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Latest Partner Fund Management, L.P. Stock Portfolio

$1.17Billion | No. of Holdings #96

Partner Fund Management, L.P. Performance

2026 Q2+14.79%
YTD+11.22%
2025+29.32%

About Partner Fund Management, L.P. and 13F Hedge Fund Stock Holdings

PFM Health Sciences, LP is a hedge fund based in San Francisco, CA. On 2026-08-14, the fund reported it's updated stock portfolio. In the 13F Holdings report, PFM Health Sciences, LP reported an equity portfolio of $1.2 Billions as of 30 Jun, 2026. <br><br> The top stock holdings of PFM Health Sciences, LP are , AXSM, LLY. The fund has invested 5.3% of it's portfolio in ASCENDIS PHARMA A/S and 4.6% of portfolio in AXSOME THERAPEUTICS INC. <br><br> The fund managers got completely rid off GLAUKOS CORP (GKOS), CENTESSA PHARMACEUTICALS PLC (CNTA) and NEOGENOMICS INC (NEO) stocks. They significantly reduced their stock positions in COMPASS PATHWAYS PLC (CMPS), TENET HEALTHCARE CORP (THC) and NATERA INC (NTRA). PFM Health Sciences, LP opened new stock positions in ASCENDIS PHARMA A/S, HUMANA INC (HUM) and METTLER TOLEDO INTERNATIONAL (MTD). The fund showed a lot of confidence in some stocks as they added substantially to STRYKER CORPORATION (SYK), ICON PUB LTD CO (ICLR) and EUPRAXIA PHARMACEUTICALS INC.
Partner Fund Management, L.P. Equity Portfolio Value
Last Reported on: 14 Aug, 2026
$1.17Billion
  as of Aug 14, 2026

Partner Fund Management, L.P. Annual Return Estimates Vs S&P 500

Our best estimate is that PFM Health Sciences, LP made a return of 14.79% in the last quarter. In trailing 12 months, it's portfolio return was 33.51%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
ascendis pharma a/s62,191,400
humana inc37,487,600
mettler toledo international17,047,100
merck & co inc16,334,700
cytokinetics inc16,329,700
lantheus hldgs inc16,241,900
cvs health corp14,219,900
gilead sciences inc11,479,000
New stocks bought by Partner Fund Management, L.P.

Additions

Ticker% Inc.
stryker corporation157
icon pub ltd co137
eupraxia pharmaceuticals inc123
arrowhead pharmaceuticals in104
thermo fisher scientific inc92.13
kodiak sciences inc68.51
abivax sa62.26
unitedhealth group inc52.1
Additions to existing portfolio by Partner Fund Management, L.P.

Reductions

Ticker% Reduced
compass pathways plc-81.89
tenet healthcare corp-68.24
natera inc-63.21
caribou biosciences inc-62.97
penumbra inc-56.92
mineralys therapeutics inc-56.25
syndax pharmaceuticals inc-51.67
tarsus pharmaceuticals inc-49.42
Partner Fund Management, L.P. reduced stake in above stock

Sold off

Ticker$ Sold
ascendis pharma a/s-16,921,000
neogenomics inc-13,241,400
personalis inc-5,542,520
centessa pharmaceuticals plc-20,981,100
alignment healthcare inc-6,340,130
soleno therapeutics inc-8,309,070
glaukos corp-23,220,600
terns pharmaceuticals inc-9,118,560
Partner Fund Management, L.P. got rid off the above stocks

Sector Distribution

PFM Health Sciences, LP has about 77.1% of it's holdings in Healthcare sector.

  • Healthcare
  • Others
Sector%
Healthcare77.1
Others22.7

Market Cap. Distribution

PFM Health Sciences, LP has about 53.4% of it's portfolio invested in the large-cap and mega-cap stocks.

  • LARGE-CAP
  • UNALLOCATED
  • MID-CAP
  • MEGA-CAP
  • SMALL-CAP
Category%
LARGE-CAP43.5
UNALLOCATED22.6
MID-CAP21.2
MEGA-CAP9.9
SMALL-CAP2.4

Stocks belong to which Index?

About 58.9% of the stocks held by PFM Health Sciences, LP either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • S&P 500
  • RUSSELL 2000
Index%
Others41.1
S&P 50029.8
RUSSELL 200029.1
Top 5 Winners (%)%
QURE
uniqure nv
147.1 %
OSCR
oscar health inc
142.0 %
definium therapeutics inc
120.1 %
CNC
centene corp del
93.4 %
CMPS
compass pathways plc
92.0 %
Top 5 Winners ($)$
AXSM
axsome therapeutics inc.
18.3 M
LLY
eli lilly & co
14.7 M
RVMD
revolution medicines inc
12.8 M
UNH
unitedhealth group inc
10.6 M
JAZZ
jazz pharmaceuticals plc
8.8 M
Top 5 Losers (%)%
CAPR
capricor therapeutics inc
-20.6 %
HCA
hca healthcare inc
-14.3 %
ABT
abbott laboratories
-9.2 %
UTHR
united therapeutics corp del
-7.8 %
TARS
tarsus pharmaceuticals inc
-7.7 %
Top 5 Losers ($)$
UTHR
united therapeutics corp del
-2.3 M
ABT
abbott laboratories
-1.3 M
PEN
penumbra inc
-1.3 M
HCA
hca healthcare inc
-0.9 M
CAPR
capricor therapeutics inc
-0.8 M

Partner Fund Management, L.P. Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Partner Fund Management, L.P.

PFM Health Sciences, LP has 96 stocks in it's portfolio. About 33.9% of the portfolio is in top 10 stocks. UTHR proved to be the most loss making stock for the portfolio. AXSM was the most profitable stock for PFM Health Sciences, LP last quarter.

$1.15BTotal Value
109Positions
14 Aug, 2026Last Reported
Current holdings of Current Stock Holdings of Partner Fund Management, L.P., last reported on 14 Aug, 2026. Select a row with a linked ticker to view its historical trend.
ExpandHoldingsorted ascending% PortfolioShares Held$ Value% Change
ARGX
Argenx Se

Argenx Se

ARGX
Partner Fund Management, L.P.'s holding in Argenx Se over time
0.36%4,482
$4.16M
0.36%
decreased 1.17 percentreduced
ASND
Ascendis Pharma A/S

Ascendis Pharma A/S

ASND
Partner Fund Management, L.P.'s holding in Ascendis Pharma A/S over time
0%0.00
$0.00
0%
decreased 100 percentsold off
BLTE
Belite Bio Inc

Belite Bio Inc

BLTE
Partner Fund Management, L.P.'s holding in Belite Bio Inc over time
0.46%34,803
$5.36M
0.46%
decreased 41.44 percentreduced