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Latest Avidity Partners Management LP Stock Portfolio

$624Million | No. of Holdings #45

Avidity Partners Management LP Performance

2026 Q2+10.31%
YTD+47.37%
2025+19.16%

About Avidity Partners Management LP and 13F Hedge Fund Stock Holdings

Avidity Partners Management LP is a hedge fund based in Dallas, TX. On 2026-08-14, the fund reported it's updated stock portfolio. In the 13F Holdings report, Avidity Partners Management LP reported an equity portfolio of $624.4 Millions as of 30 Jun, 2026. <br><br> The top stock holdings of Avidity Partners Management LP are , , . The fund has invested 32.9% of it's portfolio in DIANTHUS THERAPEUTICS INC and 15.9% of portfolio in CG ONCOLOGY INC. <br><br> The fund managers got completely rid off IMMUNIC INC (IMUX), HUMANA INC (HUM) and SCYNEXIS INC (SCYX) stocks. They significantly reduced their stock positions in PELOTON INTERACTIVE INC (PTON), TEVA PHARMACEUTICAL INDS LTD (TEVA) and VIR BIOTECHNOLOGY INC (VIR). Avidity Partners Management LP opened new stock positions in MOBIA MED INC, IMMUNIC INC (IMUX) and SENSEONICS HLDGS INC (SENS). The fund showed a lot of confidence in some stocks as they added substantially to INSULET CORP (PODD) and STRUCTURE THERAPEUTICS INC.
Avidity Partners Management LP Equity Portfolio Value
Last Reported on: 14 Aug, 2026
$624Million
  as of Aug 14, 2026

Avidity Partners Management LP Annual Return Estimates Vs S&P 500

Our best estimate is that Avidity Partners Management LP made a return of 10.31% in the last quarter. In trailing 12 months, it's portfolio return was 90.22%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
mobia med inc10,697,000
immunic inc10,297,000
senseonics hldgs inc9,088,000
nuvectis pharma inc3,678,000
alamar biosciences inc2,979,900
avalyn pharmaceuticals inc1,975,200
kailera therapeutics inc1,762,400
scynexis inc1,059,040
New stocks bought by Avidity Partners Management LP

Additions

Ticker% Inc.
insulet corp140
structure therapeutics inc25.64
tempus ai inc16.67
cg oncology inc8.53
Additions to existing portfolio by Avidity Partners Management LP

Reductions

Ticker% Reduced
peloton interactive inc-75.00
teva pharmaceutical inds ltd-69.24
vir biotechnology inc-66.91
corvus pharmaceuticals inc-65.22
medtronic plc-65.00
phathom pharmaceuticals inc-59.9
context therapeutics inc-50.00
encompass health corp-50.00
Avidity Partners Management LP reduced stake in above stock

Sold off

Ticker$ Sold
immunic inc-13,881,200
scynexis inc-3,844,620
anteris technologies global-1,755,000
arbutus biopharma corp-1,087,500
hims & hers health inc-2,915,500
moonlake immunotherapeutics-1,751,000
kenvue inc ord-1,724,000
centene corp-2,291,800
Avidity Partners Management LP got rid off the above stocks

Sector Distribution

Avidity Partners Management LP has about 78.2% of it's holdings in Others sector.

  • Others
  • Healthcare
Sector%
Others78.2
Healthcare21.7

Market Cap. Distribution

Avidity Partners Management LP has about 5.9% of it's portfolio invested in the large-cap and mega-cap stocks.

  • UNALLOCATED
  • SMALL-CAP
  • LARGE-CAP
  • MICRO-CAP
  • MID-CAP
Category%
UNALLOCATED78.2
SMALL-CAP8.9
LARGE-CAP5.9
MICRO-CAP5
MID-CAP1.8

Stocks belong to which Index?

About 13.7% of the stocks held by Avidity Partners Management LP either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • RUSSELL 2000
  • S&P 500
Index%
Others86.3
RUSSELL 20009.7
S&P 5004
Top 5 Winners (%)%
aktis oncology inc
57.6 %
oruka therapeutics inc
46.5 %
KPTI
karyopharm therapeutics inc
40.7 %
CRL
charles riv labs intl inc
35.8 %
TRVI
trevi therapeutics inc
33.9 %
Top 5 Winners ($)$
oruka therapeutics inc
41.6 M
dianthus therapeutics inc
36.7 M
aktis oncology inc
9.9 M
enliven therapeutics inc
7.1 M
AVTE
jade biosciences inc
6.7 M
Top 5 Losers (%)%
CNTX
context therapeutics inc
-58.3 %
BSX
boston scientific corp
-24.2 %
perspective therapeutics inc
-11.8 %
bridgebio oncology therapeut
-9.2 %
PODD
insulet corp
-8.5 %
Top 5 Losers ($)$
CNTX
context therapeutics inc
-14.5 M
perspective therapeutics inc
-5.7 M
BSX
boston scientific corp
-1.8 M
MDT
medtronic plc
-0.8 M
PODD
insulet corp
-0.3 M

Avidity Partners Management LP Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Avidity Partners Management LP

Avidity Partners Management LP has 45 stocks in it's portfolio. About 81.9% of the portfolio is in top 10 stocks. CNTX proved to be the most loss making stock for the portfolio. was the most profitable stock for Avidity Partners Management LP last quarter.

$624.44MTotal Value
61.00Positions
14 Aug, 2026Last Reported
Current holdings of Current Stock Holdings of Avidity Partners Management LP, last reported on 14 Aug, 2026. Select a row with a linked ticker to view its historical trend.
ExpandHoldingsorted ascending% PortfolioShares Held$ Value% Change
GMAB
Genmab A/S

Genmab A/S

GMAB
Avidity Partners Management LP's holding in Genmab A/S over time
0.22%50,000
$1.37M
0.22%
decreased 50 percentreduced
ICLR
Icon Plc

Icon Plc

ICLR
Avidity Partners Management LP's holding in Icon Plc over time
0%0.00
$0.00
0%
decreased 100 percentsold off