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Latest PERCEPTIVE ADVISORS LLC Stock Portfolio

$6.66Billion | No. of Holdings #101

Joseph Edelman Performance

2026 Q2+16.76%
YTD+22.28%
2025+57.06%

About Joseph Edelman and 13F Hedge Fund Stock Holdings

On 2026-08-14, the fund reported it's updated stock portfolio. In the 13F Holdings report, Joseph Edelman reported an equity portfolio of $6.7 Billions as of 30 Jun, 2026. <br><br> The top stock holdings of Joseph Edelman are PRAX, AGLE, CELC. The fund has invested 10.2% of it's portfolio in PRAXIS PRECISION MEDICINES I and 5.8% of portfolio in SPYRE THERAPEUTICS INC. <br><br> The fund managers got completely rid off ASCENDIS PHARMA A/S (ASND), CENTESSA PHARMACEUTICALS PLC (CNTA) and ENGENE HOLDINGS INC stocks. They significantly reduced their stock positions in GUARDANT HEALTH INC (GH), ABIVAX SA and ADMA BIOLOGICS INC (ADMA). Joseph Edelman opened new stock positions in ASCENDIS PHARMA A/S, BIOGEN INC (BIIB) and UNITEDHEALTH GROUP INC (UNH). The fund showed a lot of confidence in some stocks as they added substantially to LEONABIO INC (ATHA), ADAPTIVE BIOTECHNOLOGIES COR (ADPT) and CORCEPT THERAPEUTICS INC (CORT).
Joseph Edelman Equity Portfolio Value
Last Reported on: 14 Aug, 2026
$6.66Billion
  as of Aug 14, 2026

Joseph Edelman Annual Return Estimates Vs S&P 500

Our best estimate is that PERCEPTIVE ADVISORS LLC made a return of 16.76% in the last quarter. In trailing 12 months, it's portfolio return was 94.29%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
ascendis pharma a/s310,388,000
kardigan inc195,586,000
avalyn pharmaceuticals inc88,070,700
biogen inc59,669,900
unitedhealth group inc48,548,100
charles riv labs intl inc31,750,600
danaher corp del24,762,400
adlai nortye ltd20,621,700
New stocks bought by PERCEPTIVE ADVISORS LLC

Additions

Ticker% Inc.
leonabio inc890
adaptive biotechnologies cor698
corcept therapeutics inc696
tango therapeutics inc317
surrozen inc119
irhythm holdings inc113
revolution medicines inc104
evolus inc91.11
Additions to existing portfolio by PERCEPTIVE ADVISORS LLC

Reductions

Ticker% Reduced
guardant health inc-86.22
abivax sa-77.5
adma biologics inc-75.65
twist bioscience corp-75.46
axogen inc-64.53
cumberland pharmaceuticals i-50.77
viridian therapeutics inc-50.29
phathom pharmaceuticals inc-42.49
PERCEPTIVE ADVISORS LLC reduced stake in above stock

Sold off

Ticker$ Sold
engene holdings inc-39,685,300
centessa pharmaceuticals plc-208,884,000
neumora therapeutics inc.-9,952,990
inhibikase therapeutics inc-3,889,200
opus genetics inc-8,353,080
day one biopharmaceuticals i-37,644,300
ascendis pharma a/s-350,282,000
evommune inc-10,307,600
PERCEPTIVE ADVISORS LLC got rid off the above stocks

Sector Distribution

PERCEPTIVE ADVISORS LLC has about 75.5% of it's holdings in Healthcare sector.

  • Healthcare
  • Others
Sector%
Healthcare75.5
Others24.3

Market Cap. Distribution

PERCEPTIVE ADVISORS LLC has about 9.7% of it's portfolio invested in the large-cap and mega-cap stocks.

  • MID-CAP
  • UNALLOCATED
  • LARGE-CAP
  • SMALL-CAP
  • MICRO-CAP
Category%
MID-CAP54.3
UNALLOCATED24.3
LARGE-CAP9.7
SMALL-CAP9.2
MICRO-CAP1.4

Stocks belong to which Index?

About 48.3% of the stocks held by PERCEPTIVE ADVISORS LLC either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • RUSSELL 2000
  • S&P 500
Index%
Others51.7
RUSSELL 200045.2
S&P 5003.1
Top 5 Winners (%)%
RVMD
revolution medicines inc
424.0 %
oruka therapeutics inc
92.3 %
TVTX
travere therapeutics inc
86.9 %
anteris technologies global
77.5 %
omada health inc
74.6 %
Top 5 Winners ($)$
AGLE
spyre therapeutics inc
155.3 M
TVTX
travere therapeutics inc
107.0 M
RLAY
relay therapeutics inc
104.5 M
apogee therapeutics inc
69.2 M
oruka therapeutics inc
63.2 M
Top 5 Losers (%)%
ATHA
leonabio inc
-84.7 %
NAUT
nautilus biotechnology inc
-49.8 %
ENSC
ensysce biosciences inc
-46.1 %
oculis holding ag
-42.5 %
adagio med hldgs inc
-41.5 %
Top 5 Losers ($)$
ATHA
leonabio inc
-94.8 M
CELC
celcuity inc
-30.1 M
NAUT
nautilus biotechnology inc
-24.3 M
AORT
artivion inc
-23.9 M
CTMX
cytomx therapeutics inc.
-9.8 M

Joseph Edelman Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Joseph Edelman

PERCEPTIVE ADVISORS LLC has 101 stocks in it's portfolio. About 47.3% of the portfolio is in top 10 stocks. ATHA proved to be the most loss making stock for the portfolio. AGLE was the most profitable stock for PERCEPTIVE ADVISORS LLC last quarter.

$6.44BTotal Value
115Positions
14 Aug, 2026Last Reported
Current holdings of Current Stock Holdings of Joseph Edelman, last reported on 14 Aug, 2026. Select a row with a linked ticker to view its historical trend.
ExpandHoldingsorted ascending% PortfolioShares Held$ Value% Change
ASND
Ascendis Pharma A/S

Ascendis Pharma A/S

ASND
Joseph Edelman's holding in Ascendis Pharma A/S over time
0%0.00
$0.00
0%
decreased 100 percentsold off
BLTE
Belite Bio Inc

Belite Bio Inc

BLTE
Joseph Edelman's holding in Belite Bio Inc over time
0%0.00
$0.00
0%
decreased 100 percentsold off