Latest Ikarian Capital, LLC Stock Portfolio
Ikarian Capital, LLC Performance:
2025 Q2: 0.81%YTD: -11.35%2024: 6.28%
Performance for 2025 Q2 is 0.81%, and YTD is -11.35%, and 2024 is 6.28%.
About Ikarian Capital, LLC and 13F Hedge Fund Stock Holdings
Ikarian Capital, LLC is a hedge fund based in DALLAS, TX. On 18-Sep-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $375.1 Millions. In it's latest 13F Holdings report, Ikarian Capital, LLC reported an equity portfolio of $520.6 Millions as of 30 Jun, 2025.
The top stock holdings of Ikarian Capital, LLC are CDTX, ALNY, INSM. The fund has invested 4.3% of it's portfolio in CIDARA THERAPEUTICS INC and 3.5% of portfolio in ALNYLAM PHARMACEUTICALS INC.
The fund managers got completely rid off BLUEPRINT MEDICINES CORP (BPMC), EDGEWISE THERAPEUTICS INC (EWTX) and ENLIVEN THERAPEUTICS INC stocks. They significantly reduced their stock positions in LEXICON PHARMACEUTICALS INC (LXRX), VIGIL NEUROSCIENCE INC (VIGL) and AVALO THERAPEUTICS INC (AVTX). Ikarian Capital, LLC opened new stock positions in APOGEE THERAPEUTICS INC, COGENT BIOSCIENCES INC (COGT) and JAZZ PHARMACEUTICALS PLC (JAZZ). The fund showed a lot of confidence in some stocks as they added substantially to GERON CORP (GERN), ARVINAS INC (ARVN) and DELCATH SYS INC (DCTH).
The top stock holdings of Ikarian Capital, LLC are CDTX, ALNY, INSM. The fund has invested 4.3% of it's portfolio in CIDARA THERAPEUTICS INC and 3.5% of portfolio in ALNYLAM PHARMACEUTICALS INC.
The fund managers got completely rid off BLUEPRINT MEDICINES CORP (BPMC), EDGEWISE THERAPEUTICS INC (EWTX) and ENLIVEN THERAPEUTICS INC stocks. They significantly reduced their stock positions in LEXICON PHARMACEUTICALS INC (LXRX), VIGIL NEUROSCIENCE INC (VIGL) and AVALO THERAPEUTICS INC (AVTX). Ikarian Capital, LLC opened new stock positions in APOGEE THERAPEUTICS INC, COGENT BIOSCIENCES INC (COGT) and JAZZ PHARMACEUTICALS PLC (JAZZ). The fund showed a lot of confidence in some stocks as they added substantially to GERON CORP (GERN), ARVINAS INC (ARVN) and DELCATH SYS INC (DCTH).
Ikarian Capital, LLC Annual Return Estimates Vs S&P 500
Our best estimate is that Ikarian Capital, LLC made a return of 0.81% in the last quarter. In trailing 12 months, it's portfolio return was -8.16%.
New Buys
| Ticker | $ Bought |
|---|---|
| apogee therapeutics inc | 10,077,800 |
| cogent biosciences inc | 7,435,090 |
| jazz pharmaceuticals plc | 4,244,800 |
| cg oncology inc | 4,030,000 |
| newamsterdam pharma company | 3,745,150 |
| biogen inc | 2,702,200 |
| kalvista pharmaceuticals inc | 2,244,360 |
| proqr thrapeutics n v | 1,770,860 |
New stocks bought by Ikarian Capital, LLC
Additions
| Ticker | % Inc. |
|---|---|
| geron corp | 966 |
| arvinas inc | 269 |
| delcath sys inc | 221 |
| sarepta therapeutics inc | 165 |
| fulcrum therapeutics inc | 114 |
| viking therapeutics inc | 100 |
| insmed inc | 93.1 |
| praxis precision medicines i | 90.34 |
Additions to existing portfolio by Ikarian Capital, LLC
Reductions
| Ticker | % Reduced |
|---|---|
| lexicon pharmaceuticals inc | -87.55 |
| vigil neuroscience inc | -87.46 |
| avalo therapeutics inc | -82.35 |
| terns pharmaceuticals inc | -81.04 |
| scholar rock hldg corp | -79.86 |
| cybin inc | -64.63 |
| oruka therapeutics inc | -60.81 |
| tarsus pharmaceuticals inc | -59.48 |
Ikarian Capital, LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| allakos inc | -266,736 |
| elevation oncology inc | -178,792 |
| pyxis oncology inc | -600,927 |
| trevi therapeutics inc | -3,616,750 |
| abeona therapeutics inc | -2,539,850 |
| channel therapeutics corpora | -626,004 |
| verve therapeutics inc | -1,637,860 |
| enliven therapeutics inc | -5,698,110 |
Ikarian Capital, LLC got rid off the above stocks
Sector Distribution
Ikarian Capital, LLC has about 83.4% of it's holdings in Healthcare sector.
| Sector | % |
|---|---|
| Healthcare | 83.4 |
| Others | 16.6 |
Market Cap. Distribution
Ikarian Capital, LLC has about 15% of it's portfolio invested in the large-cap and mega-cap stocks.
| Category | % |
|---|---|
| SMALL-CAP | 27 |
| MID-CAP | 22.8 |
| UNALLOCATED | 17.8 |
| LARGE-CAP | 15 |
| MICRO-CAP | 13.7 |
| NANO-CAP | 3.7 |
Stocks belong to which Index?
About 45.4% of the stocks held by Ikarian Capital, LLC either belong to S&P 500 or RUSSELL 2000 index.
| Index | % |
|---|---|
| Others | 53.7 |
| RUSSELL 2000 | 45.4 |
Ikarian Capital, LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Ikarian Capital, LLC
Ikarian Capital, LLC has 103 stocks in it's portfolio. About 26.1% of the portfolio is in top 10 stocks. SRPT proved to be the most loss making stock for the portfolio. CDTX was the most profitable stock for Ikarian Capital, LLC last quarter.
Last Reported on: 14 Aug, 2025| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ABEO | abeona therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ABOS | acumen pharmaceuticals inc | 0.06 | 265,769 | 308,292 | unchanged | 0.00 | ||
| ACRS | aclaris therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| AEMD | aethlon med inc | 0.04 | 153,659 | 184,391 | new | |||
| AEMD | aethlon med inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| AIRS | airsculpt technologies inc | 0.02 | 17,951 | 86,703 | new | |||
| AKRO | akero therapeutics inc | 2.26 | 220,000 | 11,739,200 | reduced | -10.2 | ||
| ALEC | alector inc | 0.24 | 900,000 | 1,260,000 | reduced | -5.26 | ||
| ALLK | allakos inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ALNY | alnylam pharmaceuticals inc | 3.54 | 56,594 | 18,454,700 | added | 79.13 | ||
| ANAB | anaptysbio inc | 0.07 | 15,662 | 347,696 | new | |||
| ANEB | anebulo pharmaceuticals inc | 0.04 | 157,720 | 227,117 | unchanged | 0.00 | ||
| APLS | apellis pharmaceuticals inc | 0.25 | 75,000 | 1,298,250 | unchanged | 0.00 | ||
| ARCT | arcturus therapeutics hldgs | 0.44 | 175,000 | 2,276,750 | unchanged | 0.00 | ||
| ARVN | arvinas inc | 1.20 | 850,000 | 6,256,000 | added | 269 | ||
| AVTX | avalo therapeutics inc | 0.03 | 35,300 | 176,147 | reduced | -82.35 | ||
| BIIB | biogen inc | 0.52 | 21,516 | 2,702,200 | new | |||
| BPMC | blueprint medicines corp | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| CDTX | cidara therapeutics inc | 4.35 | 464,488 | 22,625,200 | added | 86.59 | ||
| COGT | cogent biosciences inc | 1.43 | 1,035,530 | 7,435,090 | new | |||