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Latest GREAT POINT PARTNERS LLC Stock Portfolio

$435Million | No. of Holdings #39

GREAT POINT PARTNERS LLC Performance

2026 Q1+10.74%
YTD+10.74%
2025+43.33%

About GREAT POINT PARTNERS LLC and 13F Hedge Fund Stock Holdings

GREAT POINT PARTNERS LLC is a hedge fund based in Greenwich, CT. On 2026-05-15, the fund reported it's updated stock portfolio. In the 13F Holdings report, GREAT POINT PARTNERS LLC reported an equity portfolio of $435.1 Millions as of 31 Mar, 2026. <br><br> The top stock holdings of GREAT POINT PARTNERS LLC are , VOR, . The fund has invested 7.2% of it's portfolio in APOGEE THERAPEUTICS INC and 7.2% of portfolio in VOR BIOPHARMA INC. <br><br> The fund managers got completely rid off DISC MEDICINE INC, RAPT THERAPEUTICS INC (RAPT) and SOLENO THERAPEUTICS INC (SLNO) stocks. They significantly reduced their stock positions in CULLINAN THERAPEUTICS INC (CGEM), CONTEXT THERAPEUTICS INC (CNTX) and IMMUNOVANT INC (IMVT). GREAT POINT PARTNERS LLC opened new stock positions in SOL-GEL TECHNOLOGIES LTD (SLGL), ALUMIS INC and BRIGHT MINDS BIOSCIENCES INC (DRUG). The fund showed a lot of confidence in some stocks as they added substantially to NEKTAR THERAPEUTICS (NKTR), NEUROGENE INC and CLIMB BIO INC (ELYM).
GREAT POINT PARTNERS LLC Equity Portfolio Value
Last Reported on: 15 May, 2026
$435Million
  as of May 15, 2026

GREAT POINT PARTNERS LLC Annual Return Estimates Vs S&P 500

Our best estimate is that GREAT POINT PARTNERS LLC made a return of 10.74% in the last quarter. In trailing 12 months, it's portfolio return was 91.08%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
sol-gel technologies ltd21,735,000
alumis inc18,859,000
bright minds biosciences inc16,053,400
annexon inc13,850,000
zenas biopharma inc10,245,500
moonlake immunotherapeutics9,320,000
vera therapeutics inc8,019,770
lb pharmaceuticals inc7,398,000
New stocks bought by GREAT POINT PARTNERS LLC

Additions

Ticker% Inc.
nektar therapeutics50.17
neurogene inc42.86
climb bio inc36.2
vor biopharma inc27.73
silence therapeutics plc26.29
jade biosciences inc19.62
zura bio ltd10.48
contineum therapeutics inc0.02
Additions to existing portfolio by GREAT POINT PARTNERS LLC

Reductions

Ticker% Reduced
cullinan therapeutics inc-52.68
context therapeutics inc-52.21
immunovant inc-27.25
kalvista pharmaceuticals inc-1.55
GREAT POINT PARTNERS LLC reduced stake in above stock

Sold off

Ticker$ Sold
fulcrum therapeutics inc-9,048,000
sana biotechnology inc-2,849,000
rapt therapeutics inc-19,684,800
soleno therapeutics inc-18,520,000
dianthus therapeutics inc-14,423,500
ultragenyx pharmaceutical in-6,900,000
upstream bio inc-8,145,000
disc medicine inc-19,852,500
GREAT POINT PARTNERS LLC got rid off the above stocks

Sector Distribution

GREAT POINT PARTNERS LLC has about 54.9% of it's holdings in Healthcare sector.

  • Healthcare
  • Others
Sector%
Healthcare54.9
Others45.1

Market Cap. Distribution

GREAT POINT PARTNERS LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.

  • UNALLOCATED
  • SMALL-CAP
  • MICRO-CAP
  • MID-CAP
  • NANO-CAP
Category%
UNALLOCATED45.1
SMALL-CAP27.4
MICRO-CAP18.9
MID-CAP5.7
NANO-CAP2.9

Stocks belong to which Index?

About 32.7% of the stocks held by GREAT POINT PARTNERS LLC either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • RUSSELL 2000
Index%
Others67.3
RUSSELL 200032.7
Top 5 Winners (%)%
oruka therapeutics inc
61.8 %
CNTX
context therapeutics inc
57.8 %
ELYM
climb bio inc
56.4 %
NKTR
nektar therapeutics
52.3 %
evommune inc
34.3 %
Top 5 Winners ($)$
NKTR
nektar therapeutics
7.8 M
VOR
vor biopharma inc
7.4 M
CNTX
context therapeutics inc
4.0 M
oruka therapeutics inc
3.4 M
ELYM
climb bio inc
3.3 M
Top 5 Losers (%)%
AVTX
avalo therapeutics inc
-17.8 %
SLN
silence therapeutics plc
-12.1 %
AVTE
jade biosciences inc
-8.3 %
eupraxia pharmaceuticals inc
-4.1 %
IMVT
immunovant inc
-2.0 %
Top 5 Losers ($)$
AVTE
jade biosciences inc
-1.2 M
SLN
silence therapeutics plc
-0.7 M
AVTX
avalo therapeutics inc
-0.4 M
IMVT
immunovant inc
-0.4 M
eupraxia pharmaceuticals inc
-0.4 M

GREAT POINT PARTNERS LLC Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of GREAT POINT PARTNERS LLC

GREAT POINT PARTNERS LLC has 39 stocks in it's portfolio. About 50.3% of the portfolio is in top 10 stocks. AVTE proved to be the most loss making stock for the portfolio. NKTR was the most profitable stock for GREAT POINT PARTNERS LLC last quarter.

$408.27MTotal Value
47.00Positions
15 May, 2026Last Reported
Current holdings of Current Stock Holdings of GREAT POINT PARTNERS LLC, last reported on 15 May, 2026. Select a row with a linked ticker to view its historical trend.
ExpandHoldingsorted ascending% PortfolioShares Held$ Value% Change
DRUG
Bright Minds Biosciences Inc

Bright Minds Biosciences Inc

DRUG
GREAT POINT PARTNERS LLC's holding in Bright Minds Biosciences Inc over time
3.69%220,000
$16.05M
3.69%
new position
PHVS
Pharvaris N V

Pharvaris N V

PHVS
GREAT POINT PARTNERS LLC's holding in Pharvaris N V over time
0.54%82,800
$2.34M
0.54%
unchanged 0 percentunchanged