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Latest Rock Springs Capital Management LP Stock Portfolio

Rock Springs Capital Management LP Performance:
2025 Q1: -3.91%YTD: -3.91%2024: -2.82%

Performance for 2025 Q1 is -3.91%, and YTD is -3.91%, and 2024 is -2.82%.

About Rock Springs Capital Management LP and 13F Hedge Fund Stock Holdings

Rock Springs Capital Management LP is a hedge fund based in BALTIMORE, MD. On 31-Mar-2023, the fund reported that it had an AUM (Regulated Assets under Management) of $5.7 Billions. In it's latest 13F Holdings report, Rock Springs Capital Management LP reported an equity portfolio of $1.7 Billions as of 31 Mar, 2025.

The top stock holdings of Rock Springs Capital Management LP are , LLY, BPMC. The fund has invested 6% of it's portfolio in ARGENX SE and 5.4% of portfolio in ELI LILLY & CO.

The fund managers got completely rid off FRESHPET INC (FRPT), INSULET CORP (PODD) and LIFESTANCE HEALTH GROUP INC (LFST) stocks. They significantly reduced their stock positions in BIOCRYST PHARMACEUTICALS INC (BCRX), WEST PHARMACEUTICAL SVSC INC (WST) and NEUROCRINE BIOSCIENCES INC (NBIX). Rock Springs Capital Management LP opened new stock positions in DANAHER CORPORATION (DHR), MINERALYS THERAPEUTICS INC and REGENERON PHARMACEUTICALS (REGN). The fund showed a lot of confidence in some stocks as they added substantially to TARSUS PHARMACEUTICALS INC (TARS), LENZ THERAPEUTICS INC and 89BIO INC (ETNB).

Rock Springs Capital Management LP Annual Return Estimates Vs S&P 500

Our best estimate is that Rock Springs Capital Management LP made a return of -3.91% in the last quarter. In trailing 12 months, it's portfolio return was -7.85%.

New Buys

Ticker$ Bought
danaher corporation12,054,000
mineralys therapeutics inc5,094,510
kestra med technologies ltd3,613,400
regeneron pharmaceuticals1,775,840
amylyx pharmaceuticals inc1,215,030
sionna therapeutics inc1,040,030

New stocks bought by Rock Springs Capital Management LP

Additions to existing portfolio by Rock Springs Capital Management LP

Reductions

Ticker% Reduced
biocryst pharmaceuticals inc-91.71
west pharmaceutical svsc inc-64.3
neurocrine biosciences inc-61.28
edwards lifesciences corp-53.21
intuitive surgical inc-52.78
nevro corp-51.43
sarepta therapeutics inc-48.2
alnylam pharmaceuticals inc-44.09

Rock Springs Capital Management LP reduced stake in above stock

Sold off

Ticker$ Sold
xilio therapeutics inc-2,868,110
lifestance health group inc-18,793,500
acumen pharmaceuticals inc-3,162,940
leap therapeutics inc-3,641,320
allakos inc-1,331,500
autolus therapeutics plc-2,427,520
neumora therapeutics inc.-10,124,100
nevro corp-489,102

Rock Springs Capital Management LP got rid off the above stocks

Sector Distribution

Rock Springs Capital Management LP has about 87% of it's holdings in Healthcare sector.

Sector%
Healthcare87
Others13

Market Cap. Distribution

Rock Springs Capital Management LP has about 28% of it's portfolio invested in the large-cap and mega-cap stocks.

Category%
MID-CAP39.5
LARGE-CAP19.6
SMALL-CAP16.2
UNALLOCATED14.5
MEGA-CAP8.4
MICRO-CAP1.8

Stocks belong to which Index?

About 61.4% of the stocks held by Rock Springs Capital Management LP either belong to S&P 500 or RUSSELL 2000 index.

Index%
RUSSELL 200044.3
Others38.7
S&P 50017.1
Top 5 Winners (%)%
AGL
agilon health inc
125.0 %
SLNO
soleno therapeutics inc
59.0 %
NVRO
nevro corp
55.3 %
AKRO
akero therapeutics inc
49.3 %
CMPX
compass therapeutics inc
38.3 %
Top 5 Winners ($)$
AGL
agilon health inc
17.7 M
AKRO
akero therapeutics inc
13.0 M
ZLAB
zai lab ltd
12.0 M
LLY
eli lilly & co
7.8 M
TVTX
travere therapeutics inc
7.4 M
Top 5 Losers (%)%
PLRX
pliant therapeutics inc
-86.5 %
JSPR
jasper therapeutics inc
-77.4 %
MRSN
mersana therapeutics inc
-74.3 %
INZY
inozyme pharma inc
-65.8 %
ADAP
adaptimmune therapeutics plc
-63.4 %
Top 5 Losers ($)$
WST
west pharmaceutical svsc inc
-16.7 M
NBIX
neurocrine biosciences inc
-15.1 M
SRPT
sarepta therapeutics inc
-11.4 M
KYMR
kymera therapeutics inc
-11.0 M
RVMD
revolution medicines inc
-10.5 M

Rock Springs Capital Management LP Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Rock Springs Capital Management LP

Rock Springs Capital Management LP has 95 stocks in it's portfolio. About 36.6% of the portfolio is in top 10 stocks. WST proved to be the most loss making stock for the portfolio. AGL was the most profitable stock for Rock Springs Capital Management LP last quarter.

Last Reported on: 15 May, 2025
TickerNamesorted ascending% PortfolioShares Held$ ValueType% ChangeOptions