Latest SPHERA FUNDS MANAGEMENT LTD. Stock Portfolio
$621Million
Equity Portfolio Value
Last Reported on: 15 Feb, 2024
About SPHERA FUNDS MANAGEMENT LTD. and it’s 13F Hedge Fund Stock Holdings
SPHERA FUNDS MANAGEMENT LTD. is a hedge fund based in New York, NY. On 31-Mar-2022, the fund reported that it had an AUM (Regulated Assets under Management) of $789.8 Millions. In it's latest 13F Holdings report, SPHERA FUNDS MANAGEMENT LTD. reported an equity portfolio of $549 Millions as of 30 Sep, 2023.
The top stock holdings of SPHERA FUNDS MANAGEMENT LTD. are , , JNJ. The fund has invested 4.9% of it's portfolio in SANOFI and 3.5% of portfolio in ASTRAZENECA PLC.
The fund managers got completely rid off NOVA LTD, SAGE THERAPEUTICS INC (SAGE) and QUALCOMM INC (QCOM) stocks. They significantly reduced their stock positions in SELECTA BIOSCIENCES INC (SELB), NICE LTD and PRAXIS PRECISION MEDICINES I (PRAX). SPHERA FUNDS MANAGEMENT LTD. opened new stock positions in CYTOKINETICS INC (CYTK), ADVANCED MICRO DEVICES INC (AMD) and META PLATFORMS INC (META). The fund showed a lot of confidence in some stocks as they added substantially to INHIBRX INC (INBX), TOWER SEMICONDUCTOR LTD and 89BIO INC (ETNB).
The top stock holdings of SPHERA FUNDS MANAGEMENT LTD. are , , JNJ. The fund has invested 4.9% of it's portfolio in SANOFI and 3.5% of portfolio in ASTRAZENECA PLC.
The fund managers got completely rid off NOVA LTD, SAGE THERAPEUTICS INC (SAGE) and QUALCOMM INC (QCOM) stocks. They significantly reduced their stock positions in SELECTA BIOSCIENCES INC (SELB), NICE LTD and PRAXIS PRECISION MEDICINES I (PRAX). SPHERA FUNDS MANAGEMENT LTD. opened new stock positions in CYTOKINETICS INC (CYTK), ADVANCED MICRO DEVICES INC (AMD) and META PLATFORMS INC (META). The fund showed a lot of confidence in some stocks as they added substantially to INHIBRX INC (INBX), TOWER SEMICONDUCTOR LTD and 89BIO INC (ETNB).
New Buys
| Ticker | $ Bought |
|---|---|
| NOVA LTD | 18,135,500 |
| GLOBAL E ONLINE LTD | 10,691,900 |
| TABOOLA.COM LTD | 7,469,020 |
| WIX COM LTD | 7,070,820 |
| PHARVARIS N V | 6,872,250 |
| SENTINELONE INC | 5,856,190 |
| INCYTE CORP | 5,623,220 |
| ENPHASE ENERGY INC | 4,598,470 |
New stocks bought by SPHERA FUNDS MANAGEMENT LTD.
Additions
| Ticker | % Inc. |
|---|---|
| VISTAGEN THERAPEUTICS INC | 708 |
| TEVA PHARMACEUTICAL INDS LTD | 311 |
| META PLATFORMS INC | 125 |
| ASTRIA THERAPEUTICS INC | 98.27 |
| NICE LTD | 80.67 |
| BIOGEN INC | 79.32 |
| CELLDEX THERAPEUTICS INC NEW | 75.36 |
| MINERALYS THERAPEUTICS INC | 63.28 |
Additions to existing portfolio by SPHERA FUNDS MANAGEMENT LTD.
Reductions
| Ticker | % Reduced |
|---|---|
| PRAXIS PRECISION MEDICINES I | -93.22 |
| REPLIMUNE GROUP INC | -91.3 |
| JASPER THERAPEUTICS INC | -87.46 |
| MORPHIC HLDG INC | -83.39 |
| SAREPTA THERAPEUTICS INC | -75.00 |
| GRACELL BIOTECHNOLOGIES INC | -67.16 |
| MEDIWOUND LTD | -54.87 |
| GILEAD SCIENCES INC | -50.00 |
SPHERA FUNDS MANAGEMENT LTD. reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| ENPHASE ENERGY INC | -17,329,900 |
| POINT BIOPHARMA GLOBAL INC | -6,354,120 |
| UNIQURE NV | -998,005 |
| MIRUM PHARMACEUTICALS INC | -3,611,370 |
| DISC MEDICINE INC | -5,233,480 |
| VERA THERAPEUTICS INC | -1,439,550 |
| CROWDSTRIKE HLDGS INC | -2,510,700 |
| CALLIDITAS THERAPEUTICS AB | -216,618 |
SPHERA FUNDS MANAGEMENT LTD. got rid off the above stocks
Current Stock Holdings of SPHERA FUNDS MANAGEMENT LTD.
Last Reported on: 15 Feb, 2024| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options |
|---|---|---|---|---|---|---|---|
| ABBV | ABBVIE INC | 1.15 | 46,000 | 7,128,620 | UNCHANGED | 0.00 | |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 1.12 | 36,230 | 6,934,780 | ADDED | 0.36 | |
| ALPN | ALPINE IMMUNE SCIENCES INC | 0.72 | 234,841 | 4,476,070 | ADDED | 30.47 | |
| AMD | ADVANCED MICRO DEVICES INC | 1.20 | 50,387 | 7,427,550 | ADDED | 4.28 | |
| AMLX | AMYLYX PHARMACEUTICALS INC | 0.44 | 183,650 | 2,703,330 | REDUCED | -5.16 | |
| AMZN | AMAZON COM INC | 1.36 | 55,676 | 8,459,410 | REDUCED | -41.58 | |
| ARBE | ARBE ROBOTICS LTD | 0.01 | 43,165 | 94,100 | NEW | ||
| ARWR | ARROWHEAD PHARMACEUTICALS IN | 0.71 | 144,899 | 4,433,910 | NEW | ||
| ATXS | ASTRIA THERAPEUTICS INC | 1.42 | 1,151,140 | 8,840,790 | ADDED | 98.27 | |
| AVGO | BROADCOM INC | 0.32 | 1,800 | 2,009,250 | NEW | ||
| AZN | ASTRAZENECA PLC | 1.95 | 180,060 | 12,127,000 | REDUCED | -36.83 | |
| BBIO | BRIDGEBIO PHARMA INC | 1.83 | 282,146 | 11,390,200 | REDUCED | -18.35 | |
| BIIB | BIOGEN INC | 1.93 | 46,346 | 11,993,000 | ADDED | 79.32 | |
| CALT | CALLIDITAS THERAPEUTICS AB | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| CGEN | COMPUGEN LTD | 0.24 | 769,239 | 1,523,090 | REDUCED | -41.69 | |
| CLDX | CELLDEX THERAPEUTICS INC NEW | 2.02 | 315,644 | 12,518,400 | ADDED | 75.36 | |
| COGT | COGENT BIOSCIENCES INC | 0.24 | 259,201 | 1,524,100 | REDUCED | -38.29 | |
| CRWD | CROWDSTRIKE HLDGS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| CYTK | CYTOKINETICS INC | 3.01 | 223,820 | 18,686,700 | REDUCED | -4.32 | |
| DAWN | DAY ONE BIOPHARMACEUTICALS I | 1.21 | 513,000 | 7,489,800 | REDUCED | -3.21 | |
| ELEV | ELEVATION ONCOLOGY INC | 0.08 | 900,000 | 483,300 | UNCHANGED | 0.00 | |
| ENPH | ENPHASE ENERGY INC | 0.74 | 34,800 | 4,598,470 | NEW | ||
| ENPH | ENPHASE ENERGY INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| ETNB | 89BIO INC | 0.74 | 408,674 | 4,564,890 | ADDED | 27.99 | |
| FIVN | FIVE9 INC | 0.19 | 15,000 | 1,180,350 | NEW | ||
| FRLN | FREELINE THERAPEUTICS HLDGS | 0.02 | 16,445 | 104,755 | NEW | ||
| FROG | JFROG LTD | 0.61 | 109,905 | 3,803,810 | NEW | ||
| FUSN | FUSION PHARMACEUTICALS INC | 1.68 | 1,085,640 | 10,433,000 | REDUCED | -19.84 | |
| GILD | GILEAD SCIENCES INC | 0.26 | 20,000 | 1,620,200 | REDUCED | -50.00 | |
| GLBE | GLOBAL E ONLINE LTD | 1.72 | 269,794 | 10,691,900 | NEW | ||
| GLUE | MONTE ROSA THERAPEUTICS INC | 0.04 | 48,511 | 274,087 | NEW | ||
| GOSS | GOSSAMER BIO INC | 0.20 | 1,338,090 | 1,221,010 | REDUCED | -30.76 | |
| GRCL | GRACELL BIOTECHNOLOGIES INC | 0.81 | 502,936 | 5,049,480 | REDUCED | -67.16 | |
| GSK | GSK PLC | 0.60 | 100,000 | 3,706,000 | UNCHANGED | 0.00 | |
| HOWL | WEREWOLF THERAPEUTICS INC | 0.39 | 626,810 | 2,419,490 | UNCHANGED | 0.00 | |
| ICL | ICL GROUP LTD | 0.34 | 420,000 | 2,104,200 | REDUCED | -10.64 | |
| IMTX | IMMATICS N.V | 1.05 | 621,111 | 6,540,300 | ADDED | 0.64 | |
| IMTX | IMMATICS N.V | 0.05 | 100,000 | 292,000 | UNCHANGED | 0.00 | |
| INBX | INHIBRX INC | 1.39 | 226,551 | 8,608,940 | REDUCED | -11.63 | |
| INCY | INCYTE CORP | 0.90 | 89,556 | 5,623,220 | NEW | ||
| INZY | INOZYME PHARMA INC | 1.07 | 1,562,910 | 6,657,980 | ADDED | 26.56 | |
| JNJ | JOHNSON & JOHNSON | 2.01 | 79,831 | 12,512,700 | REDUCED | -15.82 | |
| JSPR | JASPER THERAPEUTICS INC | 0.90 | 713,063 | 5,626,060 | REDUCED | -87.46 | |
| KURA | KURA ONCOLOGY INC | 1.63 | 703,287 | 10,113,300 | UNCHANGED | 0.00 | |
| KZR | KEZAR LIFE SCIENCES INC | 0.31 | 2,051,680 | 1,943,760 | UNCHANGED | 0.00 | |
| LLY | ELI LILLY & CO | 1.33 | 14,190 | 8,271,640 | UNCHANGED | 0.00 | |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 1.03 | 27,767 | 6,424,730 | REDUCED | -45.41 | |
| MDWD | MEDIWOUND LTD | 0.08 | 48,980 | 498,124 | REDUCED | -54.87 | |
| META | META PLATFORMS INC | 1.95 | 34,303 | 12,141,900 | ADDED | 125 | |
| MIRM | MIRUM PHARMACEUTICALS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| MORF | MORPHIC HLDG INC | 0.07 | 14,952 | 431,814 | REDUCED | -83.39 | |
| MRK | MERCK & CO INC | 2.17 | 123,600 | 13,474,900 | UNCHANGED | 0.00 | |
| MRUS | MERUS N V | 1.02 | 230,333 | 6,334,160 | REDUCED | -9.08 | |
| MSFT | MICROSOFT CORP | 1.44 | 23,848 | 8,967,800 | REDUCED | -30.76 | |
| NICE | NICE LTD | 2.17 | 67,718 | 13,510,400 | ADDED | 80.67 | |
| NVMI | NOVA LTD | 2.92 | 132,000 | 18,135,500 | NEW | ||
| NVO | NOVO-NORDISK A S | 1.55 | 93,080 | 9,629,130 | UNCHANGED | 0.00 | |
| NVS | NOVARTIS AG | 0.98 | 60,000 | 6,058,070 | UNCHANGED | 0.00 | |
| ORIC | ORIC PHARMACEUTICALS INC | 0.19 | 126,800 | 1,166,560 | NEW | ||
| PANW | PALO ALTO NETWORKS INC | 0.79 | 16,585 | 4,890,580 | REDUCED | -42.33 | |
| PFE | PFIZER INC | 0.42 | 90,000 | 2,591,100 | UNCHANGED | 0.00 | |
| PHVS | PHARVARIS N V | 1.11 | 245,000 | 6,872,250 | NEW | ||
| PLRX | PLIANT THERAPEUTICS INC | 0.56 | 193,554 | 3,505,260 | ADDED | 23.97 | |
| PMN | PROMIS NEUROSCIENCES INC | 0.34 | 1,834,040 | 2,109,150 | UNCHANGED | 0.00 | |
| PNT | POINT BIOPHARMA GLOBAL INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| PRAX | PRAXIS PRECISION MEDICINES I | 1.18 | 328,986 | 7,329,810 | REDUCED | -93.22 | |
| PTCT | PTC THERAPEUTICS INC | 0.61 | 136,525 | 3,762,630 | REDUCED | -37.51 | |
| QURE | UNIQURE NV | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | 1.55 | 201,044 | 9,613,920 | REDUCED | -22.42 | |
| RCKT | ROCKET PHARMACEUTICALS INC | 0.92 | 190,783 | 5,717,770 | REDUCED | -8.73 | |
| REPL | REPLIMUNE GROUP INC | 0.02 | 16,096 | 135,689 | REDUCED | -91.3 | |
| RIGL | RIGEL PHARMACEUTICALS INC | 0.29 | 1,228,130 | 1,780,780 | UNCHANGED | 0.00 | |
| RZLT | REZOLUTE INC | 0.16 | 996,710 | 989,235 | UNCHANGED | 0.00 | |
| S | SENTINELONE INC | 0.94 | 213,418 | 5,856,190 | NEW | ||
| SEDG | SOLAREDGE TECHNOLOGIES INC | 0.72 | 48,000 | 4,492,800 | NEW | ||
| SELB | CARTESIAN THERAPEUTICS INC | 0.08 | 752,137 | 518,523 | UNCHANGED | 0.00 | |
| SNDX | SYNDAX PHARMACEUTICALS INC | 2.69 | 772,964 | 16,703,800 | REDUCED | -0.01 | |
| SNY | SANOFI | 4.00 | 499,515 | 24,840,900 | UNCHANGED | 0.00 | |
| SRPT | SAREPTA THERAPEUTICS INC | 0.19 | 12,500 | 1,205,380 | REDUCED | -75.00 | |
| SWTX | SPRINGWORKS THERAPEUTICS INC | 1.00 | 170,270 | 6,214,860 | REDUCED | -46.78 | |
| TBLA | TABOOLA.COM LTD | 1.20 | 1,724,950 | 7,469,020 | NEW | ||
| TEVA | TEVA PHARMACEUTICAL INDS LTD | 4.15 | 2,469,100 | 25,777,400 | ADDED | 311 | |
| TSEM | TOWER SEMICONDUCTOR LTD | 2.60 | 528,300 | 16,123,700 | ADDED | 12.51 | |
| UPWK | UPWORK INC | 0.60 | 252,784 | 3,758,900 | NEW | ||
| VERA | VERA THERAPEUTICS INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 | |
| VIGL | VIGIL NEUROSCIENCE INC | 0.29 | 535,120 | 1,808,710 | NEW | ||
| VSTA | VISTAGEN THERAPEUTICS INC | 0.67 | 808,550 | 4,155,950 | ADDED | 708 | |
| VTYX | VENTYX BIOSCIENCES INC | 0.07 | 180,000 | 444,600 | NEW | ||
| WIX | WIX COM LTD | 1.14 | 57,477 | 7,070,820 | NEW | ||
| MINERALYS THERAPEUTICS INC | 1.03 | 743,591 | 6,394,880 | ADDED | 63.28 | ||
| SHL TELEMEDICINE LTD | 0.81 | 632,456 | 5,043,840 | ADDED | 0.03 | ||
| ENLIGHT RENEWABLE ENERGY LTD | 0.52 | 169,280 | 3,240,020 | NEW | |||
| CARGO THERAPEUTICS INC | 0.28 | 75,000 | 1,736,250 | NEW | |||
| APOGEE THERAPEUTICS INC | 0.14 | 30,000 | 838,200 | UNCHANGED | 0.00 | ||
| PRIME MEDICINE INC | 0.10 | 73,980 | 655,463 | NEW | |||
| PERSPECTIVE THERAPEUTICS INC | 0.00 | 25,671 | 10,320 | NEW | |||
| DISC MEDICINE INC | 0.00 | 0.00 | 0.00 | SOLD OFF | -100 |