Latest Nantahala Capital Management, LLC Stock Portfolio
Nantahala Capital Management, LLC Performance:
2025 Q3: 18.68%YTD: 24.14%2024: 26.63%
Performance for 2025 Q3 is 18.68%, and YTD is 24.14%, and 2024 is 26.63%.
About Nantahala Capital Management, LLC and 13F Hedge Fund Stock Holdings
Nantahala Capital Management, LLC is a hedge fund based in NEW CANAAN, CT. On 14-Jun-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $2.5 Billions. In it's latest 13F Holdings report, Nantahala Capital Management, LLC reported an equity portfolio of $2.9 Billions as of 30 Sep, 2025.
The top stock holdings of Nantahala Capital Management, LLC are ESTA, HGV, TBBK. The fund has invested 2.8% of it's portfolio in ESTABLISHMENT LABS HLDGS INC and 2.4% of portfolio in HILTON GRAND VACATIONS INC.
The fund managers got completely rid off THIRD HARMONIC BIO INC (THRD), GOGO INC (GOGO) and REZOLUTE INC (RZLT) stocks. They significantly reduced their stock positions in AMYLYX PHARMACEUTICALS INC (AMLX), ABIVAX SA and COMPASS PATHWAYS PLC (CMPS). Nantahala Capital Management, LLC opened new stock positions in FRACTYL HEALTH INC, GLOBUS MED INC (GMED) and GERON CORP (GERN). The fund showed a lot of confidence in some stocks as they added substantially to COLUMBUS MCKINNON CORP N Y (CMCO), STRUCTURE THERAPEUTICS INC and TALPHERA INC (ACRX).
The top stock holdings of Nantahala Capital Management, LLC are ESTA, HGV, TBBK. The fund has invested 2.8% of it's portfolio in ESTABLISHMENT LABS HLDGS INC and 2.4% of portfolio in HILTON GRAND VACATIONS INC.
The fund managers got completely rid off THIRD HARMONIC BIO INC (THRD), GOGO INC (GOGO) and REZOLUTE INC (RZLT) stocks. They significantly reduced their stock positions in AMYLYX PHARMACEUTICALS INC (AMLX), ABIVAX SA and COMPASS PATHWAYS PLC (CMPS). Nantahala Capital Management, LLC opened new stock positions in FRACTYL HEALTH INC, GLOBUS MED INC (GMED) and GERON CORP (GERN). The fund showed a lot of confidence in some stocks as they added substantially to COLUMBUS MCKINNON CORP N Y (CMCO), STRUCTURE THERAPEUTICS INC and TALPHERA INC (ACRX).
Nantahala Capital Management, LLC Annual Return Estimates Vs S&P 500
Our best estimate is that Nantahala Capital Management, LLC made a return of 18.68% in the last quarter. In trailing 12 months, it's portfolio return was 31.27%.
New Buys
| Ticker | $ Bought |
|---|---|
| fractyl health inc | 19,297,700 |
| globus med inc | 17,181,000 |
| dianthus therapeutics inc | 14,756,200 |
| geron corp | 12,364,200 |
| lb pharmaceuticals inc | 10,658,200 |
| mimedx group inc | 10,236,600 |
| dariohealth corp | 9,772,090 |
| cytokinetics inc | 8,244,000 |
New stocks bought by Nantahala Capital Management, LLC
Additions
| Ticker | % Inc. |
|---|---|
| columbus mckinnon corp n y | 120 |
| structure therapeutics inc | 118 |
| talphera inc | 75.28 |
| destination xl group inc | 74.83 |
| 1 800 flowers com inc | 68.4 |
| inspiremd inc | 45.66 |
| evolus inc | 36.42 |
| ehealth inc | 34.31 |
Additions to existing portfolio by Nantahala Capital Management, LLC
Reductions
| Ticker | % Reduced |
|---|---|
| amylyx pharmaceuticals inc | -68.11 |
| abivax sa | -62.4 |
| compass pathways plc | -58.61 |
| verastem inc | -56.24 |
| mineralys therapeutics inc | -55.16 |
| uniqure nv | -50.9 |
| kodiak sciences inc | -50.77 |
| industrial logistics pptys t | -47.75 |
Nantahala Capital Management, LLC reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| third harmonic bio inc | -15,957,100 |
| theratechnologies inc | -5,717,250 |
| rezolute inc | -10,219,600 |
| cargo therapeutics inc | -4,532,000 |
| gogo inc | -15,332,000 |
| syndax pharmaceuticals inc | -7,065,920 |
| olaplex hldgs inc | -910,000 |
| iteos therapeutics inc | -5,948,760 |
Nantahala Capital Management, LLC got rid off the above stocks
Sector Distribution
Nantahala Capital Management, LLC has about 55.9% of it's holdings in Healthcare sector.
| Sector | % |
|---|---|
| Healthcare | 55.9 |
| Others | 14.2 |
| Consumer Cyclical | 12.9 |
| Financial Services | 4.4 |
| Real Estate | 3.1 |
| Communication Services | 3 |
| Industrials | 2.7 |
| Technology | 2.2 |
| Consumer Defensive | 1.1 |
Market Cap. Distribution
Nantahala Capital Management, LLC has about 0% of it's portfolio invested in the large-cap and mega-cap stocks.
| Category | % |
|---|---|
| SMALL-CAP | 46.4 |
| MICRO-CAP | 19.9 |
| UNALLOCATED | 14.6 |
| MID-CAP | 14.5 |
| NANO-CAP | 4.6 |
Stocks belong to which Index?
About 44.9% of the stocks held by Nantahala Capital Management, LLC either belong to S&P 500 or RUSSELL 2000 index.
| Index | % |
|---|---|
| Others | 55 |
| RUSSELL 2000 | 44.9 |
Nantahala Capital Management, LLC Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Nantahala Capital Management, LLC
Nantahala Capital Management, LLC has 131 stocks in it's portfolio. About 19% of the portfolio is in top 10 stocks. CRMT proved to be the most loss making stock for the portfolio. QURE was the most profitable stock for Nantahala Capital Management, LLC last quarter.
Last Reported on: 14 Nov, 2025| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ABEO | abeona therapeutics inc | 0.84 | 4,564,660 | 24,101,400 | added | 4.46 | ||
| ACHV | achieve life sciences inc | 0.07 | 648,885 | 2,043,990 | reduced | -27.81 | ||
| ACRX | talphera inc | 0.11 | 3,492,520 | 3,119,520 | added | 75.28 | ||
| ACU | acme utd corp | 0.03 | 20,427 | 841,184 | unchanged | 0.00 | ||
| ADCT | adc therapeutics sa | 0.32 | 2,266,290 | 9,065,160 | unchanged | 0.00 | ||
| AGIO | agios pharmaceuticals inc | 0.14 | 100,000 | 4,014,000 | new | |||
| AKBA | akebia therapeutics inc | 0.19 | 2,000,000 | 5,460,000 | unchanged | 0.00 | ||
| ALTG | alta equipment group inc | 0.23 | 934,774 | 6,767,760 | reduced | -10.36 | ||
| AMLX | amylyx pharmaceuticals inc | 0.44 | 935,684 | 12,715,900 | reduced | -68.11 | ||
| AMRX | amneal pharmaceuticals inc | 1.47 | 4,224,560 | 42,287,900 | reduced | -3.27 | ||
| ANEB | anebulo pharmaceuticals inc | 0.26 | 3,036,320 | 7,590,810 | unchanged | 0.00 | ||
| ANIK | anika therapeutics inc | 0.01 | 20,961 | 197,033 | new | |||
| APRE | aprea therapeutics inc | 0.01 | 205,760 | 303,496 | unchanged | 0.00 | ||
| APYX | apyx medical corporation | 0.25 | 3,338,050 | 7,143,420 | unchanged | 0.00 | ||
| AQST | aquestive therapeutics inc | 0.12 | 600,000 | 3,354,000 | new | |||
| ASPS | altisource portfolio solutio | 0.06 | 2,477,310 | 1,734,120 | unchanged | 0.00 | ||
| ASPS | altisource portfolio solutio | 0.05 | 2,477,310 | 1,436,840 | unchanged | 0.00 | ||
| ASPS | altisource portfolio solutio | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ASRT | assertio holdings inc | 0.27 | 8,810,070 | 7,759,910 | unchanged | 0.00 | ||
| ATXS | astria therapeutics inc | 0.27 | 1,069,530 | 7,786,180 | unchanged | 0.00 | ||