Latest Prosight Management, LP Stock Portfolio
Prosight Management, LP Performance:
2025 Q3: 18.92%YTD: 4.05%2024: -20.31%
Performance for 2025 Q3 is 18.92%, and YTD is 4.05%, and 2024 is -20.31%.
About Prosight Management, LP and 13F Hedge Fund Stock Holdings
In it's latest 13F Holdings report, Prosight Management, LP reported an equity portfolio of $428.8 Millions as of 30 Sep, 2025.
The top stock holdings of Prosight Management, LP are , MGTX, ADCT. The fund has invested 9.3% of it's portfolio in GALAPAGOS NV and 7.8% of portfolio in MEIRAGTX HLDGS PLC.
The fund managers got completely rid off UNITEDHEALTH GROUP INC (UNH), MIRUM PHARMACEUTICALS INC (MIRM) and LIVANOVA PLC (LIVN) stocks. They significantly reduced their stock positions in PLIANT THERAPEUTICS INC (PLRX), PROTHENA CORP PLC (PRTA) and ARGENX SE. Prosight Management, LP opened new stock positions in INTUITIVE SURGICAL INC (ISRG), VERTEX PHARMACEUTICALS INC (VRTX) and BOSTON SCIENTIFIC CORP (BSX). The fund showed a lot of confidence in some stocks as they added substantially to ORTHOPEDIATRICS CORP (KIDS), DEXCOM INC (DXCM) and SELECT MED HLDGS CORP (SEM).
The top stock holdings of Prosight Management, LP are , MGTX, ADCT. The fund has invested 9.3% of it's portfolio in GALAPAGOS NV and 7.8% of portfolio in MEIRAGTX HLDGS PLC.
The fund managers got completely rid off UNITEDHEALTH GROUP INC (UNH), MIRUM PHARMACEUTICALS INC (MIRM) and LIVANOVA PLC (LIVN) stocks. They significantly reduced their stock positions in PLIANT THERAPEUTICS INC (PLRX), PROTHENA CORP PLC (PRTA) and ARGENX SE. Prosight Management, LP opened new stock positions in INTUITIVE SURGICAL INC (ISRG), VERTEX PHARMACEUTICALS INC (VRTX) and BOSTON SCIENTIFIC CORP (BSX). The fund showed a lot of confidence in some stocks as they added substantially to ORTHOPEDIATRICS CORP (KIDS), DEXCOM INC (DXCM) and SELECT MED HLDGS CORP (SEM).
Prosight Management, LP Annual Return Estimates Vs S&P 500
Our best estimate is that Prosight Management, LP made a return of 18.92% in the last quarter. In trailing 12 months, it's portfolio return was -6.11%.
New Buys
| Ticker | $ Bought |
|---|---|
| intuitive surgical inc | 21,785,000 |
| vertex pharmaceuticals inc | 8,028,620 |
| boston scientific corp | 7,429,640 |
| procept biorobotics corp | 2,747,810 |
| align technology inc | 2,434,530 |
| twist bioscience corp | 2,110,500 |
| akero therapeutics inc | 1,855,140 |
| schrodinger inc | 698,690 |
New stocks bought by Prosight Management, LP
Additions
| Ticker | % Inc. |
|---|---|
| orthopediatrics corp | 319 |
| dexcom inc | 178 |
| select med hldgs corp | 147 |
| concentra group holdings par | 95.45 |
| onkure therapeutics inc | 67.8 |
| caredx inc | 66.45 |
| immunovant inc | 45.7 |
| rein therapeutics inc | 32.71 |
Additions to existing portfolio by Prosight Management, LP
Reductions
| Ticker | % Reduced |
|---|---|
| pliant therapeutics inc | -97.55 |
| prothena corp plc | -92.53 |
| argenx se | -85.00 |
| cytomx therapeutics inc | -83.94 |
| amicus therapeutics inc | -50.88 |
| sight sciences inc | -49.53 |
| bridgebio pharma inc | -44.04 |
| zymeworks inc | -42.77 |
Prosight Management, LP reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| mural oncology pub ltd co | -2,223,000 |
| axogen inc | -3,068,480 |
| pepgen inc | -270,818 |
| erasca inc | -305,175 |
| mirum pharmaceuticals inc | -10,178,000 |
| livanova plc | -6,302,800 |
| unitedhealth group inc | -34,316,700 |
| lantheus hldgs inc | -2,830,390 |
Prosight Management, LP got rid off the above stocks
Sector Distribution
Prosight Management, LP has about 75.2% of it's holdings in Healthcare sector.
| Sector | % |
|---|---|
| Healthcare | 75.2 |
| Others | 24.7 |
Market Cap. Distribution
Prosight Management, LP has about 12.7% of it's portfolio invested in the large-cap and mega-cap stocks.
| Category | % |
|---|---|
| UNALLOCATED | 31.8 |
| MID-CAP | 27.8 |
| SMALL-CAP | 24 |
| LARGE-CAP | 12.7 |
| MICRO-CAP | 3.6 |
Stocks belong to which Index?
About 60.2% of the stocks held by Prosight Management, LP either belong to S&P 500 or RUSSELL 2000 index.
| Index | % |
|---|---|
| RUSSELL 2000 | 47.5 |
| Others | 39.9 |
| S&P 500 | 12.7 |
Prosight Management, LP Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Prosight Management, LP
Prosight Management, LP has 41 stocks in it's portfolio. About 55.8% of the portfolio is in top 10 stocks. DXCM proved to be the most loss making stock for the portfolio. ADCT was the most profitable stock for Prosight Management, LP last quarter.
Last Reported on: 14 Nov, 2025| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ACHC | acadia healthcare company in | 1.44 | 250,000 | 6,190,000 | added | 18.03 | ||
| ADCT | adc therapeutics sa | 6.97 | 7,472,300 | 29,889,200 | reduced | -28.62 | ||
| AKRO | akero therapeutics inc | 0.43 | 39,072 | 1,855,140 | new | |||
| ALGN | align technology inc | 0.57 | 19,442 | 2,434,530 | new | |||
| ALRN | rein therapeutics inc | 0.15 | 567,898 | 650,243 | added | 32.71 | ||
| AXGN | axogen inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| BBIO | bridgebio pharma inc | 3.20 | 264,500 | 13,738,100 | reduced | -44.04 | ||
| BSX | boston scientific corp | 1.73 | 76,100 | 7,429,640 | new | |||
| CDNA | caredx inc | 1.71 | 504,030 | 7,328,600 | added | 66.45 | ||
| CRBP | corbus pharmaceuticals hldgs | 1.01 | 343,400 | 4,344,010 | reduced | -40.78 | ||
| CRNX | crinetics pharmaceuticals in | 3.19 | 328,684 | 13,689,700 | added | 10.25 | ||
| CTMX | cytomx therapeutics inc | 0.42 | 564,800 | 1,801,710 | reduced | -83.94 | ||
| DXCM | dexcom inc | 3.06 | 195,217 | 13,136,200 | added | 178 | ||
| ERAS | erasca inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| FOLD | amicus therapeutics inc | 3.14 | 1,709,530 | 13,471,100 | reduced | -50.88 | ||
| IMVT | immunovant inc | 2.63 | 698,472 | 11,259,400 | added | 45.7 | ||
| ISRG | intuitive surgical inc | 5.08 | 48,711 | 21,785,000 | new | |||
| JANX | janux therapeutics inc | 4.93 | 865,350 | 21,149,200 | added | 1.34 | ||
| KIDS | orthopediatrics corp | 1.33 | 308,707 | 5,720,340 | added | 319 | ||
| KURA | kura oncology inc | 5.69 | 2,758,520 | 24,412,900 | reduced | -13.29 | ||