premium	Premium	Premium	Principal Accounting Officer
2024-02-12	Premium	sold (taxes)	Premium	Premium	Premium	Chief Executive Officer
2024-01-07	Premium	sold (taxes)	Premium	Premium	Premium	Chief Financial Officer
2024-01-07	Premium	sold (taxes)	Premium	Premium	Premium	General Counsel and Secretary
2024-01-07	Premium	sold (taxes)	Premium	Premium	Premium	Principal Accounting Officer
2024-01-07	Premium	sold (taxes)	Premium	Premium	Premium	Chief Executive Officer
2023-10-05	Premium	bought	Premium	Premium	Premium	-
2023-06-27	Premium	bought	Premium	Premium	Premium	Chief Executive Officer
2023-05-12	Premium	acquired	Premium	Premium	Premium	General Counsel and Secretary
2023-05-12	Premium	acquired	Premium	Premium	Premium	Chief Financial Officer
2023-05-12	Premium	acquired	Premium	Premium	Premium	Chief Executive Officer
2023-03-24	Premium	bought	Premium	Premium	Premium	-
2023-03-24	Premium	bought	Premium	Premium	Premium	Chief Financial Officer
2023-03-24	Premium	bought	Premium	Premium	Premium	Chief Financial Officer
2023-03-23	Premium	bought	Premium	Premium	Premium	Chief Executive Officer
2023-03-23	Premium	bought	Premium	Premium	Premium	Chief Executive Officer
2023-02-12	Premium	sold (taxes)	Premium	Premium	Premium	Principal Accounting Officer
2023-02-12	Premium	sold (taxes)	Premium	Premium	Premium	General Counsel and Secretary
2023-02-12	Premium	sold (taxes)	Premium	Premium	Premium	Chief Commercial Officer
2023-01-07	Premium	sold (taxes)	Premium	Premium	Premium	Chief Financial Officer
2023-01-07	Premium	sold (taxes)	Premium	Premium	Premium	Chief Commercial Officer
2023-01-07	Premium	sold (taxes)	Premium	Premium	Premium	Principal Accounting Officer
2023-01-07	Premium	sold (taxes)	Premium	Premium	Premium	General Counsel and Secretary
2022-11-14	Premium	acquired	Premium	Premium	Premium	General Counsel and Secretary

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