Latest Simplify Asset Management Inc. Stock Portfolio

Simplify Asset Management Inc. Performance:

2025 Q3: 4.33%YTD: 7.57%2024: 6.9%

Performance for 2025 Q3 is 4.33%, and YTD is 7.57%, and 2024 is 6.9%.

About Simplify Asset Management Inc. and 13F Hedge Fund Stock Holdings

In it's latest 13F Holdings report, Simplify Asset Management Inc. reported an equity portfolio of $5.4 Billions as of 30 Sep, 2025.

The top stock holdings of Simplify Asset Management Inc. are AGGH, IJR, IJR. The fund has invested 61.1% of it's portfolio in SIMPLIFY EXCHANGE TRADED FUN and 12.2% of portfolio in ISHARES TR.

The fund managers got completely rid off ADMA BIOLOGICS INC (ADMA), FLUOR CORP NEW (FLR) and RESMED INC (RMD) stocks. They significantly reduced their stock positions in PHILIP MORRIS INTL INC (PM), SIMPLIFY EXCHANGE TRADED FUN (AGGH) and GENEDX HOLDINGS CORP (SMFR). Simplify Asset Management Inc. opened new stock positions in SIMPLIFY EXCHANGE TRADED FUN (AGGH), ISHARES BITCOIN TRUST ETF and UNITED THERAPEUTICS CORP DEL (UTHR). The fund showed a lot of confidence in some stocks as they added substantially to SIMPLIFY EXCHANGE TRADED FUN (AGGH), UNITEDHEALTH GROUP INC (UNH) and REGENERON PHARMACEUTICALS (REGN).

Simplify Asset Management Inc. Annual Return Estimates Vs S&P 500

Our best estimate is that Simplify Asset Management Inc. made a return of 4.33% in the last quarter. In trailing 12 months, it's portfolio return was 4.9%.

New Buys

Ticker	$ Bought
simplify exchange traded fun	3,318,620,000
ishares bitcoin trust etf	41,340,000
united therapeutics corp del	8,350,660
mineralys therapeutics inc	8,294,090
direxion shs etf tr	6,359,110
abivax sa	5,217,020
merus n v	3,136,510
apellis pharmaceuticals inc	2,418,880

New stocks bought by Simplify Asset Management Inc.

Additions

Ticker	% Inc.
simplify exchange traded fun	3,586
unitedhealth group inc	624
regeneron pharmaceuticals	251
milestone pharmaceuticals in	186
delcath sys inc	144
abbvie inc	100
cvs health corp	80.82
nektar therapeutics	67.65

Additions to existing portfolio by Simplify Asset Management Inc.

Reductions

Ticker	% Reduced
philip morris intl inc	-95.33
simplify exchange traded fun	-94.76
simplify exchange traded fun	-75.16
genedx holdings corp	-72.44
pacira biosciences inc	-62.81
danaher corporation	-55.72
cardinal health inc	-47.38
simplify exchange traded fun	-42.77

Simplify Asset Management Inc. reduced stake in above stock

Sold off

Ticker	$ Sold
adma biologics inc	-6,940,540
athira pharma inc	-450,823
fluor corp new	-3,495,280
capricor therapeutics inc	-397,200
sanofi	-1,000,790
dexcom inc	-1,802,540
ultragenyx pharmaceutical in	-553,036
resmed inc	-2,581,290

Simplify Asset Management Inc. got rid off the above stocks

Sector Distribution

Simplify Asset Management Inc. has about 95.5% of it's holdings in Others sector.

Sector	%
Others	95.5
Healthcare	3.1

Market Cap. Distribution

Simplify Asset Management Inc. has about 1.3% of it's portfolio invested in the large-cap and mega-cap stocks.

Category	%
UNALLOCATED	95.5
LARGE-CAP	1.3

Stocks belong to which Index?

About 1.8% of the stocks held by Simplify Asset Management Inc. either belong to S&P 500 or RUSSELL 2000 index.

Index	%
Others	97.2
S&P 500	1.8

Top 5 Winners (%)		%
APLT	applied therapeutics inc	94.4 %
SNDX	syndax pharmaceuticals inc	52.4 %
NKTR	nektar therapeutics	48.3 %
LGND	ligand pharmaceuticals inc	46.0 %
LPTX	leap therapeutics inc	43.7 %

Top 5 Winners ($)		$
IJR	ishares tr	54.6 M
IJR	ishares tr	5.6 M
TSLA	tesla inc	3.1 M
ARQT	arcutis biotherapeutics inc	2.0 M
EYE	national vision hldgs inc	1.7 M

Top 5 Losers (%)		%
AGL	agilon health inc	-52.0 %
ISRG	intuitive surgical inc	-17.7 %
AKRO	akero therapeutics inc	-11.0 %
PM	philip morris intl inc	-10.9 %
VRTX	vertex pharmaceuticals inc	-10.8 %

Top 5 Losers ($)		$
PAGP	plains gp hldgs l p	-1.5 M
AKRO	akero therapeutics inc	-0.9 M
ISRG	intuitive surgical inc	-0.8 M
PM	philip morris intl inc	-0.6 M
DCTH	delcath sys inc	-0.3 M

Simplify Asset Management Inc. Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of Simplify Asset Management Inc.

Simplify Asset Management Inc. has 127 stocks in it's portfolio. About 85.6% of the portfolio is in top 10 stocks. PAGP proved to be the most loss making stock for the portfolio. IJR was the most profitable stock for Simplify Asset Management Inc. last quarter.

Last Reported on: 20 Oct, 2025

Ticker	Namesorted ascending	% Portfolio	Shares Held	$ Value	Type	% Change
ABBV	abbvie inc	0.16	36,883	8,539,890	added	100

ABC	cencora inc	0.04	7,406	2,314,600	reduced	-15.39

ABEO	abeona therapeutics inc	0.06	565,009	2,983,250	added	1.15

ABT	abbott labs	0.03	11,138	1,491,820	added	13.72

ACHV	achieve life sciences inc	0.07	1,184,510	3,731,210	unchanged	0.00

ACT	advisorshares tr	0.04	444,428	2,128,810	new

ADBE	adobe inc	0.01	1,717	605,672	new

ADMA	adma biologics inc	0.00	0.00	0.00	sold off	-100

ADSK	autodesk inc	0.00	868	275,738	new

AGGH	simplify exchange traded fun	61.13	33,159,700	3,318,620,000	new

AGGH	simplify exchange traded fun	1.63	4,627,620	88,693,900	added	17.82

AGGH	simplify exchange traded fun	1.51	1,634,810	82,067,600	reduced	-14.57

AGGH	simplify exchange traded fun	1.42	3,718,250	77,005,000	reduced	-28.4

AGGH	simplify exchange traded fun	0.72	1,553,380	39,191,700	reduced	-42.77

AGGH	simplify exchange traded fun	0.50	822,303	26,864,600	added	3,586

AGGH	simplify exchange traded fun	0.48	974,406	25,924,800	reduced	-2.56

AGGH	simplify exchange traded fun	0.17	337,443	9,303,400	added	16.38

AGGH	simplify exchange traded fun	0.13	273,188	7,173,920	reduced	-75.16

AGGH	simplify exchange traded fun	0.05	91,464	2,608,330	unchanged	0.00

AGGH	simplify exchange traded fun	0.04	158,400	2,155,820	reduced	-94.76