Latest Knott David M Jr Stock Portfolio

Knott David M Jr Performance:

2025 Q4: 9.81%YTD: 10.4%2024: 20.36%

Performance for 2025 Q4 is 9.81%, and YTD is 10.4%, and 2024 is 20.36%.

About Knott David M Jr and 13F Hedge Fund Stock Holdings

On 2026-02-12, the fund reported it's updated stock portfolio. In the 13F Holdings report, Knott David M Jr reported an equity portfolio of $215.9 Millions as of 31 Dec, 2025.

The top stock holdings of Knott David M Jr are , , GOOG. The fund has invested 20.4% of it's portfolio in CALUMET, INC. and 15.1% of portfolio in APOLLO GLOBAL MANAGEMENT, INC.

The fund managers got completely rid off AVADEL PHARMACEUTICALS PLC, VERONA PHARMA PLC. (VRNA) and CSX CORPORATION (CSX) stocks. They significantly reduced their stock positions in CORTEVA, INC. (CTVA), DUPONT DE NEMOURS, INC. (DD) and DAY ONE BIOPHARMACEUTICALS, INC. (DAWN). Knott David M Jr opened new stock positions in COGENT BIOSCIENCES INC. (COGT), TG THERAPEUTICS, INC. (TGTX) and BIOHAVEN LTD. The fund showed a lot of confidence in some stocks as they added substantially to ALKERMES PLC (ALKS), PELTHOS THERAPEUTICS, INC. and BIOGEN INC. (BIIB).

Knott David M Jr Annual Return Estimates Vs S&P 500

Our best estimate is that Knott David M Jr made a return of 9.81% in the last quarter. In trailing 12 months, it's portfolio return was 10.4%.

Performance
S&P 500

New Buys

Ticker	$ Bought
cogent biosciences inc.	3,623,040
tg therapeutics, inc.	1,341,450
biohaven ltd	1,250,030
adma biologics, inc.	1,098,050
evolus, inc.	660,598
nektar therapeutics	655,340
connect biopharma holdings limited	564,000
agios pharmaceutical, inc.	489,960

New stocks bought by Knott David M Jr

Additions

Ticker	% Inc.
alkermes plc	392
pelthos therapeutics, inc.	215
biogen inc.	200
spdr s&p biotech etf	160
cybin inc	103
uniqure n.v.	100
scholar rock holding corporation	54.59
orchestra biomed holdings, inc.	28.21

Additions to existing portfolio by Knott David M Jr

Reductions

Ticker	% Reduced
corteva, inc.	-89.09
dupont de nemours, inc.	-83.26
day one biopharmaceuticals, inc.	-80.17
ryman hospitality properties, inc.	-80.00
janus henderson aaa clo etf	-78.63
mondelez international inc.	-62.5
ultragenyx pharmaceutical inc.	-61.53
kimberly-clark corporation	-60.00

Knott David M Jr reduced stake in above stock

Sold off

Ticker	$ Sold
avadel pharmaceuticals plc	-5,543,010
liquidia corporation	-2,450,980
csx corporation	-2,484,650
verona pharma plc.	-4,092,860
biocryst pharmaceuticals, inc.	-247,206
praxis precision medicines, inc.	-1,484,000
abbvie inc.	-1,166,270
fs kkr capital corp.	-42,924

Knott David M Jr got rid off the above stocks

Sector Distribution

Knott David M Jr has about 43.6% of it's holdings in Others sector.

Sector	%
Others	43.6
Healthcare	37.4
Communication Services	13.3
Financial Services	3.8
Technology	1.2

Market Cap. Distribution

Knott David M Jr has about 23.5% of it's portfolio invested in the large-cap and mega-cap stocks.

Category	%
UNALLOCATED	43.6
MID-CAP	20.6
MEGA-CAP	18.1
SMALL-CAP	10.3
LARGE-CAP	5.4
MICRO-CAP	1.8

Stocks belong to which Index?

About 53.7% of the stocks held by Knott David M Jr either belong to S&P 500 or RUSSELL 2000 index.

Index	%
Others	46.3
RUSSELL 2000	33.7
S&P 500	20

Top 5 Winners (%)		%
WVE	wave life science ltd.	132.2 %
ADGI	invivyd, inc.	124.5 %
VERA	vera therapeutics, inc.	74.3 %
RCUS	arcus biosciences, inc.	62.1 %
	orchestra biomed holdings, inc.	55.8 %

Top 5 Winners ($)		$
GOOG	alphabet inc-cl c	7.2 M
	calumet, inc.	4.1 M
TVTX	travere therapeutics, inc.	3.2 M
	apollo global management, inc.	2.6 M
SNDX	syndax pharmaceutical, inc.	2.4 M

Top 5 Losers (%)		%
MREO	mereo biopharm group plc	-79.8 %
RZLT	rezolute, inc.	-73.0 %
	lenz therapeutics, inc.	-54.3 %
QURE	uniqure n.v.	-51.9 %
DCGO	docgo, inc.	-33.1 %

Top 5 Losers ($)		$
RZLT	rezolute, inc.	-2.2 M
	lenz therapeutics, inc.	-2.1 M
DCGO	docgo, inc.	-1.4 M
MREO	mereo biopharm group plc	-0.5 M
ACLX	arcellx inc	-0.4 M

Knott David M Jr Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Knott David M Jr

Knott David M Jr has 87 stocks in it's portfolio. About 70.7% of the portfolio is in top 10 stocks. RZLT proved to be the most loss making stock for the portfolio. GOOG was the most profitable stock for Knott David M Jr last quarter.

Last Reported on: 12 Feb, 2026

Ticker	Namesorted ascending	% Portfolio	Shares Held	$ Value	Type	% Change
AAPL	apple inc.	0.31	2,494	678,019	unchanged	0.00

AB	alliancebernstein holding l.p.	0.86	48,000	1,847,040	unchanged	0.00

ABBV	abbvie inc.	0.00	0.00	0.00	sold off	-100

ACLX	arcellx inc	0.78	25,700	1,675,640	unchanged	0.00

ADGI	invivyd, inc.	0.11	100,000	247,000	unchanged	0.00

ADMA	adma biologics, inc.	0.51	60,200	1,098,050	new

AGIO	agios pharmaceutical, inc.	0.23	18,000	489,960	new

ALKS	alkermes plc	1.23	95,000	2,658,100	added	392

AMZN	amazon.com inc.	0.03	300	69,246	unchanged	0.00

ATRC	atricure, inc.	0.94	51,400	2,033,380	added	7.08

AVGO	broadcom, inc.	0.11	710	245,731	unchanged	0.00

BBIO	bridgebio pharma, inc.	3.01	85,000	6,501,650	unchanged	0.00

BCRX	biocryst pharmaceuticals, inc.	0.00	0.00	0.00	sold off	-100

BIIB	biogen inc.	0.49	6,000	1,055,940	added	200

BIL	spdr s&p biotech etf	0.73	13,000	1,585,090	added	160

BMY	bristol-myers squibb company	0.55	22,000	1,186,680	reduced	-18.52

BX	blackstone group lp	0.01	210	32,369	unchanged	0.00

CNQ	canadian natural resources limited	0.26	16,800	568,680	unchanged	0.00

CNTA	centessa pharmaceuticals plc	0.05	4,000	100,040	new

COGT	cogent biosciences inc.	1.68	102,000	3,623,040	new