Latest Prosight Management, LP Stock Portfolio

$580Million | No. of Holdings #36

Prosight Management, LP Performance

2026 Q2-1.83%
YTD-6.73%
2025+7.64%

About Prosight Management, LP and 13F Hedge Fund Stock Holdings

On 2026-08-14, the fund reported it's updated stock portfolio. In the 13F Holdings report, Prosight Management, LP reported an equity portfolio of $580.4 Millions as of 30 Jun, 2026. <br><br> The top stock holdings of Prosight Management, LP are GLPG, JANX, NKTR. The fund has invested 10.6% of it's portfolio in LAKEFRONT BIOTHERAPEUTICS NV and 10.1% of portfolio in JANUX THERAPEUTICS INC. <br><br> The fund managers got completely rid off CONCENTRA GROUP HOLDINGS PAR, TERNS PHARMACEUTICALS INC (TERN) and PHREESIA INC (PHR) stocks. They significantly reduced their stock positions in MEIRAGTX HLDGS PLC (MGTX), PROCEPT BIOROBOTICS CORP (PRCT) and GENEDX HOLDINGS CORP (SMFR). Prosight Management, LP opened new stock positions in INSMED INC (INSM), MINERALYS THERAPEUTICS INC and OPTION CARE HEALTH INC (OPCH). The fund showed a lot of confidence in some stocks as they added substantially to IRHYTHM HOLDINGS INC (IRTC), INTUITIVE SURGICAL INC (ISRG) and REIN THERAPEUTICS INC (ALRN).
Prosight Management, LP Equity Portfolio Value
Last Reported on: 14 Aug, 2026
$580Million
  as of Aug 14, 2026

Prosight Management, LP Annual Return Estimates Vs S&P 500

Our best estimate is that Prosight Management, LP made a return of -1.83% in the last quarter. In trailing 12 months, it's portfolio return was 14.74%.
  • Performance
  • S&P 500

New Buys

Ticker$ Bought
insmed inc40,047,400
mineralys therapeutics inc12,135,500
option care health inc5,676,920
pfizer inc3,259,610
everforth inc1,206,220

New stocks bought by Prosight Management, LP

Additions to existing portfolio by Prosight Management, LP

Reductions

Ticker% Reduced
meiragtx hldgs plc-96.58
procept biorobotics corp-86.21
genedx holdings corp-83.67
immuneering corp-70.13
coya therapeutics inc-59.56
onkure therapeutics inc-54.56
tectonic therapeutic inc-50.26
orthopediatrics corp-47.92

Prosight Management, LP reduced stake in above stock

Sold off

Ticker$ Sold
phreesia inc-9,218,000
schrodinger inc-5,800,170
concentra group holdings par-10,849,900
adicet bio inc-1,704,160
trueblue inc-974,008
upstream bio inc-2,170,110
terns pharmaceuticals inc-10,665,300
regenxbio inc-1,676,000

Prosight Management, LP got rid off the above stocks

Sector Distribution

Prosight Management, LP has about 78% of it's holdings in Healthcare sector.

  • Healthcare
  • Others
Sector%
Healthcare78
Others20.8

Market Cap. Distribution

Prosight Management, LP has about 26.3% of it's portfolio invested in the large-cap and mega-cap stocks.

  • SMALL-CAP
  • LARGE-CAP
  • MID-CAP
  • UNALLOCATED
  • MICRO-CAP
Category%
SMALL-CAP29.6
LARGE-CAP26.3
MID-CAP21.4
UNALLOCATED20.8
MICRO-CAP1.9

Stocks belong to which Index?

About 53.2% of the stocks held by Prosight Management, LP either belong to S&P 500 or RUSSELL 2000 index.

  • Others
  • RUSSELL 2000
  • S&P 500
Index%
Others46.9
RUSSELL 200042.1
S&P 50011.1
Top 5 Winners (%)%
ALKS
alkermes plc
42.6 %
ANTX
an2 therapeutics inc
39.9 %
coya therapeutics inc
34.0 %
MGTX
meiragtx hldgs plc
29.0 %
KURA
kura oncology inc
28.0 %
Top 5 Winners ($)$
ALKS
alkermes plc
7.7 M
KURA
kura oncology inc
7.6 M
MGTX
meiragtx hldgs plc
6.6 M
JANX
janux therapeutics inc
5.4 M
STTK
shattuck labs inc
2.8 M
Top 5 Losers (%)%
ADCT
adc therapeutics sa
-69.4 %
BSX
boston scientific corp
-27.7 %
ALRN
rein therapeutics inc
-14.7 %
ISRG
intuitive surgical inc
-8.9 %
PLRX
pliant therapeutics inc
-8.7 %
Top 5 Losers ($)$
ADCT
adc therapeutics sa
-21.6 M
BSX
boston scientific corp
-20.7 M
PRCT
procept biorobotics corp
-2.7 M
ALNY
alnylam pharmaceuticals inc
-2.6 M
NKTR
nektar therapeutics
-1.7 M

Prosight Management, LP Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Prosight Management, LP

Prosight Management, LP has 36 stocks in it's portfolio. About 70.7% of the portfolio is in top 10 stocks. ADCT proved to be the most loss making stock for the portfolio. ALKS was the most profitable stock for Prosight Management, LP last quarter.

$580.35MTotal Value
51.00Positions
14 Aug, 2026Last Reported
Current holdings of Current Stock Holdings of Prosight Management, LP, last reported on 14 Aug, 2026. Select a row with a linked ticker to view its historical trend.
ExpandHoldingsorted ascending% PortfolioShares Held$ Value% Change
ADCT
Adc Therapeutics Sa

Adc Therapeutics Sa

ADCT
Prosight Management, LP's holding in Adc Therapeutics Sa over time
1.44%7,824,750
$8.37M
1.44%
decreased 5.73 percentreduced
GLPG
Lakefront Biotherapeutics Nv

Lakefront Biotherapeutics Nv

GLPG
Prosight Management, LP's holding in Lakefront Biotherapeutics Nv over time
10.56%2,043,340
$61.26M
10.56%
increased 31.83 percentadded