Latest Prosight Management, LP Stock Portfolio
$609Million– No. of Holdings #46
Prosight Management, LP Performance:
2026 Q1: -4.99%YTD: -4.99%2025: 7.64%
Performance for 2026 Q1 is -4.99%, and YTD is -4.99%, and 2025 is 7.64%.
About Prosight Management, LP and 13F Hedge Fund Stock Holdings
On 2026-05-15, the fund reported it's updated stock portfolio. In the 13F Holdings report, Prosight Management, LP reported an equity portfolio of $609.8 Millions as of 31 Mar, 2026.
The top stock holdings of Prosight Management, LP are NKTR, BSX, JANX. The fund has invested 8.7% of it's portfolio in NEKTAR THERAPEUTICS and 8.2% of portfolio in BOSTON SCIENTIFIC CORP.
The fund managers got completely rid off ICON PLC (ICLR), AMICUS THERAPEUTICS INC (FOLD) and SELECT MED HLDGS CORP (SEM) stocks. They significantly reduced their stock positions in ROIVANT SCIENCES LTD (ROIV), TECTONIC THERAPEUTIC INC and TRUEBLUE INC (TBI). Prosight Management, LP opened new stock positions in ALKERMES PLC (ALKS), SCHRODINGER INC (SDGR) and EMERGENT BIOSOLUTIONS INC (EBS). The fund showed a lot of confidence in some stocks as they added substantially to GENEDX HOLDINGS CORP (SMFR), ABIVAX SA and ALNYLAM PHARMACEUTICALS INC (ALNY).
The top stock holdings of Prosight Management, LP are NKTR, BSX, JANX. The fund has invested 8.7% of it's portfolio in NEKTAR THERAPEUTICS and 8.2% of portfolio in BOSTON SCIENTIFIC CORP.
The fund managers got completely rid off ICON PLC (ICLR), AMICUS THERAPEUTICS INC (FOLD) and SELECT MED HLDGS CORP (SEM) stocks. They significantly reduced their stock positions in ROIVANT SCIENCES LTD (ROIV), TECTONIC THERAPEUTIC INC and TRUEBLUE INC (TBI). Prosight Management, LP opened new stock positions in ALKERMES PLC (ALKS), SCHRODINGER INC (SDGR) and EMERGENT BIOSOLUTIONS INC (EBS). The fund showed a lot of confidence in some stocks as they added substantially to GENEDX HOLDINGS CORP (SMFR), ABIVAX SA and ALNYLAM PHARMACEUTICALS INC (ALNY).
Prosight Management, LP Equity Portfolio Value
Last Reported on: 15 May, 2026
Prosight Management, LP Annual Return Estimates Vs S&P 500
Our best estimate is that Prosight Management, LP made a return of -4.99% in the last quarter. In trailing 12 months, it's portfolio return was 18.03%.
- Performance
- S&P 500
New Buys
| Ticker | $ Bought |
|---|---|
| alkermes plc | 18,162,000 |
| schrodinger inc | 5,800,170 |
| emergent biosolutions inc | 5,304,680 |
| icu med inc | 3,545,170 |
| upstream bio inc | 2,170,110 |
| omeros corp | 1,845,890 |
| intuitive surgical inc | 1,843,960 |
| an2 therapeutics inc | 1,763,880 |
New stocks bought by Prosight Management, LP
Additions
| Ticker | % Inc. |
|---|---|
| genedx holdings corp | 851 |
| abivax sa | 517 |
| alnylam pharmaceuticals inc | 344 |
| boston scientific corp | 278 |
| onkure therapeutics inc | 163 |
| orthopediatrics corp | 121 |
| terns pharmaceuticals inc | 112 |
| shattuck labs inc | 110 |
Additions to existing portfolio by Prosight Management, LP
Reductions
| Ticker | % Reduced |
|---|---|
| roivant sciences ltd | -71.3 |
| tectonic therapeutic inc | -66.01 |
| trueblue inc | -43.71 |
| concentra group holdings par | -43.23 |
| immunovant inc | -27.76 |
| meiragtx hldgs plc | -18.06 |
| rocket pharmaceuticals inc | -8.08 |
| rein therapeutics inc | -7.00 |
Prosight Management, LP reduced stake in above stock
Sold off
| Ticker | $ Sold |
|---|---|
| amicus therapeutics inc | -16,376,000 |
| select med hldgs corp | -15,371,000 |
| avantor inc | -10,296,800 |
| caredx inc | -4,710,000 |
| icon plc | -20,044,200 |
| tempus ai inc | -2,066,750 |
| labcorp holdings inc | -8,663,390 |
| bridgebio pharma inc | -2,294,700 |
Prosight Management, LP got rid off the above stocks
Sector Distribution
Prosight Management, LP has about 73.1% of it's holdings in Healthcare sector.
- Healthcare
- Others
| Sector | % |
|---|---|
| Healthcare | 73.1 |
| Others | 21.2 |
| 5.5 |
Market Cap. Distribution
Prosight Management, LP has about 15.9% of it's portfolio invested in the large-cap and mega-cap stocks.
- SMALL-CAP
- UNALLOCATED
- LARGE-CAP
- MID-CAP
- MICRO-CAP
| Category | % |
|---|---|
| SMALL-CAP | 41.1 |
| UNALLOCATED | 21.2 |
| LARGE-CAP | 15.9 |
| MID-CAP | 14.1 |
| MICRO-CAP | 7.3 |
Stocks belong to which Index?
About 52% of the stocks held by Prosight Management, LP either belong to S&P 500 or RUSSELL 2000 index.
- Others
- RUSSELL 2000
- S&P 500
| Index | % |
|---|---|
| Others | 48 |
| RUSSELL 2000 | 43.5 |
| S&P 500 | 8.5 |
Prosight Management, LP Holdings Map
This heatmap illustrates the top 50 positions within the fund's portfolio.
Current Stock Holdings of Prosight Management, LP
Prosight Management, LP has 46 stocks in it's portfolio. About 65% of the portfolio is in top 10 stocks. SMFR proved to be the most loss making stock for the portfolio. NKTR was the most profitable stock for Prosight Management, LP last quarter.
Last Reported on: 15 May, 2026| Ticker | Namesorted ascending | % Portfolio | Shares Held | $ Value | Type | % Change | Options | |
|---|---|---|---|---|---|---|---|---|
| ACET | adicet bio inc | 0.28 | 250,244 | 1,704,160 | unchanged | 0.00 | ||
| ADCT | adc therapeutics sa | 5.10 | 8,300,000 | 31,125,000 | reduced | -2.09 | ||
| ALKS | alkermes plc | 2.98 | 513,632 | 18,162,000 | new | |||
| ALNY | alnylam pharmaceuticals inc | 4.12 | 76,000 | 25,146,100 | added | 344 | ||
| ALRN | rein therapeutics inc | 0.09 | 411,600 | 535,080 | reduced | -7.00 | ||
| ANTX | an2 therapeutics inc | 0.29 | 515,754 | 1,763,880 | new | |||
| AVTR | avantor inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| BBIO | bridgebio pharma inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| BSX | boston scientific corp | 8.19 | 795,547 | 49,920,600 | added | 278 | ||
| CDNA | caredx inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| CRBP | corbus pharmaceuticals hldgs | 1.07 | 697,108 | 6,545,840 | added | 1.94 | ||
| CRNX | crinetics pharmaceuticals in | 2.08 | 350,000 | 12,712,000 | added | 33.13 | ||
| EBS | emergent biosolutions inc | 0.87 | 639,118 | 5,304,680 | new | |||
| FOLD | amicus therapeutics inc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| GLPG | galapagos nv | 7.62 | 1,550,000 | 46,500,000 | added | 44.31 | ||
| ICLR | icon plc | 0.00 | 0.00 | 0.00 | sold off | -100 | ||
| ICUI | icu med inc | 0.58 | 27,450 | 3,545,170 | new | |||
| IMRX | immuneering corp | 0.11 | 123,409 | 650,365 | new | |||
| IMVT | immunovant inc | 0.72 | 175,825 | 4,367,490 | reduced | -27.76 | ||
| IRTC | irhythm holdings inc | 0.19 | 10,000 | 1,180,200 | new | |||