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Latest Knott David M Jr Stock Portfolio

$168Million– No. of Holdings #85

Knott David M Jr Performance:
2026 Q1: -7.81%YTD: -7.81%2025: 10.4%
Performance for 2026 Q1 is -7.81%, and YTD is -7.81%, and 2025 is 10.4%.

About Knott David M Jr and 13F Hedge Fund Stock Holdings

On 2026-05-14, the fund reported it's updated stock portfolio. In the 13F Holdings report, Knott David M Jr reported an equity portfolio of $168 Millions as of 31 Mar, 2026.

The top stock holdings of Knott David M Jr are GOOG, , SNDX. The fund has invested 15.6% of it's portfolio in ALPHABET INC-CL C and 14.9% of portfolio in APOLLO GLOBAL MANAGEMENT, INC.

The fund managers got completely rid off CALUMET, INC., NEKTAR THERAPEUTICS (NKTR) and SCHOLAR ROCK HOLDING CORPORATION (SRRK) stocks. They significantly reduced their stock positions in SOLID BIOSCIENCE INC. (SLDB), WAVE LIFE SCIENCE LTD. (WVE) and BRISTOL-MYERS SQUIBB COMPANY (BMY). Knott David M Jr opened new stock positions in IOVANCE BIOTHERAPEUTICS, INC. (IOVA), LPL FINANCIAL HOLDINGS INC. and RELMADA THERAPEUTICS, INC. (RLMD). The fund showed a lot of confidence in some stocks as they added substantially to CENTESSA PHARMACEUTICALS PLC (CNTA), AGIOS PHARMACEUTICAL, INC. (AGIO) and TG THERAPEUTICS, INC. (TGTX).
Knott David M Jr Equity Portfolio Value
Last Reported on: 14 May, 2026

Knott David M Jr Annual Return Estimates Vs S&P 500

Our best estimate is that Knott David M Jr made a return of -7.81% in the last quarter. In trailing 12 months, it's portfolio return was 22.61%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
iovance biotherapeutics, inc.5,616,000
lpl financial holdings inc.4,963,700
relmada therapeutics, inc.3,057,530
ardelyx, inc.1,239,930
verastem inc.551,200
biohaven pharmaceutical holding co. ltd513,691
cullinan therapeutics, inc.343,882
rain enhancement technologies holdco inc258,282
New stocks bought by Knott David M Jr

Additions

Ticker% Inc.
centessa pharmaceuticals plc875
agios pharmaceutical, inc.416
tg therapeutics, inc.100
connect biopharma holdings limited93.92
ultragenyx pharmaceutical inc.65.3
kura oncology, inc.34.58
alkermes plc26.32
viridian therapeutics, inc.24.83
Additions to existing portfolio by Knott David M Jr

Reductions

Ticker% Reduced
solid bioscience inc.-70.98
wave life science ltd.-55.56
bristol-myers squibb company-38.08
lenz therapeutics, inc.-37.22
catalyst pharmaceuticals, inc.-36.51
biogen inc.-33.33
arcus biosciences, inc.-32.99
cytokinetics, incorporated-30.46
Knott David M Jr reduced stake in above stock

Sold off

Ticker$ Sold
calumet, inc.-44,011,400
fate therapeutics, inc.-358,649
rain enhancement technologies holdco inc-437,762
biohaven ltd-1,250,030
tectonic therapeutic, inc.-1,543,640
day one biopharmaceuticals, inc.-241,239
nektar therapeutics-655,340
scholar rock holding corporation-612,868
Knott David M Jr got rid off the above stocks

Sector Distribution

Knott David M Jr has about 50.7% of it's holdings in Healthcare sector.

  • Healthcare
  • Others
  • Communication Services
  • Financial Services
  • Technology
Sector%
Healthcare50.7
Others26.9
Communication Services15.7
Financial Services4.6
Technology1.3

Market Cap. Distribution

Knott David M Jr has about 27.8% of it's portfolio invested in the large-cap and mega-cap stocks.

  • UNALLOCATED
  • MID-CAP
  • MEGA-CAP
  • SMALL-CAP
  • LARGE-CAP
  • MICRO-CAP
Category%
UNALLOCATED26.9
MID-CAP23.6
MEGA-CAP21.1
SMALL-CAP18.6
LARGE-CAP6.7
MICRO-CAP3.1

Stocks belong to which Index?

About 67.5% of the stocks held by Knott David M Jr either belong to S&P 500 or RUSSELL 2000 index.

  • RUSSELL 2000
  • Others
  • S&P 500
Index%
RUSSELL 200044.3
Others32.5
S&P 50023.2
Top 5 Winners (%)%
DOW
dow inc.
78.2 %
ACLX
arcellx inc
66.8 %
OXY
occidential pertro wts exp. 8/3/27
47.5 %
CNQ
canadian natural resources limited
44.0 %
PWR
quanta services, inc.
30.1 %
Top 5 Winners ($)$
PTGX
protagonist therapeutics, inc
1.2 M
ACLX
arcellx inc
1.1 M
SNDX
syndax pharmaceutical, inc.
1.0 M
ALKS
alkermes plc
0.8 M
AGIO
agios pharmaceutical, inc.
0.4 M
Top 5 Losers (%)%
KD
kyndryl holdings inc.
-50.6 %
ADMA
adma biologics, inc.
-50.6 %
JSPR
jasper therapeutics, inc.
-49.2 %
ADGI
invivyd, inc.
-47.4 %
WVE
wave life science ltd.
-41.4 %
Top 5 Losers ($)$
apollo global management, inc.
-7.5 M
GOOG
alphabet inc-cl c
-2.5 M
XERS
xeris biopharma holdings, inc.
-2.1 M
VRDN
viridian therapeutics, inc.
-1.9 M
TVTX
travere therapeutics, inc.
-1.4 M

Knott David M Jr Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Knott David M Jr

Knott David M Jr has 85 stocks in it's portfolio. About 60.5% of the portfolio is in top 10 stocks. proved to be the most loss making stock for the portfolio. PTGX was the most profitable stock for Knott David M Jr last quarter.

Last Reported on: 14 May, 2026
TickerNamesorted ascending% PortfolioShares Held$ ValueType% ChangeOptions