Latest Knott David M Jr Stock Portfolio

$189Million | No. of Holdings #84

Knott David M Jr Performance

2026 Q2+13.49%
YTD+4.63%
2025+10.40%

About Knott David M Jr and 13F Hedge Fund Stock Holdings

On 2026-08-12, the fund reported it's updated stock portfolio. In the 13F Holdings report, Knott David M Jr reported an equity portfolio of $189.2 Millions as of 30 Jun, 2026. <br><br> The top stock holdings of Knott David M Jr are GOOG, , SNDX. The fund has invested 17.1% of it's portfolio in ALPHABET INC-CL C and 14.1% of portfolio in APOLLO GLOBAL MANAGEMENT, INC. <br><br> The fund managers got completely rid off CATALYST PHARMACEUTICALS, INC. (CPRX), ARCELLX INC (ACLX) and CYTOKINETICS, INCORPORATED (CYTK) stocks. They significantly reduced their stock positions in BRISTOL-MYERS SQUIBB COMPANY (BMY), OCCIDENTAL PETROLEUM CORPORATION (OXY) and TG THERAPEUTICS, INC. (TGTX). Knott David M Jr opened new stock positions in CATALYST PHARMACEUTICALS, INC. (CLST), SPRUCE BIOSCIENCES, INC. (SPRB) and DUPONT DE NEMOURS, INC.. The fund showed a lot of confidence in some stocks as they added substantially to CULLINAN THERAPEUTICS, INC. (CGEM), MADRIGAL PHARMAACEUTICALS, INC. (MDGL) and VERASTEM INC. (VSTM).
Knott David M Jr Equity Portfolio Value
Last Reported on: 12 Aug, 2026
$189Million
  as of Aug 12, 2026

Knott David M Jr Annual Return Estimates Vs S&P 500

Our best estimate is that Knott David M Jr made a return of 13.49% in the last quarter. In trailing 12 months, it's portfolio return was 30.33%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
catalyst pharmaceuticals, inc.3,583,020
spruce biosciences, inc.1,080,000
dupont de nemours, inc.510,956
insmed incorporated453,455
lb pharmaceuticals, inc.420,779
caredx, inc.388,455
q32 bio inc387,449
enliven therapeutics, inc.313,787

New stocks bought by Knott David M Jr

Additions to existing portfolio by Knott David M Jr

Reductions

Ticker% Reduced
bristol-myers squibb company-85.32
occidental petroleum corporation-29.26
tg therapeutics, inc.-25.74
jpmorgan chase & co.-7.08

Knott David M Jr reduced stake in above stock

Sold off

Ticker$ Sold
mereo biopharm group plc-99,111
jasper therapeutics, inc.-140,883
catalyst pharmaceuticals, inc.-2,971,200
evolus, inc.-408,279
biohaven pharmaceutical holding co. ltd-513,691
adma biologics, inc.-542,402
centessa pharmaceuticals plc-1,549,080
lenz therapeutics, inc.-308,648

Knott David M Jr got rid off the above stocks

Sector Distribution

Knott David M Jr has about 49.2% of it's holdings in Healthcare sector.

  • Healthcare
  • Others
  • Communication Services
  • Financial Services
  • Technology
Sector%
Healthcare49.2
Others25.7
Communication Services17.1
Financial Services6
Technology1.3

Market Cap. Distribution

Knott David M Jr has about 28.6% of it's portfolio invested in the large-cap and mega-cap stocks.

  • UNALLOCATED
  • MID-CAP
  • MEGA-CAP
  • SMALL-CAP
  • LARGE-CAP
  • MICRO-CAP
Category%
UNALLOCATED25.7
MID-CAP23.4
MEGA-CAP22.3
SMALL-CAP19.1
LARGE-CAP6.3
MICRO-CAP3.2

Stocks belong to which Index?

About 67% of the stocks held by Knott David M Jr either belong to S&P 500 or RUSSELL 2000 index.

  • RUSSELL 2000
  • Others
  • S&P 500
Index%
RUSSELL 200043.2
Others33
S&P 50023.8
Top 5 Winners (%)%
TVTX
travere therapeutics, inc.
87.4 %
RZLT
rezolute, inc.
70.5 %
TGTX
tg therapeutics, inc.
57.0 %
URI
united rental, inc.
55.5 %
UNH
united healthcare corp.
53.6 %
Top 5 Winners ($)$
GOOG
alphabet inc-cl c
6.1 M
TVTX
travere therapeutics, inc.
3.9 M
XERS
xeris biopharma holdings, inc.
2.2 M
ALKS
alkermes plc
2.1 M
TGTX
tg therapeutics, inc.
1.7 M
Top 5 Losers (%)%
DOW
dow inc.
-34.3 %
ADGI
invivyd, inc.
-32.9 %
VSTM
verastem inc.
-24.4 %
WVE
wave life science ltd.
-19.9 %
CNQ
canadian natural resources limited
-18.9 %
Top 5 Losers ($)$
SNDX
syndax pharmaceutical, inc.
-0.6 M
lpl financial holdings inc.
-0.3 M
DCGO
docgo, inc.
-0.3 M
VRDN
viridian therapeutics, inc.
-0.2 M
ARDX
ardelyx, inc.
-0.2 M

Knott David M Jr Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Knott David M Jr

Knott David M Jr has 84 stocks in it's portfolio. About 62.8% of the portfolio is in top 10 stocks. SNDX proved to be the most loss making stock for the portfolio. GOOG was the most profitable stock for Knott David M Jr last quarter.

$189.18MTotal Value
96.00Positions
12 Aug, 2026Last Reported
Current holdings of Current Stock Holdings of Knott David M Jr, last reported on 12 Aug, 2026. Select a row with a linked ticker to view its historical trend.
ExpandHoldingsorted ascending% PortfolioShares Held$ Value% Change
BIL
Spdr S&P Biotech Etf

Spdr S&P Biotech Etf

BIL
Knott David M Jr's holding in Spdr S&P Biotech Etf over time
1.25%15,000
$2.37M
1.25%
unchanged 0 percentunchanged