Latest Knott David M Jr Stock Portfolio
Knott David M Jr Performance:
2025 Q3: 9.15%YTD: 8.88%2024: 16.55%
Performance for 2025 Q3 is 9.15%, and YTD is 8.88%, and 2024 is 16.55%.
About Knott David M Jr and 13F Hedge Fund Stock Holdings
In it's latest 13F Holdings report, Knott David M Jr reported an equity portfolio of $248 Millions as of 30 Sep, 2025.
The top stock holdings of Knott David M Jr are , , GOOG. The fund has invested 20.8% of it's portfolio in CALUMET, INC. and 12.1% of portfolio in APOLLO GLOBAL MANAGEMENT, INC.
The fund managers got completely rid off INOZYME PHARMA, INC. (INZY), ENSTAR GROUP LIMITED (ESGR) and MYRIAD GENETICS, INC. (MYGN) stocks. They significantly reduced their stock positions in BIOCRYST PHARMACEUTICALS, INC. (BCRX), ALKERMES PLC (ALKS) and VERONA PHARMA PLC. (VRNA). Knott David M Jr opened new stock positions in REZOLUTE, INC. (RZLT), CYTOKINETICS, INCORPORATED (CYTK) and PRAXIS PRECISION MEDICINES, INC. (PRAX). The fund showed a lot of confidence in some stocks as they added substantially to DAY ONE BIOPHARMACEUTICALS, INC. (DAWN), ISHARES BIOTECHNOLOGY ETF (IJR) and WAVE LIFE SCIENCE LTD. (WVE).
The top stock holdings of Knott David M Jr are , , GOOG. The fund has invested 20.8% of it's portfolio in CALUMET, INC. and 12.1% of portfolio in APOLLO GLOBAL MANAGEMENT, INC.
The fund managers got completely rid off INOZYME PHARMA, INC. (INZY), ENSTAR GROUP LIMITED (ESGR) and MYRIAD GENETICS, INC. (MYGN) stocks. They significantly reduced their stock positions in BIOCRYST PHARMACEUTICALS, INC. (BCRX), ALKERMES PLC (ALKS) and VERONA PHARMA PLC. (VRNA). Knott David M Jr opened new stock positions in REZOLUTE, INC. (RZLT), CYTOKINETICS, INCORPORATED (CYTK) and PRAXIS PRECISION MEDICINES, INC. (PRAX). The fund showed a lot of confidence in some stocks as they added substantially to DAY ONE BIOPHARMACEUTICALS, INC. (DAWN), ISHARES BIOTECHNOLOGY ETF (IJR) and WAVE LIFE SCIENCE LTD. (WVE).
Knott David M Jr Annual Return Estimates Vs S&P 500
Our best estimate is that Knott David M Jr made a return of 9.15% in the last quarter. In trailing 12 months, it's portfolio return was -1.77%.
New Buys
| Ticker | $ Bought |
|---|---|
| rezolute, inc. | 2,585,000 |
| cytokinetics, incorporated | 1,648,800 |
| praxis precision medicines, inc. | 1,484,000 |
| kura oncology, inc. | 595,623 |
| mondelez international inc. | 499,720 |
| fate therapeutics, inc. | 459,900 |
| jasper therapeutics, inc. | 407,906 |
| scholar rock holding corporation | 335,160 |
New stocks bought by Knott David M Jr
Additions
| Ticker | % Inc. |
|---|---|
| day one biopharmaceuticals, inc. | 287 |
| ishares biotechnology etf | 125 |
| wave life science ltd. | 125 |
| cybin inc | 109 |
| orchestra biomed holdings, inc. | 95.00 |
| spdr s&p biotech etf | 66.67 |
| arcus biosciences, inc. | 36.00 |
| vera therapeutics, inc. | 30.00 |
Additions to existing portfolio by Knott David M Jr
Reductions
| Ticker | % Reduced |
|---|---|
| biocryst pharmaceuticals, inc. | -90.21 |
| alkermes plc | -60.61 |
| verona pharma plc. | -30.26 |
| avadel pharmaceuticals plc | -14.79 |
| calumet, inc. | -13.74 |
| janus henderson aaa clo etf | -11.61 |
| mereo biopharm group plc | -5.95 |
| xeris biopharma holdings, inc. | -4.25 |
Knott David M Jr reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| inozyme pharma, inc. | -2,664,820 |
| autolus therapeutics plc | -615,600 |
| myriad genetics, inc. | -955,800 |
| atyr pharma, inc. | -255,361 |
| collegium pharmaceutical, inc. | -695,220 |
| mondelez international inc. | -606,960 |
| enstar group limited | -2,522,700 |
| axsome therapeutics, inc. | -626,340 |
Knott David M Jr got rid off the above stocks
Sector Distribution
Knott David M Jr has about 49.8% of it's holdings in Others sector.
| Sector | % |
|---|---|
| Others | 49.8 |
| Healthcare | 31.2 |
| Communication Services | 11.5 |
| Financial Services | 3.5 |
| Technology | 1.1 |
| Industrials | 1.1 |
Market Cap. Distribution
Knott David M Jr has about 20.2% of it's portfolio invested in the large-cap and mega-cap stocks.
| Category | % |
|---|---|
| UNALLOCATED | 50.1 |
| SMALL-CAP | 17.9 |
| MEGA-CAP | 16.2 |
| MID-CAP | 10.5 |
| LARGE-CAP | 4 |
| MICRO-CAP | 1.3 |
Stocks belong to which Index?
About 44.1% of the stocks held by Knott David M Jr either belong to S&P 500 or RUSSELL 2000 index.
| Index | % |
|---|---|
| Others | 55.8 |
| RUSSELL 2000 | 24 |
| S&P 500 | 20.1 |
Knott David M Jr Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Knott David M Jr
Knott David M Jr has 87 stocks in it's portfolio. About 68.4% of the portfolio is in top 10 stocks. DCGO proved to be the most loss making stock for the portfolio. GOOG was the most profitable stock for Knott David M Jr last quarter.
Last Reported on: 12 Nov, 2025| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| AAPL | apple inc. | 0.26 | 2,494 | 635,047 | unchanged | 0.00 | ||
| AB | alliancebernstein holding l.p. | 0.74 | 48,000 | 1,834,560 | unchanged | 0.00 | ||
| ABBV | abbvie inc. | 0.47 | 5,037 | 1,166,270 | unchanged | 0.00 | ||
| ACLX | arcellx inc | 0.85 | 25,700 | 2,109,970 | unchanged | 0.00 | ||
| ADGI | invivyd, inc. | 0.04 | 100,000 | 110,000 | new | |||
| ALKS | alkermes plc | 0.23 | 19,300 | 579,000 | reduced | -60.61 | ||
| AMZN | amazon.com inc. | 0.03 | 300 | 65,871 | unchanged | 0.00 | ||
| ATRC | atricure, inc. | 0.68 | 48,000 | 1,692,000 | added | 3.35 | ||
| AUTL | autolus therapeutics plc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| AVGO | broadcom, inc. | 0.09 | 710 | 234,236 | unchanged | 0.00 | ||
| AXSM | axsome therapeutics, inc. | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| BBIO | bridgebio pharma, inc. | 1.78 | 85,000 | 4,414,900 | added | 6.25 | ||
| BCRX | biocryst pharmaceuticals, inc. | 0.10 | 32,570 | 247,206 | reduced | -90.21 | ||
| BIIB | biogen inc. | 0.11 | 2,000 | 280,160 | new | |||
| BIL | spdr s&p biotech etf | 0.20 | 5,000 | 501,000 | added | 66.67 | ||
| BMY | bristol-myers squibb company | 0.49 | 27,000 | 1,217,700 | unchanged | 0.00 | ||
| BX | blackstone group lp | 0.01 | 210 | 35,878 | unchanged | 0.00 | ||
| COLL | collegium pharmaceutical, inc. | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| CPRX | catalyst pharmaceuticals, inc. | 1.50 | 189,000 | 3,723,300 | added | 7.39 | ||
| CRM | salesforce, inc. | 0.01 | 77.00 | 18,249 | unchanged | 0.00 | ||