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Latest DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) Stock Portfolio

$8.48Billion– No. of Holdings #73

DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) Performance:
2026 Q1: 1.6%YTD: 1.6%2025: 33.28%

Performance for 2026 Q1 is 1.6%, and YTD is 1.6%, and 2025 is 33.28%.

About DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) and 13F Hedge Fund Stock Holdings

DEERFIELD MANAGEMENT COMPANY, L.P. is a hedge fund based in New York, NY. On 2026-05-15, the fund reported it's updated stock portfolio. In the 13F Holdings report, DEERFIELD MANAGEMENT COMPANY, L.P. reported an equity portfolio of $8.5 Billions as of 31 Mar, 2026.

The top stock holdings of DEERFIELD MANAGEMENT COMPANY, L.P. are NUVL, COGT, PRAX. The fund has invested 20.9% of it's portfolio in NUVALENT INC and 4.1% of portfolio in COGENT BIOSCIENCES INC.

The fund managers got completely rid off INDIVIOR PLC, PHREESIA INC (PHR) and VENTAS INC (VTR) stocks. They significantly reduced their stock positions in NEUROCRINE BIOSCIENCES INC (NBIX), IDEAYA BIOSCIENCES INC (IDYA) and REVOLUTION MEDICINES INC (RVMD). DEERFIELD MANAGEMENT COMPANY, L.P. opened new stock positions in INDIVIOR PHARMACEUTICALS INC, SYNDAX PHARMACEUTICALS INC (SNDX) and PFIZER INC (PFE). The fund showed a lot of confidence in some stocks as they added substantially to XENON PHARMACEUTICALS INC (XENE), MONOPAR THERAPEUTICS INC (MNPR) and INSPIRE MED SYS INC (INSP).
DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) Equity Portfolio Value
Last Reported on: 15 May, 2026

DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) Annual Return Estimates Vs S&P 500

Our best estimate is that DEERFIELD MANAGEMENT COMPANY, L.P. made a return of 1.6% in the last quarter. In trailing 12 months, it's portfolio return was 48.41%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
arrowhead pharmaceuticals in207,182,000
indivior pharmaceuticals inc94,420,600
syndax pharmaceuticals inc88,298,500
dianthus therapeutics inc85,582,700
pfizer inc85,363,200
zenas biopharma inc67,252,900
genmab a/s66,055,500
biomarin pharmaceutical inc48,104,400

New stocks bought by DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)

Additions

Ticker% Inc.
xenon pharmaceuticals inc198
monopar therapeutics inc89.82
inspire med sys inc79.51
tango therapeutics inc42.65
beta bionics inc41.11
belite bio inc30.02
legend biotech corp29.6
disc medicine inc28.53

Additions to existing portfolio by DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)

Reductions

Ticker% Reduced
neurocrine biosciences inc-48.49
ideaya biosciences inc-28.94
revolution medicines inc-20.65
catalyst pharmaceuticals inc-19.7
arrowhead pharmaceuticals in-14.17
vera therapeutics inc-8.32
centene corp del-8.23
embecta corp-7.89

DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) reduced stake in above stock

Sold off

Ticker$ Sold
lantheus hldgs inc-28,911,400
indivior plc-121,743,000
phreesia inc-33,823,800
calcimedica inc-8,567,000
cormedix inc-12,885,400
petco health & wellness co i-2,631,030
edgewise therapeutics inc-19,000,700
butterfly network inc-12,907

DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) got rid off the above stocks

Sector Distribution

DEERFIELD MANAGEMENT COMPANY, L.P. has about 86.8% of it's holdings in Healthcare sector.

  • Healthcare
  • Others
Sector%
Healthcare86.8
Others12.4

Market Cap. Distribution

DEERFIELD MANAGEMENT COMPANY, L.P. has about 18.8% of it's portfolio invested in the large-cap and mega-cap stocks.

  • MID-CAP
  • LARGE-CAP
  • SMALL-CAP
  • UNALLOCATED
  • MICRO-CAP
Category%
MID-CAP49.1
LARGE-CAP18.8
SMALL-CAP17.3
UNALLOCATED12.4
MICRO-CAP2.4

Stocks belong to which Index?

About 67.8% of the stocks held by DEERFIELD MANAGEMENT COMPANY, L.P. either belong to S&P 500 or RUSSELL 2000 index.

  • RUSSELL 2000
  • Others
  • S&P 500
Index%
RUSSELL 200059.2
Others32.2
S&P 5008.6
Top 5 Winners (%)%
DAWN
day one biopharmaceuticals i
130.0 %
PHGE
biomx inc
100.8 %
TNGX
tango therapeutics inc
96.2 %
ACHC
acadia healthcare company in
64.8 %
EHAB
enhabit inc
52.8 %
Top 5 Winners ($)$
UTHR
united therapeutics corp del
46.7 M
RVMD
revolution medicines inc
45.7 M
DAWN
day one biopharmaceuticals i
45.1 M
TNGX
tango therapeutics inc
42.5 M
ACHC
acadia healthcare company in
41.6 M
Top 5 Losers (%)%
TOI
the oncology institute inc
-63.6 %
beta bionics inc
-63.5 %
QSI
quantum si inc
-45.8 %
INSP
inspire med sys inc
-38.0 %
CERT
certara inc
-35.3 %
Top 5 Losers ($)$
INSP
inspire med sys inc
-85.6 M
CNC
centene corp del
-52.0 M
VERA
vera therapeutics inc
-40.5 M
SBTX
ars pharmaceuticals inc
-27.2 M
LEGN
legend biotech corp
-24.9 M

DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)

DEERFIELD MANAGEMENT COMPANY, L.P. has 73 stocks in it's portfolio. About 46% of the portfolio is in top 10 stocks. INSP proved to be the most loss making stock for the portfolio. UTHR was the most profitable stock for DEERFIELD MANAGEMENT COMPANY, L.P. last quarter.

Last Reported on: 15 May, 2026
TickerNamesorted ascending% PortfolioShares Held$ ValueType% ChangeOptions