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Latest Partner Fund Management, L.P. Stock Portfolio

$1.10Billion– No. of Holdings #76

Partner Fund Management, L.P. Performance:
2026 Q1: -3.11%YTD: -3.11%2025: 29.32%
Performance for 2026 Q1 is -3.11%, and YTD is -3.11%, and 2025 is 29.32%.

About Partner Fund Management, L.P. and 13F Hedge Fund Stock Holdings

PFM Health Sciences, LP is a hedge fund based in San Francisco, CA. On 2026-05-15, the fund reported it's updated stock portfolio. In the 13F Holdings report, PFM Health Sciences, LP reported an equity portfolio of $1.1 Billions as of 31 Mar, 2026.

The top stock holdings of PFM Health Sciences, LP are THC, LLY, PEN. The fund has invested 6.9% of it's portfolio in TENET HEALTHCARE CORP and 5.5% of portfolio in ELI LILLY & CO.

The fund managers got completely rid off ADMA BIOLOGICS INC (ADMA), MEDTRONIC PLC (MDT) and MERCK & CO INC (MRK) stocks. They significantly reduced their stock positions in CENTENE CORP DEL (CNC), THERMO FISHER SCIENTIFIC INC (TMO) and STRYKER CORPORATION (SYK). PFM Health Sciences, LP opened new stock positions in INDIVIOR PHARMACEUTICALS INC, ABBOTT LABORATORIES (ABT) and ACADIA HEALTHCARE COMPANY IN (ACHC). The fund showed a lot of confidence in some stocks as they added substantially to MADRIGAL PHARMACEUTICALS INC (MDGL), JAZZ PHARMACEUTICALS PLC (JAZZ) and RHYTHM PHARMACEUTICALS INC (RYTM).
Partner Fund Management, L.P. Equity Portfolio Value
Last Reported on: 15 May, 2026

Partner Fund Management, L.P. Annual Return Estimates Vs S&P 500

Our best estimate is that PFM Health Sciences, LP made a return of -3.11% in the last quarter. In trailing 12 months, it's portfolio return was 20.64%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
indivior pharmaceuticals inc17,515,800
abbott laboratories14,418,200
acadia healthcare company in13,630,400
natera inc12,000,200
schein henry inc11,284,500
merit med sys inc11,199,000
terns pharmaceuticals inc9,118,560
oruka therapeutics inc8,537,250
New stocks bought by Partner Fund Management, L.P.

Additions

Ticker% Inc.
madrigal pharmaceuticals inc370
jazz pharmaceuticals plc252
rhythm pharmaceuticals inc239
belite bio inc199
mineralys therapeutics inc199
tarsus pharmaceuticals inc193
celldex therapeutics inc new144
structure therapeutics inc85.18
Additions to existing portfolio by Partner Fund Management, L.P.

Reductions

Ticker% Reduced
centene corp del-63.68
thermo fisher scientific inc-60.88
stryker corporation-56.82
icon plc-50.15
cardinal health inc-48.76
united therapeutics corp del-41.24
rezolute inc-37.59
amneal pharmaceuticals inc-36.53
Partner Fund Management, L.P. reduced stake in above stock

Sold off

Ticker$ Sold
adma biologics inc-23,181,100
indivior plc-12,941,700
medtronic plc-20,537,200
elanco animal health inc-4,691,450
merck & co inc-19,771,400
sanofi sa-8,548,970
fortrea hldgs inc-2,853,820
cvs health corp-8,552,390
Partner Fund Management, L.P. got rid off the above stocks

Sector Distribution

PFM Health Sciences, LP has about 81.1% of it's holdings in Healthcare sector.

  • Healthcare
  • Others
Sector%
Healthcare81.1
Others18.9

Market Cap. Distribution

PFM Health Sciences, LP has about 49.4% of it's portfolio invested in the large-cap and mega-cap stocks.

  • LARGE-CAP
  • MID-CAP
  • UNALLOCATED
  • SMALL-CAP
  • MEGA-CAP
Category%
LARGE-CAP41.2
MID-CAP22.8
UNALLOCATED18.9
SMALL-CAP8.5
MEGA-CAP8.2

Stocks belong to which Index?

About 49.1% of the stocks held by PFM Health Sciences, LP either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • RUSSELL 2000
  • S&P 500
Index%
Others50.9
RUSSELL 200028.2
S&P 50020.9
Top 5 Winners (%)%
dianthus therapeutics inc
67.1 %
cg oncology inc
62.4 %
CNTA
centessa pharmaceuticals plc
55.7 %
tectonic therapeutic inc
45.6 %
CGEM
cullinan therapeutics inc
37.3 %
Top 5 Winners ($)$
CNTA
centessa pharmaceuticals plc
8.2 M
dianthus therapeutics inc
5.8 M
UTHR
united therapeutics corp del
5.7 M
cg oncology inc
4.3 M
RVMD
revolution medicines inc
2.6 M
Top 5 Losers (%)%
NEO
neogenomics inc
-36.3 %
QURE
uniqure nv
-30.9 %
ICLR
icon plc
-29.4 %
SLNO
soleno therapeutics inc
-27.7 %
structure therapeutics inc
-25.4 %
Top 5 Losers ($)$
LLY
eli lilly & co
-10.4 M
NEO
neogenomics inc
-7.5 M
ICLR
icon plc
-6.2 M
CNC
centene corp del
-4.2 M
THC
tenet healthcare corp
-4.0 M

Partner Fund Management, L.P. Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Partner Fund Management, L.P.

PFM Health Sciences, LP has 76 stocks in it's portfolio. About 35.6% of the portfolio is in top 10 stocks. LLY proved to be the most loss making stock for the portfolio. CNTA was the most profitable stock for PFM Health Sciences, LP last quarter.

Last Reported on: 15 May, 2026
TickerNamesorted ascending% PortfolioShares Held$ ValueType% ChangeOptions