Latest ADAGE CAPITAL PARTNERS GP, L.L.C. Stock Portfolio

ADAGE CAPITAL PARTNERS GP, L.L.C. Performance:

2025 Q3: 7.59%YTD: 12.5%2024: 17.14%

Performance for 2025 Q3 is 7.59%, and YTD is 12.5%, and 2024 is 17.14%.

About ADAGE CAPITAL PARTNERS GP, L.L.C. and 13F Hedge Fund Stock Holdings

In it's latest 13F Holdings report, ADAGE CAPITAL PARTNERS GP, L.L.C. reported an equity portfolio of $63.1 Billions as of 30 Sep, 2025.

The top stock holdings of ADAGE CAPITAL PARTNERS GP, L.L.C. are NVDA, MSFT, AAPL. The fund has invested 6.7% of it's portfolio in NVIDIA CORPORATION and 5.6% of portfolio in MICROSOFT CORP.

The fund managers got completely rid off HESS CORP (HES), ARGENX SE and ANSYS INC (ANSS) stocks. They significantly reduced their stock positions in PACKAGING CORP AMER (PKG), ASTERA LABS INC and POTLATCHDELTIC CORPORATION (PCH). ADAGE CAPITAL PARTNERS GP, L.L.C. opened new stock positions in CHEVRON CORP NEW (CVX), VIPER ENERGY INC and APPLOVIN CORP (APP). The fund showed a lot of confidence in some stocks as they added substantially to M & T BK CORP (MTB), RESMED INC (RMD) and NOVARTIS AG.

ADAGE CAPITAL PARTNERS GP, L.L.C. Annual Return Estimates Vs S&P 500

Our best estimate is that ADAGE CAPITAL PARTNERS GP, L.L.C. made a return of 7.59% in the last quarter. In trailing 12 months, it's portfolio return was 13.93%.

New Buys

Ticker	$ Bought
chevron corp new	510,103,000
viper energy inc	179,126,000
applovin corp	176,905,000
cyberark software ltd	138,776,000
deere & co	116,036,000
robinhood mkts inc	100,770,000
abivax sa	83,000,700
hubspot inc	58,475,000

New stocks bought by ADAGE CAPITAL PARTNERS GP, L.L.C.

Additions

Ticker	% Inc.
novartis ag	1,351
fortune brands innovations i	1,038
weyerhaeuser co mtn be	712
cubesmart	614
waystar hldg corp	557
black hills corp	475
89bio inc	362
acadia pharmaceuticals inc	311

Additions to existing portfolio by ADAGE CAPITAL PARTNERS GP, L.L.C.

Reductions

Ticker	% Reduced
palo alto networks inc	-83.49
textron inc	-78.27
madrigal pharmaceuticals inc	-76.47
southern co	-70.17
colgate palmolive co	-66.69
xylem inc	-65.54
ionis pharmaceuticals inc	-65.39
hanover ins group inc	-64.52

ADAGE CAPITAL PARTNERS GP, L.L.C. reduced stake in above stock

Sold off

None of the stocks were completely sold off by ADAGE CAPITAL PARTNERS GP, L.L.C.

Sector Distribution

ADAGE CAPITAL PARTNERS GP, L.L.C. has about 29.7% of it's holdings in Technology sector.

Sector	%
Technology	29.7
Healthcare	13.1
Financial Services	9.7
Consumer Cyclical	9.3
Industrials	8.4
Communication Services	8.4
Others	6.6
Consumer Defensive	4.2
Energy	4.1
Utilities	2.5
Real Estate	2.4
Basic Materials	1.7

Market Cap. Distribution

ADAGE CAPITAL PARTNERS GP, L.L.C. has about 82.8% of it's portfolio invested in the large-cap and mega-cap stocks.

Category	%
MEGA-CAP	45.1
LARGE-CAP	37.7
UNALLOCATED	6.8
MID-CAP	6.7
SMALL-CAP	3.1

Stocks belong to which Index?

About 85% of the stocks held by ADAGE CAPITAL PARTNERS GP, L.L.C. either belong to S&P 500 or RUSSELL 2000 index.

Index	%
S&P 500	78.5
Others	15.1
RUSSELL 2000	6.5

Top 5 Winners (%)		%
KOD	kodiak sciences inc	338.9 %
PEPG	pepgen inc	241.7 %
OVID	ovid therapeutics inc	174.5 %
ATAI	atai life sciences nv	141.6 %
PGEN	precigen inc	131.7 %

Top 5 Winners ($)		$
AAPL	apple inc	663.3 M
NVDA	nvidia corporation	644.4 M
GOOG	alphabet inc	355.7 M
TSLA	tesla inc	319.8 M
GOOG	alphabet inc	286.5 M

Top 5 Losers (%)		%
AEVA	aeva technologies inc	-47.9 %
MOH	molina healthcare inc	-35.8 %
CNC	centene corp del	-34.3 %
ALGN	align technology inc	-33.9 %
IT	gartner inc	-33.8 %

Top 5 Losers ($)		$
SLNO	soleno therapeutics inc	-57.9 M
NFLX	netflix inc	-55.2 M
CMG	chipotle mexican grill inc	-48.6 M
DOV	dover corp	-39.0 M
CRM	salesforce inc	-36.7 M

ADAGE CAPITAL PARTNERS GP, L.L.C. Holdings Map

This heatmap illustrates the top 50 positions within the fund's portfolio.

Current Stock Holdings of ADAGE CAPITAL PARTNERS GP, L.L.C.

ADAGE CAPITAL PARTNERS GP, L.L.C. has 871 stocks in it's portfolio. About 32.1% of the portfolio is in top 10 stocks. SLNO proved to be the most loss making stock for the portfolio. AAPL was the most profitable stock for ADAGE CAPITAL PARTNERS GP, L.L.C. last quarter.

Last Reported on: 14 Nov, 2025

Ticker	Namesorted ascending	% Portfolio	Shares Held	$ Value	Type	% Change
AAPL	apple inc	5.39	13,366,700	3,403,550,000	reduced	-0.33

ABBV	abbvie inc	0.68	1,844,790	427,143,000	added	13.96

ABC	cencora inc	0.09	176,300	55,099,000	added	7.99

ABNB	airbnb inc	0.07	350,600	42,569,900	added	10.11

ABT	abbott labs	0.49	2,296,990	307,658,000	added	43.77

ABUS	arbutus biopharma corp	0.04	5,014,940	22,767,800	added	94.68

ACAD	acadia pharmaceuticals inc	0.08	2,484,160	53,011,900	added	311

ACN	accenture plc ireland	0.21	546,422	134,748,000	added	4.39

ADBE	adobe inc	0.20	365,778	129,028,000	added	1.08

ADI	analog devices inc	0.14	370,514	91,035,300	reduced	-8.18

ADM	archer daniels midland co	0.04	437,392	26,129,800	reduced	-0.61

ADP	automatic data processing in	0.11	238,376	69,963,400	reduced	-39.92

ADSK	autodesk inc	0.09	169,589	53,873,300	reduced	-0.82

AEE	ameren corp	0.04	246,190	25,697,300	new

AFL	aflac inc	0.06	368,174	41,125,000	added	79.01

AGIO	agios pharmaceuticals inc	0.05	800,000	32,112,000	added	1.14

AIG	american intl group inc	0.09	752,276	59,083,800	added	19.82

AJG	gallagher arthur j & co	0.14	293,103	90,785,700	reduced	-40.74

ALGM	allegro microsystems inc	0.07	1,576,630	46,037,500	reduced	-27.6

ALL	allstate corp	0.11	325,619	69,894,100	added	214