Latest GREAT POINT PARTNERS LLC Stock Portfolio

$529Million | No. of Holdings #37

GREAT POINT PARTNERS LLC Performance

2026 Q2+9.69%
YTD+21.47%
2025+43.33%

About GREAT POINT PARTNERS LLC and 13F Hedge Fund Stock Holdings

GREAT POINT PARTNERS LLC is a hedge fund based in Greenwich, CT. On 2026-08-14, the fund reported it's updated stock portfolio. In the 13F Holdings report, GREAT POINT PARTNERS LLC reported an equity portfolio of $529.1 Millions as of 30 Jun, 2026. <br><br> The top stock holdings of GREAT POINT PARTNERS LLC are VOR, , VERA. The fund has invested 5.9% of it's portfolio in VOR BIOPHARMA INC and 5.2% of portfolio in ABIVAX SA. <br><br> The fund managers got completely rid off APOGEE THERAPEUTICS INC, KALVISTA PHARMACEUTICALS INC (KALV) and IMMUNOVANT INC (IMVT) stocks. They significantly reduced their stock positions in PROMIS NEUROSCIENCES INC (PMN), AMYLYX PHARMACEUTICALS INC (AMLX) and SILENCE THERAPEUTICS PLC (SLN). GREAT POINT PARTNERS LLC opened new stock positions in ABIVAX SA, INFLARX NV (IFRX) and ALTIMMUNE INC (ALT). The fund showed a lot of confidence in some stocks as they added substantially to OPUS GENETICS INC (OCUP), IMMIX BIOPHARMA INC (IMMX) and VERA THERAPEUTICS INC (VERA).
GREAT POINT PARTNERS LLC Equity Portfolio Value
Last Reported on: 14 Aug, 2026
$529Million
  as of Aug 14, 2026

GREAT POINT PARTNERS LLC Annual Return Estimates Vs S&P 500

Our best estimate is that GREAT POINT PARTNERS LLC made a return of 9.69% in the last quarter. In trailing 12 months, it's portfolio return was 91.3%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
abivax sa27,226,900
definium therapeutics inc19,992,000
sagimet biosciences inc15,691,400
inflarx nv6,824,290
jatt ii acquisition corp5,680,000
altimmune inc5,293,340
amanat acquisition corp5,080,000
scynexis inc3,843,270

New stocks bought by GREAT POINT PARTNERS LLC

Additions

Ticker% Inc.
opus genetics inc507
immix biopharma inc265
vera therapeutics inc201
moonlake immunotherapeutics71.16
annexon inc40.00
contineum therapeutics inc15.16
lb pharmaceuticals inc5.74

Additions to existing portfolio by GREAT POINT PARTNERS LLC

Reductions

Ticker% Reduced
promis neurosciences inc-76.8
amylyx pharmaceuticals inc-60.00
silence therapeutics plc-55.9
bright minds biosciences inc-50.18
nektar therapeutics-44.7
palisade bio inc-32.91
neurogene inc-29.56
climb bio inc-25.04

GREAT POINT PARTNERS LLC reduced stake in above stock

Sold off

Ticker$ Sold
context therapeutics inc-5,864,860
compass therapeutics inc-7,141,500
jade biosciences inc-13,550,700
scynexis inc-6,926,580
unicycive therapeutics inc-5,241,350
kalvista pharmaceuticals inc-13,587,800
immunovant inc-13,553,300
zenas biopharma inc-10,245,500

GREAT POINT PARTNERS LLC got rid off the above stocks

Sector Distribution

GREAT POINT PARTNERS LLC has about 54.7% of it's holdings in Others sector.

  • Others
  • Healthcare
Sector%
Others54.7
Healthcare45.3

Market Cap. Distribution

GREAT POINT PARTNERS LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.

  • UNALLOCATED
  • SMALL-CAP
  • MID-CAP
  • MICRO-CAP
Category%
UNALLOCATED54.7
SMALL-CAP25.3
MID-CAP12.5
MICRO-CAP6.6

Stocks belong to which Index?

About 24.3% of the stocks held by GREAT POINT PARTNERS LLC either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • RUSSELL 2000
Index%
Others75.7
RUSSELL 200024.3
Top 5 Winners (%)%
oruka therapeutics inc
94.0 %
ELYM
climb bio inc
79.0 %
SLN
silence therapeutics plc
78.1 %
RZLT
rezolute inc
70.5 %
neurogene inc
47.7 %
Top 5 Winners ($)$
oruka therapeutics inc
8.5 M
ELYM
climb bio inc
7.2 M
alumis inc
5.2 M
AMLX
amylyx pharmaceuticals inc
5.0 M
neurogene inc
4.8 M
Top 5 Losers (%)%
evommune inc
-42.2 %
eupraxia pharmaceuticals inc
-8.7 %
SLGL
sol-gel technologies ltd
-6.4 %
OCUP
opus genetics inc
-5.9 %
DRUG
bright minds biosciences inc
-2.8 %
Top 5 Losers ($)$
evommune inc
-3.2 M
SLGL
sol-gel technologies ltd
-1.4 M
eupraxia pharmaceuticals inc
-0.8 M
NKTR
nektar therapeutics
-0.5 M
OCUP
opus genetics inc
-0.5 M

GREAT POINT PARTNERS LLC Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of GREAT POINT PARTNERS LLC

GREAT POINT PARTNERS LLC has 37 stocks in it's portfolio. About 43% of the portfolio is in top 10 stocks. proved to be the most loss making stock for the portfolio. was the most profitable stock for GREAT POINT PARTNERS LLC last quarter.

$424.45MTotal Value
50.00Positions
14 Aug, 2026Last Reported
Current holdings of Current Stock Holdings of GREAT POINT PARTNERS LLC, last reported on 14 Aug, 2026. Select a row with a linked ticker to view its historical trend.
ExpandHoldingsorted ascending% PortfolioShares Held$ Value% Change
DBVT
Dbv Technologies S A

Dbv Technologies S A

DBVT
GREAT POINT PARTNERS LLC's holding in Dbv Technologies S A over time
0.49%156,906
$2.57M
0.49%
new position
DRUG
Bright Minds Biosciences Inc

Bright Minds Biosciences Inc

DRUG
GREAT POINT PARTNERS LLC's holding in Bright Minds Biosciences Inc over time
1.45%109,603
$7.69M
1.45%
decreased 50.18 percentreduced
IFRX
Inflarx Nv

Inflarx Nv

IFRX
GREAT POINT PARTNERS LLC's holding in Inflarx Nv over time
1.29%3,046,560
$6.82M
1.29%
new position