Latest Sectoral Asset Management Inc Stock Portfolio

Sectoral Asset Management Inc Performance:

2025 Q4: 14.28%YTD: 32.3%2024: 1.58%

Performance for 2025 Q4 is 14.28%, and YTD is 32.3%, and 2024 is 1.58%.

About Sectoral Asset Management Inc and 13F Hedge Fund Stock Holdings

On 2026-02-09, the fund reported it's updated stock portfolio. In the 13F Holdings report, SECTORAL ASSET MANAGEMENT INC reported an equity portfolio of $124.8 Millions as of 31 Dec, 2025.

The top stock holdings of SECTORAL ASSET MANAGEMENT INC are , , LLY. The fund has invested 8.1% of it's portfolio in EVOMMUNE INC and 7.3% of portfolio in CONTINEUM THERAPEUTICS.

The fund managers got completely rid off ANAPTYSBIO INC (ANAB), BICARA THERAPEUTICS and SOLID BIOSCIENCES (SLDB) stocks. They significantly reduced their stock positions in ORIC PHARMACEUTICALS (ORIC), VENTYX BIOSCIENCES (VTYX) and STRUCTURE THERAPEUTICS. SECTORAL ASSET MANAGEMENT INC opened new stock positions in EVOMMUNE INC, COGENT BIOSCIENCES INC (COGT) and INSPIRE MED SYS INC (INSP). The fund showed a lot of confidence in some stocks as they added substantially to UNITED THERAPEUTICS (UTHR), AXSOME THERAPEUTICS (AXSM) and STRYKER CORP (SYK).

Sectoral Asset Management Inc Annual Return Estimates Vs S&P 500

Our best estimate is that SECTORAL ASSET MANAGEMENT INC made a return of 14.28% in the last quarter. In trailing 12 months, it's portfolio return was 32.3%.

Performance
S&P 500

New Buys

Ticker	$ Bought
evommune inc	10,083,800
cogent biosciences inc	1,160,970
lenz therapeutics inc	680,000
inspire med sys inc	664,056
carlsmed inc	589,095
nektar therapeutics	570,146

New stocks bought by Sectoral Asset Management Inc

Additions

Ticker	% Inc.
united therapeutics	125
axsome therapeutics	70.59
stryker corp	52.33
dexcom inc	38.65
abbott labs	36.63
omada health inc	32.73
johnson & johnson	32.68
merck & co inc	30.49

Additions to existing portfolio by Sectoral Asset Management Inc

Reductions

Ticker	% Reduced
oric pharmaceuticals	-93.16
ventyx biosciences	-91.24
structure therapeutics	-89.24
immatics nv	-88.76
kura oncology	-86.33
arcus biosciences	-84.53
tectonic therapeutics	-78.08
pfizer inc	-64.81

Sectoral Asset Management Inc reduced stake in above stock

Sold off

Ticker	$ Sold
solid biosciences	-3,905,930
bicara therapeutics	-4,207,960
mbx biosciences inc	-3,410,720
anaptysbio inc	-5,955,130
instil bio inc	-2,882,250
zenas biopharma	-3,374,960
palvella therapeutic	-3,079,020
spdr series trust	-3,406,800

Sectoral Asset Management Inc got rid off the above stocks

Sector Distribution

SECTORAL ASSET MANAGEMENT INC has about 65.8% of it's holdings in Healthcare sector.

Sector	%
Healthcare	65.8
Others	33.9

Market Cap. Distribution

SECTORAL ASSET MANAGEMENT INC has about 49.9% of it's portfolio invested in the large-cap and mega-cap stocks.

Category	%
UNALLOCATED	33.9
LARGE-CAP	29.3
MEGA-CAP	20.6
MID-CAP	7.1
SMALL-CAP	7.1
MICRO-CAP	2

Stocks belong to which Index?

About 59.2% of the stocks held by SECTORAL ASSET MANAGEMENT INC either belong to S&P 500 or RUSSELL 2000 index.

Index	%
S&P 500	44.9
Others	40.7
RUSSELL 2000	14.3

Top 5 Winners (%)		%
VTYX	ventyx biosciences	103.5 %
	structure therapeutics	82.2 %
VERA	vera therapeutics	63.3 %
FOLD	amicus therapeutics	55.0 %
RCUS	arcus biosciences	43.4 %

Top 5 Winners ($)		$
	structure therapeutics	5.1 M
VTYX	ventyx biosciences	3.6 M
LLY	eli lilly & co	2.6 M
RCUS	arcus biosciences	2.2 M
	shoulder innovations	0.8 M

Top 5 Losers (%)		%
QURE	uniqure n.v.	-58.9 %
	omada health inc	-26.0 %
	tempus ai inc	-25.2 %
ORIC	oric pharmaceuticals	-17.0 %
SMMT	summit therapeutics	-14.9 %

Top 5 Losers ($)		$
QURE	uniqure n.v.	-1.1 M
ORIC	oric pharmaceuticals	-0.7 M
	contineum therapeutics	-0.3 M
SMMT	summit therapeutics	-0.2 M
UNH	unitedhealth grp inc	-0.2 M

Sectoral Asset Management Inc Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Sectoral Asset Management Inc

SECTORAL ASSET MANAGEMENT INC has 74 stocks in it's portfolio. About 46.1% of the portfolio is in top 10 stocks. QURE proved to be the most loss making stock for the portfolio. was the most profitable stock for SECTORAL ASSET MANAGEMENT INC last quarter.

Last Reported on: 09 Feb, 2026

Ticker	Namesorted ascending	% Portfolio	Shares Held	$ Value	Type	% Change
ABBV	abbvie inc	3.08	16,800	3,838,630	added	13.51

ABT	abbott labs	2.36	23,498	2,944,060	added	36.63

ALHC	alignment healthcare	0.50	31,500	622,125	reduced	-42.2

ALNY	alnylam pharmaceuticals inc	0.95	2,990	1,188,970	reduced	-8.65

AMGN	amgen inc	3.43	13,070	4,277,940	added	26.4

ANAB	anaptysbio inc	0.00	0.00	0.00	sold off	-100

AXSM	axsome therapeutics	0.26	1,740	317,794	added	70.59

BBIO	bridgebio pharma	0.69	11,170	854,393	reduced	-18.17

BGNE	beone medicines ltd	0.65	2,665	809,654	reduced	-62.99

BIIB	biogen inc	0.30	2,155	379,259	reduced	-9.26

BIL	spdr series trust	0.00	0.00	0.00	sold off	-100

BMRN	biomarin pharmaceutical inc	0.52	10,880	646,599	reduced	-56.53

BMY	bristol myers squibb	0.00	0.00	0.00	sold off	-100

BSX	boston scientific	2.11	27,626	2,634,140	added	24.86

CI	the cigna group	0.00	0.00	0.00	sold off	-100

COGT	cogent biosciences inc	0.93	32,685	1,160,970	new

CYTK	cytokinetics inc	0.30	5,893	374,441	reduced	-42.36

DHR	danaher corp	1.94	10,575	2,420,830	unchanged	0.00

DXCM	dexcom inc	1.53	28,700	1,904,820	added	38.65

EW	edwards lifescience	1.18	17,250	1,470,560	added	15.00