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Latest Sofinnova Investments, Inc. Stock Portfolio

$1.93Billion | No. of Holdings #53

Sofinnova Investments, Inc. Performance

2026 Q2+14.58%
YTD+13.84%
2025+43.58%

About Sofinnova Investments, Inc. and 13F Hedge Fund Stock Holdings

On 2026-08-14, the fund reported it's updated stock portfolio. In the 13F Holdings report, Sofinnova Investments, Inc. reported an equity portfolio of $1.9 Billions as of 30 Jun, 2026. <br><br> The top stock holdings of Sofinnova Investments, Inc. are NTRA, VERA, GMAB. The fund has invested 21.8% of it's portfolio in NATERA INC and 6.2% of portfolio in VERA THERAPEUTICS INC. <br><br> The fund managers got completely rid off ASTRAZENECA PLC, BIOGEN INC (BIIB) and CELCUITY INC (CELC) stocks. They significantly reduced their stock positions in PRAXIS PRECISION MEDICINES I (PRAX), TYRA BIOSCIENCES INC (TYRA) and ALCON AG (ALC). Sofinnova Investments, Inc. opened new stock positions in SEAPORT THERAPEUTICS INC, GILEAD SCIENCES INC (GILD) and NURIX THERAPEUTICS INC (NRIX). The fund showed a lot of confidence in some stocks as they added substantially to GENMAB A/S (GMAB), TENAX THERAPEUTICS INC (TENX) and ONKURE THERAPEUTICS INC.
Sofinnova Investments, Inc. Equity Portfolio Value
Last Reported on: 14 Aug, 2026
$1.93Billion
  as of Aug 14, 2026

Sofinnova Investments, Inc. Annual Return Estimates Vs S&P 500

Our best estimate is that Sofinnova Investments, Inc. made a return of 14.58% in the last quarter. In trailing 12 months, it's portfolio return was 69.07%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
seaport therapeutics inc77,429,000
gilead sciences inc43,347,300
nurix therapeutics inc12,714,600
design therapeutics inc12,518,500
first tracks biotherapeutics11,371,800
abbott laboratories11,160,800
sionna therapeutics inc6,353,560
absci corporation3,910,470
New stocks bought by Sofinnova Investments, Inc.

Additions

Ticker% Inc.
genmab a/s437
tenax therapeutics inc378
onkure therapeutics inc127
veradermics inc103
disc medicine inc86.72
anaptysbio inc32.54
supernus pharmaceuticals8.59
pharvaris n v7.7
Additions to existing portfolio by Sofinnova Investments, Inc.

Reductions

Ticker% Reduced
praxis precision medicines i-89.89
tyra biosciences inc-84.18
alcon ag-64.95
bristol-myers squibb co-55.9
insmed inc-54.23
biomarin pharmaceutical inc-54.15
united therapeutics corp del-52.22
cogent biosciences inc-51.02
Sofinnova Investments, Inc. reduced stake in above stock

Sold off

Ticker$ Sold
oric pharmaceuticals inc-8,610,250
roivant sciences ltd-13,240,500
astrazeneca plc-89,938,400
bridgebio pharma inc-30,385,900
tango therapeutics inc-8,265,100
dexcom inc-24,716,600
celcuity inc-41,795,200
xenon pharmaceuticals inc-17,748,300
Sofinnova Investments, Inc. got rid off the above stocks

Sector Distribution

Sofinnova Investments, Inc. has about 70% of it's holdings in Healthcare sector.

  • Healthcare
  • Others
Sector%
Healthcare70
Others30

Market Cap. Distribution

Sofinnova Investments, Inc. has about 39.1% of it's portfolio invested in the large-cap and mega-cap stocks.

  • LARGE-CAP
  • UNALLOCATED
  • MID-CAP
  • SMALL-CAP
Category%
LARGE-CAP39.1
UNALLOCATED30
MID-CAP27.5
SMALL-CAP3.4

Stocks belong to which Index?

About 32% of the stocks held by Sofinnova Investments, Inc. either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • RUSSELL 2000
  • S&P 500
Index%
Others68
RUSSELL 200026.4
S&P 5005.6
Top 5 Winners (%)%
definium therapeutics inc
129.8 %
ANAB
anaptysbio inc
65.8 %
AVTE
jade biosciences inc
58.1 %
veradermics inc
56.9 %
arrivent biopharma inc
50.6 %
Top 5 Winners ($)$
NTRA
natera inc
110.8 M
RARE
ultragenyx pharmaceutical in
30.3 M
JAZZ
jazz pharmaceuticals plc
25.0 M
arrivent biopharma inc
19.8 M
rapport therapeutics inc
19.8 M
Top 5 Losers (%)%
NXTC
nextcure inc
-85.0 %
INSM
insmed inc
-25.4 %
WVE
wave life sciences ltd
-19.9 %
SUPN
supernus pharmaceuticals
-9.7 %
TYRA
tyra biosciences inc
-9.6 %
Top 5 Losers ($)$
INSM
insmed inc
-14.4 M
UTHR
united therapeutics corp del
-6.1 M
SUPN
supernus pharmaceuticals
-5.2 M
BMY
bristol-myers squibb co
-4.3 M
ALC
alcon ag
-4.1 M

Sofinnova Investments, Inc. Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Sofinnova Investments, Inc.

Sofinnova Investments, Inc. has 53 stocks in it's portfolio. About 57.9% of the portfolio is in top 10 stocks. INSM proved to be the most loss making stock for the portfolio. NTRA was the most profitable stock for Sofinnova Investments, Inc. last quarter.

$1.87BTotal Value
71.00Positions
14 Aug, 2026Last Reported
Current holdings of Current Stock Holdings of Sofinnova Investments, Inc., last reported on 14 Aug, 2026. Select a row with a linked ticker to view its historical trend.
ExpandHoldingsorted ascending% PortfolioShares Held$ Value% Change
ALC
Alcon Ag

Alcon Ag

ALC
Sofinnova Investments, Inc.'s holding in Alcon Ag over time
0.89%255,824
$17.17M
0.89%
decreased 64.95 percentreduced